scholarly journals INTEGRATING COMPUTATION AND VISUALIZATION FOR BIOMOLECULAR ANALYSIS: AN EXAMPLE USING PYTHON AND AVS

Author(s):  
M. F SANNER ◽  
B. S. DUNCAN ◽  
C. J.CARRILLO ◽  
A. J. OLSON
2002 ◽  
Author(s):  
Min Yue ◽  
Katherine Dunphy ◽  
Jerry Jenkins ◽  
Christopher Dames ◽  
Guanghua Wu ◽  
...  

2021 ◽  
Vol 25 (1) ◽  
pp. 21-34
Author(s):  
Rafael B. Pereira ◽  
Alexandre Plastino ◽  
Bianca Zadrozny ◽  
Luiz H.C. Merschmann

In many important application domains, such as text categorization, biomolecular analysis, scene or video classification and medical diagnosis, instances are naturally associated with more than one class label, giving rise to multi-label classification problems. This has led, in recent years, to a substantial amount of research in multi-label classification. More specifically, feature selection methods have been developed to allow the identification of relevant and informative features for multi-label classification. This work presents a new feature selection method based on the lazy feature selection paradigm and specific for the multi-label context. Experimental results show that the proposed technique is competitive when compared to multi-label feature selection techniques currently used in the literature, and is clearly more scalable, in a scenario where there is an increasing amount of data.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Graziana Esposito ◽  
Bijorn Omar Balzamino ◽  
Egidio Stigliano ◽  
Filippo Biamonte ◽  
Andrea Urbani ◽  
...  

AbstractWe previously described the profibrogenic effect of NGF on conjunctival Fibroblasts (FBs) and its ability to trigger apoptosis in TGFβ1-induced myofibroblasts (myoFBs). Herein, cell apoptosis/signalling, cytokines’ signature in conditioned media and inflammatory as well as angiogenic pathway were investigated. Experimental myoFBs were exposed to NGF (0.1–100 ng/mL), at defined time-point for confocal and biomolecular analysis. Cells were analysed for apoptotic and cell signalling activation in cell extracts and for some inflammatory and proinflammatory/angiogenic factors’ activations. NGF triggered cJun overexpression and phospho-p65-NFkB nuclear translocation. A decreased Bcl2:Bax ratio and a significant expression of smad7 were confirmed in early AnnexinV-positive myoFBs. A specific protein signature characterised the conditioned media: a dose dependent decrease occurred for IL8, IL6 while a selective increase was observed for VEGF and cyr61 (protein/mRNA). TIMP1 levels were unaffected. Herein, NGF modulation of smad7, the specific IL8 and IL6 as well as VEGF and cyr61 modulation deserve more attention as opening to alternative approaches to counteract fibrosis.


2017 ◽  
Author(s):  
Karim Vindas ◽  
Elodie Engel ◽  
Patrick Garrigue ◽  
Thierry Livache ◽  
Stéphane Arbault ◽  
...  

2011 ◽  
Vol 25 ◽  
pp. 63-66 ◽  
Author(s):  
Adam L. Washburn ◽  
Matthew S. Luchansky ◽  
Melinda S. McClellan ◽  
Ryan C. Bailey

2000 ◽  
Vol 31 (7) ◽  
pp. 633-635 ◽  
Author(s):  
David L. Dickensheets ◽  
David D. Wynn-Williams ◽  
Howell G. M. Edwards ◽  
Christian Schoen ◽  
Chelle Crowder ◽  
...  

2014 ◽  
Vol 86 (18) ◽  
pp. 9020-9028 ◽  
Author(s):  
Konstantin O. Nagornov ◽  
Mikhail V. Gorshkov ◽  
Anton N. Kozhinov ◽  
Yury O. Tsybin

2005 ◽  
Author(s):  
Chia-Fu Chou ◽  
Jian Gu ◽  
Qihuo Wei ◽  
Yingjie Liu ◽  
Ravi Gupta ◽  
...  

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