scholarly journals Rare case of parathyroid gland sarcoidosis presenting with hypercalcaemia

2019 ◽  
Vol 12 (7) ◽  
pp. e230598 ◽  
Author(s):  
Biplab Kumar Saha ◽  
Stacey L Burns ◽  
Llewellyn A Foulke ◽  
Marc A Judson
Keyword(s):  
Soft Tissue ◽  
Parathyroid Gland ◽  
World Literature ◽  
Soft Tissue Mass ◽  
Rare Condition ◽  
B Cell Lymphoma ◽  
Tissue Mass ◽  
Positron Emission ◽  
History Of ◽  
Thoracic And Abdominal

Sarcoidosis of the parathyroid gland is a rare occurrence. Parathyroid sarcoidosis is usually associated with parathyroid adenomas, and, therefore, hypercalcaemia is a common presentation of this entity. We present a case of parathyroid sarcoidosis and review the world literature regarding this rare condition. A woman with a history of diffuse large B cell lymphoma underwent a surveillance positron emission tomography scan that showed increased fluorodeoxyglucose uptake in multiple thoracic and abdominal lymph nodes and in a left upper extremity soft tissue mass. Biopsy of the soft tissue mass showed non-caseating granulomas consistent with sarcoidosis. Blood work showed a serum calcium of 11.1 mg/dL with an intact serum parathyroid hormone of 92 pg/dL. Primary hyperparathyroidism was suspected. A neck ultrasound and sestamibi parathyroid scintigraphy demonstrated a parathyroid nodule. She underwent surgical resection, and the histopathology revealed a parathyroid adenoma and non-caseating granulomata consistent with a diagnosis of sarcoidosis.

scholarly journals Features of infective native aortic aneurysms on computed tomography

2022 ◽  
Vol 13 (1) ◽  
Author(s):  
Warissara Jutidamrongphan ◽  
Boonprasit Kritpracha ◽  
Karl Sörelius ◽  
Keerati Hongsakul ◽  
Ruedeekorn Suwannanon
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Vena Cava ◽  
Psoas Muscle ◽  
Aortic Aneurysms ◽  
Rapid Expansion ◽  
Tissue Mass ◽  
Aortic Plaque ◽  
Fat Stranding ◽  
Thoracic And Abdominal

Abstract Background Infective native aortic aneurysm (INAA) is a rare clinical diagnosis. The purpose of this study was to describe the CT findings of INAAs in detail. Methods This was a retrospective single-center study of INAA patients at a major referral hospital between 2005 and 2020. All images were reviewed according to a protocol consisting of aneurysm features, periaortic findings, and associated surrounding structures. Results One hundred and fourteen patients (mean age, 66 years [standard deviation, 11 years]; 91 men) with 132 aneurysms were included. The most common locations were infrarenal (50.8%), aortoiliac (15.2%), and juxtarenal (12.9%). The mean transaxial diameter was 6.2 cm. Most INAAs were saccular (87.9%) and multilobulated (91.7%). Calcified aortic plaque was present in 93.2% and within the aneurysm in 51.5%. INAA instability was classified as contained rupture (27.3%), impending rupture (26.5%), and free rupture (3.8%). Rapid expansion was demonstrated in 13 of 14 (92.9%) aneurysms with sequential CT studies. Periaortic inflammation was demonstrated as periaortic enhancement (94.7%), fat stranding (93.9%), soft-tissue mass (92.4%), and lymphadenopathy (62.1%). Surrounding involvement included psoas muscle (17.8%), spondylitis (11.4%), and perinephric region (2.8%). Twelve patients demonstrated thoracic and abdominal INAA complications: fistulas to the esophagus (20%), bronchus (16%), bowel (1.9%), and inferior vena cava (IVC) (0.9%). Conclusion The most common CT features of INAA were saccular aneurysm, multilobulation, and calcified plaques. The most frequent periaortic findings were enhancement, fat stranding, and soft-tissue mass. Surrounding involvement, including psoas muscle, IVC, gastrointestinal tract, and bronchi, was infrequent but may develop as critical INAA complications.

