Relationship between Leptin Concentration in Cord Blood and Foetal Growth and Maternal Anthropometry of GDM Mothers at Delivery

1970 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
S Jahan ◽  
TR Das ◽  
KB Biswas

Background and Aims: Cord blood leptin may reflect the leptinemic status of a newborn at birth more accurately than the leptin values of blood collected from other sites. The present study was undertaken to determine the relationship of cord serum leptin concentration at birth with neonatal and maternal anthropometric parameters. Materials and Methods: Blood was taken from the umbilical cord of the babies at delivery. Maternal anthropometric measurements were recorded at admission for delivery. Neonatal anthropometric measurements were recorded within 48 hours after delivery. Linear regression analysis was used to explore the relationship between cord serum leptin concentration and anthropometric parameters of the baby and the mother. Both Serum leptin and serum C-peptide levels were measured by chemiluminescence-based ELISA method. Results: The leptin concentration (ng/ml, mean±SD) in cord blood was 39.13±14.44. Cord leptin levels correlated with birth weight (r=0.673, p<0.0001), ponderal index (r=0.732, p<0.0001) but it did not correlate with maternal body mass index, gestational age (r=0.135, p=0.349) at delivery or cord serum C-peptide concentration (r=-0.049, p=0.735) or placental weight (r=0.203, p=0.157). Conclusion: There are associations between cord leptin concentration at delivery and birth weight, ponderal index (PI) of the babies but not body mass index (BMI) of the mothers. High leptin levels of the baby could represent an important feedback modulator of substrate supply and subsequently for adipose tissue status during late gestation. (J Bangladesh Coll Phys Surg 2007; 25 : 9-13)

2021 ◽  
Author(s):  
Renying Xu ◽  
Weixiu Zhao ◽  
Tao Tan ◽  
Haojie Li ◽  
Yanping Wan

Whether paternal epigenetic information of nutrition might be inherited by their offspring remained unknown. evaluate the relationship between preconception paternal body weight and their offspring's birth weight in 1,810 Chinese mother-father-baby trios. Information on paternal and maternal preconception body weight and height was collected via a self-reported questionnaire. Birth weight was collected from medical records. Paternal preconception body weight was associated with offspring's birth weight (p trend=0.02) after multivariable adjustment. Each standard deviation increment of paternal body mass index was associated with an additional 29.6 g increase of birth weight (95% confident interval: 5.7g, 53.5g). The association was more pronounced in male neonates, and neonates with overweight mothers, and with mothers who gained excessive gestational weight, compared to their counterparts (all p interaction<0.05). Sensitivity analyses showed similar pattern to that of the main analysis. Paternal preconception body weight was associated with birth weight of their offspring.


2020 ◽  
Vol 32 (3) ◽  
pp. 196
Author(s):  
Khalid Nasralla ◽  
Sumeya Khieri ◽  
Abdelilah Kunna ◽  
Zaheera Saadia ◽  
Ali Ali ◽  
...  

2020 ◽  
Vol 7 (4) ◽  
pp. 826
Author(s):  
Brinda Prasanna Kumar ◽  
E. Adarsh ◽  
Sahana G.

Background: Maternal pre-pregnancy BMI is well established to be a detrimental factor for prenatal development and neonatal anthropometric measures. Objectives of the study was to study the association between maternal pre-pregnancy Body Mass Index (BMI) and the anthropometry of the newborn.Methods: A hospital based cross-sectional, observational study was conducted that included 236 normal newborns and their mothers. A pre-designed questionnaire was used to collect relevant socio-demographic data and obstetric history. Details regarding maternal pre-pregnancy weight was collected from antenatal records at first antenatal visit, maternal height was measured and BMI was calculated. Neonatal anthropometric measurements including birth weight, recumbent length, head circumference, chest circumference and the mid arm circumference was measured.Results: In this study 49.6% of the women were in the age group of 21-25 years, 52.5% of them were multi-gravida and 56.4% had normal vaginal delivery. Among the newborns included in the study 25.8% had low birth weight. We saw a significant positive correlation between BMI and age, BMI and birth weight, BMI and chest circumference that is with increase in BMI there was significant increase in the age, birth weight and chest circumference and vice versa. There was no association between maternal BMI and mid-arm circumference or head circumference of the newborn.Conclusions: Study showed the association between maternal BMI and anthropometry of the newborn especially with respect to the BMI and birth weight, BMI and chest circumference. Thereby, establishing that interventions aimed at improving the nutritional status of the mother have a direct impact on the fetal growth outcomes.


