scholarly journals P369 Incidence of vaginal infections in kenyan women randomized to continuous or cyclic contraceptive ring (CVR)

Author(s):  
Jeanne Marrazzo ◽  
Lei Wang ◽  
Nelly Mugo ◽  
Katherine Thomas ◽  
Kenneth Ngure ◽  
...  
2019 ◽  
Author(s):  
PEDRO ANTONIO REGIDOR ◽  
Manuela Sailer ◽  
Enrico Colli ◽  
Enrique Calvo ◽  
Santiago Palacios ◽  
...  

Abstract Background: To assess the menstrual cycle profile, tolerability, quality of life and sexual wellbeing in women using the vaginal contraceptive ring Ornibel®. Method: Non-interventional, retrospective, multi-center study on 103 women between 18 and 45 years old that used Ornibel® for at least 6 months. Menstrual cycle characteristics, vaginal infections and quality of life parameters were analyzed. Change in menstrual bleeding profiles and menstrual bleeding associated pain were assessed via visual analogue scales (VAS). Results: Menstrual flow and dysmenorrhea reduced significantly. The VAS score reductions were 16 and 22,5 points respectively (p < 0.001). No differences were observed between women that changed from another contraceptive method to the vaginal ring. The percentage of women without unscheduled bleedings or spotting increased from 79% to 88%. The percentage of women with unscheduled bleeding or spotting significantly decreased from 21% to 12%. Women rated the ring as very comfortable or comfortable (97%) as well as easy to insert (91%). The continuation of the usage of the ring and a recommendation for the ring were significantly associated with these two parameters. Conclusions: Ornibel® improved the menstrual cycle profile, reduced dysmenorrhea and shows a very high adherence to the use. Clinical trial register: DRKS-ID: DRKS00014982


GYNECOLOGY ◽  
2020 ◽  
Vol 22 (4) ◽  
pp. 28-32
Author(s):  
Valerii G. Volkov ◽  
Tatyana V. Zakharova

Relevance. Empirical treatment of vaginitis is indicated due to its polymicrobial etiology and limited microbiological analysis. The aim of the study was to study the combination of ornidazoleneomycinprednisoloneeconazole (ONPE, Elzhina) as a first-line drug for local treatment of patients with various forms of non-specific vaginitis. Materials and methods. The study included 55 non-pregnant women aged 18 to 50 years (381.5 years) who had clinical and laboratory signs of acute vaginitis. Results. All patients at the initial treatment complained of pathological discharge, 47 (85.5%) noted itching, burning, pain in the genital area of various degrees of severity, 17 (30.9%) discomfort when urinating, 9 (16.4%) unpleasant smell, 8 (14.5%) dyspareunia, 4 (2.2%) complained of sensations of a foreign body in the vagina. The clinical and laboratory effectiveness of treatment was 89.1% (49). In 6 (10.9%) patients, clinical improvement was noted, with the remaining laboratory signs of aerobic vaginitis. Conclusion. The new combination of ornidazoleneomycinprednisoloneeconazole (ONPE, Elzhina ) has a good efficacy and safety profile and can be used to initiate empirical treatment of non-specific inflammatory diseases of the lower genital tract.


GYNECOLOGY ◽  
2014 ◽  
Vol 16 (2) ◽  
pp. 9-13
Author(s):  
E.F. Kira ◽  
◽  
K.E. Semenova ◽  
A.M. Markarian ◽  
◽  
...  
Keyword(s):  

GYNECOLOGY ◽  
2017 ◽  
Vol 19 (6) ◽  
pp. 11-15 ◽  
Author(s):  
T E Karapetyan ◽  
V V Muravieva ◽  
A S Ankirskaya ◽  
L A Lyubasovskaya ◽  
T V Priputnevich

