Isolation of Mycoplasma ovipneumoniae from sheep with chronic pneumonia

1975 ◽  
Vol 97 (11) ◽  
pp. 205-206 ◽  
Author(s):  
T. Staint George ◽  
L. Carmichael
Keyword(s):  
Chronic Pneumonia ◽  
Mycoplasma Ovipneumoniae

scholarly journals Strategies of Mycoplasma ovipneumoniae to evade immune clearance by alveolar macrophages

2021 ◽  
Author(s):  
Liyang Gao ◽  
Kai Zhang ◽  
Ying Zhang ◽  
Chunji Ma ◽  
Xiaoyu Zhou ◽  
...  
Keyword(s):  
Alveolar Macrophages ◽  
Healthy Adult ◽  
Protein Assay ◽  
Immune Clearance ◽  
Autophagy Pathway ◽  
Endosome Maturation ◽  
Related Proteins ◽  
Chronic Pneumonia ◽  
Lower Expression ◽  
Mycoplasma Ovipneumoniae

Evidences showed that M. ovipneumoniae might associate with the development and duration of chronic pneumonia. Moreover, sheep infected with M. ovipneumoniae are easily infected by other organisms, suggesting that M. ovipneumoniae may play an immunosuppressive role during infection. However, the mechanism is still poorly understood. The infection occurs in the airway, where resident alveolar macrophages first encounter M. ovipneumoniae. Therefore, primary alveolar macrophages (AMs) were collected from the lungs of healthy adult sheep, and the (iTRAQ) protein assay was used to investigate the immunosuppressive effects of M. ovipneumoniae on sheep AMs. The RAW264.7 cells were used to confirm the findings. The results showed that M. ovipneumoniae promoted higher expression of anti-apoptotic proteins and lower expression of apoptosis-related proteins in the infected AMs. Moreover, the number of infected AMs increased. However, M. ovipneumoniae reduced ATP levels in AMs and impaired late endosome maturation and phagolysosome fusion. Furthermore, M. ovipneumoniae inhibited the autophagy pathway via the Akt-mTOR axis in AMs. These findings indicated that M. ovipneumoniae had distinctive strategies to evade elimination caused by the AMs. The findings might explain the chronic infection and co-infection in sheep infected by M. ovipneumoniae.

PROBLEMS OF COMBINING TUBERCULOSIS OF THE RESPIRATORY ORGANS WITH CYSTIC FIBROSIS

2021 ◽  
pp. 28-31
Author(s):  
А.Г. ИСАЕВА ◽  
Л.Ш. КАСЕНОВА ◽  
Л.Д. БЕКЖАНОВА ◽  
А.М. АБДУКАЛЫКОВ ◽  
З.М. АТАШОВА ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Airway Obstruction ◽  
Lung Tissue ◽  
Clinical Symptoms ◽  
Lesion Area ◽  
Standard Mode ◽  
Chronic Pneumonia

Клиническая симптоматика туберкулеза в сочетании с муковисцидозом была обусловлена суммацией проявлений сочетанной патологии и протекала, как тяжелая хроническая пневмония, непрерывно рецидивирующая, с выраженным синдромом обструкции дыхательных путей. Туберкулезное воспаление характеризовалось большей площадью поражения, деструкцией легочной ткани и обнаружением микобактерий туберкулеза в мокроте. Независимо от наличия сопутствующей патологии применялась химиотерапия в стандартном режиме.Цель исследования: оценить течение заболевания и эффективность лечения туберкулезом органов дыхания с учетом наличия сопутствующих заболеваний. Clinical symptoms of tuberculosis in association with cystic fibrosis was determined by summation of the manifestations of comorbidity and proceeded as severe chronic pneumonia, recurrent continuously, with marked airway obstruction syndrome. Tuberculous inflammation was characterized by a larger lesion area, destruction of the lung tissue and the detection of MBT in sputum. Regardless of the presence of concomitant pathology, chemotherapy was used in standard mode.

Effect of Lactobacillus casei and Yogurt Administration on Prevention of Pseudomonas aeruginosa Infection in Young Mice

2001 ◽  
Vol 64 (11) ◽  
pp. 1768-1774 ◽  
Author(s):  
SUSANA ALVAREZ ◽  
CLAUDIA HERRERO ◽  
ELENA BRU ◽  
GABRIELA PERDIGON
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Oral Administration ◽  
Lactobacillus Casei ◽  
Opportunistic Pathogen ◽  
Lung Infection ◽  
Pseudomonas Aeruginosa Infection ◽  
Dose Dependent ◽  
Chronic Pneumonia ◽  
Dose Dependent Effect ◽  
Young Mice