Vulval myxoid liposarcoma

2001 ◽  
Vol 11 (4) ◽  
pp. 321-322 ◽  
Author(s):  
R. Donnellan ◽  
M. Moodley
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissue ◽  
Lymph Nodes ◽  
Soft Tissue Mass ◽  
Myxoid Liposarcoma ◽  
Complete Resection ◽  
Tissue Mass ◽  
History Of ◽  
Labium Majus ◽  
Draining Lymph Nodes

Abstract.Donnellan R, Moodley M. Vulval myxoid liposarcoma.A 26 year old woman presented with a 4-year history of a gradually enlarging fluctuant mass on the left labium majus. Histologic examination following excision revealed myxoid liposarcoma. Following the diagnosis, further surgery was performed to ensure complete resection. Routine excision of draining lymph nodes is not advocated. Although rare, myxoid liposarcoma should be considered in the differential diagnosis of a vulval soft tissue mass.

Unusual cause of a painless soft tissue mass of the scalp: a rare presentation of primary intracranial neuroendocrine neoplasm

2021 ◽  
Vol 14 (2) ◽  
pp. e236856
Author(s):  
Susruta Manivannan ◽  
Feras Sharouf ◽  
George Lammie ◽  
Paul Leach
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Neuroendocrine Tumour ◽  
Clinical Findings ◽  
Neuroendocrine Neoplasm ◽  
Tumour Resection ◽  
Rare Presentation ◽  
Tissue Mass ◽  
Left Hand ◽  
History Of

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.

High grade non-germinal centre-like diffuse large B-cell lymphoma double expressor presenting as a hydrocoele

2021 ◽  
Vol 14 (12) ◽  
pp. e247381
Author(s):  
Donnacha Hogan ◽  
Brian Hayes ◽  
Clodagh Keohane ◽  
Derek Barrry Hennessey
Keyword(s):  
Soft Tissue ◽  
B Cell ◽  
Multidisciplinary Team ◽  
Cell Lymphoma ◽  
Soft Tissue Mass ◽  
B Cell Lymphoma ◽  
Preoperative Imaging ◽  
Tissue Mass ◽  
Large B Cell Lymphoma ◽  
Large B Cell

A 72-year-old man was referred to our urology outpatient department with a left hemi-scrotal swelling increasing in size over a matter of weeks, initially suspicious for a left hydrocoele. Initial investigation with ultrasound (US) identified a heterogenous enlargement of the left testis and epididymis with a soft tissue mass extending through the inguinal canal. Subsequent CT detected this soft tissue mass to extend along the left gonadal vein to the level of the left renal vein. A biopsy of the retroperitoneal mass confirmed a diagnosis of diffuse large B-cell lymphoma. Immunohistochemical staining further categorised this lymphoma as double expressor but not double hit.Through multidisciplinary team involvement the patient was treated with combination steroids and chemotherapy. Given the scrotal involvement this was considered a sanctuary site for chemotherapy therefore the patient also received radiotherapy to the scrotum. He recovered well following his treatment. This case highlights how early specialist referral can identify rare variants of disease. Essential preoperative imaging with US prior to treating a presumed hydrocoele prevented inappropriate surgical excision. A multidisciplinary team approach improved the patient’s outcome and is hoped to have improved his chances of recurrence-free survival.

Schwannoma with Psammoma Body

2021 ◽  
Vol 111 (1) ◽  
Author(s):  
Lindsay M. Hummel ◽  
Susan Gamble ◽  
Robert Krouse ◽  
Darshana Jhala ◽  
Sharvari Dalal ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Carney Complex ◽  
Psammoma Body ◽  
Psammoma Bodies ◽  
Tissue Mass ◽  
Pathologic Evaluation ◽  
History Of ◽  
Male Veteran

We present a case of a 59-year-old male veteran with a chronic history of right foot soft-tissue mass that was causing pain in his shoes, but not functional or neurologic symptoms. Excision of the mass and pathologic evaluation resulted in multidisciplinary involvement and evaluation. In this example, the mass was found to be either an unusual schwannoma that happens to be psammoma body–rich or an unusual psammomatous melanocytic schwannoma that deviates from conventional examples, as a diagnostic consensus was unable to be reached. Schwannomas are an uncommon finding in the foot, and even more uncommon are those that contain psammoma bodies. Although rare, these tumors can be concerning for more systemic, life-altering diseases such as Carney complex, for which our patient refused genetic testing.

