Effects of Thermal Injury and of Skin Removal on Thyroid Function in the Rat

1958 ◽  
Vol 195 (3) ◽  
pp. 659-662 ◽  
Author(s):  
Seymour Reichlin ◽  
Zelig H. Lieberman

Thyroid I131 release rates have been measured in 6 rats before and after a 10–20% full thickness burn of the skin, and in 11 rats before and after resection of 10–20% of the dorsal skin surface. Thyroid function was inhibited for a variable period up to 30 hours after the burn in five of six animals. In contrast, flaying was followed in each of the 11 rats by increased thyroid function.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Barbara Helena Barcaro Machado ◽  
Ivy Dantas De Melo E. Silva ◽  
Walter Marou Pautrat ◽  
James Frame ◽  
Mohammad Najlah

AbstractMeasuring outcomes from treatments to the skin is either reliant upon patient’s subjective feedback or scale-based peer assessments. Three-Dimensional stereophotogrammetry intend to accurately quantify skin microtopography before and after treatments. The objective of this study is comparing the accuracy of stereophotogrammetry with a scale-based peer evaluation in assessing topographical changes to skin surface following laser treatment. A 3D stereophotogrammetry system photographed skin surface of 48 patients with facial wrinkles or scars before and three months after laser resurfacing, followed immediately by topical application of vitamin C. The software measured changes in skin roughness, wrinkle depth and scar volume. Images were presented to three observers, each independently scoring cutaneous improvement according to Investigator Global Aesthetic Improvement Scale (IGAIS). As for the results, a trend reflecting skin/scar improvement was reported by 3D SPM measurements and raters. The percentage of topographical change given by the raters matched 3D SPM findings. Agreement was highest when observers analysed 3D images. However, observers overestimated skin improvement in a nontreatment control whilst 3D SPM was precise in detecting absence of intervention. This study confirmed a direct correlation between the IGAIS clinical scale and 3D SPM and confirmed the efficacy and accuracy of the latter when assessing cutaneous microtopography alterations as a response to laser treatment.


1993 ◽  
Vol 18 (5-6) ◽  
pp. 437-443 ◽  
Author(s):  
Mark S. Bauer ◽  
James Kurtz ◽  
Andrew Winokur ◽  
Jennifer Phillips ◽  
Lisa B. Rubin ◽  
...  

1972 ◽  
Vol 70 (2) ◽  
pp. 266-272 ◽  
Author(s):  
J. H. Lazarus ◽  
E. H. Bennie

ABSTRACT Thyroid function was assessed in a prospective survey of 13 manicdepressive patients before and after 3 months on lithium carbonate and in a further 12 patients who had received lithium for 20 months. There was a significant increase in thyroid size as measured by quantitative scintiscanning in 8 patients in the first group. One male in the second group had a goitre. There was a rise in plasma TSH in the first group and a significant fall in saliva to plasma iodide. It is suggested that pathogenesis of lithium induced goitre is related to a disturbance in the iodide concentrating mechanism. Thyroid status should be evaluated in patients who are suitable for lithium therapy.


2009 ◽  
Vol 76 (6) ◽  
Author(s):  
Hu Yi-Feng ◽  
Chen Yi-Heng

In this paper we extend the M-integral concept (Eshelby, J. D., 1956, The Continuum Theory of Lattice Defects, Solid State Physics, F. Seitz and D. Turnbull, eds., Academic, New York, pp. 79–141; Eshelby, J. D., 1970, The Energy Momentum Tensor in Continuum Mechanics, Inelastic Behavior of Solids, M. F. Kanninen, ed., McGraw-Hill, New York, pp. 77–115; Eshelby, J. D., 1975, “The Elastic Energy-Momentum Tensor,” J. Elast., 5, pp. 321–335; Knowles, J. K., and Sternberg, E., 1972, “On a Class of Conservation Laws in Linearized and Finite Elastostatics,” Arch. Ration. Mech. Anal., 44, pp. 187–211; Budiansky, B., and Rice, J. R., 1973, “Conservation Laws and Energy Release Rates,” ASME J. Appl. Mech., 40, pp. 201–203; Freund, L. B., 1978, “Stress Intensity Factor Calculations Based on a Conservation Integral,” Int. J. Solids Struct., 14, pp. 241–250; Herrmann, G. A., and Herrmann, G., 1981, “On Energy Release Rates for a Plane Cracks,” ASME J. Appl. Mech., 48, pp. 525–530; King, R. B., and Herrmann, G., 1981, “Nondestructive Evaluation of the J- and M-Integrals,” ASME J. Appl. Mech., 48, pp. 83–87) to study the degradation of a brittle plan strip caused by irreversible evolution: the cracks coalescence under monotonically increasing loading. Attention is focused on the change of the M-integral before and after coalescence of two neighborly located cracks inclined each other. The influences of different orientations of the two cracks and different coalescence paths connecting the two cracks on the M-integral are studied in detail. Finite element analyses reveal that different orientations of the two cracks lead to different critical values of the M-integral at which the coalescence occurs. It is concluded that the M-integral does play an important role in the description of the damage extent and damage evolution. However, it only provides some outside variable features. This means that the complete failure mechanism due to damage evolution cannot be governed by a single parameter MC as proposed by Chang and Peng, 2004, “Use of M integral for Rubbery Material Problems Containing Multiple Defects,” J. Eng. Mech., 130(5), pp. 589–598. It is found that there is an inherent relation between the M-integral and the reduction of the effective elastic moduli as the orientation of one crack varies, i.e., the larger the M-integral is, the larger the reduction is. Of great significance is that the M-integral is inherently related to the change of the total potential energy for a damaged brittle material regardless of the detailed damage features or damage evolution. Therefore, this provides a useful and convenient experimental technique to measure the values of M-integral for a damaged brittle material from initial damage to final failure without use of many stain gages (King, R. B., and Herrmann, G., 1981, “Nondestructive Evaluation of the J- and M-Integrals,” ASME J. Appl. Mech., 48, pp. 83–87).


Pain Medicine ◽  
2016 ◽  
pp. pnw260 ◽  
Author(s):  
Margaux M. Salas ◽  
John L. Clifford ◽  
Jessica R. Hayden ◽  
Michael J. Iadarola ◽  
Dayna L. Averitt

2015 ◽  
Vol 4 (2) ◽  
pp. 83-91 ◽  
Author(s):  
Jesse C. Wu ◽  
Lloyd F. Rose ◽  
Robert J. Christy ◽  
Kai P. Leung ◽  
Rodney K. Chan

2010 ◽  
Vol 41 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Charles C. Wykoff ◽  
Audina M. Berrocal ◽  
Amy C. Schefler ◽  
Stephen R. Uhlhorn ◽  
Marco Ruggeri ◽  
...  

2020 ◽  
Vol 16 (2) ◽  
pp. 261-269
Author(s):  
Paula Carolina Dambros Granzotto ◽  
Cleo Otaviano Mesa Junior ◽  
Rodrigo Strobel ◽  
Rosana Radominski ◽  
Hans Graf ◽  
...  

Burns ◽  
2015 ◽  
Vol 41 (8) ◽  
pp. 1796-1804 ◽  
Author(s):  
Jennifer E. Nyland ◽  
Samuel A. McLean ◽  
Dayna L. Averitt

2015 ◽  
Vol 16 (4) ◽  
pp. S45
Author(s):  
J. Clifford ◽  
M. Salas ◽  
M. McIntyre ◽  
D. Wong

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