scholarly journals Prenatal Detection of Congenital Heart Diseases: One-Year Survey Performing a Screening Protocol in a Single Reference Center in Brazil

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Luciane Alves Rocha ◽  
Edward Araujo Júnior ◽  
Liliam Cristine Rolo ◽  
Fernanda Silveira Bello Barros ◽  
Karina Peres da Silva ◽  
...  

Objective. To describe the experience of a tertiary center in Brazil to which patients are referred whose fetuses are at increased risk for congenital heart diseases (CHDs).Methods. This was a cross-sectional observational study. The data was collected prospectively, during the year 2012, through a screening protocol of the fetal heart adapted from the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) guideline. We performed a fetal echocardiogram screening for all pregnant women who were referred to the fetal cardiology outpatient obstetrics clinic of a university hospital. The exams were classified as normal or abnormal. The cases considered abnormal were undergone to a postnatal echocardiogram. We categorized the abnormal fetal heart according to severity in “complex,” “significant,” “minor,” and “others.”Results. We performed 271 fetal heart screening. The incidence of abnormal screenings was 9.96% (27 fetuses). The structural CHD when categorized due to severity showed 48.1% (n=13) of “complex” cases, 18.5% (n=5) “significant” cases, and 7.4% (n=2) “minor” cases. The most common referral reason was by maternal causes (67%) followed by fetal causes (33%). The main referral indication was maternal metabolic disease (30%), but there was just one fetus with CHD in such cases (1.2%). CHDs were found in 19/29 fetuses with suspicion of some cardiac abnormality by obstetrician (65.5%).Conclusion. We observed a high rate of CHD in our population. We also found that there was higher incidence of complex cases.

2019 ◽  
Vol 37 (1) ◽  
pp. 114-123
Author(s):  
Milene Carvalho Carrilho ◽  
Liliam Cristine Rolo ◽  
Gabriele Tonni ◽  
Edward Araujo Júnior

2018 ◽  
Vol 5 (3) ◽  
pp. 1023 ◽  
Author(s):  
Deveshwar Dev ◽  
Rambabu Sharma ◽  
Meenakshi Sharma

Background: Maternal tobacco consumption (both active and passive) during pregnancy as a risk factor for congenital heart diseases in off-springs has been studied by some workers with a small number of subjects hence requires to be evaluated through a study with a significant size of cohort. The objective of the study was to find out the association between maternal tobacco consumption and the risk of CHDs among their off springs.Methods: This is a hospital based, comparative, cross sectional, observational study. 518 children with CHDs, confirmed by echocardiography were included as cases and 240 children without any obvious congenital anomaly matched for age and sex were taken as controls. The following clinical observations were collected through questionnaires in a predesigned Performa: maternal and paternal tobacco consumption during pregnancy; maternal medical, gestational and obstetric history; and other birth defects.Results: Children from case and control groups were comparable with respect to age and sex at the inclusion in the study. Out of the total 758 study participants, 73 children (14.01%) with CHDs had history of maternal tobacco consumption (active consumption) during pregnancy and 86 children (16.6%) with CHDs had history of paternal smoking habit (P value was highly significant).Conclusions: Tobacco consumption during pregnancy (both active and passive) confer an increased risk of CHDs in their off springs (p value <0.001).


Author(s):  
Majid Firouzi ◽  
Hamidreza Sherkatolabbasieh ◽  
Alireza Nezami ◽  
Shiva Shafizadeh

Background: Congenital heart diseases are the most prevalent congenital abnormalities in the neonates, caused by the environmental and genetic factors and contribute to the leading cause of death. The aim of this study is to evaluate the relationship between neonates with large for gestational age and increased risk of congenital heart diseases among nondiabetic mothers. Methods: In this study, 179 neonates with large for gestational age in Khorramabad were enrolled where heart abnormalities were evaluated using echocardiography. Results: 87 neonates had more than 4000 g of the birth weight with no heart abnormalities and 92 (51%) macrosomic neonates had congenital heart diseases. Statistical analysis revealed that there was a significant relationship between birth weight and increased risk of acquiring congenital heart disease between the two groups. There was no significant relationship between birth weight, maternal age, gender, labor type and blood group between the two groups. The highest incidence of congenital heart anomalies was related to 38% of arterial septal defect (ASD) and 15.2% of ASD and VSD, respectively Conclusion: The most prevalent abnormality was arterial septal ASD. None of these abnormalities were associated with maternal age, birth weight and neonate gender. Future studies for congenital heart disease and neonatal birth weight are therefore, recommended.


