scholarly journals Isolation of Klebsiella Pneumoniae from an Hepatic Inflammatory Pseudotumour

1992 ◽  
Vol 6 (2) ◽  
pp. 84-86 ◽  
Author(s):  
Dickran K Malatjalian ◽  
John Morris ◽  
Audley Bodurtha
Keyword(s):  
Klebsiella Pneumoniae ◽  
Tissue Response ◽  
Low Grade ◽  
Solid Mass ◽  
Inflammatory Pseudotumour ◽  
First Case ◽  
Mass Lesions ◽  
Inflammatory Tissue

lnflammatory pseudotumours of the liver are rare, solid mass lesions (often mistaken for malignancy) and although inflammatory in nature, are obscure in etiology and pathogenesis. An hepatic inflammatory pseudotumour is presented in which cultures obtained from the lesion intraoperatively grew Klebsiella pneumoniae. This is the first case of an hepatic inflammatory pseudotumour in which a microorganism has been identified. The isolation of K pneumoniae suggests that inflammatory pseudotumours may arise from a low grade infection with chronic inflammatory tissue response.

scholarly journals Microbiome and PCOS: State-of-Art and Future Aspects

2021 ◽  
Vol 22 (4) ◽  
pp. 2048
Author(s):  
Pierluigi Giampaolino ◽  
Virginia Foreste ◽  
Claudia Di Filippo ◽  
Alessandra Gallo ◽  
Antonio Mercorio ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Bile Acid ◽  
Peptide Yy ◽  
Fecal Microbiota Transplantation ◽  
Polycystic Ovary ◽  
Current Evidence ◽  
Low Grade ◽  
Fecal Transplant ◽  
Secondary Bile Acid ◽  
First Case

Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease. The hypothesis that alterations in the microbiome are involved in the genesis of PCOS has been postulated. Aim of this review is to summarize the available literature data about the relationship between microbiome and PCOS. A search on PubMed and Medline databases was performed from inception to November 20Most of evidence has focused on the connection of intestinal bacteria with sex hormones and insulin-resistance: while in the first case, a relationship with hyperandrogenism has been described, although it is still unclear, in the second one, chronic low-grade inflammation by activating the immune system, with increased production of proinflammatory cytokines which interfere with insulin receptor function, causing IR (Insulin Resistance)/hyperinsulinemia has been described, as well as the role of gastrointestinal hormones like Ghrelin and peptide YY (PYY), bile acids, interleukin-22 and Bacteroides vulgatus have been highlighted. The lower genital tract microbiome would be affected by changes in PCOS patients too. The therapeutic opportunities include probiotic, prebiotics and synbiotics, as well as fecal microbiota transplantation and the use of IL-22, to date only in animal models, as a possible future drug. Current evidence has shown the involvement of the gut microbiome in PCOS, seen how humanized mice receiving a fecal transplant from women with PCOS develop ovarian dysfunction, immune changes and insulin resistance and how it is capable of disrupting the secondary bile acid biosynthesis. A future therapeutic approach for PCOS may involve the human administration of IL-22 and bile acid glycodeoxycholic acid.

Low-Grade Mucosa-Associated Lymphoid Tissue Lymphoma Involving the Kidney: Report of 3 Cases and Review of the Literature

2006 ◽  
Vol 130 (1) ◽  
pp. 86-89 ◽  
Author(s):  
Libo Qiu ◽  
Pamela D. Unger ◽  
Robert W. Dillon ◽  
James A. Strauchen
Keyword(s):  
Lymphoid Tissue ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Lymphoid Cells ◽  
Low Grade ◽  
The Third ◽  
First Case ◽  
Abundant Cytoplasm ◽  
History Of

Abstract Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue involving the kidney is rare. We report a series of 3 cases. The first case occurred in an 83-year-old woman who presented with back pain. The second case was a 53-year-old man with a history of sarcoidosis who was found, in the course of evaluation of sarcoidosis, to have a right renal mass. The third case occurred in a 72-year-old man who had a history of periorbital mucosa–associated lymphoid tissue lymphoma and had been treated with surgery and radiation 1 year prior to this presentation. Histologically, all 3 patients showed infiltrate of uniform small-to-medium–sized lymphocytes with irregular nuclear contours and abundant cytoplasm resembling centrocytes or monocytoid lymphoid cells. The first patient received chemotherapy without complications. The second patient underwent a partial nephrectomy and was asymptomatic at the subsequent follow-up. The third patient developed a pulmonary embolism following nephrectomy, and further follow-up is not available.

