scholarly journals Trends in symptomatology of thyroid malignancy in southern India and the efficacy of targeted fine needle aspiration cytology with ultrasonography guidance in diagnosis

2019 ◽  
Vol 6 (10) ◽  
pp. 3744
Author(s):  
C. Kiran Kailas ◽  
T. Nazareth Solomon ◽  
Punitha Thetraravu Oli ◽  
Sandeep Jose

Background: Thyroid cancers are on the rise all over the world. Studies have shown a tripling incidence of thyroid cancer in the United States in the past 35 years. Similar studies from Korea have also shown similar trends of 15 times increase in incidence. This study aims at assessing the recent trends in clinical presentation of thyroid malignancy and the efficacy of ultrasound targeted fine needle aspiration cytology (FNAC) in the diagnosis of thyroid malignancy.Methods: A cross sectional study was conducted involving 275 patients with thyroid disorders treated in the department of General Surgery at Dr. Somervell Memorial CSI Medical College, Trivandrum, India. Chi-square test was done for statistical test of significance and odds ratio for strength of association.Results: In this study group, 89% of the patients presented with swelling in front of the neck as chief complaint both in benign and malignancy. Swelling in front of the neck is the predominant symptom in thyroid malignancy. 52% of patients presented with the described symptoms of more than 6 months duration. The specificity of USG guided FNAC is 90% in diagnosing malignancy in goitre in this study group.Conclusions: The commonest symptom of thyroid malignancy was a painless swelling in the front of the neck. Most common thyroid pathology presenting as thyroid swelling was multinodular goitre. Nearly half of the patients presenting with symptoms more than 6 months had thyroid malignancy. FNAC under ultrasound guidance is an inexpensive accurate and practical investigation for evaluation of thyroid carcinomas.

2015 ◽  
Vol 59 (3) ◽  
pp. 253-257 ◽  
Author(s):  
José Eleutério Jr. ◽  
Alessa Aragão ◽  
Diane Isabelle Magno Cavalcante

Objective: We aimed to assess the cytological findings from fine-needle aspiration (FNA) of breast lesions with conventional smear (CS) and SurePath® (SP) cytology. Study Design: This was a cross-sectional study of women who underwent FNA from January 2012 to June 2013 for breast lesions with benign ultrasonography impressions in Fortaleza, Brazil. Two groups were formed. The first was composed of 102 samples subjected to CS and the second of 65 samples subjected to SP. The number of smears, the cellularity and the diagnostic hypotheses were compared. Fisher's exact tests with 95% confidence intervals were applied. Results: The women ranged in age from 22 to 75 years. SP cytology indicated greater cellularity than CS for the cystic lesions (p < 0.05). In the CS group, 72.5% of the samples required 3-4 slides, but in the SP group, only 9.2% required a second slide. The cellularity of the cystic samples was significantly greater with the SP method (p < 0.01). Conclusion: In FNA cytology of the breast, SP is a tool that is comparable to CS, but with the added benefits of better cellularity results for cystic lesions and requiring fewer slides for analysis.


2019 ◽  
Vol 29 (3) ◽  
Author(s):  
Mahdi Mohebbi ◽  
Mehrzad Gholampour Dehaki ◽  
Mahsa Mozaffari

The purpose of research was comparing the ultrasound (US) features and fine-needle aspiration cytology (FNAC) in detecting the thyroid nodules in clinical practice. A cross-sectional analytical study retrospectively reviewed the US and FNAC findings for a total of 170 thyroid nodules. The US features that we compared included echogenicity, calcifications, shape, halo and Doppler, between 2017 and 2018. Totally, 170 nodules of thyroid were studied, which contained 72 (42.4%) benign and 98 (57.6%) malignant thyroid nodules. The sonographic features were significantly associated with malignancy such as microcalcification (97.0%), hyperechogenicity (91.5%), wider than taller shape (98.0%), absent halo (90.9%) and positive Doppler (78.0%) (P < 0.01). The altogether accuracies of calcification, echogenicity, shape, halo, and Doppler were 0.96, 0.92, 0.97,0.82 and 0.82, respectively. Our data suggest that US features could be a good sonographic criterion for recommending FNA cytology with follow‐up thyroid sonography and FNA.


2011 ◽  
Vol 18 (03) ◽  
pp. 386-389
Author(s):  
SHER UZ ZAMAN BHATTI ◽  
SAIF UL MALOOK ◽  
M TARIQ ◽  
Ali Zulqurnain

Introduction: Goiter is a common problem in southern Punjab and thyroid surgery is frequently performed in surgical units of BVH Bahawalpur. Fine Needle Aspiration Cytology is the investigation of choice in detection of carcinoma thyroid. It is simple and quick to perform and can be readily repeated. Objectives: The aim of the study was to find out the diagnostic accuracy of FNAC in thyroid nodules. Study Design: Cross sectional study. Period: June 2009 to November 2009. Setting: Department of Surgery, BVH Bahawalpur. Methods: Fifty patients of goiter of age ranging from 16to60 years, irrespective of gender, presenting with a thyroid nodule and undergoing surgery were included in the study at Department of Surgery, BVH Bahawalpur. Information of each patient was collected on a structural Performa and then analyzed on SPSS to assess the sensitivity and specificity of the FNAC. Results: the sensitivity and specificity of FNAC was 72.2% and 97.8% respectively. Conclusions: FNAC should be performed in all cases of thyroid nodules because of its high sensitivity and specificity to diagnose the benign as well as the malignant lesions of thyroid.


Author(s):  
Mehnaz Choudhary ◽  
Rajat Gupta ◽  
Kuldeep Singh

Background: Intrathoracic and intra-abdominal tumors at inaccessible sites pose difficulty in diagnosis. Ultrasonography and computed tomography guided fine needle aspiration cytology has an important role in the diagnosis and distinguishing them as benign and malignant lesions. Image guided FNA has proved to be safe, quick, reliable and cost-effective method for obtaining tissue for cytopathological examination. The objective was to describe the pattern of intra-abdominal and intra thoracic masses on FNAC.Methods: This cross-sectional study was done in the postgraduate Department of pathology Government, Medical college Jammu i.e. 1st September 2017 to 30th September,2018 for a period of one year under image guided FNAC. Air dried and wet fixed smears were stained with may Grunwald Giemsa (MGG) and Papinacolau (PAP) stains respectively. Acid fast bacilli stain was done on additional smears in case of suspected tubercular lesions.Results: A total of 60 patients were subjected to ultrasonography and CT guided intra-abdominal and intra thoracic FNACs in a period of one year. FNAC was performed from various anatomical sites of which intra-abdominal lesions were 40 (liver:21 cases, gallbladder:8 cases, ovary: 3 cases, lymph nodes 3 cases, pancreas: 2 cases, omentum 2 cases, GIT 1 case).  Intrathoracic lesions were twenty (20); out of which lung cases were eighteen (18) and two (2) were mediastinal aspirations.Conclusions: Percutaneous fine needle aspiration cytology under image guidance well described the pattern of deep-seated lesions.


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