2001 ◽  
Vol 82 (3) ◽  
pp. 161-164
Author(s):  
V. N. Medvedev ◽  
Sh. M. Kurmaev ◽  
G. I. Kharitonov ◽  
R. F. Sadekov ◽  
I. I. Vagizov

The results of treatment of 701 adult patients with congenital heart diseases from 1987 to 1997 are analyzed. As many as 248 operations with general postoperative lethality 3,2% are made. It is concluded on the necessity of improving the diagnosis of congenital heart diseases in children, especially in rural regions in relation to the high rate of inopportune revealing heart diseases resulting in the increase of the number of inoperable patients with pronounced pulmonary hypertension. The presence of symptoms or pronounced blood escape out of the left article into the right one in the absence of pulmonary hypertension is considered the indication to the radical correction of secondary defect of interatrial septum in adults. The radical heart disease correction in conditions of moderate hypotermy without artificial blood circulation is recommended in small secondary defect of interatrial septum


Author(s):  
Diesa Pinheiro ◽  
Bruna Varisco ◽  
Marcelo Silva ◽  
Rafaela Duarte ◽  
Graciele Deliberali ◽  
...  

Abstract Objective To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation. Methods A retrospective cohort study with 96 pregnant women who were attended at the Echocardiography Service and whose deliveries occurred at the Complexo Hospitalar Santa Casa de Porto Alegre, in the state of Rio Grande do Sul, Brazil. Risk factor assessment plus sensitivity and specificity analysis were used, comparing the accuracy of the screening for congenital heart disease by means of obstetrical ultrasound and morphological evaluation and fetal echocardiography, considering p < 0.05 as significant. The present study was approved by the Research Ethics Committee of the Institution. Results The analysis of risk factors shows that 31.3% of the fetuses with congenital heart disease could be identified by anamnesis. The antepartum echocardiography demonstrated a sensitivity of 97.7%, a specificity of 88.9%, and accuracy of 93% in the diagnosis of congenital heart disease. A sensitivity of 29.3% was found for the obstetric ultrasound, of 54.3% for the morphological ultrasound, and of 97.7% for the fetal echocardiography. The fetal echocardiography detected fetal heart disease in 67.7% of the cases, the morphological ultrasound in 16.7%, and the obstetric ultrasound in 11.5% of the cases. Conclusion There is a high proportion of congenital heart disease in pregnancies with no risk factors for this outcome. Faced with the disappointing results of obstetric ultrasound for the detection of congenital heart diseases and the current unfeasibility of universal screening of congenital heart diseases through fetal echocardiography, the importance of the fetal morphological ultrasound and its performance by qualified professionals is reinforced for a more appropriate management of these pregnancies.


2020 ◽  
Author(s):  
Kurt Taylor ◽  
Ahmed Elhakeem ◽  
Johanna Lucia Thorbjørnsrud Nader ◽  
Tiffany Yang ◽  
Elena Isaevska ◽  
...  

