Method for prolonged ambulatory monitoring of high-amplitude propagated contractions from colon

1991 ◽  
Vol 261 (2) ◽  
pp. G263-G268 ◽  
Author(s):  
M. D. Crowell ◽  
G. Bassotti ◽  
L. J. Cheskin ◽  
M. M. Schuster ◽  
W. E. Whitehead
Keyword(s):  
Bowel Movement ◽  
Anal Verge ◽  
Ambulatory Monitoring ◽  
High Amplitude ◽  
X Ray ◽  
Pressure Transducers ◽  
Peristaltic Activity ◽  
Bowel Prep ◽  
Asymptomatic Individuals ◽  
State Pressure

This study monitored high-amplitude propagated contractions (HAPCs) in ambulating subjects over a 24-h period using a new ambulatory recording system. Twelve healthy volunteers aged 34 +/- 5.96 yr participated. Approximately 12 h after a Colyte bowel prep, a small catheter (OD less than 3 mm), containing three solid-state pressure transducers spaced 5 cm apart, was positioned by flexible sigmoidoscope at 40-50 cm from the anal verge. A battery-operated data recorder sampled the pressure at each port at 1 Hz and stored the values on all ports if any port exceeded 75 mmHg. At the conclusion of the 24-h period, an X-ray was taken to confirm the location of the catheter. Fifty-four percent of all HAPCs preceded a bowel movement by less than or equal to 1 h. Forty-nine percent of all HAPCs occurred within 1 h after a high-fat meal, and 33% occurred within 1 h of morning awakening. Reverse propagated waves, not previously described in the colon, were observed in three individuals. Spontaneous high-amplitude caudally propagated contractions occur 6.9 +/- 1.5 times/24 h in the sigmoid colon in ambulating asymptomatic individuals and are temporally related to defecation and meals. Peristaltic activity is decreased during sleep. This recording technique was reliable and well tolerated in all participants.

scholarly journals Discovery of high-amplitude X-ray variability in the Seyfert-LINER transition galaxy NGC 7589

2004 ◽  
Vol 353 (3) ◽  
pp. L29-L33 ◽  
Author(s):  
W. Yuan ◽  
St. Komossa ◽  
D. Xu ◽  
J. P. Osborne ◽  
M. G. Watson ◽  
...  
Keyword(s):  
High Amplitude ◽  
X Ray

Simultaneous Videoradiography and Computerized Pharyngeal Manometry — Videomanometry

1994 ◽  
Vol 35 (1) ◽  
pp. 30-34
Author(s):  
R. Olsson ◽  
H. Nilsson ◽  
O. Ekberg
Keyword(s):  
Solid State ◽  
Muscle Function ◽  
Barium Swallow ◽  
Pharyngeal Wall ◽  
Pressure Transducers ◽  
Pharyngoesophageal Segment ◽  
Fluoroscopic Control ◽  
Pharyngeal Manometry ◽  
State Pressure

To obtain more information about muscle function in patients with dysphagia, simultaneous barium swallow and computerized pharyngeal manometry with solid-state pressure transducers was employed for the evaluation of the pharynx and the pharyngoesophageal segment (PES) in 30 consecutive patients. The manometry catheter was positioned under fluoroscopic control, providing localized measurements of the intraluminal pressures in the pharynx. Sixteen patients had a normal barium swallow. In 5 (31%) of these the manometry disclosed PES dysfunction, i.e. increased resting pressures between swallows in 3 patients (mean 120 ± 13 mm Hg), and increased contraction pressures during peristalsis in 2 (mean 297 ± 21 mm Hg). Barium swallow and manometry are complementary: the former reflecting transport through the pharynx and penetration to the airways, the latter the intraluminal pressures created by the pharyngeal wall. The combination of barium swallow and manometry gives information about pressure in relation to bolus transport, which may elucidate pharyngeal dysfunction.

Staging Rectal Cancer: The Utility of Chest Radiograph and Chest Computed Tomography

2016 ◽  
Vol 82 (10) ◽  
pp. 1005-1008
Author(s):  
Michael P. O'Leary ◽  
Aaron B. Parrish ◽  
Cynthia M. Tom ◽  
Brian W. Maclaughlin ◽  
Beverley A. Petrie
Keyword(s):  
Rectal Cancer ◽  
Metastatic Cancer ◽  
Anal Verge ◽  
Cancer Staging ◽  
Chest Ct ◽  
X Ray ◽  
Primary Rectal Cancer ◽  
Abnormal Chest ◽  
Normal Chest ◽  
Chest X Ray

