scholarly journals GND-PCA-Based Statistical Modeling of Diaphragm Motion Extracted from 4D MRI

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Windra Swastika ◽  
Yoshitada Masuda ◽  
Rui Xu ◽  
Shoji Kido ◽  
Yen-Wei Chen ◽  
...  

We analyzed a statistical model of diaphragm motion using regular principal component analysis (PCA) and generalized N-dimensional PCA (GND-PCA). First, we generate 4D MRI of respiratory motion from 2D MRI using an intersection profile method. We then extract semiautomatically the diaphragm boundary from the 4D-MRI to get subject-specific diaphragm motion. In order to build a general statistical model of diaphragm motion, we normalize the diaphragm motion in time and spatial domains and evaluate the diaphragm motion model of 10 healthy subjects by applying regular PCA and GND-PCA. We also validate the results using the leave-one-out method. The results show that the first three principal components of regular PCA contain more than 98% of the total variation of diaphragm motion. However, validation using leave-one-out method gives up to 5.0 mm mean of error for right diaphragm motion and 3.8 mm mean of error for left diaphragm motion. Model analysis using GND-PCA provides about 1 mm margin of error and is able to reconstruct the diaphragm model by fewer samples.

Dose-Response ◽  
2019 ◽  
Vol 17 (4) ◽  
pp. 155932581989235
Author(s):  
Gang Liu ◽  
Jing Yang ◽  
Xin Nie ◽  
Xiaohui Zhu ◽  
Xiaoqiang Li ◽  
...  

Purpose: To develop a patients-based statistical model of dose distribution among patients with nasopharyngeal cancer (NPC). Methods and Materials: The dose distributions of 75 patients with NPC were acquired and preprocessed to generate a dose-template library. Subsequently, the dominant modes of dose distribution were extracted using principal component analysis (PCA). Leave-one-out cross-validation (LOOCV) was performed for evaluation. Residual reconstruction errors between the doses reconstructed using different dominating eigenvectors and the planned dose distribution were calculated to investigate the convergence characteristics. Three-dimensional Gamma analysis was performed to investigate the accuracy of dose reconstruction. Results: The first 29 components contained 90% of the variance in dose distribution, and 45 components accounted for more than 95% of the variance on average. The residual error of the LOOCV model for the cumulative sum of components over all patients decreased from 8.16 to 4.79 Gy when 1 to 74 components were included in the LOOCV model. The 3-dimensional Gamma analysis results implied that the PCA model was capable of dose distribution reconstruction, and the accuracy was especially satisfactory in the high-dose area. Conclusions: A PCA-based model of dose distribution variations in patients with NPC was developed, and its accuracy was determined. This model could serve as a predictor of 3-dimensional dose distribution.


Proceedings ◽  
2018 ◽  
Vol 2 (10) ◽  
pp. 565
Author(s):  
Nguyen Nguyen Vu ◽  
Le Van Trung ◽  
Tran Thi Van

This article presents the methodology for developing a statistical model for monitoring salinity intrusion in the Mekong Delta based on the integration of satellite imagery and in-situ measurements. We used Landsat-8 Operational Land Imager and Thermal Infrared Sensor (Landsat- 8 OLI and TIRS) satellite data to establish the relationship between the planetary reflectance and the ground measured data in the dry season during 2014. The three spectral bands (blue, green, red) and the principal component band were used to obtain the most suitable models. The selected model showed a good correlation with the exponential function of the principal component band and the ground measured data (R2 > 0.8). Simulation of the salinity distribution along the river shows the intrusion of a 4 g/L salt boundary from the estuary to the inner field of more than 50 km. The developed model will be an active contribution, providing managers with adaptation and response solutions suitable for intrusion in the estuary as well as the inner field of the Mekong Delta.


Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 3730 ◽  
Author(s):  
Jhonatan Camacho ◽  
Andrés Quintero ◽  
Magda Ruiz ◽  
Rodolfo Villamizar ◽  
Luis Mujica

The implementation of damage-detection methods for continuously assessing structural integrity entails systems with attractive features such as storage capabilities, memory capacity, computational complexity and time-consuming processing. In this sense, embedded hardware platforms are a promising technology for developing integrated solutions in Structural Health Monitoring. In this paper, design, test, and specifications for a standalone inspection prototype are presented, which take advantage of piezo-diagnostics principle, statistical processing via Principal Component Analysis (PCA) and embedded systems. The equipment corresponds to a piezoelectric active system with the capability to detect defects in structures, by using a PCA-based algorithm embedded in the Odroid-U3 ARM Linux platform. The operation of the equipment consists of applying, at one side of the structure, wide guided waves by means of piezoelectric devices operated in actuation mode and to record the wave response in another side of the structure by using the same kind of piezoelectric devices operated in sensor mode. Based on the nominal response of the guide wave (no damages), represented by means of a PCA statistical model, the system can detect damages between the actuated/sensed points through squared prediction error (Q-statistical index). The system performance was evaluated in a pipe test bench where two kinds of damages were studied: first, a mass is added to the pipe surface, and then leaks are provoked to the pipe structure by means of a drill tool. The experiments were conducted on two lab structures: (i) a meter carbon-steel pipe section and (ii) a pipe loop structure. The wave response was recorded between the instrumented points for two conditions: (i) The pipe in nominal conditions, where several repetitions will be applied to build the nominal statistical model and (ii) when damage is caused to the pipe (mass adding or leak). Damage conditions were graphically recognized through the Q-statistic chart. Thus, the feasibility to implement an automated real-time diagnostic system is demonstrated with minimum processing resources and hardware flexibility.


