scholarly journals Early childhood infection and atopic disorder

Thorax ◽  
1998 ◽  
Vol 53 (11) ◽  
pp. 927-932 ◽  
Author(s):  
I S. Farooqi ◽  
J. M Hopkin
Keyword(s):  
Early Childhood ◽  
Atopic Disorder ◽  
Childhood Infection

scholarly journals Risk Factors for Early Childhood Infection of Human Herpesvirus-8 in Zambian Children: The Role of Early Childhood Feeding Practices

2013 ◽  
Vol 23 (2) ◽  
pp. 300-308 ◽  
Author(s):  
Kay L. Crabtree ◽  
Janet M. Wojcicki ◽  
Veenu Minhas ◽  
David R. Smith ◽  
Chipepo Kankasa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Childhood ◽  
Human Herpesvirus ◽  
Feeding Practices ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
Childhood Infection

scholarly journals Maternal Infection Is a Risk Factor for Early Childhood Infection in Filariasis

2015 ◽  
Vol 9 (7) ◽  
pp. e0003955 ◽  
Author(s):  
Madhusmita Bal ◽  
Prakash K. Sahu ◽  
Nityananda Mandal ◽  
Ashok K. Satapathy ◽  
Manoranjan Ranjit ◽  
...  
Keyword(s):  
Early Childhood ◽  
Risk Factor ◽  
Maternal Infection ◽  
Childhood Infection

scholarly journals Relationships Between Maternal Antibody Responses and Early Childhood Infection With Kaposi Sarcoma-Associated Herpesvirus

2020 ◽  
Vol 222 (10) ◽  
pp. 1723-1730
Author(s):  
Lisa K Poppe ◽  
Chipepo Kankasa ◽  
Charles Wood ◽  
John T West
Keyword(s):  
Immune Response ◽  
Early Childhood ◽  
Neutralizing Antibodies ◽  
Geometric Mean ◽  
Kaposi Sarcoma ◽  
Humoral Response ◽  
Maternal Immune Response ◽  
Potential Factors ◽  
Mother To Child ◽  
Childhood Infection

Abstract While mother-to-child transmission is believed to play in important role in early childhood infection with Kaposi sarcoma-associated herpesvirus (KSHV), the maternal immune response remains largely uncharacterized. This study aimed to characterize the longitudinal humoral response to KSHV in a cohort of HIV-infected Zambian mothers without KS and identify potential factors that may influence transmission. In total, 86/124 (69.4%) mothers were found to be KSHV seropositive. Longitudinal KSHV titers were fairly stable over time, although seroreversion was still common. Of the total 124 mothers, 81 had at least 1 child KSHV seroconvert during the 2 years analyzed, while the remaining 43 mothers had KSHV-seronegative children. Mothers of KSHV-negative children had higher geometric mean titers than mothers of KSHV-positive children; however, there was no difference in the presence of neutralizing antibodies. This suggests that a strong anti-KSHV immune response, and potentially nonneutralizing antibodies, may reduce transmission.

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