scholarly journals A Rare and Unusual Case of Burkitt’s Lymphoma Presenting with a Prostate Mass in a 12-Year-Old Boy

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
N. Sinclair ◽  
P. Babyn ◽  
M. Kinloch ◽  
R. Sinha

Burkitt’s lymphoma is the most frequent subtype of non-Hodgkin’s lymphoma in childhood. Radiographic findings are protean and can often overlap with other neoplastic and nonneoplastic processes. We present an unusual case of Burkitt’s lymphoma in a 12-year-old boy presenting with a one-week history of urinary retention, dysuria, and “tailbone pain,” as well as a 4-week history of jaw pain, initially treated as a dental abscess. On dental radiography, the patient was found to have resorption of alveolar bone adjacent to the lower first molars bilaterally, in keeping with “floating teeth,” classically associated with Langerhans cell histiocytosis. Additionally, a large, eccentric, prostatic mass was noted, prompting the inclusion of rhabdomyosarcoma on the differential diagnosis, with subsequent definitive diagnosis of Burkitt’s lymphoma on tissue and bone marrow biopsy. This case highlights the imaging overlap of these childhood neoplasms with an unusual lymphomatous prostate mass. It is important that the radiologists and pediatricians be aware of this potential overlap and the unusual presentation of Burkitt’s lymphoma.

2020 ◽  
Vol 13 (1) ◽  
pp. e233536
Author(s):  
Gerd Xuereb ◽  
Justine Borg ◽  
Kurt Apap ◽  
Charles Borg

Sporadic Burkitt’s lymphoma affecting the nasopharyngeal region is an extremely rare disease, especially in infants. We describe the case of a 2-year-old boy who presented to the ear, nose and throat department with a history of snoring, blood-stained rhinorrhoea and symptoms consistent with upper respiratory tract infections. Physical examination revealed massive cervical lymphadenopathy. MRI of the head and neck showed a mass lesion in the nasopharynx with bilateral lymph node enlargement. Debulking of the mass was performed and biopsies were sent for histology, which confirmed Burkitt’s lymphoma. The patient was treated with complex chemotherapy and had a good clinical response. The patient remains in remission after 6 years.


2017 ◽  
Vol 99 (7) ◽  
pp. e206-e208 ◽  
Author(s):  
R Simson ◽  
A Planner ◽  
Roderick Alexander

Colonic intussusception is rare in adults and can present with non-specific symptoms that can make diagnosis difficult and delayed. Unlike in children, it is commonly due to a pathological lead point that is often malignant. This case is the first reported case of adult intussusception due to Burkitt's lymphoma in the UK. We describe the case of a 22-year-old woman who presented with 4-week history of intermittent epigastric pain. On the third hospital admission, the diagnosis was made by abdominal computed tomography, which showed the ‘target’ sign, suggestive of intussusception. A right hemicolectomy was performed and histology later confirmed Burkitt’s lymphoma. This case demonstrates the difficulty in diagnosing intussusception in adults, which must be considered in recurrent abdominal pain when more common causes have been ruled out. The rare diagnosis of Burkitt’s lymphoma made early diagnosis and treatment important.


Oral Diseases ◽  
2008 ◽  
Vol 6 (4) ◽  
pp. 256-258 ◽  
Author(s):  
K. Mitsudo ◽  
I. Tohnai ◽  
Y. Hayashi ◽  
M. Ueda ◽  
M. Yambe ◽  
...  

Author(s):  
Masoume Jafar Aghaie ◽  
Mohsen Dehghani Zahedani

Burkitt lymphoma, as the most common non-Hodgkin Bcell lymphoma of childhood, is rarely detected in the gastrointestinal tract. Intussusception secondary to Burkitt’s lymphoma is an uncommon presentation. We describe an unusual case of intestinal Burkitt’s lymphoma in a four and the half-year-old girl who presented with intermittent colicky pain three times. Imaging studies were suggestive of intussusception. The patient was subjected to the surgery of bowel resection, which revealed a creamy-gray oval-shaped mass. Histopathology through immunohistochemistry study confirmed the Burkitt lymphoma. Owing to rather nonspecific clinical and radiological features, the preoperative diagnosis of Burkitt lymphoma remains a challenging task for pediatric surgeons and radiologists. Therefore, in case of any clinical suspicion, further examinations, such as CT scan in children are recommended.


2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii124-ii124
Author(s):  
Uju Momah ◽  
Jennifer Brewer ◽  
Anthony Tran ◽  
David Shapiro

Abstract Sporadic Burkitt’s Lymphoma accounts for only 1–2% of Non Hodgkin’s Lymphoma, and metastasizes to the central nervous system (CNS) is uncommon, occurring in about 13–17% of adult patients. 1 Melanoma is far more likely to metastasize to the CNS, occurring in about 37% of adult patients.2 Here we present the case of a 69 year old Gambian female with a prior medical history of plantar melanoma. She initially presented to her primary care provider with back pain and adenopathy, and was referred to surgical consultation for diagnosis and concern for recurrent melanoma. Her workup revealed metastatic Burkitt’s Lymphoma with disease in the abdomen, lungs and likely CNS involvement. This report chronicles her disease course and approach to management.


