scholarly journals Sensorineural Hearing Loss and Celiac Disease: A Coincidental Finding

2009 ◽  
Vol 23 (8) ◽  
pp. 531-535 ◽  
Author(s):  
Umberto Volta ◽  
Gian Gaetano Ferri ◽  
Roberto De Giorgio ◽  
Angela Fabbri ◽  
Claudia Parisi ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Celiac Disease ◽  
Sensorineural Hearing Loss ◽  
Neurological Diseases ◽  
Clinical Signs ◽  
Hashimoto Thyroiditis ◽  
Sensorineural Hearing ◽  
Immune Markers ◽  
Antineuronal Antibodies ◽  
Hearing Function

BACKGROUND: Celiac disease (CD) can be associated with a variety of extraintestinal manifestations, including neurological diseases. A new neurological correlation has been found between CD and sensorineural hearing loss (SNHL).OBJECTIVE: To verify the association between SNHL and CD, and to establish whether the neurological hearing impairment in CD is related to nonorgan-specific and antineuronal antibodies, as well as the presence of autoimmune disorders.METHODS: A sample of 59 consecutive biopsy- and serologically proven CD patients were studied. Among CD patients, 11 were newly diagnosed and 48 were on a gluten-free diet. Hearing function was assessed by audiometric analysis in all CD patients as well as in 59 age- and sex-matched controls. Patients were tested for a panel of immune markers including nonorgan-specific autoantibodies and antineuronal antibodies.RESULTS: SNHL was detected in five CD patients (8.5%) and in two controls (3.4%). In one patient, the SNHL was bilateral, whereas the remaining four had a monolateral impairment. The prevalence of SNHL was not significantly different between CD patients and controls. At least one of the antibodies tested for was positive in two of the five CD patients with SNHL and in 12 of the 54 CD patients without SNHL. Antineuronal antibodies to central nervous system antigens were consistently negative in the five CD patients with SNHL. Only one of the five CD patients with SNHL had Hashimoto thyroiditis.CONCLUSIONS: SNHL and CD occur coincidentally. Hearing function should be assessed only in CD patients with clinical signs of hearing deficiency.

scholarly journals Clinical Profile and Outcome of Acute Encephalitis Syndrome in Dhulikhel Hospital of Nepal

2013 ◽  
Vol 32 (3) ◽  
pp. 201-205 ◽  
Author(s):  
Srijana Dongol ◽  
Shreema Shrestha ◽  
Narayan Shrestha ◽  
J Adhikari
Keyword(s):  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Clinical Signs ◽  
Viral Meningitis ◽  
Sensorineural Hearing ◽  
Subdural Effusion ◽  
Eosinophilic Meningitis ◽  
Acute Encephalitis Syndrome ◽  
Acute Encephalitis

Introduction: Acute encephalitis syndrome (AES) is a constellation of clinical signs and or symptoms i.e. acute fever with acute change in mental status. AES may be present as encephalitis, meningoencephalitis or meningitis. It can be associated with severe complication, including impaired consciousness, seizure, limb paresis or death. Materials and Methods: Study consisted of retrospective analysis of hospital records of children up to 16 years of age admitted with diagnosis of AES in the department of Paediatrics Dhulikhel Hospital, Kathmandu University Teaching Hospital, Dhulikhel Kavre from January 2010 to December 2011. Results: During the two years (January 2010 to December 2011), 47 patients of AES were admitted. Among the admitted cases there were 34 male and 13 female patients. Meningitis cases were 29, encephalitis cases were 14 and 4 meningoencephalitis cases. Among the meningitis cases, viral meningitis accounted for 12, bacterial meningitis accounted for 15 and 1 tubercular meningitis.One was eosinopilic meningitis in which the causative organism was found to be fasciolosis by ELISA. Viral encephalitis was found to be the most common cause of encephalitis. Sensorineural hearing loss was seen in 3 cases, subdural effusion in 1 and hydrocephalus in 1. One patient had intracranial hemorrhage with hemiparesis as a complication of eosinophilic meningitis. Conclusion: Acute encephalitis syndrome is one of the most common causes of PICU admission in Dhulikhel hospital. Bacterial meningitis was common among the acute encephalitis syndrome followed by viral meningitis. One case of eosinophilic meningitis with intracranical hemorrhage and hemiparesis was found. Sensorineural hearing loss was found to be commonest complication. DOI: http://dx.doi.org/10.3126/jnps.v32i3.6683 J. Nepal Paediatr. SocVol.32(3) 2012 201-205

