Synthesis and Optoelectronic Properties of Free-Standing Polythiophene Cross-Linking Polycarbazole Films

Poly(N-isopropylacrylamide) (pNIPAM) based copolymer microgels were used to create free-standing, transferable, thermoresponsive membranes. The microgels were synthesized by copolymerization of NIPAM with N-benzylhydrylacrylamide (NBHAM). Monolayers of these colloidal gels were...

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On-Chip Fabrication and In-Flow 3D-Printing of Cell-Laden Microgel Constructs: From Chip to Scaffold Materials in One Integral Process

10.26434/chemrxiv.14564508 ◽

2021 ◽

Author(s):

Stephan Förster ◽

Jürgen Groll ◽

Benjamin Reineke ◽

Stephan Hauschild ◽

Ilona Paulus ◽

...

Keyword(s):

3D Printing ◽

Three Dimensional ◽

Cross Linking ◽

Cell Protection ◽

Free Standing ◽

Produce Cell ◽

Chip Fabrication ◽

Integral Process ◽

Scaffold Materials ◽

On Chip

Bioprinting has evolved into a thriving technology for the fabrication of cell-laden scaffolds. Bioinks are the most critical component for bioprinting. Recently, microgels have been introduced as a very promising bioink enabling cell protection and the control of the cellular microenvironment. However, their microfluidic fabrication inherently seemed to be a limitation. Here we introduce a direct coupling of microfluidics and 3D-printing for the microfluidic production of cell-laden microgels with direct in-flow bioprinting into stable scaffolds. The methodology enables the continuous on-chip encapsulation of cells into monodisperse microdroplets with subsequent in-flow cross-linking to produce cell-laden microgels, which after exiting a microtubing are automatically jammed into thin continuous microgel filaments. The integration into a 3D printhead allows direct in-flow printing of the filaments into free-standing three-dimensional scaffolds. The method is demonstrated for different cross-linking methods and cell lines. With this advancement, microfluidics is no longer a bottleneck for biofabrication. <br>

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On-Chip Fabrication and In-Flow 3D-Printing of Cell-Laden Microgel Constructs: From Chip to Scaffold Materials in One Integral Process

10.26434/chemrxiv.14564508.v1 ◽

2021 ◽

Author(s):

Stephan Förster ◽

Jürgen Groll ◽

Benjamin Reineke ◽

Stephan Hauschild ◽

Ilona Paulus ◽

...

Keyword(s):

3D Printing ◽

Three Dimensional ◽

Cross Linking ◽

Cell Protection ◽

Free Standing ◽

Produce Cell ◽

Chip Fabrication ◽

Integral Process ◽

Scaffold Materials ◽

On Chip

Bioprinting has evolved into a thriving technology for the fabrication of cell-laden scaffolds. Bioinks are the most critical component for bioprinting. Recently, microgels have been introduced as a very promising bioink enabling cell protection and the control of the cellular microenvironment. However, their microfluidic fabrication inherently seemed to be a limitation. Here we introduce a direct coupling of microfluidics and 3D-printing for the microfluidic production of cell-laden microgels with direct in-flow bioprinting into stable scaffolds. The methodology enables the continuous on-chip encapsulation of cells into monodisperse microdroplets with subsequent in-flow cross-linking to produce cell-laden microgels, which after exiting a microtubing are automatically jammed into thin continuous microgel filaments. The integration into a 3D printhead allows direct in-flow printing of the filaments into free-standing three-dimensional scaffolds. The method is demonstrated for different cross-linking methods and cell lines. With this advancement, microfluidics is no longer a bottleneck for biofabrication. <br>

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Composite free-standing films of polydopamine/polyethyleneimine grown at the air/water interface

RSC Advances ◽

10.1039/c4ra04549a ◽

2014 ◽

Vol 4 (85) ◽

pp. 45415-45418 ◽

Cited By ~ 52

Author(s):

Hao-Cheng Yang ◽

Wei Xu ◽

Yong Du ◽

Jian Wu ◽

Zhi-Kang Xu

Keyword(s):

Cross Linking ◽

Water Interface ◽

Free Standing ◽

Solution Interface ◽

Air Water Interface

A polydopamie/polyethyleneimine composite free-standing film is obtained via a facile oxidation and cross-linking process at the air/solution interface.

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Carbon Nanomembranes

Physical Sciences Reviews ◽

10.1515/psr-2016-0105 ◽

2017 ◽

Vol 2 (3) ◽

Author(s):

Polina Angelova ◽

Armin Gölzhäuser

Keyword(s):

Young’S Modulus ◽

Young's Modulus ◽

Molecular Size ◽

Bulge Test ◽

Cross Linking ◽

Level Control ◽

Mechanical Stiffness ◽

Free Standing ◽

Bulge Testing ◽

Structural And Functional Properties

Abstract This chapter describes the formation and properties of one nanometer thick carbon nanomembranes (CNMs), made by electron induced cross-linking of aromatic self-assembled monolayers (SAMs). The cross-linked SAMs are robust enough to be released from the surface and placed on solid support or over holes as free-standing membranes. Annealing at ~1000K transforms CNMs into graphene accompanied by a change of mechanical stiffness and electrical resistance. The developed fabrication approach is scalable and provides molecular level control over thickness and homogeneity of the produced CNMs. The mechanisms of electron-induced cross-linking process are discussed in details. A variety of polyaromatic thiols: oligophenyls as well as small and extended condensed polycyclic hydrocarbons have been successfully employed, demonstrating that the structural and functional properties of the resulting nanomembranes are strongly determined by the structure of molecular monolayers. The mechanical properties of CNMs (Young’s modulus, tensile strength and prestress) are characterized by bulge testing. The interpretation of the bulge test data relates the Young’s modulus to the properties of single molecules and to the structure of the pristine SAMs. The gas transport through the CNM is measured onto polydimethylsiloxane (PDMS) - thin film composite membrane. The established relationship of permeance and molecular size determines the molecular sieving mechanism of permeation through this ultrathin sheet.

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Electrospun cross-linked carbon nanofiber films as free-standing and binder-free anodes with superior rate performance and long-term cycling stability for sodium ion storage

Journal of Materials Chemistry A ◽

10.1039/c7ta05621d ◽

2017 ◽

Vol 5 (40) ◽

pp. 21343-21352 ◽

Cited By ~ 31

Author(s):

Xu Guo ◽

Xiaoting Zhang ◽

Huaihe Song ◽

Jisheng Zhou

Keyword(s):

Carbon Nanofiber ◽

Cycling Stability ◽

Sodium Ion ◽

Cross Linking ◽

Rate Performance ◽

Free Standing ◽

Ion Storage ◽

Binder Free ◽

Sodium Ion Storage

A novel cross-linking strategy is proposed to design electrospun carbon nanofiber films towards free-standing and binder-free electrodes for sodium-ion storage.

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