Thermally induced peripheral blood flow changes in chickens

1978 ◽  
Vol 44 (1) ◽  
pp. 81-84 ◽  
Author(s):  
W. F. Nolan ◽  
W. W. Weathers ◽  
P. D. Sturkie

Changes in wattle blood flow (Q) and vascular resistance (R) were examined during both local heating of the wattle and/or general body heating of unanesthetized, male White Leghorn chickens. Q increased and R decreased during both local and general heating. Termination of heating reversed the response. Beta stimulation with isoproterenol markedly reduced R and increased Q in normothermic birds, suggesting the presence of beta receptors in the wattle vasculature. Alpha blockade with phenoxybenzamine also resulted in pronounced vasodilatation, suggesting tonic alpha-sympathetic tone in the wattle vasculature under normothermic conditions. Neither cholinergic blockade with atropine sulfate nor beta-adrenergic blockade with propranolol altered the vascular response to general heating when administered near its peak. Release of alpha-sympathetic tone is believed to subserve the response to general heating.

1982 ◽  
Vol 52 (1) ◽  
pp. 16-20 ◽  
Author(s):  
C. K. Chapler ◽  
S. M. Cain

Studies were carried out in seven anesthetized paralyzed dogs to examine the importance of alpha -adrenergic tone in the cardiovascular responses during acute anemia. Data were obtained 1) at normal hematocrit (Hct), 2) during anemia produced by isovolemic hemodilution with dextran (Hct, 13–15%), 3) during anemia after alpha -blockade (alpha -bl) with phenoxybenzamine (3 mg/kg), and 4) following volume expansion during anemia with a red blood cell dextran solution. Cardiac output (QT), limb and total body oxygen uptake (VO2), and limb blood flow (QL) were determined. Both QT and QL increased during anemia (P less than 0.01), whereas limb resistance (RL) and total peripheral resistance (TPR) were decreased (P less than 0.01). No further change in either RL or TPR occurred with alpha -blockade anemia, but both QT and QL decreased (P less than 0.01). Whole-body VO2 increased during anemia and then declined with alpha -bl and anemia. Following volume expansion during anemia with alpha -bl, QT, QL, and whole-body VO2 increased. We conclude that alpha -adrenergic sympathetic tone to capacitance vessels is essential for the cardiac output increased during anemia, but has little or no effect on resistance vessels and hence distribution of peripheral blood flow.


Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1036
Author(s):  
Kristina Norvilaitė ◽  
Diana Ramašauskaitė ◽  
Daiva Bartkevičienė ◽  
Bronius Žaliūnas ◽  
Juozas Kurmanavičius

Background and Objectives: Intrauterine growth restriction (IUGR) is the term used to describe a fetus whose estimated weight is less than the 10th percentile of its age growth curve. IUGR is the second most common cause of perinatal death. In many cases there is a deficiency in the standardization of optimal management, prenatal follow-up and timing of delivery. Doppler examination is the most sensitive test that can assess the condition of the fetus and indicate fetal intrauterine hypoxia. Numerous studies of the fetal intrauterine state focus on the umbilical artery and the fetal cerebral blood vessels, while the peripheral arteries have so far received insufficient attention. Materials and Methods: We present a case of an IUGR fetus monitored with a non-stress test (NST) and a Doppler examination of the fetal arteries (tibial, umbilical, middle cerebral and uterine) and the ductus venosus. In this case the first early sign of fetal hypoxia was revealed by blood flow changes in the tibial artery. Results: We hypothesize that peripheral vascular changes (in the tibial artery) may more accurately reflect the onset of deterioration in the condition of the IUGR fetus, such that peripheral blood flow monitoring ought to be employed along with other techniques already in use. Conclusion: This paper describes the clinical presentation of an early detection of late IUGR hypoxia and claims that blood flow changes in the tibial artery signal the worsening of the fetus’s condition.


