scholarly journals Relationships between Obesity, Cardiorespiratory Fitness, and Cardiovascular Function

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Kade Davison ◽  
Stefan Bircher ◽  
Alison Hill ◽  
Alison M. Coates ◽  
Peter R. C. Howe ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiorespiratory Fitness ◽  
Arterial Compliance ◽  
Abdominal Fat ◽  
Whole Body ◽  
Metabolic Dysfunction ◽  
Body Fatness ◽  
Large Arteries ◽  
The Relationship ◽  
Cvd Mortality

Background. Obesity and low cardiorespiratory fitness (CRF) have been shown to independently increase the risk of CVD mortality. The aim of this study was to investigate the relationship between CRF, body fatness and markers of arterial function.Method and Results. Obese (9 male, 18 female; BMI 35.3 ± 0.9 kg·m-2) and lean (8 male, 18 female; BMI 22.5 ± 0.3 kg·m-2) volunteers were assessed for body composition (DXA), cardiorespiratory fitness (predicted max), blood pressure (BP), endothelial vasodilatator function (FMD), and arterial compliance (AC) (via radial artery tonometry). The obese group had more whole body fat and abdominal fat (43.5 ± 1.2% versus 27.2 ± 1.6%; and 48.6 ± 0.9% versus 28.9 ± 1.8%; resp.), and lower FMD (3.2 ± 0.4% versus 5.7 ± 0.7%; ) than the lean subjects, but there was no difference in AC. AC in large arteries was positively associated with CRF (; ) but not with fatness.Conclusion. These results indicate distinct influences of obesity and CRF on blood vessel health. FMD was impaired with obesity, which may contribute to arterial and metabolic dysfunction. Low CRF was associated with reduced elasticity in large arteries, which could result in augmentation of aortic afterload.

An evaluation of large arteries compliance in man

1979 ◽  
Vol 237 (5) ◽  
pp. H550-H554 ◽  
Author(s):  
A. C. Simon ◽  
M. E. Safar ◽  
J. A. Levenson ◽  
G. M. London ◽  
B. I. Levy ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vascular System ◽  
Diastolic Pressure ◽  
Arterial Compliance ◽  
Peripheral Resistance ◽  
Normal Subjects ◽  
K Value ◽  
Hypertensive Patients ◽  
Large Arteries ◽  
The Relationship

Cardiac output, blood pressure, and the characteristics of diastolic pressure decay were studied in 12 normal subjects and 23 sustained hypertensive patients of the same age. In normal subjects and in hypertensives, analysis of the diastolic decay showed that i) the form of the decay approximated a simple monoexponential curve during the last two-thirds of the diastolic segment, and ii) the time constant (t) of the curve was positively correlated with the total peripheral resistance (TPR), with an intercept of nearly zero. The validity of the relationship t = K x TPR was demonstrated both in groups of patients and also in individuals. Using a simple model for the vascular system, the K value was identified as the large arteries compliance and could thus be calculated in each individual. The values of arterial compliance was 1.26 +/- 0.04 ml.mmHg-1.m-2 in normal subjects and was significantly reduced in hypertensive patients (0.88 +/- 0.02 ml.mmHg=1.m-2,. P less than 0.001).

Maternal Prepregnancy Overweight and Offspring Fatness and Blood Pressure: Role of Physical Activity

2010 ◽  
Vol 22 (3) ◽  
pp. 369-378 ◽  
Author(s):  
Joey C. Eisenman ◽  
Mark A. Sarzynski ◽  
Jerod Tucker ◽  
Kate A. Heelan
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Vigorous Physical Activity ◽  
Self Report ◽  
Body Fatness ◽  
X Ray ◽  
Prepregnancy Bmi ◽  
Maternal Overweight ◽  
The Relationship