The aim of the study was to evaluate the effectiveness of treatment of women with opportunistic vaginal infections during pregnancy. Materials and methods. A prospective cohort study included 330 pregnant women, of whom 151 were diagnosed with bacterial vaginosis (BV), 37 had aerobic vaginitis (AB), 109 had vulvovaginal candidiasis (VC), 20 had a combination of VC + BV. When carrying out antibiotic therapy in the early stages of pregnancy, the principle of local treatment was observed. Results. Most often (46.0%), vaginal infections were detected when women were treated early in pregnancy. In the treatment of BV in the early stages of pregnancy with antiseptic chlorhexidine, a positive result of therapy was noted in 97.6% of women. Therapy with metronidazole or clindamycin BV in women who applied in the II and III trimesters, gave a positive result, respectively, in 90.0% and 89.5% of cases. The course of therapy with chlorhexidine pregnant women with AB was effective in 91.7% of cases with treatment in the first trimester and 92.0% in treatment in the II and III trimesters. In the treatment of VC in early pregnancy, natamycin was effective in 95.0% of women. In the II and III trimesters, econazole treatment was successful in 88.2% and 88.6%, respectively. In the treatment of combination of BV + VC in early gestation, the complex course of chlorhexidine + natamycin was effective in 76.5% of women, in II and III trimesters Neo-Penotran Forte was effective in 93.8% of pregnant women. Relapses of vaginal infections were observed in 34 pregnant women (10.3%). Superinfection with fungi was noted in 9.3% of cases of BV treatment and in 8.1% of pregnant women with AB. Among women observed from early pregnancy, there were no cases of premature birth, manifestations of intrauterine infections were noted in 5.3% of newborns. At treatment in the II and III trimesters, premature birth was in 6.5% and 13.5% of women, and manifestations of intrauterine infections - in 15.3% of newborns. Thus, microbiological monitoring of timely detection and treatment of opportunistic vaginal infections in pregnant at-risk groups showed the advisability of treating these infections in early gestation.


Author(s):  
Brooke Shannon

A social constructionist methodology was used to explore how Kenyan women university students interact with information in everyday life. Focus was on how participants interpret experiences within the historical, cultural, and material spaces they inhabit. Methods used were linguistics pragmatics, phenomenology, and hermeneutics. Conceptual implications for information literacy are discussed.Une méthodologie sociale constructioniste est utilisée pour explorer comment les étudiantes universitaires kenyanes interagissent avec l’information au quotidien. Nous avons insisté sur les façons dont les participantes interprètent leurs expériences dans les espaces historiques, culturels et matériels où elles habitent. Les méthodologies utilisées comprennent la pragmatique linguistique, la phénoménologie et l’herméneutique. Nous discutons finalement de leurs implications sur la maîtrise de l’information. 


Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 250
Author(s):  
Louise Witteman ◽  
Herman A. van Wietmarschen ◽  
Esther T. van der Werf

Due to the excessive use of antibiotic and antimycotic treatments, the risk of resistant microbes and fungi is rapidly emerging. Previous studies have demonstrated that many women with (recurrent) urinary tract infection (UTI) and/or vaginal infections (VIs) welcome alternative management approaches to reduce the use of antibiotics and antifungals and avoid short- and long-term adverse effects. This study aims to determine which complementary medicine (CM) and self-care strategies are being used by women suffering from (recurrent) UTI and VI in The Netherlands and how they perceive their effectiveness in order to define directions for future research on safety, cost-effectiveness, and implementation of best practices. A cross-sectional online survey was performed among women, ≥18 years old, with a history of UTIs; 162 respondents were included in the data analysis, with most participants aged between 50 and 64 years (36.4%). The women reported having consulted a CM practitioner for UTI-specific symptoms (23.5%) and VI-specific symptoms (13.6%). Consultations of homeopaths, acupuncturists, and herbal physicians are most often reported. Overall, 81.7% of the women suffering from UTI used complementary or self-care strategies besides regular treatment, and 68.7% reported using CM/self-care strategies to treat vaginal symptoms. UTI- related use of cranberries (51.9%), vitamin C (43.8%), and D-mannose (32.7%) were most reported. Perceived effectiveness was mostly reported for homeopathic remedies and D-mannose. The results showed a substantial burden of UTI and VI on daily and sexual activities. Besides the frequency of use, the indication of perceived effectiveness seems to be an important parameter for further and rigorously designed research to encourage nonantibiotic/antifungal treatment implementation into daily clinical practice.


2014 ◽  
Vol 20 (1) ◽  
pp. 101-129 ◽  
Author(s):  
Mwangi wa Gĩthĩnji ◽  
Charalampos Konstantinidis ◽  
Andrew Barenberg
Keyword(s):  

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