scholarly journals LUCSO-1—French pilot study of LUng Cancer Screening with low-dose computed tomography in a smokers population exposed to Occupational lung carcinogens: study protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. e025026
Author(s):  
Fleur Delva ◽  
François Laurent ◽  
Christophe Paris ◽  
Milia Belacel ◽  
Patrick Brochard ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
High Risk ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
Chest Ct ◽  
Risk Level ◽  
International Agency ◽  
Occupationally Exposed

IntroductionGuidelines concerning the follow-up of subjects occupationally exposed to lung carcinogens, published in France in 2015, recommended the setting up of a trial of low-dose chest CT lung cancer screening in subjects at high risk of lung cancer.ObjectiveTo evaluate the organisation of low-dose chest CT lung cancer screening in subjects occupationally exposed to lung carcinogens and at high risk of lung cancer.Methods and analysisThis trial will be conducted in eight French departments by six specialised reference centres (SRCs) in occupational health. In view of the exploratory nature of this trial, it is proposed to test initially the feasibility and acceptability over the first 2 years in only two SRCs then in four other SRCs to evaluate the organisation. The target population is current or former smokers with more than 30 pack-years (who have quit smoking for less than 15 years), currently or previously exposed to International Agency for Research on Cancer group 1 lung carcinogens, and between the ages of 55 and 74 years. The trial will be conducted in the following steps: (1) identification of subjects by a screening invitation letter; (2) evaluation of occupational exposure to lung carcinogens; (3) evaluation of the lung cancer risk level and verification of eligibility; (4) screening procedure: annual chest CT scans performed by specialised centres and (5) follow-up of CT scan abnormalities.Ethics and disseminationThis protocol study has been approved by the French Committee for the Protection of Persons. The results from this study will be submitted to peer-reviewed journals and reported at suitable national and international meetings.Trial registration numberNCT03562052; Pre-results.

Lung cancer screening in high-risk individuals with annual low-dose chest CT in a community setting.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. e12529-e12529
Author(s):  
Niraj K. Gupta ◽  
Richard K Freeman ◽  
Susan Storey ◽  
Dave Reeves ◽  
Anthony Ascioti ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
High Risk ◽  
Low Dose ◽  
Community Setting ◽  
Lung Cancer Screening ◽  
Chest Ct

scholarly journals Care Burden Derived from the Introduction of an Early Lung Cancer Screening Program in High-Risk HIV-Infected Patients

2019 ◽  
Vol 18 ◽  
pp. 232595821983907 ◽  
Author(s):  
Simona Cioaia ◽  
Carlos Tornero ◽  
Eugenio Sanchez ◽  
Mariajose Alos
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
High Risk ◽  
Low Dose ◽  
Screening Program ◽  
Lung Cancer Screening ◽  
Care Burden ◽  
Computed Tomographic ◽  
Cancer Screening Program ◽  
Lung Cancer Screening Program

We describe the care burden derived from a lung cancer screening program in high-risk patients with HIV. In a well-selected group with the described criteria, one annual low-dose thoracic computed tomographic exploration can be applied to 7.2% of the patients attended (95% confidence interval: 4.2-9.6), with at least one follow-up exploration in another 1.3%, with the generation of at least 2 extra visits for explanation of the protocol and results. If smoking habit does not change over the next 2 years, another 4.3% of the patients will have met the inclusion criteria. Early detection of lung cancer with low-dose thoracic computed tomographic could be of interest in HIV-infected patients because of the increased of risk but would imply an increase in care burden that must be taken into account.

Disparities in Follow-Up After Low-Dose Lung Cancer Screening

2020 ◽  
Vol 32 (4) ◽  
pp. 1058-1063 ◽  
Author(s):  
Joanna Sesti ◽  
Timothy J. Sikora ◽  
Dusty S. Turner ◽  
Amber L. Turner ◽  
Russell C. Langan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Low Dose ◽  
Lung Cancer Screening

Potential barriers to lung cancer screening in a minority population: Assessing attitudes, beliefs, and values towards screening with low-dose computed tomography amongst a high-risk minority population.

2021 ◽  
Vol 39 (28_suppl) ◽  
pp. 17-17
Author(s):  
Richard Stephen Sheppard ◽  
Stefani Beale ◽  
Janet Joseph ◽  
Sai Santhoshini Achi ◽  
Abosede Showunmi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
High Risk ◽  
Low Dose ◽  
Lung Cancer Screening ◽  
Minority Populations ◽  
Minority Population ◽  
Potential Barriers ◽  
Beliefs And Values ◽  
Low Dose Computed Tomography

17 Background: While the National Lung Screening Trial (NLST) has shown a relative reduction in mortality from lung cancer with the application of the United States Preventative Services Task Force (USPSTF) guidelines for the use of Low-Dose Computed Tomography (LDCT) in a select high risk population, many studies have shown that the rate of screening has been below the national average in minority population. Furthermore, lung cancer mortality still appears to be disproportionately higher amongst minority populations. With this study, we aim to evaluate the attitudes, beliefs and values towards lung cancer screening with LDCT in a predominantly Black and Hispanic population in our outpatient clinic. Methods: A survey was conducted over a 3-month period in our outpatient department at an urban inner-city safety net hospital. We included high risk smokers, aged 50 to 80 years who reported no evidence of symptoms. The survey consisted of 20 questions; these included utilizing the Health Belief Model to assess beliefs on perceived susceptibility, severity, benefits and barriers to screening, questions exploring fears of cancer screening and questions assessing overall willingness to undergo lung cancer screening with LDCT. We also included a question on the willingness of participants to engage in educational sessions with regards to lung cancer screening and risk reduction. Results were collected and analyzed via univariate logistic regression model to compare patient populations. Results: 67 patients participated in our survey. 62% were Black, 34% were Hispanic and 4% were Asian/Pacific Islanders. The mean age of our population was 64.5 years and they had an average of 27.2 pack-years of smoking. Issues related to insurance coverage and co-pay were identified as the most significant concern with regards to the unwillingness to undergo screening (p < 0.05). Other concerns identified were the fear of a positive screening result, fear of radiation exposure and lack of understanding of the association with smoking history and lung cancer (p = 0.12). All participants responded yes to being open to be educated on reducing their risk of lung cancer (p < 0.05). Conclusions: While many factors still exist with regards to lung cancer screening in minority populations, the cost of medical care, fear of radiation exposure and anxiety were identified as potential barriers to willingness to screen. Structured educational programs were identified as a possible measure that can be implemented to address these factors, with the potential to increase the willingness to undergo screening in a high risk minority population.

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