scholarly journals Transition in acquired brain injury youth (TrABI-Y): a systematic literature review protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e027384
Author(s):  
Jérôme Gauvin-Lepage ◽  
Julie Farthing ◽  
Shana Bissonnette ◽  
Louise Koclas ◽  
Magdalena Jaworski ◽  
...  

IntroductionAcquired brain injury (ABI) in paediatrics refers to children born with a neurological deficit, which will lead to a chronic neurological disorder. As advances in medical paediatric health progress, we are seeing these ABI youth transitioning into adult healthcare services while also going through different life events. Despite the growing number of young adult patients, access to transition programmes to facilitate the transition process is still limited and evidence on the effectiveness of these programmes is inconclusive. The purpose of this paper is to provide the protocol for an upcoming systematic literature review on this important issue.Methods and analysisThe start of this systematic literature review is planned for 1 October 2019 and will end on 31 December 2021. According to the PICO framework developed, the Population and the Problem of interest (P) will include children, adolescents and young adults (0–18 years) diagnosed with ABI. The selected articles will have to involve an Intervention (I) relating to the healthcare of this population or life transitions from paediatric to adult-oriented care. Studies will be included if a Comparator (C) intervention was used. The expected Outcomes (O) will have to report quantitative or qualitative health-related outcomes post-transition. This comprehensive search of peer-reviewed literature will include articles published between 2010 and 2020. The databases to be searched include Medline, All EBM Reviews, Embase, PsycINFO and CINAHL. The selected articles will be appraised using the Mixed Methods Appraisal Tool. A synthesis of the findings will be drafted to identify the effectiveness of available transition programmes as well as predictors, factors and determinants involved in the transition process.Ethics and disseminationThis project is not associated with direct individuals. The dissemination plan includes strategies such as using this systematic literature review to develop a research project on transition that will be published.

Author(s):  
Berje H. Shammassian ◽  
Andrew Ronald ◽  
Arvin Smith ◽  
Martha Sajatovic ◽  
Halinder Mangat ◽  
...  

2021 ◽  
Vol 8 (2) ◽  
pp. 36-45
Author(s):  
Christina Soeun Kwon ◽  
Patrick Daniele ◽  
Anna Forsythe ◽  
Christopher Ngai

Introduction: This systematic literature review analyzed published evidence on IgA nephropathy (IgAN), focusing on US epidemiology, health-related quality of life (HRQoL), and economic burden of illness. Methods: Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, Embase®, MEDLINE®, Cochrane, and Econlit (January 2010 to June 2020) were searched, along with relevant congresses (2017-2020). Results: Of 123 epidemiologic studies selected for data extraction, 24 reported IgAN diagnosis rates ranging from 6.3% to 29.7% among adult and pediatric patients undergoing renal biopsy, with all reported US rates <15%. No US studies reported IgAN prevalence. A meta-analysis of US studies calculated an annual incidence of 1.29/100 000 people, translating to an annual US incidence of 4236 adults and children. Relative to Europe, the United States had more patients diagnosed with IgAN in later chronic kidney disease stages. US rates of transition to end-stage renal disease (ESRD) ranged from 12.5% to 23% during 3-3.9 years of observation, rising to 53% during 19 years of observation. Across 8 studies reporting HRQoL, pain and fatigue were the most reported symptoms, and patients consistently ranked kidney function and mortality as the most important treatment outcomes. Patients with glomerulopathy reported worse mental health than healthy controls or hemodialysis patients; proteinuria was significantly associated with poorer HRQoL and depression. Conclusion: While economic evidence in IgAN remains sparse, management of ESRD is a major cost driver. IgAN is a rare disease where disease progression causes increasing patient burden, underscoring the need for therapies that prevent kidney function decline and HRQoL deterioration while reducing mortality.


2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Mohammad Reza Khajehaminian ◽  
Ali Ardalan ◽  
Sayed Mohsen Hosseini Boroujeni ◽  
Amir Nejati ◽  
Abbasali Keshtkar ◽  
...  

2020 ◽  
pp. bmjspcare-2020-002600
Author(s):  
Arjun Kingdon ◽  
Anna Spathis ◽  
Robert Brodrick ◽  
Gemma Clarke ◽  
Isla Kuhn ◽  
...  

BackgroundClinically assisted hydration (CAH) can be provided in the last days of life as drinking declines. The impact of this practice on quality of life or survival in the last days of life is unclear. Practice varies worldwide concerning this emotive issue.MethodSystematic literature review and narrative synthesis of studies evaluating the impact of, or attitudes toward, CAH in the last days of life. Databases were searched up to December 2019. Studies were included if the majority of participants were in the last 7 days of life, and were evaluated using Gough’s 'Weight of Evidence' framework. Review protocol registered with PROSPERO, registration number CRD42019125837.ResultsFifteen studies were included in the synthesis. None were judged to be both of high quality and relevance. No evidence was found that the provision of CAH has an impact on symptoms or survival. Patient and family carer attitudes toward assisted hydration were diverse.ConclusionThere is currently insufficient evidence to draw firm conclusions on the impact of CAH in the last days of life. Future research needs to focus on patients specifically in the last days of life, include those with non-malignant diagnoses, and evaluate best ways to communicate effectively about this complex topic with patients and their families.


2008 ◽  
Vol 30 (16) ◽  
pp. 1153-1176 ◽  
Author(s):  
Benjamin J. Turner ◽  
Jennifer M. Fleming ◽  
Tamara L. Ownsworth ◽  
Petrea L. Cornwell

2018 ◽  
Vol 33 (4) ◽  
pp. 383-406 ◽  
Author(s):  
Muhammad Ilyas ◽  
Waqas Ahmad ◽  
Hizbullah Khan ◽  
Saeeda Yousaf ◽  
Kifayatullah Khan ◽  
...  

Abstract Context Materials which exceed the balance of their production and destruction lead to the deterioration in the environment. Plastic is one such material which poses a big threat to the environment. A huge amount of plastic is produced and dumped into the environment which does not readily degrade naturally. In this paper, we address the organization of a large body of literature published on the management of waste plastics being the most challenging issue of the modern world. Objectives To address the issue of the management of waste plastics, there is a dire need to organize the literature published in this field. This paper presents a systematic literature review on plastic waste, its fate and biodegradation in the environment. The objective is to make conclusions on possible practical techniques to lessen the effects of plastic waste on the environment. Method A systematic literature review protocol was followed for conducting the present study [Kitchenham B, Brereton OP, Budgen D, Turner M, Bailey J, Linkman S. Systematic literature reviews in software engineering – A systematic literature review. Inf Softw Technol 2009;51(1):7–15.]. A predefined set of book sections, conference proceedings and high-quality journal publications during the years 1999 to September 2017 were used for data collection. Results One hundred and fifty-three primary studies are selected, based on predefined exclusion, inclusion and quality criteria. These studies will help to identify the fate of different waste plastics, their impact and management and the disposal techniques frequently used. The study also identifies a number of significant techniques and measures for the conversion of waste plastic materials into useful products. Conclusion Five fundamental strategies are used for the handling of plastic waste. These strategies include: recycling, depositing in landfill, incineration, microbial degradation and conversion into useful materials. All of these methods have their own limitations, due to which there is need to explore the studies for optimum solutions of the management of plastics waste.


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