scholarly journals ENT Manifestations of Celiac Disease: A Scholarly Review

2020 ◽  
pp. 014556132097260
Author(s):  
Dilhara Karunaratne ◽  
Nisal Karunaratne
Keyword(s):  
Obstructive Sleep Apnea ◽  
Hearing Loss ◽  
Celiac Disease ◽  
Sleep Apnea ◽  
Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Septal Perforation ◽  
Nasal Septal Perforation ◽  
Obstructive Sleep ◽  
Pubmed Database

Objectives: Celiac disease is a common multisystemic autoimmune disorder. It is now increasingly recognized that it may present with extraintestinal manifestations which contribute to the difficulty in its diagnosis. The objective of this scholarly review was to examine the extraintestinal ENT manifestations of celiac disease and its pathophysiology and management, in order to highlight that some patients with celiac disease may present initially to the otolaryngologist. Improving awareness of celiac disease among otolaryngologists may aid in the correct diagnosis and correct management plan. Methods: A literature review was conducted using the PubMed database to identify original articles related to celiac disease and ENT manifestations between the years 2000 and 2020. The search was performed using the search string: (“coeliac disease” OR “celiac disease”) AND (“ENT manifestations” OR “hearing loss” OR “epistaxis” OR “nasal septal perforation” OR “obstructive sleep apnoea” OR “vertigo” OR “tonsillitis” OR “sinusitis”). Only articles written in English were reviewed. Results: A total of 17 papers met the inclusion criteria. Extraintestinal ENT manifestations of celiac disease include sensorineural hearing loss, obstructive sleep apnea, nasal septal perforation, epistaxis, and vertigo with nystagmus. Sensorineural hearing loss, obstructive sleep apnea, nasal septal perforation, vertigo, and nystagmus are thought to result from immunologically mediated mechanisms, with intestinal malabsorption resulting in epistaxis. Conclusions: Celiac disease can cause extraintestinal ENT manifestations and requires a high index of suspicion from the otolaryngologist to diagnose and suitably manage. A gluten-free diet may result in sufficient symptom resolution for most manifestations. Sensorineural hearing loss due to celiac disease appears to be progressive and permanent and may require frequent audiological monitoring.

scholarly journals Does celiac disease cause autoimmune sensorineural hearing loss?

2019 ◽  
Vol 30 (9) ◽  
pp. 776-781 ◽  
Author(s):  
Alper Yazici ◽  
◽  
Abdullah Emre Yildirim ◽  
Bugra Tolga Konduk ◽  
◽  
...  
Keyword(s):  
Hearing Loss ◽  
Celiac Disease ◽  
Sensorineural Hearing Loss ◽  
Sensorineural Hearing

scholarly journals Risk Factors for Hearing Loss in Children following Bacterial Meningitis in a Tertiary Referral Hospital

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Benson Wahome Karanja ◽  
Herbert Ouma Oburra ◽  
Peter Masinde ◽  
Dalton Wamalwa
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Bacterial Meningitis ◽  
Sensorineural Hearing Loss ◽  
Healthcare Providers ◽  
Sensorineural Hearing ◽  
Tertiary Referral Hospital ◽  
Hearing Function ◽  
Children With Hearing Loss ◽  
Audiologic Testing

Objective. This study aimed to examine hearing function in children admitted with bacterial meningitis to determine the risk factors for sensorineural hearing loss.Setting. The study was conducted in the audiology unit and paediatric wards of Kenyatta National Hospital.Subjects and Methods. The study involved 83 children between the ages of six months and twelve years admitted with bacterial meningitis. The median age for the children examined was 14. On discharge they underwent hearing testing to evaluate for presence and degree of hearing loss.Results. Thirty six of the 83 children (44.4%) were found to have at least a unilateral mild sensorineural hearing loss during initial audiologic testing. Of the children with hearing loss, 22 (26.5%) had mild or moderate sensorineural hearing loss and 14 (16.9%) had severe or profound sensorineural hearing loss. Significant determinants identified for hearing loss included coma score below eight, seizures, cranial nerve neuropathy, positive CSF culture, and fever above 38.7 degrees Celsius.Conclusions. Sensorineural hearing loss was found to be highly prevalent in children treated for bacterial meningitis. There is need to educate healthcare providers on aggressive management of coma, fever, and seizures due to their poor prognostic value on hearing.

