scholarly journals Prevalence and Risk Factors for Oral Potentially Malignant Disorders in Indian Population

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Sandeep Kumar ◽  
Nitai Debnath ◽  
Mohammed B. Ismail ◽  
Arunoday Kumar ◽  
Amit Kumar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Indian Population ◽  
Dietary Habits ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Areca Nut ◽  
Oral Potentially Malignant Disorders ◽  
Cross Sectional ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant

Objective. To assess the prevalence of oral potentially malignant disorders and to determine the potential risk factors for its development in Indian population.Materials and Methods. This cross-sectional study was carried out on 1241 individuals in Indore, Madhya Pradesh. A questionnaire was designed to record information about sociodemographic characteristics, oral hygiene practices, dietary habits, and risk factors for oral potentially malignant disorders. Oral mucosal lesions were examined by a skilled person.Results. The overall prevalence of oral potentially malignant disorders was found to be 13.7% with oral submucous fibrosis (8.06%) found to be more common and erythroplakia (0.24%) found to be least prevalent. Results of Logistic Regression analysis showed that males (OR = 2.09,Pvalue < 0.0001) who were ever consumers of tobacco (OR = 2.06,Pvalue = 0.030) and areca nut chewing (OR = 2.64,Pvalue = 0.004) were more likely to develop oral potentially malignant disorders compared to never consumers. Diabetic (OR = 2.21,Pvalue = 0.014) and underweight individuals (OR = 2.23,Pvalue = 0.007) were more likely to suffer from oral potentially malignant disorders.Conclusion. The study reinforces the association of tobacco and areca nut consumption with oral potentially malignant disorders. An association of oral potentially malignant disorders with diabetes and BMI was confirmed by this study.

scholarly journals EXFOLIATIVE CYTOLOGICAL FINDINGS IN ORAL POTENTIALLY MALIGNANT DISORDERSMALIGNANT DISORDERS

2021 ◽  
Vol 29 (01) ◽  
pp. 2-5
Author(s):  
Mehwish Waris ◽  
Sajjad Ahmad ◽  
Muhammad Mumtaz Khan ◽  
Sabeen Nasir ◽  
Qurat-ul-ain Mushtaq ◽  
...  
Keyword(s):  
Tobacco Use ◽  
Cross Sectional Study ◽  
Healthy Controls ◽  
Oral Potentially Malignant Disorders ◽  
Cross Sectional ◽  
Female Ratio ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant ◽  
History Of ◽  
Cytological Changes

Objective: Patients with oral potentially malignant disorders (OPMDs) are at risk for development of malignancy and tobacco use contributes in its transformation. This study was designed to assess exfoliative cytological findings in OPMD cases using tobacco and healthy controls with no history of tobacco use. The aim was to screen OPMD cases for biopsy with the help of brush cytology. Materials and Methods: This comparative cross-sectional study was conducted at Histopathology Laboratory of Peshawar Medical College, Peshawar for which samples were collected from two dental hospitals and private dental clinics of Peshawar. The study included 20 cases of clinically diagnosed Oral Potentially Malignant Disorders (OPMDs) with history of tobacco use; including 10 cases of leukoplakia and 10 cases of oral lichen planus (OLP), and 20 age and gender matched healthy controls with no history of tobacco use, after observing a strict inclusion and exclusion criteria. A pre-designed proforma was used to collect the data, which was later analyzed in SPSS version 21. Results:  A total of 40 participants had a mean age of 48.25±10.01 years with gender distribution of 32(80%) males and 8(20%) females, giving a male to female ratio of 4:1. The duration of tobacco use in cases had a mean of 22.95 ± 9.17 years, while duration of lesion had a mean of 2.3±4.4 years. As per Oral Bethesda Criteria, 18 (90%) OPMD cases were Negative for Intraepithelial Lesion/Malignancy (NILM). Buccal mucosa 12(60%) was the most common site of lesions. On Oral Exfoliative Cytology (OEC), OPMDs showed mild to moderate cytological changes as compared to healthy controls. Conclusion: This study concluded that most of the OPMD cases show mild to moderate cytological changes as compared to healthy controls. Dysplastic changes were seen only in 10% of OPMD cases that needed further assessment through biopsy. 

scholarly journals A Study to Analyze Different Patterns of Quid Usage among Subjects with Oral Submucous Fibrosis in Mangalore Population

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Vidya A. Holla ◽  
L. K. Chatra ◽  
Prashanth Shenai ◽  
Devika Shetty ◽  
Ashwini Baliga
Keyword(s):  
Clinical Stage ◽  
Oral Submucous Fibrosis ◽  
Cross Sectional Study ◽  
Areca Nut ◽  
Age Group ◽  
Cross Sectional ◽  
Potentially Malignant ◽  
Carcinogenic Effects ◽  
Submucous Fibrosis ◽  
Youth Population

