The Data Problem in Data Mining

2015 ◽  
Vol 16 (2) ◽  
pp. 38-45 ◽  
Author(s):  
Albrecht Zimmermann
Keyword(s):  
Data Mining ◽  
Data Problem

scholarly journals Virtual Screening of Drug Proteins Based on Imbalance Data Mining

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Peng Li ◽  
Lili Yin ◽  
Bo Zhao ◽  
Yuezhongyi Sun
Keyword(s):  
Data Mining ◽  
Molecular Docking ◽  
Virtual Screening ◽  
Test Data ◽  
Imbalanced Data ◽  
Screening Process ◽  
Active Compounds ◽  
Data Imbalance ◽  
Imbalance Problem ◽  
Data Problem

To address the imbalanced data problem in molecular docking-based virtual screening methods, this paper proposes a virtual screening method for drug proteins based on imbalanced data mining, which introduces machine learning technology into the virtual screening technology for drug proteins to deal with the imbalanced data problem in the virtual screening process and improve the accuracy of the virtual screening. First, to address the data imbalance problem caused by the large difference between the number of active compounds and the number of inactive compounds in the docking conformation generated by the actual virtual screening process, this paper proposes a way to improve the data imbalance problem using SMOTE combined with genetic algorithm to synthesize new active compounds artificially by upsampling active compounds. Then, in order to improve the accuracy in the virtual screening process of drug proteins, the idea of integrated learning is introduced, and the random forest (RF) extended from Bagging integrated learning technique is combined with the support vector machine (SVM) technique, and the virtual screening of molecular docking conformations using RF-SVM technique is proposed to improve the prediction accuracy of active compounds in docking conformations. To verify the effectiveness of the proposed technique, first, HIV-1 protease and SRC kinase were used as test data for the experiments, and then, CA II was used to validate the model of the test data. The virtual screening of drug proteins using the proposed method in this paper showed an improvement in both enrichment factor (EF) and AUC compared with the use of the traditional virtual screening, for the test dataset. Therefore, it can be shown that the proposed method can effectively improve the accuracy of drug virtual screening.

scholarly journals Data mining in education: Children living or working on the street with lost data problem

2021 ◽  
Vol 13 (2) ◽  
pp. 72-75
Author(s):  
Sekerci Reyhan ◽  
Karatas Süleyman ◽  
Güven Beyhan ◽  
Demir Levent ◽  
Güven Alper
Keyword(s):  
Data Mining ◽  
Data Problem

Data Mining and Machine Learning

2020 ◽  
Author(s):  
Mohammed J. Zaki ◽  
Wagner Meira, Jr
Keyword(s):  
Machine Learning ◽  
Data Mining

Heart Rate Variability, Emotions, and Music

2010 ◽  
Vol 24 (2) ◽  
pp. 112-119 ◽  
Author(s):  
F. Riganello ◽  
A. Candelieri ◽  
M. Quintieri ◽  
G. Dolce
Keyword(s):  
Data Mining ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Vegetative State ◽  
Low Frequency ◽  
Emotional Reactions ◽  
Heart Beat ◽  
Healthy Controls ◽  
Frequency Spectra ◽  
Emotional Value

The purpose of the study was to identify significant changes in heart rate variability (an emerging descriptor of emotional conditions; HRV) concomitant to complex auditory stimuli with emotional value (music). In healthy controls, traumatic brain injured (TBI) patients, and subjects in the vegetative state (VS) the heart beat was continuously recorded while the subjects were passively listening to each of four music samples of different authorship. The heart rate (parametric and nonparametric) frequency spectra were computed and the spectra descriptors were processed by data-mining procedures. Data-mining sorted the nu_lf (normalized parameter unit of the spectrum low frequency range) as the significant descriptor by which the healthy controls, TBI patients, and VS subjects’ HRV responses to music could be clustered in classes matching those defined by the controls and TBI patients’ subjective reports. These findings promote the potential for HRV to reflect complex emotional stimuli and suggest that residual emotional reactions continue to occur in VS. HRV descriptors and data-mining appear applicable in brain function research in the absence of consciousness.

Post, Mine, and Be Disturbed: Social Media Data Mining

PsycCRITIQUES ◽  
2016 ◽  
Vol 61 (51) ◽  
Author(s):  
Daniel Keyes
Keyword(s):  
Data Mining ◽  
Social Media ◽  
Social Media Data ◽  
Media Data
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