AbstractBackgroundCongenital heart diseases (CHDs) are the most common congenital anomaly. The causes of CHDs are largely unknown. Higher prenatal body mass index (BMI), smoking and alcohol consumption are associated with increased risk of CHDs. Whether these are causal is unclear.Methods and ResultsSeven European birth cohorts including 232,390 offspring (2,469 CHD cases [1.1%]) were included. We applied negative exposure paternal control analyses to explore the intrauterine effects of maternal BMI, smoking and alcohol consumption during pregnancy, on offspring CHDs and CHD severity. We used logistic regression and combined estimates using a fixed-effects meta-analysis. Analyses of BMI categories resulted in similar increased odds of CHD in overweight (mothers OR: 1.15 (1.01, 1.31) and fathers 1.10 (0.96, 1.27)) and obesity (mothers OR: 1.12 (0.93, 1.36) and fathers 1.16 (0.90, 1.50)). The association of mean BMI with CHD was null. Maternal smoking was associated with increased odds of CHD (OR: 1.11 (0.97, 1.25)) but paternal smoking was not (OR: 0.96 (0.85, 1.07)). The difference increased when removing offspring with genetic/chromosomal defects (mothers OR: 1.15 (1.01, 1.32) and fathers 0.93 (0.83, 1.05)). The positive association with maternal pregnancy smoking appeared to be driven by non-severe CHD cases (OR: 1.22 (1.04, 1.44)). Associations with maternal (OR: 1.16 (0.52, 2.58)) and paternal (OR: 1.23 (0.74, 2.06)) moderate/heavy pregnancy alcohol consumption were similar.ConclusionsWe found evidence of an intrauterine effect for maternal smoking on offspring CHDs, but no evidence for higher maternal BMI or alcohol consumption. Our findings provide further support for why smoking cessation is important during pregnancy.


2017 ◽  
Vol 4 (3) ◽  
pp. 1021
Author(s):  
Doddabasava K ◽  
Prijo Philip ◽  
Sumanth Shetty B ◽  
Chinthu Sara Jacob ◽  
Subramanyam K

Background: Echocardiography has supplanted clinical acumen in diagnosis of congenital heart diseases (CHDs). Prevalence rates of CHDs across various regions of the world are subject to change over the course of time, with increasing use of this diagnostic modality. Objective: To assess the prevalence and types of CHDs.Methods: The study was conducted at a tertiary care center in South Karnataka, India. Transthoracic echocardiographic records of all patients suspected to have congenital heart disease, over a period of 60 months were analyzed. Categorization of data into acyanotic and cyanotic congenital heart disease, and further, into different types was done after an exhaustive search. Specific variables such as age, frequency and gender distribution of all kinds of CHDs were computed.Results: Of a total 112,372 pediatric patients who attended our center, 1451 reports of subjects suspected to have CHDs were analyzed. The prevalence was found to be 6.22 per 1000 subjects. Of the 700 subjects (48.24%) with CHD, 664 (94.85%) were diagnosed to have Acyanotic Congenital Heart Disease and 36 (5.14%) were diagnosed to have Cyanotic Congenital Heart Disease. Among the Acyanotic CHD, Atrial Septal Defect (ASD) was found to be the most common (40.21%) seconded by Ventricular Septal Defect (VSD) (21.53%). Among the 36 subjects diagnosed to have Cyanotic CHD, it was found that Tetralogy of Fallot (TOF) was the most commonest lesion (61.11%).Conclusions: Increased utilization of Echocardiography as a diagnostic modality significantly helps to better appreciate ever varying prevalence rates and types of CHDs in different parts of India. Frequent longitudinal studies in this regard help in enhanced allocation of available resources and updating of available databases. 


2007 ◽  
Vol 5 (3) ◽  
pp. 0-0
Author(s):  
Virgilijus Lebetkevičius ◽  
Virgilijus Tarutis ◽  
Rita Sudikienė ◽  
Daina Liekienė ◽  
Kęstutis Lankutis ◽  
...  