2011 ◽  
Vol 38 (12) ◽  
pp. 6697-6709 ◽  
Author(s):  
David Staub ◽  
Alen Docef ◽  
Robert S. Brock ◽  
Constantin Vaman ◽  
Martin J. Murphy

Biomolecules ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 896
Author(s):  
Emili Besalú ◽  
Chantal Prat ◽  
Enriqueta Anticó

This study describes a new chemometric tool for the identification of relevant volatile compounds in cork by untargeted headspace solid phase microextraction and gas chromatography mass spectrometry (HS-SPME/GC-MS) analysis. The production process in cork industries commonly includes a washing procedure based on water and temperature cycles in order to reduce off-flavors and decrease the amount of trichloroanisole (TCA) in cork samples. The treatment has been demonstrated to be effective for the designed purpose, but chemical changes in the volatile fraction of the cork sample are produced, which need to be further investigated through the chemometric examination of data obtained from the headspace. Ordinary principal component analysis (PCA) based on the numerical description provided by the chromatographic area of several target compounds was inconclusive. This led us to consider a new tool, which is presented here for the first time for an application in the chromatographic field. The superposing significant interaction rules (SSIR) method is a variable selector which directly analyses the raw internal data coming from the spectrophotometer software and, combined with PCA and discriminant analysis, has been able to separate a group of 56 cork samples into two groups: treated and non-treated. This procedure revealed the presence of two compounds, furfural and 5-methylfurfural, which are increased in the case of treated samples. These compounds explain the sweet notes found in the sensory evaluation of the treated corks. The model that is obtained is robust; the overall sensitivity and specificity are 96% and 100%, respectively. Furthermore, a leave-one-out cross-validation calculation revealed that all of the samples can be correctly classified one at a time if three or more PCA descriptors are considered.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Jie Zhang ◽  
Wenna Guo ◽  
Qiao Li ◽  
Faxin Sun ◽  
Xiaomeng Xu ◽  
...  

Medicinal property, which is closely related to drug chemical profiling, is the essence of traditional Chinese medicine (TCM) theory and has always been the focus of modern Chinese medicine. Based on dozens of classic and commonly used TCM herbs with recognized medicinal properties, the present study just aimed to investigate the feasibility and reliability of medicinal property discriminant by using 1H-NMR spectrometry, which provided a mass of spectral data showing holistic chemical profile for multivariate analysis and data mining, including principal component analysis (PCA), Fisher linear discriminant analysis (FLDA), and canonical discriminant analysis (CDA). By using FLDA for two-class recognition, a large majority of test herbs (59/61) were properly discriminated as cold or hot group, and the only two exceptions were Chuanbeimu (Fritillariae Cirrhosae Bulbus) and Rougui (Cinnamomi Cortex), suggesting that medicinal properties interrelate with flavor and body tropism, and all these factors together bring up medicinal property and efficacy. While by performing CDA, 98.4% of the original grouped herbs and 77.0% of the leave-one-out cross-validated grouped cases were correctly classified. The findings demonstrated that discriminant analysis based on holistic chemical profiling data by 1H-NMR spectrometry may provide a powerful alternative to have a deeper understanding of TCM medicinal property.


Foods ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 38 ◽  
Author(s):  
Xiaohong Wu ◽  
Jin Zhu ◽  
Bin Wu ◽  
Chao Zhao ◽  
Jun Sun ◽  
...  

The detection of liquor quality is an important process in the liquor industry, and the quality of Chinese liquors is partly determined by the aromas of the liquors. The electronic nose (e-nose) refers to an artificial olfactory technology. The e-nose system can quickly detect different types of Chinese liquors according to their aromas. In this study, an e-nose system was designed to identify six types of Chinese liquors, and a novel feature extraction algorithm, called fuzzy discriminant principal component analysis (FDPCA), was developed for feature extraction from e-nose signals by combining discriminant principal component analysis (DPCA) and fuzzy set theory. In addition, principal component analysis (PCA), DPCA, K-nearest neighbor (KNN) classifier, leave-one-out (LOO) strategy and k-fold cross-validation (k = 5, 10, 20, 25) were employed in the e-nose system. The maximum classification accuracy of feature extraction for Chinese liquors was 98.378% using FDPCA, showing this algorithm to be extremely effective. The experimental results indicate that an e-nose system coupled with FDPCA is a feasible method for classifying Chinese liquors.


2005 ◽  
Vol 42 (6) ◽  
pp. 1031-1041 ◽  
Author(s):  
P. MANNING ◽  
P. D. PUTWAIN ◽  
N. R. WEBB

2012 ◽  
Vol 263-266 ◽  
pp. 416-420 ◽  
Author(s):  
Xiao Qing Luo ◽  
Xiao Jun Wu

Enhance spectral fusion quality is the one of most significant targets in the field of remote sensing image fusion. In this paper, a statistical model based fusion method is proposed, which is the improved method for fusing remote sensing images on the basis of the framework of Principal Component Analysis(PCA) and wavelet decomposition-based image fusion. PCA is applied to the source images. In order to retain the entropy information of data, we select the principal component axes based on entropy contribution(ECA). The first entropy component and panchromatic image(PAN) are performed a multiresolution decompositon using wavelet transform. The low frequency subband fused by weighted aggregation approach and high frequency subband fused by statistical model. High resolution multispectral image is then obtained by an inverse wavelet and ECA transform. The experimental results demonstrate that the proposed method can retain the spectral information and spatial information in the fusion of PAN and multi-spectral image(MS).


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