Simultaneous double laryngeal tumours: a diagnostic and therapeutic challenge

2021 ◽  
Vol 14 (2) ◽  
pp. e239797
Author(s):  
Fergus Cooper ◽  
Rafael Moleron ◽  
Andrea Chapman ◽  
Muhammad Shakeel
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Soft Tissue ◽  
Histological Analysis ◽  
Primary Tumour ◽  
Second Primary ◽  
Soft Tissue Tumours ◽  
Rare Presentation ◽  
Laryngeal Tumours ◽  
Second Primary Tumour

Leiomyosarcomas are soft tissue tumours that rarely occur in the larynx. This case report describes the presentation and management of a 77-year-old man referred to the otolaryngology clinic with hoarseness who was found to have a large supraglottic leiomyosarcoma after panendoscopy and biopsies. He subsequently underwent laryngectomy for treatment of this tumour but, unexpectedly, the histological analysis of the laryngectomy specimen revealed a second primary tumour in the larynx—a squamous cell carcinoma (SCC). The patient had further treatment with neck radiotherapy. Three years after treatment, there are no signs of recurrence of either tumour. This case report discusses the very few similar cases of leiomyosarcoma coexisting with SCC in the larynx, collating the evidence surrounding the treatment of this rare presentation.

Foreign body reaction mimicking a second primary tumour of the oesophagus

2007 ◽  
Vol 122 (12) ◽  
pp. 1401-1403 ◽  
Author(s):  
J Pollock ◽  
N Beasley
Keyword(s):  
Case Report ◽  
Foreign Body ◽  
World Literature ◽  
Foreign Body Reaction ◽  
Primary Tumour ◽  
Anterolateral Thigh Flap ◽  
Second Primary ◽  
The World ◽  
Diagnostic Confusion ◽  
Second Primary Tumour

AbstractObjective:To present a significant complication of pharyngolaryngeal reconstruction, which resulted in diagnostic confusion as it mimicked a second primary tumour of the head and neck.Methods:Case report and review of the world literature.Case report:A 61-year-old man developed a granulomatous foreign body reaction, mimicking a second primary tumour, at the distal end of a salivary bypass tube, following pharyngolaryngectomy and reconstruction using a tubed anterolateral thigh flap. Clinically and radiologically, this was felt to represent a second primary tumour of the oesophagus, but biopsies revealed full thickness inflammation of the mucosa and granulation tissue. Repeat oesophagoscopy two weeks after removal of the tube showed complete resolution.Conclusion:No record of an oesophageal foreign body reaction to a Montgomery salivary bypass tube has previously been reported in the world literature. This report highlights the potential for such a lesion to cause diagnostic confusion with a second primary tumour.

scholarly journals Synchronous Buccal Carcinoma and Laryngeal Carcinoma- A Rare Presentation

2020 ◽  
Vol 28 (2) ◽  
pp. 182-186
Author(s):  
Ishita Sen ◽  
Debangshu Ghosh ◽  
Goutam Guha
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Buccal Mucosa ◽  
Primary Tumour ◽  
Second Primary ◽  
Glottic Carcinoma ◽  
Second Primary Malignancy ◽  
Primary Malignancy ◽  
Rare Presentation

Introduction Second primary malignancy as squamous cell carcinoma of larynx is rare after squamous cell carcinoma of buccal mucosa. Case Report A 47 year old male patient presented with a painless, progressive ulcer of left buccal mucosa near the angle of mouth for the last 3 months who also developed alteration in the quality of voice and respiratory distress 2 months later. On biopsy buccal lesion came out to be moderately differentiated squamous cell carcinoma. Direct laryngoscopy revealed a glottic growth and guided biopsy from the lesion revealed well differentiated keratinising squamous cell carcinoma which was managed successfully by total laryngectomy and buccal carcinoma by wide local excision followed by primary closure and supraomohyoid neck dissection in the same sitting. Discussion Having both index primary tumour and second primary tumour in head and neck region is a rare occurrence more so glottic carcinoma occurring synchronously with buccal carcinomas. Surgery is the mainstay of treatment in both the conditions.

