scholarly journals Deep belief network-based drug identification using near infrared spectroscopy

2017 ◽  
Vol 10 (02) ◽  
pp. 1630011 ◽  
Author(s):  
Huihua Yang ◽  
Baichao Hu ◽  
Xipeng Pan ◽  
Shengke Yan ◽  
Yanchun Feng ◽  
...  

Near infrared spectroscopy (NIRS) analysis technology, combined with chemometrics, can be effectively used in quick and nondestructive analysis of quality and category. In this paper, an effective drug identification method by using deep belief network (DBN) with dropout mechanism (dropout-DBN) to model NIRS is introduced, in which dropout is employed to overcome the overfitting problem coming from the small sample. This paper tests proposed method under datasets of different sizes with the example of near infrared diffuse reflectance spectroscopy of erythromycin ethylsuccinate drugs and other drugs, aluminum and nonaluminum packaged. Meanwhile, it gives experiments to compare the proposed method’s performance with back propagation (BP) neural network, support vector machines (SVMs) and sparse denoising auto-encoder (SDAE). The results show that for both binary classification and multi-classification, dropout mechanism can improve the classification accuracy, and dropout-DBN can achieve best classification accuracy in almost all cases. SDAE is similar to dropout-DBN in the aspects of classification accuracy and algorithm stability, which are higher than that of BP neural network and SVM methods. In terms of training time, dropout-DBN model is superior to SDAE model, but inferior to BP neural network and SVM methods. Therefore, dropout-DBN can be used as a modeling tool with effective binary and multi-class classification performance on a spectrum sample set of small size.

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Yunfa Fu ◽  
Rui Chen ◽  
Anmin Gong ◽  
Qian Qian ◽  
Ning Ding ◽  
...  

Brain-computer interaction based on motor imagery (MI) is an important brain-computer interface (BCI). Most methods for MI classification are based on electroencephalogram (EEG), and few studies have investigated signal processing based on MI-Functional Near-Infrared Spectroscopy (fNIRS). In addition, there is a need to improve the classification accuracy for MI fNIRS methods. In this study, a deep belief network (DBN) based on a restricted Boltzmann machine (RBM) was used to classify fNIRS signals of flexion and extension imagery involving the left and right arms. fNIRS signals from 16 channels covering the motor cortex area were recorded for each of 10 subjects executing or imagining flexion and extension involving the left and right arms. Oxygenated hemoglobin (HbO) concentration was used as a feature to train two RBMs that were subsequently stacked with an additional softmax regression output layer to construct DBN. We also explored the DBN model classification accuracy for the test dataset from one subject using training dataset from other subjects. The average DBN classification accuracy for flexion and extension movement and imagery involving the left and right arms was 84.35 ± 3.86% and 78.19 ± 3.73%, respectively. For a given DBN model, better classification results are obtained for test datasets for a given subject when the model is trained using dataset from the same subject than when the model is trained using datasets from other subjects. The results show that the DBN algorithm can effectively identify flexion and extension imagery involving the right and left arms using fNIRS. This study is expected to serve as a reference for constructing online MI-BCI systems based on DBN and fNIRS.


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Xueying Li ◽  
Pingping Fan ◽  
Zongmin Li ◽  
Guangyuan Chen ◽  
Huimin Qiu ◽  
...  

Changes in land cover will cause the changes in the climate and environmental characteristics, which has an important influence on the social economy and ecosystem. The main form of land cover is different types of soil. Compared with traditional methods, visible and near-infrared spectroscopy technology can classify different types of soil rapidly, effectively, and nondestructively. Based on the visible near-infrared spectroscopy technology, this paper takes the soil of six different land cover types in Qingdao, China orchards, woodlands, tea plantations, farmlands, bare lands, and grasslands as examples and establishes a convolutional neural network classification model. The classification results of different number of training samples are analyzed and compared with the support vector machine algorithm. Under the condition that Kennard–Stone algorithm divides the calibration set, the classification results of six different soil types and single six soil types by convolutional neural network are better than those by the support vector machine. Under the condition of randomly dividing the calibration set according to the proportion of 1/3 and 1/4, the classification results by convolutional neural network are also better. The aim of this study is to analyze the feasibility of land cover classification with small samples by convolutional neural network and, according to the deep learning algorithm, to explore new methods for rapid, nondestructive, and accurate classification of the land cover.