The National Comprehensive Cancer Network recommends that patients who are newly diagnosed with rectal cancer undergo staging CT scan of the chest. It is unclear whether posteroanterior and lateral chest radiography (X-ray) alone would provide adequate staging for most of these patients. A retrospective review was performed on all patients who had a two-view chest X-ray along with a chest CT for rectal cancer staging from 2007 to 2015. A total of 74 patients had both modalities. Sixty-three (85%) had a normal chest X-ray and 11 (15%) had an abnormal chest X-ray. Of the 63 patients with a normal chest X-ray, 40 (63%) had a corresponding normal chest CT and 23 (37%) had a lesion only noted on chest CT. Four patients (17%) in the latter group had metastatic cancer to the lung at the time of workup and four out of five of the tumors found to metastasize were within 5 cm from the anal verge. Our data suggest that a staging chest X-ray is unlikely to diagnose metastatic lungs lesions from a primary rectal cancer. Conversely, staging chest CT will accurately stage metastatic disease but will also reveal benign lung lesions in this patient population.

scholarly journals High-amplitude, long-term X-ray variability in the solar-type star HD 81809: The beginning of an X-ray activity cycle?

2004 ◽  
Vol 418 (1) ◽  
pp. L13-L16 ◽  
Author(s):  
F. Favata ◽  
G. Micela ◽  
S. L. Baliunas ◽  
J. H. M. M. Schmitt ◽  
M. Güdel ◽  
...  
Keyword(s):  
Activity Cycle ◽  
High Amplitude ◽  
Type Star ◽  
X Ray ◽  
Solar Type ◽  
Solar Type Star

scholarly journals X-ray quasi-periodic eruptions from two previously quiescent galaxies

Nature ◽  
2021 ◽  
Vol 592 (7856) ◽  
pp. 704-707
Author(s):  
R. Arcodia ◽  
A. Merloni ◽  
K. Nandra ◽  
J. Buchner ◽  
M. Salvato ◽  
...  
Keyword(s):  
Black Hole ◽  
Galactic Nuclei ◽  
Compact Object ◽  
High Amplitude ◽  
Optical Spectra ◽  
Orbital Evolution ◽  
Main Body ◽  
X Ray ◽  
Accretion Flows ◽  
Very High

AbstractQuasi-periodic eruptions (QPEs) are very-high-amplitude bursts of X-ray radiation recurring every few hours and originating near the central supermassive black holes of galactic nuclei1,2. It is currently unknown what triggers these events, how long they last and how they are connected to the physical properties of the inner accretion flows. Previously, only two such sources were known, found either serendipitously or in archival data1,2, with emission lines in their optical spectra classifying their nuclei as hosting an actively accreting supermassive black hole3,4. Here we report observations of QPEs in two further galaxies, obtained with a blind and systematic search of half of the X-ray sky. The optical spectra of these galaxies show no signature of black hole activity, indicating that a pre-existing accretion flow that is typical of active galactic nuclei is not required to trigger these events. Indeed, the periods, amplitudes and profiles of the QPEs reported here are inconsistent with current models that invoke radiation-pressure-driven instabilities in the accretion disk5–9. Instead, QPEs might be driven by an orbiting compact object. Furthermore, their observed properties require the mass of the secondary object to be much smaller than that of the main body10, and future X-ray observations may constrain possible changes in their period owing to orbital evolution. This model could make QPEs a viable candidate for the electromagnetic counterparts of so-called extreme-mass-ratio inspirals11–13, with considerable implications for multi-messenger astrophysics and cosmology14,15.

Diagnostic principles of immature epileptic (proepileptic) EEG activity in rats with genetic predisposition to absence epilepsy

2019 ◽  
pp. 89-97
Author(s):  
E. Yu. Sitnikova ◽  
K. S. Smirnov ◽  
V. V. Grubov ◽  
A. E. Hramov
Keyword(s):  
Genetic Predisposition ◽  
High Amplitude ◽  
Absence Epilepsy ◽  
Eeg Activity ◽  
Time Frequency ◽  
Age Related ◽  
Reliable Model ◽  
Spike Wave Discharges ◽  
Asymptomatic Individuals ◽  
Spike Wave