The purpose of this study was to examine if offspring physical activity may affect the relationship between maternal overweight and offspring fatness and blood pressure (BP). Subjects included 144 maternal-child pairs (n = 74 boys and 70 girls, mean age = 7.3 yrs). Maternal prepregnancy BMI was determined by self-report. Offspring characteristics included resting systolic and diastolic BP, body fatness by dual energy x-ray absorbtiometry, and moderate-to-vigorous physical activity (MVPA) using the Actigraph accelerometer. Children whose mothers were overweight or obese prepregnancy (Prepreg OW) were significantly larger and fatter than children from mothers with a normal prepregnancy BMI (Prepreg NORM). Prepreg OW children also had higher mean arterial pressure than Prepreg NORM children. BP values were not different across maternal Prepreg BMI/MVPA groups. Percent fat was significantly different across Prepreg BMI/MVPA groups. Prepreg OW children that did not meet the daily recommended value of MVPA were the fattest. Prepreg OW children that attained 360 min of MVPA/day had a mean percent body fat that was similar to Prepreg NORM children of either MVPA group.

Sport Participation and Metabolic Risk During Adolescent Years: A Structured Equation Model

2018 ◽  
Vol 39 (09) ◽  
pp. 674-681 ◽  
Author(s):  
André Oliveira Werneck ◽  
Danilo da Silva ◽  
Rômulo Fernandes ◽  
Enio Ricardo Vaz Ronque ◽  
Manuel Coelho-e-Silva ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Waist Circumference ◽  
Cardiorespiratory Fitness ◽  
Sport Participation ◽  
Equation Modeling ◽  
Metabolic Risk ◽  
Automatic Instrument ◽  
The Relationship ◽  
Blood Variables

AbstractSports practice during childhood can influence health indicators in later ages through direct and indirect pathways. Thus, this study aimed to test direct and indirect pathways to the association between sports practice in childhood and metabolic risk in adolescence, adopting physical activity, adiposity, and cardiorespiratory fitness at adolescence as potential mediators. This cross-sectional study with retrospective information was conducted with 991 adolescents (579 girls, 412 boys) aged 10 to 16 y. Sports activity was self-reported in childhood (retrospective data) and physical activity evaluated in adolescence through questionnaires. Somatic maturation (Mirwald method), cardiorespiratory fitness (20-m shuttle-run test), body fat (skinfolds), waist circumference, blood pressure (automatic instrument) and blood variables (fasting glucose, HDL cholesterol, and triglycerides) were measured at adolescence. Waist circumference, blood pressure and blood variables composed the metabolic risk score. Structured equation modeling was adopted. In both sexes, the relationship between sports practice at childhood and metabolic risk was fully mediated by habitual physical activity, which is related to the obesity construct and cardiorespiratory fitness. Obesity was associated with metabolic risk in boys (β=0.062; p<0.001) and girls (β=0.047; p<0.001). The relationship between sports practice in childhood and metabolic risk in adolescence was mediated by physical activity, obesity, and cardiorespiratory fitness.

Relationship of Age and Blood Pressure to Baroreflex Sensitivity and Arterial Compliance in Man

1976 ◽  
Vol 51 (s3) ◽  
pp. 357s-360s ◽  
Author(s):  
O. S. Randall ◽  
M. D. Esler ◽  
G. F. Bulloch ◽  
A. S. Maisel ◽  
C. N. Ellis ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Negative Correlation ◽  
Baroreflex Sensitivity ◽  
Arterial Compliance ◽  
Significant Negative Correlation ◽  
Arterial Distensibility ◽  
Blood Pressures ◽  
Relationship Of ◽  
The Relationship

1. The relationship between baroreflex sensitivity (BRS) and arterial compliance index (ACI) has been investigated (a) in paired subjects matched in one instance for systolic blood pressure with differing ages, and (b) in another instance matched for age with differing systolic blood pressures. 2. There was a significant negative correlation between BRS and age and between ACI and age in the twelve systolic blood pressure-matched subjects. 3. A significant negative correlation of systolic blood pressure with both BRS and ACI was observed in the fourteen age-matched subjects. 4. Both BRS and ACI appear to decrease with increasing age and systolic blood pressure. This decrease in BRS is probably due at least in part to the observed reduction in arterial distensibility.