A role for panendoscopy? Second primary tumour in early stage squamous cell carcinoma of the oral tongue

2015 ◽  
Vol 129 (S1) ◽  
pp. S27-S31 ◽  
Author(s):  
K Koo ◽  
R Harris ◽  
D Wiesenfeld ◽  
T A Iseli
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Primary Tumour ◽  
Second Primary ◽  
Oral Tongue ◽  
Second Primary Tumour

AbstractBackground:Panendoscopy is routinely used for the identification of occult second primary tumours in head and neck squamous cell carcinoma. However, its role in low risk subgroups, particularly non-smoking, non-drinking patients and patients presenting with early stage oral cavity lesions, is debatable.Methods:The records of 112 patients with T1 or T2 oral tongue squamous cell carcinoma were retrospectively reviewed. Demographic, disease characteristics and survival data were collected.Results:Average follow-up duration was 71.7 months (range, 3.6–238.3 months). Thirty-five patients died within this period. Thirteen second primary events were identified in 11 patients, with all but 2 tumours in the oral cavity or oropharynx. There was a single synchronous primary – a lung adenocarcinoma; all other events were metachronous. No non-smoking, non-drinking patients re-presented with a second primary tumour; tobacco and alcohol use are clearly risk factors for development of a second primary tumour.Conclusion:The role of panendoscopy for identifying synchronous primary tumours in patients with early stage oral tongue squamous cell carcinoma should be re-evaluated, particularly in non-smoking, non-drinking patients who are at low risk of second primary development. Close follow up with regular clinical examination including flexible fibre-optic endoscopy may be sufficient in this subgroup.

scholarly journals A Solitary Ventral Scapular Osteochondroma causing Pseudo-winging of Scapula: A Case Report

2021 ◽  
Vol 11 (7) ◽  
Author(s):  
Eknath Pawar ◽  
Nihar Modi ◽  
Amit Kumar Yadav ◽  
Jayesh Mhatre ◽  
Sachin Khemkar ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Soft Tissue ◽  
Young Child ◽  
Chest Wall ◽  
Rare Case ◽  
Rare Presentation ◽  
Medial Border ◽  
Soft Tissue Masses ◽  
Scapular Region

Introduction: Winging of scapula is defined as a failure of dynamic stabilizing structures that anchor the scapula to the chest wall, leading to prominence of the medial border of scapula. It could be primary, secondary, or voluntary. Primary winging could be true winging due to neuromuscular causes or pseudo-winging due to osseous or soft-tissue masses. A scapular osteochondroma is a very rare presentation site and causes pseudo-winging leading to pushing away of the scapula away from the chest wall presenting as medial border prominence. Here, we are reporting a rare case of a scapular osteochondroma causing a pseudo-winging of the scapula. Case Report: A 2-year-old male child presented with painless, immobile, and non-fluctuant swelling over the left scapular region, insidious in onset and progressive in nature. On examination, a non-tender, immobile swelling was palpable with a painless and unrestricted range of motion at the shoulder joint. After evaluating radiographs and CT scan, the patient was diagnosed to have a ventral scapular osteochondroma leading to pseudo-winging of the scapula. Conclusion: Despite the rarity, a differential diagnosis of a scapular osteochondroma should be kept in mind while examining a young child presenting with a winged scapula. Keywords: Scapula, osteochondroma, pseudo-winging.