1972 ◽  
Vol 80 (3) ◽  
pp. 312-323 ◽  
Author(s):  
Lawrence A. Baker ◽  
Wesley W. Weathers ◽  
Fred N. White

1991 ◽  
Vol 69 (10) ◽  
pp. 1399-1404 ◽  
Author(s):  
P. Kubes ◽  
K. A. Nesbitt ◽  
S. M. Cain ◽  
C. K. Chapler

We questioned whether carbon monoxide hypoxia (COH) would affect peripheral blood flow by neural activation of adrenoceptors to the extent we had found in other forms of hypoxia. We studied this problem in hindlimb muscles of four groups of anesthetized dogs (untreated, α1-blocked, α1 + α2-blocked, and β2-blocked). Cardiac output increased, but hindlimb blood flow [Formula: see text] and resistance (RL) remained at prehypoxic levels during COH (O2 content reduced 50%) in untreated animals. When activity in the sciatic nerve was reversibly cold blocked, [Formula: see text] doubled and RL decreased 50%. These changes with nerve block were the same during COH, suggesting that neural activity to hindlimb vasculature was not increased by COH. In animals treated with phenoxybenzamine (primarily α1-blocked), RL dropped (~50%) during COH, an indication that catecholamines played a significant role in maintaining tone to skeletal muscle. Animals with both α1 + α2-adrenergic blockade (phenoxybenzamine and yohimbine added) did not survive COH. RL was higher in β2-block than in the untreated group during COH, but nerve cooling indicated that β2-adrenoceptor vasodilation was accomplished primarily by humoral means. The above findings demonstrated that adrenergic receptors were important in the regulation of [Formula: see text] and RL during COH, but they were not activated by sympathetic nerve stimulation to the limb muscles.Key words: α1-adrenoreceptor blockade, α2-adrenoreceptor blockade, peripheral vascular resistance, skeletal muscle, blood flow.


2020 ◽  
Vol 125 (11) ◽  
pp. 1725-1731
Author(s):  
Mary Rezk-Hanna ◽  
Michael D. Nelson ◽  
Florian Rader ◽  
Neal L. Benowitz ◽  
Ryan Rosenberry ◽  
...  

2017 ◽  
Vol 24 (4) ◽  
pp. e12350 ◽  
Author(s):  
Eric Rivas ◽  
Serina J. McEntire ◽  
David N. Herndon ◽  
Ronald P. Mlcak ◽  
Oscar E. Suman

2015 ◽  
Vol 50 (10) ◽  
pp. 1069-1075 ◽  
Author(s):  
Kirsty A. Woodward ◽  
Vish Unnithan ◽  
Nicola D. Hopkins

Context Kinesiology tape (KT) has become popular among athletes for both injury prevention and rehabilitation due to its reported therapeutic effects, including facilitation of lymphatic flow and enhanced peripheral blood flow. However, evidence to support such claims is insufficient. Objective To determine whether KT improves skin blood flow (SkBF) responses in young, elite soccer players. Design Randomized crossover study. Setting Research laboratory. Patients or Other Participants Thirteen healthy, elite, adolescent male soccer players (age = 14.7 ± 0.6 years). Intervention(s) Participants completed 2 experimental trials; during trial 1, the volar aspect of the dominant forearm was taped. Forearm SkBF was measured within the taped area and 3 cm lateral to the taped area. During trial 2, no tape was applied to either site. Both trials were performed within 7 days. Main Outcome Measure(s) Baseline and maximal thermally (42°C) stimulated SkBF responses were assessed using laser Doppler flowmetry. Continuously measured SkBF and derived mean arterial pressure obtained at 5-minute intervals were used to calculate cutaneous vascular conductance (CVC), the primary outcome measure. Results No differences were observed for baseline SkBF or CVC between trials or measurement sites. After local heating, no differences were evident for SkBF or CVC between trials or measurement sites. Conclusions Our findings suggest that, in healthy, trained adolescent males, KT was not associated with increased forearm SkBF.


2016 ◽  
Vol 38 (1) ◽  
pp. 46-55 ◽  
Author(s):  
Hui C. Choo ◽  
Kazunori Nosaka ◽  
Jeremiah J. Peiffer ◽  
Mohammed Ihsan ◽  
Chow C. Yeo ◽  
...  

EP Europace ◽  
2006 ◽  
Vol 8 (1) ◽  
pp. 44-50 ◽  
Author(s):  
Panayota Flevari ◽  
George Theodorakis ◽  
Ioannis Paraskevaidis ◽  
Fotis Kolokathis ◽  
Anna Kostopoulou ◽  
...  

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