Mechanisms of Food Intake Repression in Indispensable Amino Acid Deficiency

2007 ◽  
Vol 27 (1) ◽  
pp. 63-78 ◽  
Author(s):  
Dorothy W. Gietzen ◽  
Shuzhen Hao ◽  
Tracy G. Anthony
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Amino Acid Deficiency ◽  
Indispensable Amino Acid ◽  
Acid Deficiency

scholarly journals Meal Patterns Reveal Differential Effects of Vagotomy and Tropisetron on Responses to Indispensable Amino Acid Deficiency in Rats

1996 ◽  
Vol 126 (6) ◽  
pp. 1722-1731 ◽  
Author(s):  
Lesa F. Erecius ◽  
Kimberly D. Dixon ◽  
Jennifer C. Jiang ◽  
Dorothy W. Gietzen
Keyword(s):  
Amino Acid ◽  
Amino Acid Deficiency ◽  
Meal Patterns ◽  
Differential Effects ◽  
Indispensable Amino Acid ◽  
Acid Deficiency

Role of MAP kinase in signaling indispensable amino acid deficiency in the brain

2002 ◽  
Vol 105 (1-2) ◽  
pp. 11-18 ◽  
Author(s):  
James W Sharp ◽  
Linda J Magrum ◽  
Dorothy W Gietzen
Keyword(s):  
Amino Acid ◽  
Map Kinase ◽  
Amino Acid Deficiency ◽  
Indispensable Amino Acid ◽  
Acid Deficiency ◽  
The Brain

Anorectic responses to dietary amino acid imbalance: effects of vagotomy and tropisetron

1994 ◽  
Vol 266 (6) ◽  
pp. R1922-R1927 ◽  
Author(s):  
B. S. Washburn ◽  
J. C. Jiang ◽  
S. L. Cummings ◽  
K. Dixon ◽  
D. W. Gietzen
Keyword(s):  
Amino Acid ◽  
Food Intake ◽  
Treated Group ◽  
Amino Acid Deficiency ◽  
Full Effect ◽  
Acid Deficiency ◽  
Dietary Amino Acid ◽  
Amino Acid Imbalance ◽  
Diet Intake ◽  
Vagal Function

We investigated the roles of the vagus nerve and the serotonin3 (5-HT3) receptor in mediating the food intake depression associated with amino acid deficiency. The food intake of sham-operated (sham) rats given an isoleucine-imbalanced (IMB) diet was reduced to < 40% of control basal (BAS) diet intake (P = 0.0009), and pretreatment with the 5-HT3 antagonist tropisetron (Trop) increased IMB intake by twofold over the vehicle (VEH)-treated group (P < or = 0.0001), as we have reported before. However, after subdiaphragmatic vagotomy (VAGX), IMB intake was increased to a level intermediate between the sham-VEH and sham-Trop groups, while administration of Trop did not increase IMB intake over VAGX alone. By the end of day 1, the VAGX-Trop group had eaten only 1 g more of IMB than the VAGX-VEH group (NS). We conclude that 1) the vagus is among the physiological systems involved in the anorectic responses to IMB and 2) intact vagal function is necessary for the full effect of 5-HT3 antagonists in alleviating the anorectic responses to IMB.

HOXB9 acts as a negative regulator of activated human T cells in response to amino acid deficiency

2016 ◽  
Vol 94 (6) ◽  
pp. 612-617 ◽  
Author(s):  
Keitaro Hayashi ◽  
Motoshi Ouchi ◽  
Hitoshi Endou ◽  
Naohiko Anzai
Keyword(s):  
T Cells ◽  
Amino Acid ◽  
Negative Regulator ◽  
Amino Acid Deficiency ◽  
Human T Cells ◽  
Acid Deficiency
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