scholarly journals A comparison of the health benefits of reduced-exertion high-intensity interval training (REHIT) and moderate-intensity walking in type 2 diabetes patients

2017 ◽  
Vol 42 (2) ◽  
pp. 202-208 ◽  
Author(s):  
José S. Ruffino ◽  
Preeyaphorn Songsorn ◽  
Malindi Haggett ◽  
Daniel Edmonds ◽  
Anthony M. Robinson ◽  
...  

Reduced-exertion high-intensity interval training (REHIT) is a genuinely time-efficient intervention that can improve aerobic capacity and insulin sensitivity in sedentary individuals. The present study compared the effects of REHIT and moderate-intensity walking on health markers in patients with type 2 diabetes (T2D) in a counter-balanced crossover study. Sixteen men with T2D (mean ± SD age: 55 ± 5 years, body mass index: 30.6 ± 2.8 kg·m−2, maximal aerobic capacity: 27 ± 4 mL·kg−1·min−1) completed 8 weeks of REHIT (three 10-min low-intensity cycling sessions/week with two “all-out” 10–20-s sprints) and 8 weeks of moderate-intensity walking (five 30-min sessions/week at an intensity corresponding to 40%–55% of heart-rate reserve), with a 2-month wash-out period between interventions. Before and after each intervention, participants underwent an incremental fitness test, an oral glucose tolerance test (OGTT), a whole-body dual-energy X-ray absorptiometry scan, and continuous glucose monitoring. REHIT was associated with a significantly larger increase in maximal aerobic capacity compared with walking (7% vs. 1%; time × intervention interaction effect: p < 0.05). Both REHIT and walking decreased resting mean arterial pressure (−4%; main effect of time: p < 0.05) and plasma fructosamine (−5%; main effect of time: p < 0.05). Neither intervention significantly improved OGTT-derived measures of insulin sensitivity, glycaemic control measured using continuous glucose monitors, blood lipid profile, or body composition. We conclude that REHIT is superior to a 5-fold larger volume of moderate-intensity walking in improving aerobic fitness, but similar to walking REHIT is not an effective intervention for improving insulin sensitivity or glycaemic control in T2D patients in the short term.

Author(s):  
Xiaochen Liu ◽  
Gaifeng Wang

Abstract Background Exercise benefits people with abnormal glucose metabolism, and serum ficolin-3 levels have been reported to be associated with diabetes. However, no relevant study has discussed the relationship between high-intensity interval training (HIIT) and ficolin-3 in a Chinese population. Objective To compare the effect of HIIT and moderate-intensity continuous training (MICT) on blood pressure, glucose control, the lipid profile and the serum ficolin-3 level in patients with prediabetes and type 2 diabetes (T2D). Methods We recruited 145 patients with prediabetes and 196 T2D patients from March to June 2018. All participants were randomly grouped into HIIT and MICT groups. HIIT consisted of progressing to twelve 1-min bouts at 90% maximal aerobic capacity (1 min recovery), and MICT consisted of progressing to 20 min at 65% maximal aerobic capacity. ˙VO2peak, body composition, blood pressure, glucose, the lipid profile and the serum ficolin-3 level were measured before and after three weeks of training. Results After 3 weeks of training, participants in both the HIIT and MICT groups had significantly lower SBP, BMI, waist circumference, % body fat, and serum levels of FPG, TC, TGs, UA and ficolin-3, as well as increased vital capacity and VOmax. Additionally, the patients in the HIIT group still had significantly lower levels of 2hPG and LDL-C, regardless of prediabetes or diabetes status. After comparing the differences in the variation in parameters between the HIIT and MICT groups, we found that HIIT could help patients with prediabetes or diabetes acquire better effects of treatment in regard to anthropometry, blood pressure, glucose control, UA and ficolin-3 levels than MICT. Finally, the patients in the HIIT group had a lower rate of loss to follow-up and a higher rate of session attendance. Conclusions Both HIIT and MICT were beneficial exercise strategies for health in patients with prediabetes or T2D. However, HIIT is a more time-efficient strategy and could lower the serum level of ficolin-3 in patients after 3 weeks of training.


