scholarly journals Mean Platelet Volume Reflect Hematopoietic Potency and Correlated Blood Group O in Cord Blood from Healthy Newborn

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Hye Ryun Lee ◽  
Jeong Su Park ◽  
Sue Shin ◽  
Eun Youn Roh ◽  
Jong Hyun Yoon ◽  
...  
Keyword(s):  
Birth Weight ◽  
Cord Blood ◽  
Blood Group ◽  
Gestational Age ◽  
Mean Platelet Volume ◽  
Platelet Volume ◽  
Healthy Newborn ◽  
Cd34 Cells ◽  
The Relationship

We evaluated the relationship between mean platelet volume (MPV) and characteristics of 10,577 cord blood (CB) units in a public CB bank in Korea. Blood group O has the highest MPV (P= 0.002). MPV correlated with CB volume (r=0.121), Hb (r=0.377), WBC (r=0.111), TNCs (r=0.110), CD34+ cell (r=0.174), CD34+ cells/TNCs (r=0.157), gestational age (r= −0.102), and birth weight (r=0.023); (P<0.001in all). MPV may be one of the useful decision parameters of process priority in CB bank.

scholarly journals Variation of platelet parameters in preterm neonates

2021 ◽  
Vol 8 (5) ◽  
pp. 887
Author(s):  
Chandrakala P. ◽  
Krithika G. S.
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Mean Platelet Volume ◽  
Research Centre ◽  
Preterm Neonates ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
And Gender ◽  
Platelet Mass

Background: Platelets play a crucial role in hemostasis and phagocytosis. These functions of platelets are acquired gradually from foetal life to infant life. Larger, immature platelets are more reactive and hence platelet mass indices may be indicative of the thrombotic potential of platelets.Methods: This study was conducted in Kempegowda institute of medical sciences and research centre attached hospital in Bengaluru, Karnataka, India between January, 2019 and July, 2020. Platelet count, mean platelet volume (MPV), platelet distribution width (PDW) was obtained from automated analyzer reports (SYSMEX XT 1800i). The statistical association between the gestational age, birth weight and gender of preterm and their platelet parameters, was then assessed.Results: In this study, the effect of gestational age, birth weight and gender on platelet parameters was studied. A significant correlation between PDW (platelet distribution width), MPV (mean platelet volume) and gestational age was found. It was found that with increasing gestational age, both PDW and MPV decreased. With respect to birth weight, the mean, median PDW significantly decreased with increasing birth weight. None of the platelet parameters were different between male and female preterm neonates.Conclusions: There still remains a paucity of studies regarding the correlation between platelet mass indices and gestational age and birth weight. While some studies show positive correlation, some studies show no correlation and this study shows negative correlation. Hence, this calls for more studies, with larger sample sizes, to be undertaken.

Relationship between Leptin Concentration in Cord Blood and Foetal Growth and Maternal Anthropometry of GDM Mothers at Delivery

1970 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
S Jahan ◽  
TR Das ◽  
KB Biswas
Keyword(s):  
Body Mass Index ◽  
Birth Weight ◽  
Cord Blood ◽  
Body Mass ◽  
Anthropometric Measurements ◽  
Anthropometric Parameters ◽  
Serum Leptin ◽  
C Peptide ◽  
Cord Serum ◽  
The Relationship