2015 ◽  
Vol 19 (5) ◽  
pp. 573 ◽  
Author(s):  
Rohit Jain ◽  
Neerja Sethi ◽  
Sangeeta Patankar ◽  
Ankit Mehta

2021 ◽  
Vol 12 ◽  
pp. 387
Author(s):  
Roberta Costanzo ◽  
Gianluca Scalia ◽  
Salvatore Marrone ◽  
Giuseppe Emmanuele Umana ◽  
Massimiliano Giuffrida ◽  
...  

Background: Burkitt’s lymphoma is a non-Hodgkin B-cell lymphoma, occurring mostly in Equatorial Africa. According to the WHO, classification is three different variants: sporadic, endemic, and immunodeficient-associated. Here, we present a patient with “sporadic” primary epidural Burkitt’s lymphoma resulting in chronic low back pain (LBP). Case Description: A 63-year-old female presented with a 2-month history of LBP and the left lower extremity sciatica. The thoracolumbar MRI showed a L5 irregular, osteolytic epidural lesion that was hypointense on T1-weighted images, hyperintense on STIR studies, and inhomogeneously enhanced with contrast. Additional hypointense lesions were also seen at the L2, L3, and L4 levels. The patient underwent a L4-L5 laminectomy for piecemeal epidural resection of tumor, and a L4-S1 transpedicular screws/rod fusion. In addition, a L2-L3 radiofrequency ablation was performed. The histological examination documented a primary “sporadic” spinal Burkitt’s lymphoma. The patient subsequently was treated with both radiotherapy/chemoradiotherapy Conclusion: Primary “sporadic” spinal Burkitt’s lymphoma is rare. Following tumor resection, adjunctive radiation and chemotherapy are typically warranted.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A1040-A1041
Author(s):  
Brian Khong ◽  
Maximiliano Hyon

Abstract Introduction: Langerhans Cell Histiocytosis (LCH) is a condition of malignant clonal proliferation of myeloid bone marrow cells that more commonly affects children than adults. Furthermore, its presentation remains variable ranging from single organ to multisystem involvement including bone, skin, lymph, liver, spleen, lung, and central nervous system. We report an unusual case of multisystem LCH in an adult female presenting with multiple soft tissue abscesses. Case: We report a case of a 38-year-old female with a past medical history of polysubstance abuse, type 2 diabetes, polycystic ovarian syndrome, and isolated central diabetes insipidus who had multiple hospitalizations for recurrent soft tissue abscesses treated with incision and drainage and antibiotics. Imaging studies revealed multiple osteolytic lesions involving the bilateral iliac crests, acetabulum and femur, as well as an iliopsoas abscess. Given her prior history of isolated central diabetes insipidus, the possibility of LCH as the cause was entertained. Histological evaluation performed on an inguinal soft tissue sample stained positive for CD1a and S100, and a formal diagnosis of Langerhans Cell Histiocytosis (LCH) was made. The patient was treated with chemotherapy with good results. Conclusion: This report presents a rare and unusual case of adult onset multisystem LCH involving bone, skin, lymph, and central nervous system presenting with recurrent large abdominopelvic abscesses. These abscesses may represent a rare and unrecognized form of soft tissue involvement of LCH.


2008 ◽  
Vol 9 (3) ◽  
pp. 142-148 ◽  
Author(s):  
Luiz Volpoto ◽  
Giberto Botelho ◽  
Luiz Casela ◽  
Álvaro Borges ◽  
Katia Silva

Abstract Aim This report presents an unusual case of regional odontodysplasia (RO) in the mandible which crosses the midline along with its clinical management. Background RO is an uncommon, nonhereditary unilateral developmental anomaly involving the dental hard tissues, most frequently affecting the maxillary teeth. Report RO was diagnosed in a 12-year-old. The dysplastic teeth were the mandibular canines, lateral incisors, central incisors, and the right premolars. The treatment was extraction of the affected teeth followed by provisory prosthetic rehabilitation. Summary The etiology of RO remains obscure. In this case a possible association with pre-natal trauma is suspected. The literature is not unanimous as to the management of RO. Nevertheless, the presence of a dental abscess is an indication for extraction. Since general bone quality is not affected, a provisory prosthesis was fabricated as the patient waits for future implant rehabilitation. The executed treatment met the expectations of the patient and her mother as it improved the patient's masticatory function, esthetics, and quality of life. Clinical Significance The general practitioner must be prepared to deal with different situations in the dental office. The diagnosis of RO relies mainly on clinical and radiographic findings, and its treatment depends on the affected teeth, the severity of the dysplasia, the presence of infection, and the patient's age. Citation Volpato L, Botelho G, Casela L, Borges Á, Silva K. Regional Odontodysplasia: Report of a Case in the Mandible Crossing the Midline. J Contemp Dent Pract 2008 March; (9)3:142-148.


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