PATIENT WITH SQUAMOUS CELL CARCINOMA AND SECOND PRIMARY TUMOR ON THE LIPS: A CASE REPORT

2020 ◽  
Vol 130 (3) ◽  
pp. e144
Author(s):  
ANTONIA TAIANE LOPES DE MORAES ◽  
YASMIM RODRIGUES SENA ◽  
KAROLYNY MARTINS BALBINOT ◽  
BEATRIZ VOSS MARTINS ◽  
SÂMIA CORDOVIL DE ALMEIDA
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumor ◽  
Second Primary ◽  
Second Primary Tumor

scholarly journals Increased risk of second primary tumours in patients with oesophageal squamous cell carcinoma: A nationwide study in a Western population

2020 ◽  
pp. 205064062097712
Author(s):  
Steffi EM van de Ven ◽  
Janne M Falger ◽  
Rob HA Verhoeven ◽  
Robert J Baatenburg de Jong ◽  
Manon CW Spaander ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Digestive Tract ◽  
Squamous Cell ◽  
Primary Tumour ◽  
Second Primary ◽  
Oesophageal Squamous Cell Carcinoma ◽  
Increased Risk ◽  
Second Primary Tumours ◽  
Multiple Primary

Background Patients with primary oesophageal squamous cell carcinoma are at risk of developing multiple primary tumours in the upper aero digestive tract. To date, most studies are performed in the Asian population. We aimed to evaluate the risk of multiple primary tumours in the upper aero digestive tract and stomach in patients with oesophageal squamous cell carcinoma in a Western population. Methods We performed a nationwide, retrospective cohort study in collaboration with the Netherlands Cancer Registry. Patients with primary oesophageal squamous cell carcinoma, diagnosed between 2000–2016, were included. Primary endpoints were synchronous and metachronous multiple primary tumour risk. Results The cohort consisted of 9058 patients, diagnosed with oesophageal squamous cell carcinoma (male: 57.3%, median age 67 years). In 476 patients (5.3%), 545 multiple primary tumours have been diagnosed. Most of them were located in the head and neck region (49.5%). Among all multiple primary tumours, 329 (60.4%) were diagnosed synchronously (<6 months after oesophageal squamous cell carcinoma diagnosis) and 216 (39.6%) metachronously (≥6 months). Patients with oesophageal squamous cell carcinoma had a significantly increased risk of both synchronous (standardised incidence ratio 10.95, 99% confidence interval 9.40–12.53) and metachronous multiple primary tumours (standardised incidence ratio 4.36, 99% confidence interval 3.56–5.10), compared to the general population. The median interval to metachronous second primary tumour diagnosis was 3.0 years (interquartile range 1.8–5.9). Conclusion Approximately one in 20 patients with primary oesophageal squamous cell carcinoma have a second primary tumour in the upper aero digestive tract or stomach, either at the time of oesophageal squamous cell carcinoma diagnosis or at a later stage. As second primary tumours occur at an increased risk compared to the general population, prospective studies are necessary to investigate the yield and survival benefit of screening for second primary tumours in patients with oesophageal squamous cell carcinoma.

scholarly journals Multiple Extramedullary Plasmacytoma with Lytic Bony Lesions: A Rare Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Akhlak Hussain ◽  
Mohinder Singh ◽  
Kuldip Singh ◽  
Harjot Bagga
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Soft Tissue ◽  
Subcutaneous Tissue ◽  
Extramedullary Plasmacytoma ◽  
Rare Presentation ◽  
Multiple Organs ◽  
Lytic Lesions ◽  
Rare Case Report ◽  
Bony Lesions

Objective. Multiple extramedullary plasmacytoma lesions involving subcutaneous tissue, breast, mediastinal tissue, spleen, and soft tissue of pelvic region along with multiple bones plasmacytomas without marrow plasmacytosis are a very rare presentation.Design. Case report.Result. A 54-year-old female was found to have multiple small bony lytic lesions, multiple extramedullary soft tissue plasmacytomas, serum M protein >3 g/dL, and elevated ESR. Bone marrow aspirate did not reveal any evidence of multiple myeloma/plasmacytosis. There was no anemia, hypercalcemia, or renal insufficiency.Conclusion. Extramedullary plasmacytoma can involve multiple organs at a time including bones and soft tissue without involving bone marrow.

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