scholarly journals Big-data and artificial-intelligence-assisted vault prediction and EVO-ICL size selection for myopia correction

2021 ◽  
pp. bjophthalmol-2021-319618
Author(s):  
Yang Shen ◽  
Lin Wang ◽  
Weijun Jian ◽  
Jianmin Shang ◽  
Xin Wang ◽  
...  

AimsTo predict the vault and the EVO-implantable collamer lens (ICL) size by artificial intelligence (AI) and big data analytics.MethodsSix thousand two hundred and ninety-seven eyes implanted with an ICL from 3536 patients were included. The vault values were measured by the anterior segment analyzer (Pentacam HR). Permutation importance and Impurity-based feature importance are used to investigate the importance between the vault and input parameters. Regression models and classification models are applied to predict the vault. The ICL size is set as the target of the prediction, and the vault and the other input features are set as the new inputs for the ICL size prediction. Data were collected from 2015 to 2020. Random Forest, Gradient Boosting and XGBoost were demonstrated satisfying accuracy and mean area under the curve (AUC) scores in vault predicting and ICL sizing.ResultsIn the prediction of the vault, the Random Forest has the best results in the regression model (R2=0.315), then follows the Gradient Boosting (R2=0.291) and XGBoost (R2=0.285). The maximum classification accuracy is 0.828 in Random Forest, and the mean AUC is 0.765. The Random Forest predicts the ICL size with an accuracy of 82.2% and the Gradient Boosting and XGBoost, which are also compatible with 81.5% and 81.8% accuracy, respectively.ConclusionsRandom Forest, Gradient Boosting and XGBoost models are applicable for vault predicting and ICL sizing. AI may assist ophthalmologists in improving ICL surgery safety, designing surgical strategies, and predicting clinical outcomes.

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Tahani Daghistani ◽  
Huda AlGhamdi ◽  
Riyad Alshammari ◽  
Raed H. AlHazme

AbstractOutpatients who fail to attend their appointments have a negative impact on the healthcare outcome. Thus, healthcare organizations facing new opportunities, one of them is to improve the quality of healthcare. The main challenges is predictive analysis using techniques capable of handle the huge data generated. We propose a big data framework for identifying subject outpatients’ no-show via feature engineering and machine learning (MLlib) in the Spark platform. This study evaluates the performance of five machine learning techniques, using the (2,011,813‬) outpatients’ visits data. Conducting several experiments and using different validation methods, the Gradient Boosting (GB) performed best, resulting in an increase of accuracy and ROC to 79% and 81%, respectively. In addition, we showed that exploring and evaluating the performance of the machine learning models using various evaluation methods is critical as the accuracy of prediction can significantly differ. The aim of this paper is exploring factors that affect no-show rate and can be used to formulate predictions using big data machine learning techniques.


Author(s):  
Vishal Babu Siramshetty ◽  
Dac-Trung Nguyen ◽  
Natalia J. Martinez ◽  
Anton Simeonov ◽  
Noel T. Southall ◽  
...  

The rise of novel artificial intelligence methods necessitates a comparison of this wave of new approaches with classical machine learning for a typical drug discovery project. Inhibition of the potassium ion channel, whose alpha subunit is encoded by human Ether-à-go-go-Related Gene (hERG), leads to prolonged QT interval of the cardiac action potential and is a significant safety pharmacology target for the development of new medicines. Several computational approaches have been employed to develop prediction models for assessment of hERG liabilities of small molecules including recent work using deep learning methods. Here we perform a comprehensive comparison of prediction models based on classical (random forests and gradient boosting) and modern (deep neural networks and recurrent neural networks) artificial intelligence methods. The training set (~9000 compounds) was compiled by integrating hERG bioactivity data from ChEMBL database with experimental data generated from an in-house, high-throughput thallium flux assay. We utilized different molecular descriptors including the latent descriptors, which are real-valued continuous vectors derived from chemical autoencoders trained on a large chemical space (> 1.5 million compounds). The models were prospectively validated on ~840 in-house compounds screened in the same thallium flux assay. The deep neural networks performed significantly better than the classical methods with the latent descriptors. The recurrent neural networks that operate on SMILES provided highest model sensitivity. The best models were merged into a consensus model that offered superior performance compared to reference models from academic and commercial domains. Further, we shed light on the potential of artificial intelligence methods to exploit the chemistry big data and generate novel chemical representations useful in predictive modeling and tailoring new chemical space.<br>