Pseudomonas aeruginosa is an opportunistic pathogen that rarely causes pulmonary disease in normal hosts but one that is an important cause of acute pneumonia in immunocompromised patients, including neonates, and of chronic pneumonia in patients with cystic fibrosis. The aim of this work was to study the effect of oral administration of Lactobacillus casei and yogurt on prevention of P. aeruginosa lung infection in young mice (3 weeks old). This study demonstrates that oral administration of L. casei or yogurt to young mice enhanced lung clearance of P. aeruginosa and phagocytic activity of alveolar macrophages through a dose-dependent effect. There were, however, no significant differences in white blood cell (WBC) differential counts. Furthermore, it was observed that previous administration of L. casei or yogurt induced a significant increase in IgA and IgM levels in bronchoalveolar lavages (BALs) after a P. aeruginosa infection, although there was no relationship with the serum values.

scholarly journals Foreign bodies in the torax

2007 ◽  
Vol 64 (1) ◽  
pp. 61-63
Author(s):  
Zenaida Cerimagic ◽  
Safet Guska ◽  
Kenan Kadic ◽  
Bedrudin Banjanovic
Keyword(s):  
Case Report ◽  
Foreign Bodies ◽  
Lung Abscess ◽  
Thoracic Surgeon ◽  
Thoracic Drainage ◽  
Lung Injuries ◽  
Pulmonary Infiltration ◽  
One Year ◽  
Chronic Pneumonia

Background. Metallic foreign bodies in the lung could be recognized using radiography. Non-metallic foreign bodies make difficulties because they are not as dense as metals. The aim of this report was to present the case of nonmetallic foreign bodies in the lung. Case report. A soldier of the Federation Army of Bosnia and Hertzegovina, injured in the explosion in 1998 was presented. The soldier was subjected to thoracic drainage and surgery tretment of the wound. After one year, the pulmologist treated him with tuberculostatics because of hemoptysis and pulmonary infiltration shown by a radiogram. This therapy had no effects, and the pulmologist presented this case to the thoracic surgeon who made thoracotomy removing a piece of wood (13 ? 2 ? 0.7 cm), 20 different-size pieces of wood, and a piece of textile from the lung. Conclusion. Patients with penetrating explosive lung injuries without metallic foreign bodies shown by a radiogram, with complications as hemoptisis, lung abscess, bronchiectasis, obstruction of the bronchus, chronic pneumonia should be subjected to thoracotomy for removing suspected foreign bodies without resecting the lung.

Chronic Pneumonia

2020 ◽  
pp. 75-86
Author(s):  
Shravan Kumar Paswan ◽  
Vishal Kumar Vishwakarma ◽  
Chetan Rastogi ◽  
Pritt Verma ◽  
Ch. V. Rao ◽  
...  
Keyword(s):  
Chronic Pneumonia

scholarly journals Genome Sequence of Pseudomonas aeruginosa Strain AH16, Isolated from a Patient with Chronic Pneumonia in China

2012 ◽  
Vol 194 (21) ◽  
pp. 5976-5977 ◽  
Author(s):  
D.-Q. Wu ◽  
H. Cheng ◽  
C. Wang ◽  
C. Zhang ◽  
Y. Wang ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Genome Sequence ◽  
Chronic Pneumonia

scholarly journals Draft Genome Sequence of a New Zealand Isolate of Mycoplasma ovipneumoniae

2020 ◽  
Vol 9 (10) ◽  
Author(s):  
B. J. Bridgeman ◽  
S. K. Gupta ◽  
A. Murray ◽  
V. S. R. Dukkipati ◽  
E. Altermann ◽  
...  
Keyword(s):  
New Zealand ◽  
Genome Sequence ◽  
De Novo ◽  
Draft Genome ◽  
Illumina Miseq ◽  
Draft Genome Sequence ◽  
Content Type ◽  
Mycoplasma Ovipneumoniae

The genome of New Zealand Mycoplasma ovipneumoniae isolate 90 was sequenced and assembled using an Illumina MiSeq system and combining the built-in Geneious de novo and Velvet de novo assemblers. The 1,031,345-bp-long genome harbored 711 genes with a coding percentage of 86.6.

scholarly journals Comprehensive RNA-Seq profiling of the lung transcriptome of Argali hybrid sheep in response to experimental Mycoplasma ovipneumoniae infection

2020 ◽  
Vol 132 ◽  
pp. 57-68
Author(s):  
Zengqiang Li ◽  
Zhihui Du ◽  
Yanming Sun ◽  
Jixue Wang ◽  
Haiyan Liu ◽  
...  
Keyword(s):  
Rna Seq ◽  
Mycoplasma Ovipneumoniae
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