scholarly journals Langerhans Cell Histiocytosis with Isolated Central Diabetes Insipidus, Low Grade Fever and Sellar Erosion

2021 ◽  
Author(s):  
İclal Okur ◽  
Hasan Ari ◽  
Semra Çetinkaya ◽  
Betül Emine Derinkuyu ◽  
Gizem Çağlar ◽  
...  
Keyword(s):  
Diabetes Insipidus ◽  
Langerhans Cell Histiocytosis ◽  
Bone Structure ◽  
Sella Turcica ◽  
Langerhans Cell ◽  
Central Diabetes Insipidus ◽  
Bone Lesions ◽  
Warning Sign ◽  
Low Grade ◽  
First Case

Langerhans cell histiocytosis (LCH) is a rare disease of the monocyte-macrophage system. Although it is known that bone involvement is seen very frequently in cases with LCH, our case is the first case with a lytic-destructive lesion in the bone structure forming sella turcica. A 4-year-old, 5-month-old male patient who applied to our outpatient clinic was diagnosed with Langerhans cell histiocytosis in further examination after the diagnosis of central diabetes insipidus (CDI) was made. On cranial magnetic resonance imaging (MRI), widespread lytic-destructive bone lesions were observed in the bone structure forming the sella (sphenoid bone), sellar destruction not previously described in the literature. Sellar erosion has not been reported before in cases diagnosed with LCH in the literature. The presence of low-grade fever in a patient presenting with isolated CDI is a warning sign for the diagnosis of LCH.

scholarly journals A comparative Histologic and Immunohistochemistry Evaluation Between Normal Aponeurotic Tissue, Fibrotic Aponeurotic Scars and Polypropylene Embedded Aponeurotic Scars

2017 ◽  
Vol 54 (3) ◽  
pp. 510-512
Author(s):  
Radu Chicea ◽  
Dan Bratu ◽  
Anca Lucia Chicea ◽  
Alin Mihetiu ◽  
Vlad Preluca ◽  
...  
Keyword(s):  
Urinary Incontinence ◽  
Stress Urinary Incontinence ◽  
Prognostic Marker ◽  
Genital Prolapse ◽  
Tissue Response ◽  
Surgical Interventions ◽  
Inflammatory Tissue

Synthetic polypropylene materials are increasingly being used in surgery to repair parietal defects in perineal floor curing surgery, in genital prolapse and stress urinary incontinence. The tissue response to contact with these materials varies, and the inflammatory tissue response may be a prognostic marker of success in surgical interventions that involve contact between tissues and polypropylene materials.

scholarly journals Large Vallecular Masses; Differential Diagnosis and Imaging Features

2018 ◽  
Vol 8 ◽  
pp. 26 ◽  
Author(s):  
Ashim Kumar Lahiri ◽  
Krishna Kiran Somashekar ◽  
Bernd Wittkop ◽  
Christopher Ayshford
Keyword(s):  
Differential Diagnosis ◽  
Wide Spectrum ◽  
Tongue Base ◽  
Low Grade ◽  
Imaging Features ◽  
Disease Entity ◽  
Palatine Tonsils ◽  
Uncommon Disease ◽  
Mass Lesions ◽  
Supraglottic Larynx

Large vallecular masses are an uncommon disease entity which includes a wide spectrum of rare pathologies. These masses may present as purely vallecular in location or appear as an extension from adjacent anatomical sites like tongue base including lingual tonsils, epiglottis, palatine tonsils, epiglottis, and the remainder of supraglottis. Literature review reveals very rare conditions presenting as vallecular mass lesions. The imaging features are generally diagnostic for characterization. However, these masses can exhibit indeterminate appearance at imaging. We present a series of five cases which includes two rare presentations: a case of low-grade cribriform adenocarcinoma of the base of tongue and a vallecular lipoma. The other three cases presented for differential diagnosis including benign vallecular cysts and two cases to show that malignant masses arising from neighboring anatomical sites such as tongue base or supraglottic larynx can exhibit significant vallecular component.

