scholarly journals Prevalence and risk factors for oral potentially malignant disorders in Indian population

2021 ◽  
Vol 13 (5) ◽  
pp. 398
Author(s):  
AmitKumar Singh ◽  
Rashi Chauhan ◽  
Kumar Anand ◽  
Manisha Singh ◽  
SomeshRanjan Das ◽  
...  
2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Sandeep Kumar ◽  
Nitai Debnath ◽  
Mohammed B. Ismail ◽  
Arunoday Kumar ◽  
Amit Kumar ◽  
...  

Objective. To assess the prevalence of oral potentially malignant disorders and to determine the potential risk factors for its development in Indian population.Materials and Methods. This cross-sectional study was carried out on 1241 individuals in Indore, Madhya Pradesh. A questionnaire was designed to record information about sociodemographic characteristics, oral hygiene practices, dietary habits, and risk factors for oral potentially malignant disorders. Oral mucosal lesions were examined by a skilled person.Results. The overall prevalence of oral potentially malignant disorders was found to be 13.7% with oral submucous fibrosis (8.06%) found to be more common and erythroplakia (0.24%) found to be least prevalent. Results of Logistic Regression analysis showed that males (OR = 2.09,Pvalue < 0.0001) who were ever consumers of tobacco (OR = 2.06,Pvalue = 0.030) and areca nut chewing (OR = 2.64,Pvalue = 0.004) were more likely to develop oral potentially malignant disorders compared to never consumers. Diabetic (OR = 2.21,Pvalue = 0.014) and underweight individuals (OR = 2.23,Pvalue = 0.007) were more likely to suffer from oral potentially malignant disorders.Conclusion. The study reinforces the association of tobacco and areca nut consumption with oral potentially malignant disorders. An association of oral potentially malignant disorders with diabetes and BMI was confirmed by this study.


Author(s):  
MAURÍLIA RAQUEL DE SOUTO MEDEIROS ◽  
HALINE CUNHA DE MEDEIROS MAIA ◽  
NAJARA ALCÂNTARA SAMPAIO PINTO ◽  
JOABE DOS SANTOS PEREIRA ◽  
ANA MIRYAM COSTA DE MEDEIROS ◽  
...  

Author(s):  
Prangtip Worakhajit ◽  
Pornpoj Fuangtharnthip ◽  
Siribang-on Piboonniyom Khovidhunkit ◽  
Pim Chiewwit ◽  
Boworn Klongnoi

This study’s objective was to describe the relationship between the main risk factors for oral cancer, including tobacco (in the form of cigarettes, smokeless tobacco (SLT), secondhand smoking (SS)), alcohol, and betel quid (BQ), and the occurrence of oral potentially malignant disorders (OPMDs). A community-based case-control study was conducted with a population of 1448 adults aged 40 years or above in northeastern Thailand. Patients aged 60 years or above (OR 1.79, p < 0.001) and female patients (OR 2.17, p < 0.001) had a significant chance of having OPMDs. Our multivariate analysis showed that the most potent risk factor for OPMDs occurrence was betel quid (BQ) (adjusted OR 4.65, p < 0.001), followed by alcohol (OR 3.40, p < 0.001). Even former users were at risk of developing OPMDs. The synergistic effect between these main risk factors was significantly shown in the group exposed to SLT, SS, BQ, and alcohol. The most potent synergistic effect was found in the group exposed to SLT, BQ and alcohol with the OR = 20.96.


Author(s):  
Jyoti Raghavendra Byakodi ◽  
Pushpanjali Krishnappa

Introduction: The increase in prevalence of oral premalignant lesions and oral cancer in India is due to cultural, ethnic, geographic factors and varying lifestyle factors like consumption of tobacco, alcohol and standard of living. Some of the risk factors are modifiable and emphasises the need for detailed assessment of these modifiable risk factors and increasing awareness among general public and policy makers. Aim: The present study was conducted to assess the association between lifestyle factors and Oral Potentially Malignant Disorders (OPMDs). Materials and Methods: A case-control study was conducted where 154 cases and controls were selected from MS Ramaiah Dental College and Hospital, Bangalore and peripheral outreach centers of MS Ramaiah Dental College and Hospital, Bangalore. Cases diagnosed as oral leukoplakia, erythroplakia and Oral Submucous Fibrosis (OSMF) based on the World Health Organisation (WHO) criteria (1980) were included in the study group. Age and sex (1:1) matched controls without OPMDs were included in control group. The data was collected regarding socio-demographic factors, blood group and lifestyle factors using specially designed proforma. Chi-square test and odds ratio were utilised to association and strength of association between various lifestyle factors and development of OPMDs. Univariate logistic regression test was done followed by multiple logistic regression for identifying the risk factors. The p-value <0.05 was considered as statistically significant. SPSS version 11.0 was used for data analysis. Results: Out of 154 cases, 84 (54.5%) cases were leukoplakia, 2 (1.3%), cases were erythroplakia, 53 (34.4%) cases were OSMF and 15 (9.7%) cases were with multiple potentially malignant disorders (leukoplakia+OSMF). In univariate analysis, OR for tobacco smoking in individuals who smoked more than 20 times a day was 2.56 (95% CL 1.19-5.5) compared to non-smokers, tobacco chewing who chewed more than 10 times a day was 43.03 (95% CL-17.2-107) in comparison to non-chewers and alcohol consumption who consumed alcohol daily was 3.2 (95% CL 0.6-16.3) in comparison to non-alcoholics. Following multiple logistic regression analysis occupation, smoking, chewing tobacco and vegetable intake was found to be statistically significant as independent risk factors p<0.05. Conclusion: Occupation, smoking, chewing tobacco and vegetable consumption were identified as independent risk factors for the development of OPMDs. Identifying the risk factors and OPMD at an early stage is important for prevention of oral cancer.


2019 ◽  
Vol 92 (1) ◽  
pp. 66-71
Author(s):  
Swati Balsaraf ◽  
Ajay Bhambal ◽  
Revant Chole

Background and aims. Oral potentially malignant disorders constitute one of the major oral health problems in India. Few studies have been undertaken on potentially malignant disorders in central India, specifically in Bhopal. Hence the present study was conducted to assess the oral potentially malignant disorders in the patients attending hospitals of Bhopal, India.Methods. Four hundred subjects diagnosed with oral potentially malignant disorders were included in this study. Detailed information was gathered in a proforma and emphasis was given to the various addictions and clinical findings.Results. Among the 400 oral potentially malignant disorders diagnosed during the study period, males constituted 78% (n=312) and females 22% (n=88). The mean age of the patients was 33.50 ± 13.24 years for males and 42.60 ± 14.18 years for females. The most commonly affected age group was 21-30 years (37.5%), followed by 31-40 years (25%) and 41-50 years (13%). 87.75% patients were addicted to chewing of betel nut and/or tobacco and/or betel quid, 15.25% were addicted to smoking bidi and/or cigarette, 15.25% were addicted to chewing and smoking, 1% was addicted to chewing and alcohol, and 0.25% was addicted to alcohol and smoking.Conclusion. In this study, an increase in clinical grading of oral potentially malignant disorders was found with severity and duration of addiction habit. In order to decrease the prevalence of these disorders, it is imperative to continue educational campaigns at national and international level to impart education to the public about the risk factors and early signs and symptoms of the oral potentially malignant disorders.


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