Aim and Objectives. Oral submucous fibrosis (OSF) is a potentially malignant disorder associated with the usage of areca nut. Usage of processed forms of areca nut is popular among the youth and its carcinogenic effects are not well known. Due to large immigrant population, various patterns of areca nut usage are seen. The aim of this study is to assess the various quid chewing patterns and their association with severity of OSF.Materials and Methods. A cross-sectional study was carried out with 250 cases clinically and histologically diagnosed as having OSF lesion that were selected and subjected to a detailed habit history which was recorded through preformed questionnaire. The data obtained was statistically analyzed.Results. Among the 250 subjects, males were seen to be affected more than females within the age group of 26–35 years and were having clinical stage I OSF. A combination of processed areca nut and processed tobacco was used by the majority of the subjects with duration of 1 to 5 years, at a frequency of 3 to 5 quids per day.Conclusion. The present study confirms the association between oral submucous fibrosis and the quid containing processed areca nut and processed tobacco and also highlights the increasing youth population using the processed forms of areca nut.

scholarly journals Prevalence and risk factors for oral potentially malignant disorders in Indian population

2021 ◽  
Vol 13 (5) ◽  
pp. 398
Author(s):  
AmitKumar Singh ◽  
Rashi Chauhan ◽  
Kumar Anand ◽  
Manisha Singh ◽  
SomeshRanjan Das ◽  
...  
Keyword(s):  
Risk Factors ◽  
Indian Population ◽  
Oral Potentially Malignant Disorders ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant

scholarly journals Prevalence of Gul Use, Its Predictors and Association With Oral Potentially Malignant Disorders and Oral Cancer Development in the Users of Noida, India: A Cross-Sectional Study

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 24s-24s
Author(s):  
S.T. Nethan ◽  
V. Kumar ◽  
S. Sharma ◽  
R. Hariprasad ◽  
R. Mehrotra
Keyword(s):  
Oral Cancer ◽  
Tobacco Use ◽  
Dental Pain ◽  
Cross Sectional Study ◽  
Cancer Development ◽  
Sectional Study ◽  
Oral Potentially Malignant Disorders ◽  
Cross Sectional ◽  
Potentially Malignant Disorders ◽  
Potentially Malignant

Background: Oral cancer is the third most common cancer in India which is attributed to the high tobacco burden especially due to a myriad of smokeless tobacco (SLT) products available in the market. Gul/Gul manjan is a commercially-produced, tobacco-based dentifrice, indigenous to rural India and Bangladesh, and mainly used by women. It is both highly addictive and carcinogenic; yet its prevalence, reasons for use and association with oral potentially malignant disorders (OPMDs) and oral cancer are scarcely documented in literature, making this study the first of its kind. Aim: To determine the prevalence of Gul use, its predictors and resultant OPMDs and oral cancer in such consumers. Methods: A cross-sectional study was performed among 3452 individuals visiting the Institute's Oral Health Promotion Clinic between December 2016-March 2018. Their basic demographic details, tobacco use history and abnormalities found on oral examination, were documented in the clinical record form. Data pertaining to Gul users was subjected to further statistical analysis. Results: Of the total individuals screened, 2.9% (n=101, P < 0.001) consumed Gul (89.1% current and 10.9% former users), with majority female consumers (86.1%) from peri-urban Noida. It was used (up to 5 times daily) mainly to alleviate dental pain due to caries/endodontic lesions, which were present in 35.6% users ( P = 0.004). A statistically significant positive association was seen between Gul use and development of OPMDs ( P < 0.001) and oral cancer ( P = 0.001), with 7.9% (n=10; 70% Gul alone users) of the overall leukoplakias/preleukoplakias (n=127), and 7.1% (n=1, Gul alone user) of all the oral cancer cases (n=14), found in Gul users. The duration of Gul use ranged up to 25 years, indicating its high dependency. Conclusion: Gul use is relatively uncommon than other SLT products in India, even among males (the major group of tobacco consumers). Apart from teeth cleaning, Gul is a cheap, easily accessible antidote for acute dental pain relief (owing to nicotine-induced analgesia) among rural women who apply it multiple times daily onto the affected teeth and adjacent gum/mucosa, often leading to its dependency. Courtesy its significant carcinogenic potential which has been clearly reported here (OPMDs and oral cancer development among users), combating/preventing its production, easy availability (in spite of the complete ban on tobacco use in dentifrices) and consumption, is essential. Therefore, the public health challenge of prevention of the use of this form of SLT ie tobacco-based dentifrices, warrants greater interest and action than that has been received thus far, which in turn would contribute to the overall mission of oral cancer prevention.

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