Biology ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 66
Author(s):  
Lucas Raphael Bento Silva ◽  
Paulo Gentil ◽  
Camila Simões Seguro ◽  
Jordana Campos Martins de Oliveira ◽  
Maria Sebastiana Silva ◽  
...  

Different exercise models have been used in patients with type 2 diabetes mellitus (T2D), like moderate intensity continuous training (MICT) and high intensity interval training (HIIT); however, their effects on autonomic modulation are unknown. The present study aimed to compare the effects of different exercise modes on autonomic modulation in patients with T2D. In total, 44 adults with >5 years of T2D diagnosis were recruited and stratified into three groups: HIIT-30:30 (n = 15, age 59.13 ± 5.57 years) that performed 20 repetitions of 30 s at 100% of VO2peak with passive recovery, HIIT-2:2 (n = 14, age 61.20 ± 2.88) that performed 5 repetitions of 2 min at 100% of VO2peak with passive recovery, and MICT (n = 15, age 58.50 ± 5.26) that performed 14 min of continuous exercise at 70% of VO2peak. All participants underwent anamnesis and evaluation of cardiorespiratory fitness and cardiac autonomic modulation. All protocols were equated by total distance and were performed two times per week for 8 weeks. Group × time interactions were observed for resting heart rate (HRrest) [F(2.82) = 3.641; p = 0.031] and SDNN [F(2.82) = 3.462; p = 0.036]. Only the HIIT-30:30 group significantly reduced SDNN (p = 0.002 and 0.025, respectively). HRrest reduced more in the HIIT-30:30 group compared with the MICT group (p = 0.038). Group × time interactions were also observed for offTAU [F(2.82) = 3.146; p = 0.048] and offTMR [F(2.82) = 4.424; p = 0.015]. The MICT group presented increased values of offTAU compared with the HIIT-30:30 and HIIT-2:2 groups (p = 0.001 and 0.013, respectively), representing a slower HR response after eight weeks of intervention. HIIT, specially HIIT-30:30, represents a promising measure for improving autonomic modulation in patients with T2D.


2016 ◽  
Vol 41 (11) ◽  
pp. 1117-1123 ◽  
Author(s):  
Richard S. Metcalfe ◽  
Nicolas Tardif ◽  
Dylan Thompson ◽  
Niels B.J. Vollaard

Previously it has been reported that reduced-exertion high-intensity interval training (REHIT; total training time of 3 × 10 min per week) improves maximal aerobic capacity in both sedentary men and women, but improves insulin sensitivity in men only. The aim of the present study was to determine whether there is a true sex difference in response to REHIT, or that these findings can be explained by the large interindividual variability in response inherent to all exercise training. Thirty-five sedentary participants (18 women; mean ± SD age for men and women, respectively: age, 33 ± 9 and 36 ± 9 years; body mass index, 25.1 ± 2.1 and 24.1 ± 3.5 kg·m−2; maximal aerobic capacity, 38.6 ± 8.3 and 31.6 ± 4.6 mL·kg−1·min−1) completed a 6-week REHIT programme consisting of eighteen 10-min unloaded cycling sessions with 1 (first session) or 2 (all other sessions) “all-out” 10–20-s sprints against a resistance of 5% of body mass. Maximal aerobic capacity and oral glucose tolerance test-derived insulin sensitivity were determined before and after training. REHIT was associated with an increase in maximal aerobic capacity (2.54 ± 0.65 vs. 2.78 ± 0.68 L·min−1, main effect of time: p < 0.01), a trend toward reduced plasma insulin area-under-the-curve (AUC; 6.7 ± 4.8 vs. 6.1 ± 4.0 IU·min−1·mL−1, p = 0.096), but no significant change in plasma glucose AUC or the Cederholm index of insulin sensitivity. Substantial interindividual variability in response to REHIT was observed for all variables, but there was no significant effect of sex. In conclusion, REHIT improves the key health marker of aerobic capacity within a minimal total training time-commitment. There is large interindividual variability in responses to REHIT, but sex differences in the responses are not apparent.


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