Energy metabolism of the albino rat at minimal levels of spontaneous muscular activity.

1968 ◽  
Vol 24 (1) ◽  
pp. 11-16 ◽  
Author(s):  
P O Bramante
1934 ◽  
Vol 8 (5) ◽  
pp. 535-552 ◽  
Author(s):  
E. B. Forbes ◽  
Max Kriss ◽  
R. C. Miller
Keyword(s):  

CRANIO® ◽  
2001 ◽  
Vol 19 (4) ◽  
pp. 294-301 ◽  
Author(s):  
Kaoru Satoh ◽  
Taihiko Yamaguchi ◽  
Kosetsu Komatsu ◽  
Nobuo Inoue ◽  
Kazuyuki Minowa ◽  
...  

1961 ◽  
Vol 16 (6) ◽  
pp. 982-990 ◽  
Author(s):  
Pietro O. Bramante

Oxygen consumption (Vo2) and spontaneous muscular activity of albino rats, recorded with apparatus previously described and quantitated with a new technique, exhibited highly significant correlations when paired in successive 10-min periods with a 5-min lag of Vo2 ( y) in respect to spontaneous muscular activity ( x). Since fasting and nonfasting male rats of different weights (range: 156—462 g) showed at perfect rest a quite narrow scatter of metabolic rates ( y = yaKgb ± 6% se) and since y was linearly correlated with x (se = 7.1% fasting; 5.5% nonfasting), theoretical Vo2 values could be predicted from y = Kgyb( m + nx) when the appropriate value of b, experimentally found (in this case 0.48), was used. In two-thirds of the observations the lowest 5-min values of Vo2 did not represent the true basal metabolic rate of the animal since they coincided with variable amounts of spontaneous activity. Data show that the basal metabolic rate of the albino rat is more predictable than generally admitted. Submitted on May 26, 1961


1971 ◽  
Vol 72 (5) ◽  
pp. 1266-1268
Author(s):  
A. S. Saratikov ◽  
T. A. Revina ◽  
A. I. Ryzhov ◽  
B. Yu. Sal'nik

1977 ◽  
Vol 47 (2) ◽  
pp. 241-251 ◽  
Author(s):  
Bengt Nilsson ◽  
Urban Pontén ◽  
Gerhard Voigt

✓ Impact acceleration was used to elicit cerebral concussion in the albino rat. The pathophysiological response and morphological damage from the concussion were studied in groups of animals. The animals were grouped according to impact velocity (6–11 m/sec), and the threshold and different degrees of the concussive response were established. The concept of concussion as primarily a neuronal, functional disturbance was confirmed. However, this reaction was readily influenced by respiratory and circulatory changes, and morphological damage. Defined reactions could be elicited in groups of animals according to impact velocity. Thus, the model appeared well standardized for further studies of concussion pathophysiology, expressed in terms of cerebral energy metabolism and blood flow.


Author(s):  
R. Carriere

The external orbital gland of the albino rat exhibits both sexual dimorphism and histological age changes. In males, many cells attain a remarkable degree of polyploidy and an increase of polyploid cell number constitutes the major age change until young adulthood. The acini of young adults have a small lumen and are composed of tall serous cells. Subsequently, many acini acquire a larger lumen with an irregular outline while numerous vacuoles accumulate throughout the secretory cells. At the same time, vesicular acini with a large lumen surrounded by pale-staining low cuboidal diploid cells begin to appear and their number increases throughout old age. The fine structure of external orbital glands from both sexes has been explored and in considering acinar cells from males, emphasis was given to the form of the Golgi membranes and to nuclear infoldings of cytoplasmic constituents.


Author(s):  
W.A. Jacob ◽  
R. Hertsens ◽  
A. Van Bogaert ◽  
M. De Smet

In the past most studies of the control of energy metabolism focus on the role of the phosphorylation potential ATP/ADP.Pi on the regulation of respiration. Studies using NMR techniques have demonstrated that the concentrations of these compounds for oxidation phosphorylation do not change appreciably throughout the cardiac cycle and during increases in cardiac work. Hence regulation of energy production by calcium ions, present in the mitochondrial matrix, has been the object of a number of recent studies.Three exclusively intramitochondnal dehydrogenases are key enzymes for the regulation of oxidative metabolism. They are activated by calcium ions in the low micromolar range. Since, however, earlier estimates of the intramitochondnal calcium, based on equilibrium thermodynamic considerations, were in the millimolar range, a physiological correlation was not evident. The introduction of calcium-sensitive probes fura-2 and indo-1 made monitoring of free calcium during changing energy metabolism possible. These studies were performed on isolated mitochondria and extrapolation to the in vivo situation is more or less speculative.


1969 ◽  
Author(s):  
Leland E. Rhodes ◽  
Donovan E. Fleming
Keyword(s):  

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