scholarly journals Arthralgia and Osteolytic Lesions Associated with Traumatic Pancreatitis in a 10-Year-Old Girl

2009 ◽  
Vol 2009 ◽  
pp. 1-3
Author(s):  
Masayuki Obatake ◽  
Yusuke Yamane ◽  
Takayuki Tokunaga ◽  
Yasuaki Taura ◽  
Yukio Inamura ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Joint Pain ◽  
Serum Amylase ◽  
Knee Joints ◽  
Pancreatic Pseudocysts ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Osteolytic Lesions ◽  
Pseudocyst Drainage ◽  
Traumatic Pancreatitis

A case of traumatic pancreatitis with subsequent joint pain and osteolytic lesions is presented. A 10-year-old girl was admitted to our hospital with abdominal pain caused by blunt epigastric injury. She was diagnosed with traumatic pancreatitis, and multiple pancreatic pseudocysts subsequently developed. Two weeks after admission, she complained of joint pain, and MR revealed osteolytic lesions of both knee joints. On the 58th day, endoscopic transgastric pseudocyst drainage was performed. Joint pain and osteolytic lesions resolved rapidly, in parallel with the decrease in serum amylase level and pseudocyst size.

scholarly journals Routine Measurement of Serum Amylase in Acute Abdomen

2014 ◽  
Vol 52 (196) ◽  
pp. 982-985 ◽  
Author(s):  
Roshan Ghimire ◽  
Anurag Singh Thapa ◽  
Dimindra Karki ◽  
Dipendra Kumar Shrestha
Keyword(s):  
Emergency Department ◽  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Acute Abdomen ◽  
Serum Amylase ◽  
Acute Abdominal Pain ◽  
College Teaching ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Routine Measurement

Introduction: Acute abdominal pain is a common condition presenting to both the emergency department and surgical admission unit. Increase in serum amylase levels are found in much gastrointestinal pathology. Serum amylase level is consistently high in acute pancreatitis though high values are not pathognomonic of pancreatitis .The aim of this study to assess the level of serum amylase in various diseases presenting with acute abdominal pain and to evaluate the role of routine measurement of serum amylase in the screening of patient with acute abdominal pain for the diagnosis of acute pancreatitis in a prospective series. Methods: A prospective observational study was performed from 15th May 2014 – 15th Nov 2014 (6 months) at Department of Surgery of Kathmandu medical College Teaching Hospital; Kathmandu. All consecutive patients presented at emergency department and required admissions in surgical ward were included. A multivariate analysis was performed to assess the level of serum amylase in various diseases presenting with acute abdominal pain including acute pancreatitis. Results: Overall, 318 patients were included during a period of 6 months among them 48 patients were excluded. 34 cases (12.6 %) were diagnosed of acute pancreatitis. three cases (1.1%) of non pancreatic pathology with raised serum amylase level (> 1000 U\L). Conclusions: Routine assessment of serum amylase is helpful in excluding differential diagnosis of patient presenting with acute abdomen and this study identified serum amylase as a good screening tool if done in cases with clinical suspicion.  Keywords: acute abdominal pain; acute pancreatitis; serum amylase.

Pancreatic Pseudocysts in Ile-Ife, Nigeria: A Report of 6 Cases

1988 ◽  
Vol 18 (4) ◽  
pp. 163-166
Author(s):  
D O Akinola
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Serum Amylase ◽  
University Teaching ◽  
Teaching Hospitals ◽  
Pancreatic Pseudocysts ◽  
Internal Drainage ◽  
Presenting Symptoms ◽  
Barium Studies ◽  
University Teaching Hospitals

Pancreatic pseudocysts are uncommon and very few cases have been reported in Nigeria. Six cases of pancreatic pseudocysts were treated at Ife University Teaching Hospitals Complex from 1984 to 1986. The striking presenting symptoms were abdominal pain, nausea, vomiting and weight loss. Investigative procedures of serum amylase, barium studies and ultrasonography were performed. One resolved spontaneously, 5 patients had internal drainage and one of these died. The surviving patients are still being followed up.