Author(s):  
Zuhal Bulut ◽  
Deniz Gazel ◽  
Evrim Koç

Objective: Nugent scoring is accepted as the gold standard for diagnosis of bacterial vaginosis. Recently, it was reported that there could be a relationship between obesity and bacterial vaginosis. In this study, we aimed to investigate the relationship between bacterial vaginosis and obesity using Nugent score and body mass index (BMI). Method: A total of 106 fertile and sexually active patients in the childbearing age admitted to gynecology outpatient department of a state hospital in our city with symptoms of vaginal discharge and itching between May 1 and November 1, 2019 were included. Pregnant women, patients with bleeding, patients with a history of cancer, contraceptives/antibiotic/vaginal drug use within the previous three weeks, chronic disease and sexual intercourse within the last two days were excluded from the study. Anthropometric measurements and calculations of BMI were performed by the dietitian. Vaginal smears were obtained by a gynecologist and Nugent scoring was performed after Gram-staining. Results: According to Nugent score, patients were classified as having bacterial vaginosis, intermediate and normal flora. Using BMI, patients were classified as obese (36.8%), overweight (34.9%), and normal (28.3%). Nugent scoring method revealed that 33 (31.1%) of 106 patients had intermediate flora, 45 (42.5%) had bacterial vaginosis and 28 (26.4%) had normal flora. No significant relationship was found between BMI and bacterial vaginosis. Conclusion: We found no significant relationship between body mass index and bacterial vaginosis. Limited number of studies investigating the relationship between bacterial vaginosis and body mass index have contradictory results. Therefore, our study may help to close the gap on this issue.


2015 ◽  
Vol 2 (2) ◽  
pp. 90
Author(s):  
Andrés Rosa Guillamón ◽  
Eliseo García-Cantó ◽  
Juan José Pérez Soto ◽  
Pedro Luís Rodríguez García

Background and objective: The aim of this study was to analyze the relationship between aerobic capacity and other parameters determining fitness in primary school. Methods: A cross-sectional descriptive study, 298 schoolchildren (139 males and 159 females) aged 8-12. Body composition (weight and height) and physical fitness (capacity, motor aerobic and musculoskeletal) was assessed by ALPHA-Fitness battery. Aerobic capacity and body mass index (under/normal-weight and overweight/obesity) were categorized using standard criteria. The variable motor / muscle overall capacity was calculated, and the maximum oxygen consumption (VO2max) was indirectly estimated.  Results: The analysis of covariance (ANCOVA) found that men have better values in the test 4x10m (p <0.001), longitudinal jump (p <0.001), Course-Navette (p <0.001) and in VO2max (p <0.001). The ANOVA test showed that schoolchildren with better aerobic capacity have lower weight and body mass index (p <0.001 for both), better performance in the test longitudinal jump (p <0.001) and better overall motor / muscle capacity, and increased VO2max (p <0.001 for both). Conclusion: The results of this study suggest that schoolchildren with healthy cardiorespiratory fitness had better physical fitness and are more likely to have healthy anthropometric parameters.


2019 ◽  
Vol 7 (1) ◽  
pp. 13-16
Author(s):  
I G.A. Sri Dhyanaputri

Background Body mass index is the one of the marker of nutritional status related to obesity. Obesity is a multifactorial disease that can lead to an increase in triglycerides. This situation is one of the causes of cardiovascular disease. Objective This study aims to determine the relationship between body mass index in the levels of trigliycerides in weavers in Tenganan Village Karangasem. Methods Designed as study correlation study. The study was done to 26 respondents that were chosen by saturated sampling method. Data of body mass index were measured by anthropometric measurements and data of triglycerides level measured by using a dialab autolyser. The Results showed that 50,00% participants got obesity and 42,31% participants had increased triglycerides level, which six participants (23,08%) got a high limit and five participants (19,23%) in the high category. Based on the product moment test, a score is significant correlation between body mass index with triglycerides (p: 0,000) (α: 0,05). It was Concluded there is a relationship between body mass index with triglycerides level of weavers at Tenganan Village Karangasem.Keywords: body mass index, obesity, triglycerides


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