Zika Virus Infection during Pregnancy and Sensorineural Hearing Loss among Children at 3 and 24 Months Post-Partum

2018 ◽  
Vol 65 (4) ◽  
pp. 328-335 ◽  
Author(s):  
Marcela Fandiño-Cárdenas ◽  
Alvaro J Idrovo ◽  
Roman Velandia ◽  
Jessica Molina-Franky ◽  
Jorge L Alvarado-Socarras
Keyword(s):  
Hearing Loss ◽  
High Risk ◽  
Sensorineural Hearing Loss ◽  
Post Partum ◽  
Clinical Signs ◽  
Sensorineural Hearing ◽  
Zikv Infection ◽  
Distortion Product ◽  
Epidemic Period ◽  
Brainstem Response

Abstract Objective The objectives of this study were to describe the findings of the auditory screening in children of mothers with ZIKV during pregnancy or suspicious of congenital ZIKV, and to determine whether hearing loss was in the first 2 years in life, regardless of whether microcephaly was also present. Methods This is a cases report. The information was collected and recorded in a database between January 2016 and April 2018. We perform two auditory tests to 3 and 24 months of life. The study was developed in Aguachica (Cesar, Colombia). It is considered a high-risk area for ZIKV infection. Participants included children of mothers with confirmed ZIKV during pregnancy or suspicious of congenital ZIKV exposure of ZIKV infection during an epidemic period in a tropical area. We defined a positive case according to the epidemiological definition and clinical criteria based on maternal symptoms. However, other children of mothers without clinical signs of Zika were evaluated at the same time. The main outcome was the presence of sensorineural hearing loss. Results The median age in the study group (n = 43) was 3.5 months (rank: 0–6) and the comparison group (n: 23, children of mothers without clinical signs of ZIKV) was 3 months (rank: 0–12). Screening hearing test was done using distortion product otoacustic emissions. At 3 months follow-up, children were evaluated using distortion product otoacustic emissions and automatized auditory brainstem response. None of the patients evaluated in this study were found to have sensorineural hearing loss. Conclusions We did not find hearing loss during the first 2 years in the children whose mother showed Zika during pregnancy. We recommend these children must be assessed to closed because there is a high risk the hearing loss as it usually may occur with CMV.

scholarly journals Sudden sensorineural hearing loss: Is there a connection with inner ear electrolytic disorders? A literature review

2016 ◽  
Vol 29 (4) ◽  
pp. 595-602 ◽  
Author(s):  
Andrea Ciorba ◽  
Virginia Corazzi ◽  
Chiara Bianchini ◽  
Claudia Aimoni ◽  
Henryk Skarzynski ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Inner Ear ◽  
Otoacoustic Emissions ◽  
Cell Function ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
Electrolyte Disorders ◽  
Hearing Function ◽  
Normal Hair

Electrolytic disorders of the inner ear represent a model that could be implicated in partially explaining the pathogenesis of sudden sensorineural hearing loss (SSNHL). Different types of electrolytes and different inner-ear loci are involved in cochlear homeostasis physiologically, to ensure the maintenance of an ion-balanced cochlear environment allowing a normal hair cell function. It has been hypothesized that a sudden loss of endocochlear potential, due to a rapid disruption of the inner ear fluid osmolality, could be responsible for a deterioration of the hearing function caused by damaged hair cells. The aim of this paper was to review the current literature and identify sources which might validate/fortify the hypothesis that inner ear electrolytic disorders have a role in the etiopathogenesis of SSNHL. The data in the literature underline the importance of ionic homeostasis in the inner ear, but they do not support a direct link between SSNHL and electrolyte disorders/imbalances. There is marginal evidence from otoacoustic emissions research that an indirect link might be present.

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