Baroreflex modulation of sympathetic nerve activity to muscle in heat-stressed humans

2002 ◽  
Vol 282 (1) ◽  
pp. R252-R258 ◽  
Author(s):  
Jian Cui ◽  
Thad E. Wilson ◽  
Craig G. Crandall
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heat Stress ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Whole Body ◽  
Arterial Baroreflex ◽  
Nerve Activity ◽  
Arterial Blood ◽  
The Relationship

To identify whether whole body heating alters arterial baroreflex control of muscle sympathetic nerve activity (MSNA), MSNA and beat-by-beat arterial blood pressure were recorded in seven healthy subjects during acute hypotensive and hypertensive stimuli in both normothermic and heat stress conditions. Whole body heating significantly increased sublingual temperature ( P < 0.01), MSNA ( P < 0.01), heart rate ( P< 0.01), and skin blood flow ( P < 0.001), whereas mean arterial blood pressure did not change significantly ( P > 0.05). During both normothermic and heat stress conditions, MSNA increased and then decreased significantly when blood pressure was lowered and then raised via intravenous bolus infusions of sodium nitroprusside and phenylephrine HCl, respectively. The slope of the relationship between MSNA and diastolic blood pressure during heat stress (−128.3 ± 13.9 U · beats−1 · mmHg−1) was similar ( P = 0.31) with normothermia (−140.6 ± 21.1 U · beats−1 · mmHg−1). Moreover, no significant change in the slope of the relationship between heart rate and systolic blood pressure was observed. These data suggest that arterial baroreflex modulation of MSNA and heart rate are not altered by whole body heating, with the exception of an upward shift of these baroreflex curves to accommodate changes in these variables that occur with whole body heating.

The relationship between arterial compliance, age, blood pressure and serum lipid levels

1995 ◽  
Vol 13 (12) ◽  
pp. 1718???1723 ◽  
Author(s):  
James D. Cameron ◽  
Garry L. Jennings ◽  
Anthony M. Dart
Keyword(s):  
Blood Pressure ◽  
Serum Lipid ◽  
Arterial Compliance ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
The Relationship

Cardiorespiratory Fitness, Body Fatness, and Submaximal Systolic Blood Pressure Among Young Adult Women

2016 ◽  
Vol 25 (9) ◽  
pp. 897-903
Author(s):  
Vivek Kumar Prasad ◽  
Clemens Drenowatz ◽  
Gregory A. Hand ◽  
Carl J. Lavie ◽  
Xuemei Sui ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Young Adult ◽  
Systolic Blood Pressure ◽  
Cardiorespiratory Fitness ◽  
Adult Women ◽  
Young Adult Women ◽  
Body Fatness

Phenylephrine-induced elevations in arterial blood pressure are attenuated in heat-stressed humans

2002 ◽  
Vol 283 (5) ◽  
pp. R1221-R1226 ◽  
Author(s):  
Jian Cui ◽  
Thad E. Wilson ◽  
Craig G. Crandall
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heat Stress ◽  
Arterial Blood Pressure ◽  
Muscle Sympathetic Nerve Activity ◽  
Peripheral Resistance ◽  
Whole Body ◽  
Baroreflex Control ◽  
Arterial Blood ◽  
The Relationship

To test the hypothesis that phenylephrine-induced elevations in blood pressure are attenuated in heat-stressed humans, blood pressure was elevated via steady-state infusion of three doses of phenylephrine HCl in 10 healthy subjects in both normothermic and heat stress conditions. Whole body heating significantly increased sublingual temperature by ∼0.5°C, muscle sympathetic nerve activity (MSNA), heart rate, and cardiac output and decreased total peripheral vascular resistance (TPR; all P < 0.005) but did not change mean arterial blood pressure (MAP; P > 0.05). At the highest dose of phenylephrine, the increase in MAP and TPR from predrug baselines was significantly attenuated during the heat stress [ΔMAP 8.4 ± 1.2 mmHg; ΔTPR 0.96 ± 0.85 peripheral resistance units (PRU)] compared with normothermia (ΔMAP 15.4 ± 1.4 mmHg, ΔTPR 7.13 ± 1.18 PRU; all P < 0.001). The sensitivity of baroreflex control of MSNA and heart rate, expressed as the slope of the relationship between MSNA and diastolic blood pressure, as well as the slope of the relationship between heart rate and systolic blood pressure, respectively, was similar between thermal conditions (each P > 0.05). These data suggest that phenylephrine-induced elevations in MAP are attenuated in heat-stressed humans without affecting baroreflex control of MSNA or heart rate.

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