Background and Aims: Cord blood leptin may reflect the leptinemic status of a newborn at birth more accurately than the leptin values of blood collected from other sites. The present study was undertaken to determine the relationship of cord serum leptin concentration at birth with neonatal and maternal anthropometric parameters. Materials and Methods: Blood was taken from the umbilical cord of the babies at delivery. Maternal anthropometric measurements were recorded at admission for delivery. Neonatal anthropometric measurements were recorded within 48 hours after delivery. Linear regression analysis was used to explore the relationship between cord serum leptin concentration and anthropometric parameters of the baby and the mother. Both Serum leptin and serum C-peptide levels were measured by chemiluminescence-based ELISA method. Results: The leptin concentration (ng/ml, mean±SD) in cord blood was 39.13±14.44. Cord leptin levels correlated with birth weight (r=0.673, p<0.0001), ponderal index (r=0.732, p<0.0001) but it did not correlate with maternal body mass index, gestational age (r=0.135, p=0.349) at delivery or cord serum C-peptide concentration (r=-0.049, p=0.735) or placental weight (r=0.203, p=0.157). Conclusion: There are associations between cord leptin concentration at delivery and birth weight, ponderal index (PI) of the babies but not body mass index (BMI) of the mothers. High leptin levels of the baby could represent an important feedback modulator of substrate supply and subsequently for adipose tissue status during late gestation. (J Bangladesh Coll Phys Surg 2007; 25 : 9-13)

scholarly journals Low birth weight, preterm birth and small for gestational age association with adult depression: systematic review and meta-analysis

2014 ◽  
Vol 205 (5) ◽  
pp. 340-347 ◽  
Author(s):  
Christian Loret De Mola ◽  
Giovanny Vinícius Araújo De França ◽  
Luciana de Avila Quevedo ◽  
Bernardo Lessa Horta
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Premature Birth ◽  
Fixed Effects ◽  
Meta Analysis ◽  
Adult Depression ◽  
Meta Analyses ◽  
Relationship Of ◽  
The Relationship

BackgroundThere is no consensus on the effects that low birth weight, premature birth and intrauterine growth have on later depression.AimsTo review systematically the evidence on the relationship of low birth weight, smallness for gestational age (SGA) and premature birth with adult depression.MethodWe searched the literature for original studies assessing the effect of low birth weight, premature birth and SGA on adult depression. Separate meta-analyses were carried out for each exposure using random and fixed effects models. We evaluated the contribution of methodological covariates to heterogeneity using meta-regression.ResultsWe identified 14 studies evaluating low birth weight, 9 premature birth and 4 SGA. Low birth weight increased the odds of depression (OR = 1.39, 95% CI 1.21–1.60). Premature birth and SGA were not associated with depression, but publication bias might have underestimated the effect of the former and only four studies evaluated SGA.ConclusionsLow birth weight was associated with depression. Future studies evaluating premature birth and SGA are needed.

scholarly journals Author response: The relationship between mean platelet volume and inflammation in varicocele pathophysiology

2015 ◽  
Vol 9 (9-10) ◽  
pp. 640 ◽  
Author(s):  
Coban Soner ◽  
Keles Ibrahim ◽  
Biyik Ismail ◽  
Guzeelsoy Muhammet ◽  
Turkoglu Ali Riza ◽  
...  
Keyword(s):  
Mean Platelet Volume ◽  
Author Response ◽  
Platelet Volume ◽  
The Relationship

THE RELATIONSHIP OF PLACENTAL THICKNESS WITHGESTATIONALAGE IN THIRD TRIMESTER AND PROBABLE FETAL OUTCOME

2021 ◽  
pp. 64-66
Author(s):  
Sambhunath Bandyopadhyay ◽  
Ritayan Sasmal ◽  
Debarshi Jana
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Age Determination ◽  
Fetal Outcome ◽  
Inclusion Criteria ◽  
Third Trimester ◽  
Relationship Of ◽  
The Relationship ◽  
Placental Thickness

Accurate gestational age determination is very important for management of continuation and termination planning of the pregnancy. rd To establish placental thickness as a parameter for determination of gestational age and fetal growth pattern at 3 trimester. 100 primigravida women who are fullling the inclusion criteria and attend gynae &obs OPD or admitted in their third trimester at IPGME&R from January 2017 to june 2018. Placental thickness at 3rd trimester USG scan is moderately correlated with gestational age, if placental thickness expressed in millimeter then it correlated with gestational age at weeks. rd st Placental thickness with >3.2 cm (32 mm) at 3 trimester almost associated with good fetal outcome, with APGAR score >8 at 1 min and birth weight >2500 gm.

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