scholarly journals Interleukin-6 in the early assessment of acute pancreatitis.

Gut ◽  
1993 ◽  
Vol 34 (10) ◽  
pp. 1467-1467
Author(s):  
D D Tran
Keyword(s):  
Acute Pancreatitis ◽  
Interleukin 6 ◽  
Early Assessment

Serum interleukin-6, interleukin-8, andβ 2-Microglobulin in early assessment of severity of acute pancreatitis comparison with serum C-reactive protein

1995 ◽  
Vol 40 (11) ◽  
pp. 2341-2348 ◽  
Author(s):  
Raffaele Pezzilli ◽  
Paola Billi ◽  
Rita Miniero ◽  
Manuela Fiocchi ◽  
Onda Cappelletti ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Interleukin 6 ◽  
Interleukin 8 ◽  
C Reactive Protein ◽  
Early Assessment ◽  
Reactive Protein

INTERLEUKIN 6 AND CRP IN THE PREDICTION THE SEVERITY IN PATIENTS OF ACUTE PANCREATITIS

2015 ◽  
pp. 29-35
Author(s):  
Van Xung Nguyen ◽  
Van Huy Tran
Keyword(s):  
Acute Pancreatitis ◽  
Key Words ◽  
Interleukin 6 ◽  
Accuracy Rate ◽  
Background Data ◽  
Single Marker ◽  
Key Words Interleukin 6

Background: Data about the value of interleukin 6 and CRP in the prediction of severity of acute pancreatitis (AP) is still limited. This study is aimed at assessing the values of interleukin 6 and CRP in the prediction the severity of AP. Patients and methods: 55 patients with AP were enrolled. Interleukin was measured at 2 times: the 1st and the 3rd days. Results: IL-6 level day 1 in severe AP (168.86 ± 70.65 pg/ml) was significantly higher than in mild AP (89.54 ± 28.81 pg/ml) and IL-6 day 3 in severe AP (58.64 ± 20.77 pg/ml) significantly higher than mild AP (29.73 ± 14.88 pg/ml). concerning the prediction of severity of AP, IL-6 in day 1 (with cut-off 113.36 pg/ml) had the sensitivity 81.25% and the specificity 84.64%, PPV 68.4% and NPV 91.7%, accuracy rate 88.8%, AUC 0.888 and respectively in day 3 (with cut-off 41.38 pg/ml were 87.5%; 87.18%; 73.7%; 4.4%; 86.7%; 0.867. The values in prediction of severity were significantly higher when combining IL 6 and CRP in compare with the single marker. Conclusion: Combining Interleukin 6 and CRP may have a good value in the prediction of the severity of AP. Key words: Interleukin 6, CRP, acute pancreatitis, severity.

Advantages of Modified Computed Tomography Severity Index of Acute Pancreatitis Over Other Scoring System

KYAMC Journal ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 110-113
Author(s):  
Md Mofazzal Sharif ◽  
Khaleda Parvin Rekha ◽  
Umme Iffat Siddiqua ◽  
Mst Monira Khatun ◽  
AKM Enamul Haque ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Acute Pancreatitis ◽  
Clinical Outcome ◽  
Severe Disease ◽  
Severity Index ◽  
Observer Variation ◽  
Imaging Method ◽  
Close Monitoring ◽  
Early Assessment ◽  
Prompt Treatment

Pancreatitis is one of most complex and clinically challenging of all abdominal disorders. USG and abdominal Computed Tomography (CT) are the most commonly used diagnostic imaging modalities for the evaluation of pancreas. Computed Tomography (CT) is highly accurate and sensitive than USG in both diagnosing as well as demonstrating the extent. Early assessment of the cause and severity of acute pancreatitis is of utmost importance for prompt treatment and close monitoring of patient with severe disease. CT is the imaging method of choice for assessing the extent of acute pancreatitis and for evaluating complications. CT severity index is used to assess prognostic correlation and clinical outcome of acute pancreatitis. Modified CT severity index makes the score easier to calculate and reduces the inter-observer variation. KYAMC Journal Vol. 10, No.-2, July 2019, Page 110-113

scholarly journals Oxid Comparative Analysis of the Significance of BISAP and MEWS Score for an Early Assessment of Illness Severity and Treatment Outcome of Acute Pancreatitis

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Olivera Marinkovic ◽  
Slađana Trpkovic ◽  
Ana Sekulic ◽  
Aleksandra N. Ilic ◽  
Nataša Zdravkovc ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Intensive Care ◽  
Treatment Outcome ◽  
Prognostic Value ◽  
Fatal Outcome ◽  
High Specificity ◽  
Early Assessment ◽  
Time Points ◽  
Additional Costs ◽  
Vital Parameters

Abstract The aim of this study was to determine the significance of the use of the BISAP score, which is specific for patients with AP, in relation to the application of the MEWS score that is important for assessing the condition of critically ill patients in intensive care units, but is not specific for patients with AP. The research was conducted as a cohort prospective study and included patients of both sexes, older than 18 and diagnosed with AP. BISAP and MEWS score were monitored at least at four time points: on admission to the hospital (zero), 48 hours, 72 hours and 7 days after admission to the hospital. High levels of discrimination between patients with fatal outcome and cured patients are determined in both cases, with discrimination at MEWS being somewhat higher than BISAP score. The BISAP0 had the best discrimination for BISAP score, AUROC (0.807) and also MEWS0 for MEWS score, AUROC (0.899). In our research, the highest sensitivity was shown by BISAP7d (92.1%) and MEWS48 (88.1%), and a high specificity of 87.5% had BISAP score, 48h, 72h and MEWS score at all four points of measurement. BISAP score has a better prognostic value in relation to the form of pancreatitis, the development of complications and the outcome. However, the calculation of the MEWS score is based on monitoring the basic vital parameters so that its application is much simpler and does not require additional costs.

Comparison of scoring systems in early assessment of the severity of acute pancreatitis

Pancreatology ◽  
2016 ◽  
Vol 16 (3) ◽  
pp. S42
Author(s):  
Mihailo Bezmarevic ◽  
Darko Mirkovic
Keyword(s):  
Acute Pancreatitis ◽  
Scoring Systems ◽  
Early Assessment

Prognostic Value of CT in the Early Assessment of Patients with Acute Pancreatitis

2004 ◽  
Vol 182 (3) ◽  
pp. 569-574 ◽  
Author(s):  
J. Darío Casas ◽  
Rocío Díaz ◽  
Gracia Valderas ◽  
Antonio Mariscal ◽  
Patricia Cuadras
Keyword(s):  
Acute Pancreatitis ◽  
Prognostic Value ◽  
Early Assessment
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