scholarly journals Abdominal pain and a raised amylase? It’s not always pancreatitis…

2013 ◽  
Vol 12 (3) ◽  
pp. 163-165
Author(s):  
IO Oluwatowoju ◽  
◽  
EO Abu ◽  
G Lawson ◽  
◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Serum Amylase ◽  
Epigastric Pain ◽  
Elevated Serum ◽  
High Serum ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Heavy Alcohol ◽  
Heavy Alcohol Consumption ◽  
History Of

We report the case of a 72 year old man with a history of COPD and heavy alcohol consumption who was initially diagnosed with acute pancreatitis based on a presentation with epigastric pain and elevated serum amylase. Review of his notes revealed several previous similar admissions and extensive normal investigations apart from persistently elevated amylase. Further analysis showed evidence of macroamylasaemia which accounted for the apparently high serum amylase level.

scholarly journals Predictive value of serum amylase level in outcome of multiple trauma patients

2016 ◽  
Vol 4 (2) ◽  
pp. 115-121
Author(s):  
Arezu Nejabatian ◽  
Farzad Rahmani ◽  
Rozbeh Rajaei Ghafori ◽  
Samad Shams Vahdati ◽  
Parizad Varghayi ◽  
...  
Keyword(s):  
Multiple Trauma ◽  
Predictive Value ◽  
Serum Amylase ◽  
Amylase Level ◽  
Trauma Patients ◽  
Serum Amylase Level ◽  
Multiple Trauma Patients

scholarly journals AN ANALYSIS OF SERUM AMYLASE LEVEL IN CHOLELITHIASIS PATIENTS

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Anita Verma ◽  
Prerna Harsh
Keyword(s):  
Serum Amylase ◽  
Health Care Systems ◽  
Gallstone Disease ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Case Group ◽  
Amylase Level ◽  
Serum Amylase Level ◽  
Medical College ◽  
Care Systems

Background: Gallstone disease (GSD) is one of the most common gastrointestinal diseases. Gallstones represent a significant burden for health care systems worldwide and are one of the most common disorders presenting to emergency room. Methods: Hospital based case control study conducted at Department of Biochemistry with close collaboration of Department of General Surgery, S. P. Medical College and associated group of PBM Hospital, Bikaner, Rajasthan. Results: The insignificant serum amylase level difference in case group (47.80± 21.24) as compares to control group (45.97± 16.38). Conclusion: In this study comparison of amylase between case and controls group showed that the levels of amylase in cholelithiasis patients were higher than that of the control group, but there was no significant variation in amylase. Keywords: Amylase, cholelithiasis, Gallstone disease (GSD).

scholarly journals Three-hour post-ERCP amylase level: a useful indicator for early prediction of post-ERCP pancreatitis

2020 ◽  
Author(s):  
Ze-Hui Lv ◽  
Da-Qing Kou ◽  
Shi-Bin Guo
Keyword(s):  
Confidence Interval ◽  
Diagnostic Accuracy ◽  
Roc Curve ◽  
Predictive Value ◽  
Serum Amylase ◽  
Roc Curves ◽  
Amylase Level ◽  
Early Prediction ◽  
Serum Amylase Level ◽  
Significant Difference

