scholarly journals A Series of Unfortunate Events: Prinzmetal Angina Culminating in Transmural Infarction in the Setting of Acute Gastrointestinal Hemorrhage

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Michael Ruisi ◽  
Phillip Ruisi ◽  
Hugo Rosero ◽  
Paul Schweitzer

Prinzmetal angina or vasospastic angina is a clinical phenomenon that is often transient and self-resolving. Clinically it is associated with ST elevations on the electrocardiogram, and initially it may be difficult to differentiate from an acute myocardial infarction. The vasospasm induced in this setting occurs in normal or mildly to moderately diseased vessels and can be triggered by a number of etiologies including smoking, changes in autonomic activity, or drug ingestion. While the ischemia induced is usually transient, myocardial infarction and life-threatening arrhythmias can occur in 25% of cases. We present the case of a 65-year-old female where repetitive intermittent coronary vasospasm culminated in transmural infarction in the setting of gastrointestinal bleeding. This case highlights the mortality associated with prinzmetal angina and the importance of recognizing the underlying etiology.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lorenzo Storari ◽  
Valerio Barbari ◽  
Fabrizio Brindisino ◽  
Marco Testa ◽  
Maselli Filippo

Abstract Background Shoulder pain (SP) may originate from both musculoskeletal and visceral conditions. Physiotherapists (PT) may encounter patients with life-threatening pathologies that mimic musculoskeletal pain such as Acute Myocardial Infarction (AMI). A trained PT should be able to distinguish between signs and symptoms of musculoskeletal or visceral origin aimed at performing proper medical referral. Case presentation A 46-y-old male with acute SP lasting from a week was diagnosed with right painful musculoskeletal shoulder syndrome, in two successive examinations by the emergency department physicians. However, after having experienced a shift of the pain on the left side, the patient presented to a PT. The PT recognized the signs and symptoms of visceral pain and referred him to the general practitioner, which identified a cardiac disease. The final diagnosis was acute myocardial infarction. Conclusion This case report highlights the importance of a thorough patient screening examination, especially for patients treated in an outpatient setting, which allow distinguishing between signs and symptoms of musculoskeletal from visceral diseases.


BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e044117
Author(s):  
Wence Shi ◽  
Xiaoxue Fan ◽  
Jingang Yang ◽  
Lin Ni ◽  
Shuhong Su ◽  
...  

ObjectiveTo investigate the incidence of gastrointestinal bleeding (GIB) in patients with acute myocardial infarction (AMI), clarify the association between adverse clinical outcomes and GIB and identify risk factors for in-hospital GIB after AMI.DesignRetrospective cohort study.Setting108 hospitals across three levels in China.ParticipantsFrom 1 January 2013 to 31 August 2014, after excluding 2659 patients because of incorrect age and missing GIB data, 23 794 patients with AMI from 108 hospitals enrolled in the China Acute Myocardial Infarction Registry were divided into GIB-positive (n=282) and GIB-negative (n=23 512) groups and were compared.Primary and secondary outcome measuresMajor adverse cardiovascular and cerebrovascular events (MACCEs) are a composite of all-cause death, reinfarction and stroke. The association between GIB and endpoints was examined using multivariate logistic regression and Cox proportional hazards models. Independent risk factors associated with GIB were identified using multivariate logistic regression analysis.ResultsThe incidence of in-hospital GIB in patients with AMI was 1.19%. GIB was significantly associated with an increased risk of MACCEs both in-hospital (OR 2.314; p<0.001) and at 2-year follow-up (HR 1.407; p=0.0008). Glycoprotein IIb/IIIa (GPIIb/IIIa) receptor inhibitor, percutaneous coronary intervention (PCI) and thrombolysis were novel independent risk factors for GIB identified in the Chinese AMI population (p<0.05).ConclusionsGIB is associated with both in-hospital and follow-up MACCEs. Gastrointestinal prophylactic treatment should be administered to patients with AMI who receive primary PCI, thrombolytic therapy or GPIIb/IIIa receptor inhibitor.Trial registration numberNCT01874691.


Author(s):  
Eric Bonnefoy-Cudraz ◽  
Tom Quinn

The nature and complexity of acute cardiovascular care has changed markedly since the early days of the coronary care unit (CCU), introduced in the 1960s to prevent and treat life threatening arrhythmias associated with acute myocardial infarction. In the present day, the patient population is older, has more multimorbidity, comprises a range of conditions alongside critical cardiovascular disease and associated multi-organ failure, requiring increasingly sophisticated management. To reflect this, the Acute Cardiovascular Care Association (ACCA) published a comprehensive update of recommendations in 2018, developed by a multinational working group of experts. These recommendations, which inform this chapter, address the definition, structure, organisation and function of the contemporary intensive cardiovascular care unit (ICCU). Reflecting the modern casemix, three levels of acuity of care are described, and corresponding requirements for ICCU organisation defined. Recommendations on ICCU staffing (medical, nursing and allied professions), equipment and architecture, are presented, alongside considerations of the role of the ICCU within the wider hospital and cardiovascular care network.


Author(s):  
Pawan Gupta

Among surgical patients presenting to the ED, abdominal pain is the most common complaint, comprising 10% of ED visits. Evaluation of such patients in the ED is often challenging for a variety of reasons, such as the variability in the description of the perception of pain in individual patients, variable and changing physical findings with time, and life-threatening conditions presenting as seemingly benign symptoms. I always advise inexperienced doctors working in the ED to bear in mind seven time bombs that may be ‘sitting inside’ every adult patient’s abdomen who presents with abdominal pain. Patients who are discharged, but in whom one of these diagnoses was missed, will be blue-lighted back to the department dead. Therefore, before discharging a patient presenting with acute abdomen pain, all such conditions as listed below must be excluded beyond reasonable doubt. These conditions are: • Ruptured AAA • Hollow viscus perforation • Mesenteric ischaemia • Ruptured ectopic pregnancy • Acute pancreatitis • Intestinal obstruction • Acute myocardial infarction. Acute (inferior) myocardial infarction may present as upper abdominal pain and cannot afford to be missed. Patients >50 years presenting with abdominal pain must have an ECG in the ED, not only for detecting acute myocardial infarction, but for other associated cardiac problems precipitating an abdominal catastrophe. Elderly patients are more likely to have life-threatening conditions such as a ruptured AAA, mesenteric ischaemia, peptic perforation, and diverticulitis. Atypical presentations and rapid progression of these diseases, coupled with decreased diagnostic accuracy, may increase the risk of mortality in elderly patients. The only way to avoid the above is, as importantly as in other parts of medicine, by taking an accurate history, performing a thorough full clinical examination, arranging appropriate investigations rapidly, and making the correct decisions as to whether or not urgent surgery is required. Even with advanced imaging techniques, a good understanding of background clinical information is of utmost importance for accurate interpretation of imaging findings. This chapter includes questions on acute abdominal emergencies to give the reader an insight into the latest management strategies for these situations.


2016 ◽  
Vol 26 (8) ◽  
pp. 628-631 ◽  
Author(s):  
Dai Kawashima ◽  
Satoru Maeba ◽  
Masahiro Saito ◽  
Minoru Ono

Postinfarction ventricular septal rupture is a life-threatening complication of acute myocardial infarction. Although some novel techniques of ventricular septal rupture closure have been introduced, they involve ventriculotomy, a procedure that can cause a degree of impairment of the incised ventricle. We describe a case in which we closed a ventricular septal rupture through the tricuspid valve, without ventriculotomy.


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