Author(s):  
Fernando Enrique Lopez Martinez ◽  
Edward Rolando Núñez-Valdez

IoT, big data, and artificial intelligence are currently three of the most relevant and trending pieces for innovation and predictive analysis in healthcare. Many healthcare organizations are already working on developing their own home-centric data collection networks and intelligent big data analytics systems based on machine-learning principles. The benefit of using IoT, big data, and artificial intelligence for community and population health is better health outcomes for the population and communities. The new generation of machine-learning algorithms can use large standardized data sets generated in healthcare to improve the effectiveness of public health interventions. A lot of these data come from sensors, devices, electronic health records (EHR), data generated by public health nurses, mobile data, social media, and the internet. This chapter shows a high-level implementation of a complete solution of IoT, big data, and machine learning implemented in the city of Cartagena, Colombia for hypertensive patients by using an eHealth sensor and Amazon Web Services components.


Author(s):  
Balamurugan Balusamy ◽  
Priya Jha ◽  
Tamizh Arasi ◽  
Malathi Velu

Big data analytics in recent years had developed lightning fast applications that deal with predictive analysis of huge volumes of data in domains of finance, health, weather, travel, marketing and more. Business analysts take their decisions using the statistical analysis of the available data pulled in from social media, user surveys, blogs and internet resources. Customer sentiment has to be taken into account for designing, launching and pricing a product to be inducted into the market and the emotions of the consumers changes and is influenced by several tangible and intangible factors. The possibility of using Big data analytics to present data in a quickly viewable format giving different perspectives of the same data is appreciated in the field of finance and health, where the advent of decision support system is possible in all aspects of their working. Cognitive computing and artificial intelligence are making big data analytical algorithms to think more on their own, leading to come out with Big data agents with their own functionalities.


2022 ◽  
pp. 406-428
Author(s):  
Lejla Banjanović-Mehmedović ◽  
Fahrudin Mehmedović

Intelligent manufacturing plays an important role in Industry 4.0. Key technologies such as artificial intelligence (AI), big data analytics (BDA), the internet of things (IoT), cyber-physical systems (CPSs), and cloud computing enable intelligent manufacturing systems (IMS). Artificial intelligence (AI) plays an essential role in IMS by providing typical features such as learning, reasoning, acting, modeling, intelligent interconnecting, and intelligent decision making. Artificial intelligence's impact on manufacturing is involved in Industry 4.0 through big data analytics, predictive maintenance, data-driven system modeling, control and optimization, human-robot collaboration, and smart machine communication. The recent advances in machine and deep learning algorithms combined with powerful computational hardware have opened new possibilities for technological progress in manufacturing, which led to improving and optimizing any business model.


Author(s):  
Zhaohao Sun ◽  
Andrew Stranieri

Intelligent analytics is an emerging paradigm in the age of big data, analytics, and artificial intelligence (AI). This chapter explores the nature of intelligent analytics. More specifically, this chapter identifies the foundations, cores, and applications of intelligent big data analytics based on the investigation into the state-of-the-art scholars' publications and market analysis of advanced analytics. Then it presents a workflow-based approach to big data analytics and technological foundations for intelligent big data analytics through examining intelligent big data analytics as an integration of AI and big data analytics. The chapter also presents a novel approach to extend intelligent big data analytics to intelligent analytics. The proposed approach in this chapter might facilitate research and development of intelligent analytics, big data analytics, business analytics, business intelligence, AI, and data science.


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