Abstract Background: To evaluate the value of the 3-hour post-ERCP serum amylase level for early prediction of post-ERCP pancreatitis (PEP). Method: A study of 206 patients performed ERCP was analysed. The patients with PEP were recorded. ROC curves were used to statistically analyze the data. Results: PEP occurred in 21 patients (10.19%). The 3-hour post-ERCP pancreatic amylase level was used as the test variable, and the PEP occurrence as the state variable to plot ROC curve. The area under the curve (AUC) was 0.816 , and was statistically significant (P<0.001). The standard error (SE) was 0.0507, the 95% confidence interval (CI) was 0.756-0.866, and the optimal cut-off value was 351U/L (sensitivity 76.19%, specificity 83.24%, positive likelihood ratio 4.55, negative likelihood ratio 0.29, Youden index 59.43%). The ROC curves were plotted for both serum amylase and lipase respectively. The areas under the ROC curves were statistically significant(P<0.001). The area under the ROC curve for the 3-hour post-ERCP lipase was 0.778, the 95% confidence interval was 0.673-0.862, and optimal cut-off value was 1834 U/L. The area under the ROC curve for the 3-hour post-ERCP serum amylase was 0.780, and the 95% confidence interval was 0.676-0.864. The optimal cut-off is 380U/L, and there was no statistically significant difference between the two for diagnostic accuracy. According to gender, there was no statistically significant difference in the diagnostic accuracy. In the male group, 436 U/L serum amylase provided the greatest diagnostic accuracy with sensitivity(SE) of 70.5%, specificity(SP) of 89.2%, positive predictive value (PPV) 87.5%, and negative predictive value (NPV) 78.1%. Whereas, in the female group, 357U/L serum amylase provided the greatest diagnostic accuracy with sensitivity of 76.9%, specificity of 81.2%, positive predictive value of 80.4%, negative predictive value of 77.9%. Conclusions: 1. The 3-hour post-ERCP serum amylase level is a useful measurement for predicting post-ERCP pancreatitis. 2. There was no significant difference between serum amylase and lipase 3-hour post-ERCP for predicting PEP. 3. There was no statistically significant difference between male and female using the 3-hour post-ERCP serum amylase level to predict PEP. For female, the optimal cut-off value was 357 U/L, whereas male 436U/L .

scholarly journals PANCREATIC CANCER IN 31 YEARS OLD PATIENT WITH NORMAL SERUM AMYLASE LEVEL (Kanker Pankreas di Pasien Usia 31 Tahun dengan Kadar Amilase Serum Normal)

2018 ◽  
Vol 23 (1) ◽  
pp. 96
Author(s):  
Melda F. Flora ◽  
Budiono Raharjo ◽  
Maimun Z. Arthamin
Keyword(s):  
Serum Amylase ◽  
Normal Serum ◽  
Amylase Level ◽  
Gamma Glutamyl Transferase ◽  
Range Limit ◽  
Resonance Imaging ◽  
Serum Amylase Level ◽  
Magnetic Resonance Imaging Mri ◽  
Glutamyl Transferase ◽  
Tomography Scan

Kanker pankreas adalah keganasan sel di jaringan pankreas. kejadiannya meningkat pada usia di atas 60 tahun. Namun, sekitar20% dapat terjadi di usia muda. Patogenesis terjadinya masih belum jelas, dikemukakan bahwa mutasi genetik dan faktor eksogen sepertimerokok berhubungan dengan terjadinya keganasan sel pankreas. Kasus adalah seorang laki-laki perokok berusia 31 tahun dengankeluhan utama nyeri ulu hati menjalar ke punggung, disertai mual, muntah, nafsu makan turun. Pada pemeriksaan fisik didapatkansklera ikterik, perkusi redup dan ronkhi di paru, distensi abdomen dan asites. Pada pemeriksaan laboratorik didapatkan leukositosis,trombositopenia, peningkatan aspartate aminotransaminase (AST) lebih dari 10 kali Upper Range Limit (URL), hiperbilirubinemiadirek, peningkatan alkaline phosphatase (ALP), Gamma Glutamyl Transferase (GGT) dan lipase serum, sedangkan amilase serumnormal. Terdapat juga peningkatan kadar CA19-9. Pada computed tomography scan (CT scan) dan Magnetic Resonance Imaging (MRI)didapatkan gambaran kanker pankreas primer yang telah bermetastasis ke pleura dan hati. Kadar amilase normal di pasien dapatdisebabkan karena awal peningkatan dan penurunan kadar amilase terjadi lebih cepat dan pada saat diperiksa telah turun mencapaikadar normal. Simpulan, kanker pankreas dapat terjadi di usia muda. Amilase yang normal dapat terjadi di kanker pankreas.

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