scholarly journals Long-term Anticoagulant Therapy for Coronary Thrombosis

BMJ ◽  
1958 ◽  
Vol 2 (5094) ◽  
pp. 473-475 ◽  
Author(s):  
M. Toohey
1959 ◽  
Vol 03 (02) ◽  
pp. 279-285 ◽  
Author(s):  
Marta Niewiarowska ◽  
Zenon Wegrzynowicz

SummaryThe influence of some coumarine derivatives (anticoagulant drugs: pelentan [tromexan], sintrom, marcoumar) on plasma fibrinolytic activity has been investigated. The cases studied included a number of patients with coronary thrombosis treated in long-term anticoagulant therapy and rabbits treated with a single dose of the drug.The anticoagulants have no significant effect either on fibrinogen or plasminogen level. All of the above mentioned drugs cause a prolongation of the euglobulin fibrinolysis time and an increase of the antiplasmin level. These two changes may be correlated to the prolongation of the prothrombin time.The authors suggest that the described phenomena may be useful for biological and clinical evaluation of anticoagulant drugs.


1979 ◽  
Vol 41 (01) ◽  
pp. 255-264 ◽  
Author(s):  
A. Barrillon ◽  
J. Kusmierek ◽  
A. Gerbaux

The results of post-mortem examination in 173 patients followed over an average period of five and a half years after their initial myocardial infarction are described. These 173 patients were divided into four groups according to whether or not they had received an oral anticoagulant and if so how adequately. An index of coronary and myocardial lesions was established for each heart. Recent occlusive coronary thromboses were four times less frequent in the group of patients who had received adequate anticoagulant therapy than in the other three groups of patients (p˂0,001). There was no significant difference between the inadequately treated groups and the untreated group. The recurrences of myocardial infarction were associated in 90 per cent of the cases with a recent occlusive thrombosis in the corresponding coronary artery and were found four times less frequently in the group subjected to effective long-term anticoagulant therapy (p˂0,001).


Author(s):  
Francisco J.A. Sanchez ◽  
Jose L.A. Martínez ◽  
Mirem A.U. Echezarreta ◽  
Ione V. Garcia ◽  
Jorge R. Alvaro

2008 ◽  
Vol 102 (12) ◽  
pp. 1618-1623 ◽  
Author(s):  
Roberta Rossini ◽  
Giuseppe Musumeci ◽  
Corrado Lettieri ◽  
Maria Molfese ◽  
Laurian Mihalcsik ◽  
...  

2016 ◽  
Vol 7 (1) ◽  
pp. 10 ◽  
Author(s):  
NervanaM. K Bayoumy ◽  
ShehanahFahad Al-Omair ◽  
NorahAhmed Musallam ◽  
NoraYazid Al-Deghaither ◽  
NoufAbdulwahab Al-Sadoun

Circulation ◽  
1961 ◽  
Vol 24 (3) ◽  
pp. 650-656
Author(s):  
WILIIAM R. TENCH ◽  
HUGH C. ROSS

1994 ◽  
Vol 1 (1) ◽  
pp. 17-25 ◽  
Author(s):  
Annette Lemche Gull�v ◽  
Birgitte Gade Koefoed ◽  
Palle Petersen

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