Virgilijus Lebetkevičius1, Virgilijus Tarutis1, Rita Sudikienė1, Daina Liekienė1, Kęstutis Lankutis1, Giedrė Nogienė1, Vidmantas Jonas Žilinskas1, Vytautas Sirvydis1, Kęstutis Versockas2, Žydrė Jurgelienė2, Asta Bliūdžiūtė21 Vilniaus universiteto Širdies chirurgijos centras, Santariškių g. 2, LT-08661 Vilnius2 Vilniaus universiteto ligoninės Santariškių klinikų Anesteziologijos,intensyviosios terapijos ir skausmo gydymo centras, Santariškių g. 2, LT-08661 VilniusEl paštas: [email protected] Tikslas Apžvelgti Vilniaus universiteto Širdies chirurgijos centro naujagimių įgimtų širdies ydų chirurgijos rezultatus, juos įvertinti ir padaryti išvadas. Metodai Nuo 1964 iki 2006 metų Vilniaus universiteto Širdies chirurgijos centre atlikta 5066 įgimtų širdies ydų operacijos vaikams iki 18 metų. Naujagimių dalis – 307 operacijos (6,1%). Korekcijos naujagimiams atliktos naudojant dirbtinę kraujo apytaką (DKA) ir be jos. Rezultatai Įgimtų širdies ydų operacijos suskirstytos į keturis etapus. 1974–1990 metai (1974 m. atlikta pirmoji širdies operacija naujagimiui). Tuo laikotarpiu mirštamumas buvo 100%. 1991–1995 metais – mirštamumas 71%, 1996–2000 metais – mirštamumas 68%, 2001–2006 metais – mirštamumas 38%, 2006 metais mirštamumas – 22%. Išvados Analizuojant naujagimių širdies chirurgijos rezultatus, pažymėtina, kad per pastaruosius metus mirštamumas sumažėjo iki priimtinų dydžių, kurie artėja prie kitų pasaulio širdies chirurgijos klinikų rezultatų. Gerėjant visam kompleksui tyrimo, gydymo, slaugymo priemonių visose grandyse (kardiologija, anesteziologija-reanimatologija, chirurgija), mirštamumą įmanoma sumažinti iki minimalaus. Pagrindiniai žodžiai: įgimtos širdies ydos, širdies chirurgija, naujagimiai Corrective surgery of congenital heart defects: experience of Vilnius University Heart Surgery Centre Virgilijus Lebetkevičius1, Virgilijus Tarutis1, Rita Sudikienė1, Daina Liekienė1, Kęstutis Lankutis1, Giedrė Nogienė1, Vidmantas Jonas Žilinskas1, Vytautas Sirvydis1, Kęstutis Versockas2, Žydrė Jurgelienė2, Asta Bliūdžiūtė21 Vilnius University, Heart Surgery Centre, Santariškių str. 2, LT-08661 Vilnius2 Vilnius University Hospital „Santariškių klinikos“, Anaesthesiology Intensive Careand Pain Management Centre, Santariškių str. 2, LT-08661 VilniusE-mail: [email protected] Objective To access the outcome and mortality trend in newborns undergoing corrective surgery for congenital heart defect. Methods We reviewed the hospital records on 307 neonates under 30 days of life, who had congenital heart defects operated on at the Heart Surgery Center of Vilnius University, Lithuania, in 1994 through 2006. Early and late mortality results were analyzed. Results From January 1974 to 2006, 307 neonates with congenital heart disease underwent surgical repair at Heart Surgery Clinic of Vilnius University. It came to 6.1% of all 5066 procedures of the congenital heart diseases performed. The number of neonate operations considerably increased in the later years, because a special department with proper technique was established. 144 neonates underwent surgery repair with cardiopulmonary bypass and 163 neonates were operated on without cardiopulmonary bypass. The mean age of the patients was 11.8 ± 0.28 days. There were 113 girls and 194 boys. Conclusions Mortality from 71% in 1991–1995 dropped to 38% in 2001–2006 and 22% in 2006. Key words: congenital heart diseases, cardiosurgery, neonates


2020 ◽  
Vol 17 (4) ◽  
pp. 285-291
Author(s):  
Pelin Koşger ◽  
Melih Velipaşaoğlu ◽  
Tuğçem Keskin ◽  
Hikmet Kıztanır ◽  
Birsen Uçar

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