Introduction:Absence epilepsy is a specific neurological disorder characterized by brief episodes of loss of consciousness (absence) accompanied by high-amplitude “spike-wave” discharges in the electroencephalogram (EEG). WAG/Rij rats with a genetic predisposition to absence epilepsy are used as a reliable model of this disease. This model is beneficial for investigating basic mechanisms of absence epilepsy, including the development of spike-wave seizures.Purpose:Establishing diagnostic principles for immature forms of spikewave activity in EEG (so-called proepileptic activity) of WAG/Rij rats.Results:Diagnostic criteria are proposed for proepileptic EEG activity in rats, based on time-frequency analysis with the continuous wavelet transform and skeletons of wavelet surfaces. The algorithm was tested in “epileptic” and “asymptomatic” individuals. Rats with the “epileptic” phenotype demonstrated a decrease in number of proepileptic patterns between 5 and 7 months of age in parallel to an increase in the number of epileptic discharges that might relate to the transformation of proepileptic activity to epileptic. In rats with the “asymptomatic” phenotype, the age-related decline in the number of proepileptic patterns was not accompanied by the occurrence of spike-wave discharges. A decrease in the instantaneous frequency was found in a larger number of proepileptic patterns in “epileptic” WAG/Rij rats as compared to “asymptomatic” individuals.Practical relevance:A similar approach can be used for early diagnosis of absence epilepsy at the preclinical stage in patients with genetic predisposition.

537 Oversensing due to micro-air bubbles leading to inappropriate shocks in patient with subcutaneous implantable cardioverter defibrillator

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Francesca Seganfreddo ◽  
Michele Golino ◽  
Francesca Ceriani ◽  
Federica Matteo ◽  
Matteo Morello ◽  
...  
Keyword(s):  
Implantable Cardioverter Defibrillator ◽  
Early Period ◽  
Standard Technique ◽  
High Amplitude ◽  
Air Bubbles ◽  
Icd Implantation ◽  
X Ray ◽  
Cardioverter Defibrillator ◽  
Inappropriate Shocks ◽  
Chest X Ray

Abstract Aims Subcutaneous air has been reported as uncommon cause of early device malfunction after implantation of subcutaneous implantable cardioverter defibrillator (S-ICD). Methods and results A 43-year-old man was admitted to our hospital due to syncopal episodes. During a brain computed tomography (CT), he was resuscitated from cardiac arrest due to ventricular fibrillation. Further investigations excluded ischaemic heart disease and cardiac magnetic resonance showed signs of prior myocarditis. After successful screening, an S-ICD was inserted for secondary prevention using the standard technique. The chest X-ray excluded acute post-procedural complications. Three days after implantation, he experienced two inappropriate shocks while conscious. Device interrogation revealed frequent high-amplitude signals followed by two shocks (Figure 1A and B) that could be interpreted as oversensing. During provocative maneuvers on the generator case, minimal and intermittent noise only on the secondary sensing vector was observed. Lateral and antero-posterior chest X-ray excluded subcutaneous air. However, the general agreement based on previous reports was that oversensing as observed in Figures 1A and B was typical for noise due to micro-air bubbles in the connection between the lead and the generator case. As a consequence, the sensing vector was successfully changed and no other inappropriate shocks were observed during follow-up. Conclusions Entrapped micro-air bubbles in the connection between the leads and the generator case can cause inappropriate shocks in the early period after S-ICD implantation. Timely recognition of this complication is important to prevent inappropriate shocks. It can occur shortly after the procedure even if the intra-procedural parameters were normal and chest X-ray excluded acute complications. As demonstrated in our case, the device can be reprogrammed using another sensing vector to solve these oversensing problems.

scholarly journals A rare case of idiopathic ileocolic intussusception in an adult

2021 ◽  
Author(s):  
Muniba Mehmood ◽  
Uzair Yaqoob ◽  
Khaled Abdullah Rage ◽  
Hina Khan ◽  
Mujeeb Rehman Abbasi ◽  
...  
Keyword(s):  
Preoperative Diagnosis ◽  
Rare Case ◽  
Histopathological Examination ◽  
Anal Verge ◽  
Exploratory Laparotomy ◽  
Computed Tomography Scan ◽  
Ileocolic Intussusception ◽  
X Ray ◽  
Bleeding Per Rectum ◽  
Tomography Scan

Intussusception is an invagination of one segment of the bowel into its adjoining segment. In children, the cause is usually benign, while in adults it is secondary to a mass lesion. Here we present a case in which the preoperative diagnosis of intussusception secondary to colonic mass was made, but no definitive cause was identified by histopathology. A 30-year-old male presented with abdominal pain, altered bowel habits, weight loss, loose motions, bleeding per rectum, and vomiting. The abdomen was distended, firm, mildly tender, and guarded. A vague mass of 15 x 10 cm was palpated on the left upper quadrant. X-ray and ultrasound showed dilated small bowel. A computed tomography scan suggested ileoileal intussusception. Colonoscopy showed a growth at 15 cm of the anal verge. Exploratory laparotomy was performed, showing the presence of ileocolic intussusception with two large perforations. Subtotal colectomy with ileostomy was done. The histopathological examination showed signs of perforation.

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