AUTOMATED SCREENING OF DIABETIC RETINOPATHY WITH OPTIMIZED DEEP CONVOLUTIONAL NEURAL NETWORK: ENHANCED MOTH FLAME MODEL

2021 ◽  
Vol 21 (01) ◽  
pp. 2150005
Author(s):  
ARUN T NAIR ◽  
K. MUTHUVEL

Nowadays, analysis on retinal image exists as one of the challenging area for study. Numerous retinal diseases could be recognized by analyzing the variations taking place in retina. However, the main disadvantage among those studies is that, they do not have higher recognition accuracy. The proposed framework includes four phases namely, (i) Blood Vessel Segmentation (ii) Feature Extraction (iii) Optimal Feature Selection and (iv) Classification. Initially, the input fundus image is subjected to blood vessel segmentation from which two binary thresholded images (one from High Pass Filter (HPF) and other from top-hat reconstruction) are acquired. These two images are differentiated and the areas that are common to both are said to be the major vessels and the left over regions are fused to form vessel sub-image. These vessel sub-images are classified with Gaussian Mixture Model (GMM) classifier and the resultant is summed up with the major vessels to form the segmented blood vessels. The segmented images are subjected to feature extraction process, where the features like proposed Local Binary Pattern (LBP), Gray-Level Co-Occurrence Matrix (GLCM) and Gray Level Run Length Matrix (GLRM) are extracted. As the curse of dimensionality seems to be the greatest issue, it is important to select the appropriate features from the extracted one for classification. In this paper, a new improved optimization algorithm Moth Flame with New Distance Formulation (MF-NDF) is introduced for selecting the optimal features. Finally, the selected optimal features are subjected to Deep Convolutional Neural Network (DCNN) model for classification. Further, in order to make the precise diagnosis, the weights of DCNN are optimally tuned by the same optimization algorithm. The performance of the proposed algorithm will be compared against the conventional algorithms in terms of positive and negative measures.

2020 ◽  
Vol 13 (3) ◽  
pp. 283-310 ◽  
Author(s):  
Ambaji S. Jadhav ◽  
Pushpa B. Patil ◽  
Sunil Biradar

PurposeDiabetic retinopathy (DR) is a central root of blindness all over the world. Though DR is tough to diagnose in starting stages, and the detection procedure might be time-consuming even for qualified experts. Nowadays, intelligent disease detection techniques are extremely acceptable for progress analysis and recognition of various diseases. Therefore, a computer-aided diagnosis scheme based on intelligent learning approaches is intended to propose for diagnosing DR effectively using a benchmark dataset.Design/methodology/approachThe proposed DR diagnostic procedure involves four main steps: (1) image pre-processing, (2) blood vessel segmentation, (3) feature extraction, and (4) classification. Initially, the retinal fundus image is taken for pre-processing with the help of Contrast Limited Adaptive Histogram Equalization (CLAHE) and average filter. In the next step, the blood vessel segmentation is carried out using a segmentation process with optimized gray-level thresholding. Once the blood vessels are extracted, feature extraction is done, using Local Binary Pattern (LBP), Texture Energy Measurement (TEM based on Laws of Texture Energy), and two entropy computations – Shanon's entropy, and Kapur's entropy. These collected features are subjected to a classifier called Neural Network (NN) with an optimized training algorithm. Both the gray-level thresholding and NN is enhanced by the Modified Levy Updated-Dragonfly Algorithm (MLU-DA), which operates to maximize the segmentation accuracy and to reduce the error difference between the predicted and actual outcomes of the NN. Finally, this classification error can correctly prove the efficiency of the proposed DR detection model.FindingsThe overall accuracy of the proposed MLU-DA was 16.6% superior to conventional classifiers, and the precision of the developed MLU-DA was 22% better than LM-NN, 16.6% better than PSO-NN, GWO-NN, and DA-NN. Finally, it is concluded that the implemented MLU-DA outperformed state-of-the-art algorithms in detecting DR.Originality/valueThis paper adopts the latest optimization algorithm called MLU-DA-Neural Network with optimal gray-level thresholding for detecting diabetic retinopathy disease. This is the first work utilizes MLU-DA-based Neural Network for computer-aided Diabetic Retinopathy diagnosis.


Author(s):  
Mali Mohammedhasan ◽  
Harun Uğuz

This paper proposes an incoming Deep Convolutional Neural Network (CNN) architecture for segmenting retinal blood vessels automatically from fundus images. Automatic segmentation performs a substantial role in computer-aided diagnosis of retinal diseases; it is of considerable significance as eye diseases as well as some other systemic diseases give rise to perceivable pathologic changes. Retinal blood vessel segmentation is challenging because of the excessive changes in the morphology of the vessels on a noisy background. Previous deep learning-based supervised methods suffer from the insufficient use of low-level features which is advantageous in semantic segmentation tasks. The proposed architecture makes use of both high-level features and low-level features to segment retinal blood vessels. The major contribution of the proposed architecture concentrates on two important factors; the first in its supplying of extremely modularized network architecture of aggregated residual connections which enable us to copy the learned layers from the shallower model and developing additional layers to identity mapping. The second is to improve the utilization of computing resources within the network. This is achieved through a skillfully crafted design that allows for increased depth and width of the network while maintaining the stability of its computational budget. Experimental results show the effectiveness of using aggregated residual connections in segmenting retinal vessels more accurately and clearly. Compared to the best existing methods, the proposed method outperformed other existing methods in different measures, comprised less false positives at fine vessels, and caressed more clear lines with sufficient details like the human annotator.


2020 ◽  
Vol 8 (1) ◽  
pp. 21-25
Author(s):  
Afolabi O. Joshua ◽  
◽  
Fulufhelo V. Nelwamondo ◽  
Gugulethu Mabuza-Hocquet

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