Osteoblastoma of the Foot and Ankle

1998 ◽  
Vol 19 (10) ◽  
pp. 698-704 ◽  
Author(s):  
H. Thomas Temple ◽  
Mark S. Mizel ◽  
Mark D. Murphey ◽  
Donald E. Sweet
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Mass ◽  
Armed Forces ◽  
Foot And Ankle ◽  
Common Site ◽  
Tissue Mass ◽  
Male Predominance ◽  
The Third ◽  
History Of ◽  
The Mean

A total of 329 patients with osteoblastoma were retrospectively reviewed from the archives of the Armed Forces Institute of Pathology, of which 41 (12.5%) presented with tumors in the foot and ankle. This was the third most common site of disease after the spine and femur. Overall, the mean age was 22.5 years, which was the same for the foot and ankle subset of patients; however, there was a significant male predominance in foot and ankle patients compared with the whole group. The majority of patients were skeletally mature (85.4%). Clinically, most patients presented with pain (97.2%), although one-third of the total related a history of antecedent trauma. The interval between the onset of symptoms and biopsy was 84 days (range, 0–572 days). Radiographically, the majority of lesions were in the hindfoot (N = 18; 44%) of which 16 of 18 tumors (89%) were in the talus. Of these, one-half were subperiosteal and dorsally based and were associated with osseous tumor matrix and a soft tissue mass. Two osteoblastomas, both in the metatarsals, transitioned into sarcomas; the rest were histologically benign. For diagnostic purposes, it was essential to obtain clinical, radiographic, and histologic correlation.

scholarly journals Perforating Rheumatoid Nodule Mimicking Malignant Soft-tissue Mass of the Forearm

2021 ◽  
pp. jrheum.201290
Author(s):  
Paul Ornetti ◽  
David Guillier ◽  
Geraldine Jeudy
Keyword(s):  
Rheumatoid Arthritis ◽  
Soft Tissue ◽  
Disease Activity ◽  
Rheumatoid Factor ◽  
Soft Tissue Mass ◽  
High Disease Activity ◽  
Rheumatoid Nodule ◽  
Tissue Mass ◽  
History Of ◽  
Malignant Soft Tissue

Rheumatoid nodule1, one of the most characteristic manifestations of rheumatoid arthritis (RA), occurs in approximately 30% of patients, is generally associated with positive rheumatoid factor, smoking, and high disease activity2, and occurs in some patients with specific genotypes receiving methotrexate (MTX)3. An 83-year-old woman with a history of anticitrullinated protein antibody–positive RA treated by oral MTX, as well as gout, was hospitalized for a growing tumor of her right forearm.

scholarly journals A case of retroperitoneal fibrosis secondary to chronic periaortitis

2019 ◽  
Vol 5 (3) ◽  
pp. 20190011
Author(s):  
Mariam A. Omar ◽  
Naushad Hassan Karim ◽  
Saeed samnakay
Keyword(s):  
Renal Failure ◽  
Soft Tissue ◽  
Ureteral Obstruction ◽  
Retroperitoneal Fibrosis ◽  
Soft Tissue Mass ◽  
Inflammatory Disorder ◽  
Infrarenal Aorta ◽  
Tissue Mass ◽  
History Of ◽  
Initial Imaging

Retroperitoneal fibrosis is a rare inflammatory disorder causing increased fibrotic deposition in the retroperitoneum, often leading to ureteral obstruction. We present a case report of a 33-year-old male with 2-month history of back pain. Initial imaging showed thickening around the infrarenal aorta. Six months later the patient presented with renal failure; a CT abdomen revealed extensive soft tissue mass around the aorta resulting in ureteral obstruction. Histology results of biopsy of the soft tissue mass revealed retroperitoneal fibrosis. It is important for clinicians to treat periaortitis early as this can prevent progression to retroperitoneal fibrosis which can cause severe secondary complications such as renal failure from ureteral obstruction.

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