Elastic characteristics of isolated segments of human aortas under dynamic conditions

1959 ◽  
Vol 14 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Freeman W. Cope
Keyword(s):  
Hysteresis Loop ◽  
Thoracic Aorta ◽  
Measuring Equipment ◽  
Time Lag ◽  
Measuring System ◽  
Time Lags ◽  
Descending Thoracic Aorta ◽  
System A ◽  
Sufficient Magnitude ◽  
Elastic Characteristics

When isolated segments of human descending thoracic aorta were caused to change their volume rapidly and continuously in sinusoidal fashion with pulse pressures and pulse rates maintained in the physiological range, the resulting pressure-volume curves showed slight but consistent increases in stiffness, compared to pressure-volume curves obtained on the same specimens when inflated stepwise. There was introduced into the pressure measuring system a time lag of sufficient magnitude to eliminate the hysteresis loop. The extent of hysteresis in the aorta was not determined because time lags in the aorta could not be distinguished from time lags in the measuring equipment. Submitted on September 10, 1958

Management of thoracic aortic lesions - the future is endovascular

VASA ◽  
2012 ◽  
Vol 41 (3) ◽  
pp. 163-176 ◽  
Author(s):  
Weidenhagen ◽  
Bombien ◽  
Meimarakis ◽  
Geisler ◽  
A. Koeppel
Keyword(s):  
Thoracic Aorta ◽  
Clinical Decision Making ◽  
Treatment Options ◽  
Clinical Decision ◽  
Clinical Results ◽  
Treatment Modalities ◽  
Traumatic Rupture ◽  
Descending Thoracic Aorta ◽  
New Treatment ◽  
Aneurysm Dissection

Open surgical repair of lesions of the descending thoracic aorta, such as aneurysm, dissection and traumatic rupture, has been the “state-of-the-art” treatment for many decades. However, in specialized cardiovascular centers, thoracic endovascular aortic repair and hybrid aortic procedures have been implemented as novel treatment options. The current clinical results show that these procedures can be performed with low morbidity and mortality rates. However, due to a lack of randomized trials, the level of reliability of these new treatment modalities remains a matter of discussion. Clinical decision-making is generally based on the experience of the vascular center as well as on individual factors, such as life expectancy, comorbidity, aneurysm aetiology, aortic diameter and morphology. This article will review and discuss recent publications of open surgical, hybrid thoracic aortic (in case of aortic arch involvement) and endovascular repair in complex pathologies of the descending thoracic aorta.

Penetrating atherosclerotic ulcer aneurysm of the innominate artery

VASA ◽  
2009 ◽  
Vol 38 (3) ◽  
pp. 263-266 ◽  
Author(s):  
Yuan ◽  
Tager
Keyword(s):  
Conservative Treatment ◽  
Thoracic Aorta ◽  
Open Surgery ◽  
Innominate Artery ◽  
Ruptured Aneurysm ◽  
Descending Thoracic Aorta ◽  
Penetrating Atherosclerotic Ulcer ◽  
Descending Aorta

Penetrating atherosclerotic ulcer of the aorta is uncommon, and usually develops in the descending thoracic aorta. Rarely this condition involves the branch vessels of the aorta. We report a case of ruptured aneurysm of the innominate artery resulting from penetrating atherosclerotic ulcer. Open surgery was the treatment of choice for the ruptured aneurysm, while conservative treatment was recommended for the associated penetrating atherosclerotic ulcers of the descending aorta.

scholarly journals In Vitro Model of Mycobacterial Growth Arrest Using Nitric Oxide with Limited Air

2008 ◽  
Vol 53 (1) ◽  
pp. 157-161 ◽  
Author(s):  
Syed Hussain ◽  
Muhammad Malik ◽  
Lanbo Shi ◽  
Maria Laura Gennaro ◽  
Karl Drlica
Keyword(s):  
Nitric Oxide ◽  
In Vitro Model ◽  
Transition Period ◽  
Time Lag ◽  
Growth Arrest ◽  
Ring Structure ◽  
Time Lags ◽  
Vitro Model ◽  
Mycobacterial Growth

ABSTRACT An in vitro model of mycobacterial growth arrest was developed using Mycobacterium bovis BCG. When an exponentially growing culture was transferred to an evacuated tube, growth continued; treatment with a source of nitric oxide (diethylenetriamine-nitric oxide adduct [DETA-NO] at 50 μM) halted growth immediately, and aeration restored growth. When the period of growth arrest exceeded 4 h, a time lag occurred before aeration could restore growth. The lag time was maximal (24 h) after 16 h of growth arrest. These time lags indicated that one transition period was required for cells to achieve full arrest of growth and another for them to recover fully from growth arrest. DETA-NO-induced growth arrest failed to protect from the lethal effects of anaerobic shock, which caused rapid lysis of both growing and growth-arrested cells. While growth arrest had little effect on the lethal action of rifampin, it eliminated isoniazid lethality. Growth arrest reduced but did not eliminate fluoroquinolone lethality. Two fluoroquinolones, moxifloxacin and gatifloxacin, were equally lethal to exponentially growing cells, but moxifloxacin was more active during growth arrest. This difference is attributed to the fluoroquinolone C-7 ring structure, the only difference between the compounds. Collectively these data characterize a new system for halting mycobacterial growth that may be useful for evaluating new antituberculosis agents.

IRREVERSIBLE INVESTMENT, OPERATING FLEXIBILITY, AND TIME LAGS

2010 ◽  
Vol 27 (02) ◽  
pp. 271-286 ◽  
Author(s):  
RYUTA TAKASHIMA ◽  
MAKOTO GOTO ◽  
MOTOH TSUJIMURA
Keyword(s):  
Time Lag ◽  
Peak Load ◽  
Price Volatility ◽  
Optimal Investment ◽  
Capacity Expansion ◽  
Fixed Cost ◽  
Time Lags ◽  
Investment Timing ◽  
Power Company ◽  
Optimal Investment Problem

We consider an optimal investment problem when a firm such as an electric power company has the operational flexibility to expand and contract capacity with fixed cost. This problem is formulated as an impulse control problem combined with optimal stopping. Consequently, we obtain optimal investment timing, optimal capacity expansion and contraction timing, and the investment value. We also show investment, capacity expansion and contraction rule are influenced by the price volatility and the initial capacity is also influenced by the ratio between base-load plant and peak-load plant. In addition, we investigate how time lag between investment and operation influences the investment rule.

scholarly journals Aneurysms of the descending thoracic aorta: Three hundred sixty-six consecutive cases resected without paraplegia

1995 ◽  
Vol 21 (3) ◽  
pp. 385-391 ◽  
Author(s):  
Alain Verdant ◽  
Robert Cossette ◽  
Arthur Pagè ◽  
Richard Baillot ◽  
Leon Dontigny ◽  
...  
Keyword(s):  
Thoracic Aorta ◽  
Descending Thoracic Aorta
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