scholarly journals Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Gene M. Weinstein ◽  
Knarik Arkun ◽  
James Kryzanski ◽  
Michael Lanfranchi ◽  
Gaurav K. Gupta ◽  
...  
Keyword(s):  
Back Pain ◽  
Case Report ◽  
Lower Back Pain ◽  
Low Grade ◽  
Review Of The Literature ◽  
Pathologic Evaluation ◽  
Lower Back ◽  
Spinal Lesions ◽  
First Case ◽  
Intradural Extramedullary

Ependymomas are common spinal lesions, with the vast majority arising in an intramedullary location. Several cases have been described in the literature of ependymomas in an intradural, extramedullary location. The authors present a case of a 56-year-old female who presented with several weeks of lower back pain and weakness. MRI revealed an intradural, extramedullary enhancing mass at L1-L2. The mass was successfully resected surgically. Pathologic evaluation revealed a low grade glioma with components of both ependymoma and pilocytic astrocytoma with MUTYH G382D mutation. Extramedullary ependymomas are very rare tumors. To the authors’ knowledge, this is the first case of ependymoma/astrocytoma collision tumors described in an extramedullary location.

Multi-Objective Optimization of a Combined Power and Cooling Cycle for Low-Grade and Midgrade Heat Sources

2012 ◽  
Vol 134 (3) ◽  
Author(s):  
Gokmen Demirkaya ◽  
Saeb Besarati ◽  
Ricardo Vasquez Padilla ◽  
Antonio Ramos Archibold ◽  
D. Yogi Goswami ◽  
...  
Keyword(s):  
Thermodynamic Cycle ◽  
Solution Concentration ◽  
Working Fluid ◽  
Low Grade ◽  
Basic Solution ◽  
Heat Sources ◽  
Fluid Mixture ◽  
Cooling Cycle ◽  
Multi Objective ◽  
First Case

Optimization of thermodynamic cycles is important for the efficient utilization of energy sources; indeed, it is more crucial for the cycles utilizing low-grade heat sources where the cycle efficiencies are smaller compared to high temperature power cycles. This paper presents the optimization of a combined power/cooling cycle, also known as the Goswami cycle, which combines the Rankine and absorption refrigeration cycles. The cycle uses a special binary fluid mixture as the working fluid and produces a power and refrigeration. In this regard, multi-objective genetic algorithms (GAs) are used for Pareto approach optimization of the thermodynamic cycle. The optimization study includes two cases. In the first case, the performance of the cycle is evaluated as it is used as a bottoming cycle and in the second case, as it is used as a top cycle utilizing solar energy or geothermal sources. The important thermodynamic objectives that have been considered in this work are, namely, work output, cooling capacity, effective first law, and exergy efficiencies. Optimization is carried out by varying the selected design variables, such as boiler temperature and pressure, rectifier temperature, and basic solution concentration. The boiler temperature is varied between 70–150 °C and 150–250 °C for the first and the second cases, respectively.

Disrupting the right pars opercularis with electrical stimulation frees the song: case report

2015 ◽  
Vol 123 (6) ◽  
pp. 1401-1404 ◽  
Author(s):  
Guillaume Herbet ◽  
Gilles Lafargue ◽  
Fabien Almairac ◽  
Sylvie Moritz-Gasser ◽  
François Bonnetblanc ◽  
...  
Keyword(s):  
Language Production ◽  
Inferior Frontal Gyrus ◽  
Awake Surgery ◽  
Low Grade ◽  
Speech Impairment ◽  
First Case ◽  
Pars Opercularis ◽  
The Right

The authors report the first case of a strikingly unusual speech impairment evoked by intraoperative electrostimulation in a 36-year-old right-handed patient, a well-trained singer, who underwent awake surgery for a right fronto-temporo-insular low-grade glioma. Functionally disrupting the pars opercularis of the right inferior frontal gyrus led the patient to automatically switch from a speaking to a singing mode of language production. Given the central role of the right pars opercularis in the inhibitory control network, the authors propose that this finding may be interpreted as possible evidence for a competitive and independent neurocognitive subnetwork devoted to the melodically intoned articulation of words (normal language-based vs singing-based) in subjects with high expertise. From a more clinical perspective, such data may have implications for awake neurosurgery, especially to preserve the quality of life for singers.

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