2021 ◽  
Vol 14 ◽  
Author(s):  
Kunqiang Qing ◽  
Ruisen Huang ◽  
Keum-Shik Hong

This study decodes consumers' preference levels using a convolutional neural network (CNN) in neuromarketing. The classification accuracy in neuromarketing is a critical factor in evaluating the intentions of the consumers. Functional near-infrared spectroscopy (fNIRS) is utilized as a neuroimaging modality to measure the cerebral hemodynamic responses. In this study, a specific decoding structure, called CNN-based fNIRS-data analysis, was designed to achieve a high classification accuracy. Compared to other methods, the automated characteristics, constant training of the dataset, and learning efficiency of the proposed method are the main advantages. The experimental procedure required eight healthy participants (four female and four male) to view commercial advertisement videos of different durations (15, 30, and 60 s). The cerebral hemodynamic responses of the participants were measured. To compare the preference classification performances, CNN was utilized to extract the most common features, including the mean, peak, variance, kurtosis, and skewness. Considering three video durations, the average classification accuracies of 15, 30, and 60 s videos were 84.3, 87.9, and 86.4%, respectively. Among them, the classification accuracy of 87.9% for 30 s videos was the highest. The average classification accuracies of three preferences in females and males were 86.2 and 86.3%, respectively, showing no difference in each group. By comparing the classification performances in three different combinations (like vs. so-so, like vs. dislike, and so-so vs. dislike) between two groups, male participants were observed to have targeted preferences for commercial advertising, and the classification performance 88.4% between “like” vs. “dislike” out of three categories was the highest. Finally, pairwise classification performance are shown as follows: For female, 86.1% (like vs. so-so), 87.4% (like vs. dislike), 85.2% (so-so vs. dislike), and for male 85.7, 88.4, 85.1%, respectively.


2020 ◽  
pp. 096703352096669
Author(s):  
Miao-Na Zeng ◽  
Shao-Yan Zheng

Maca ( Lepidium meyenii Walp.) is a cruciferous edible and medicinal plant rich in nutrients. As maca demand in the international market is gradually increasing, dishonest people have been using low-priced alternatives to either adulterate or falsify maca and increase their profit. Existing methods to identify and quantify adulterated maca are laborious, expensive, destructive, time-consuming, and environmentally unfriendly. Thus, it is imperative to develop a method to overcome these problems to effectively authenticate maca products. We combine near infrared spectroscopy with chemometrics to classify and quantify maca powder adulteration by turnip and radish powder. Different maca samples were adulterated with turnip and radish powder individually at different percentages (5–95%). Specifically, discriminant analysis based on a support vector machine provides a classification accuracy of 100%, allowing near infrared spectroscopy to be used to distinguish maca powder adulteration. Furthermore, to calibrate a regression model, we evaluated the partial least squares (PLS), interval PLS, and synergy interval PLS (siPLS). The siPLS models were determined as the best models for the quantification of maca powder adulterated with turnip and radish powder, in which the correlation coefficients were both 0.97 with root-mean-square error of prediction values of 5.79% and 5.85% for the two models, respectively. The combination of near infrared spectroscopy and chemometrics can provide a fast, simple, and environment-friendly analytical method for identifying and quantifying the properties of maca.


2010 ◽  
Vol 129-131 ◽  
pp. 306-311 ◽  
Author(s):  
Pai Li ◽  
Hong Fu Zhang ◽  
Yao Xiang Li ◽  
Ya Zhao Zhang ◽  
Hui Juan Zhang

Application of BP neural network and NIRS for larch wood density prediction was investigated in this paper. The original spectra were collected and pretreated with the first derivative and 9 point smoothing. Eleven typical wave lengths were selected as BP network inputs to establish prediction model for wood density. Model was validated using cross-validation approach. The prediction correlation coefficient (R) is 0.916 while the root mean square error of prediction (RMSEP) is 0.0221. The results showed that using BP neural network in near-infrared spectroscopy calibration could significantly improve the model performance in order to rapidly and accurately predict wood density.


2021 ◽  
Vol 12 ◽  
Author(s):  
Po-Han Chou ◽  
Yun-Han Yao ◽  
Rui-Xuan Zheng ◽  
Yi-Long Liou ◽  
Tsung-Te Liu ◽  
...  

Backgrounds: Reduced brain cortical activity over the frontotemporal regions measured by near infrared spectroscopy (NIRS) has been reported in patients with first-episode schizophrenia (FES). This study aimed to differentiate between patients with FES and healthy controls (HCs) on basis of the frontotemporal activity measured by NIRS with a support vector machine (SVM) and deep neural network (DNN) classifier. In addition, we compared the accuracy of performance of SVM and DNN.Methods: In total, 33 FES patients and 34 HCs were recruited. Their brain cortical activities were measured using NIRS while performing letter and category versions of verbal fluency tests (VFTs). The integral and centroid values of brain cortical activity in the bilateral frontotemporal regions during the VFTs were selected as features in SVM and DNN classifier.Results: Compared to HCs, FES patients displayed reduced brain cortical activity over the bilateral frontotemporal regions during both types of VFTs. Regarding the classifier performance, SVM reached an accuracy of 68.6%, sensitivity of 70.1%, and specificity of 64.6%, while DNN reached an accuracy of 79.7%, sensitivity of 88.8%, and specificity of 74.9% in the classification of FES patients and HCs.Conclusions: Compared to findings of previous structural neuroimaging studies, we found that using DNN to measure the NIRS signals during the VFTs to differentiate between FES patients and HCs could achieve a higher accuracy, indicating that NIRS can be used as a potential marker to classify FES patients from HCs. Future additional independent datasets are needed to confirm the validity of our model.


Sign in / Sign up

Export Citation Format

Share Document