scholarly journals Isolated Subclinical Hyperthyrotropinemia in Obese Children: Does Levothyroxine (LT4) Improve Weight Reduction during Combined Behavioral Therapy?

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Pawel Matusik ◽  
Aneta Gawlik ◽  
Aleksandra Januszek-Trzciakowska ◽  
Ewa Malecka-Tendera

Objective. The study aim was to analyze whether anthropometrical parameters and TSH values in obese children with isolated subclinical hypothyroidism (IsHT) treated with levothyroxine (LT4) and weight reduction program differ from those managed by dietary and behavior counselling only.Material and Methods. 51 obese children with IsHT, who were treated according to the same weight reduction program, were retrospectively analyzed. They were divided into two groups: Group 1,n=26, and Group 2,n=25, without or with LT4 therapy, respectively. Changes in anthropometrical (delta BMIz-score) and hormonal (delta TSH) status were analyzed at the first follow-up visit.Results. In both groups significant decrease of TSH and BMIz-score values were noted. TSH normalized in 80.9% of children from Group 1 versus 90.5% from Group 2,p= NS. Delta BMIz-score was insignificantly higher in Group 1 compared to Group 2. Delta TSH was significantly related to initial TSH level in children treated by lifestyle intervention program only.Conclusions. In obese children with sHT dietary-behavioral management intervention contributed to reduction of body mass index, irrespective of levothyroxine use. This finding suggests that moderately elevated levels of TSH are a consequence rather than cause of overweight and pharmacological treatment should be avoided.

2004 ◽  
Vol 39 (Supplement 1) ◽  
pp. S71
Author(s):  
S. Narwal ◽  
N. A. V. Matthews ◽  
H. Anhalt ◽  
S. Tan ◽  
G. Wetzler ◽  
...  

Author(s):  
E.E. Reiterer ◽  
K.M. Sudi ◽  
A. Mayer ◽  
C. Limbert-Zinterl ◽  
C. Stalzer-Brunner ◽  
...  

Author(s):  
Malgorzata Krzystek-Korpacka ◽  
Eliza Patryn ◽  
Irena Kustrzeba-Wojcicka ◽  
Joanna Chrzanowska ◽  
Andrzej Gamian ◽  
...  

2019 ◽  
Vol 2 (S1) ◽  
pp. 16-21 ◽  
Author(s):  
Nakamura T ◽  
Kawashima T ◽  
Dobashi M ◽  
Narita A ◽  
Bando H

Background: Authors have continued treating patients with obesity and metabolic syndrome by application of Low Carbohydrate Diet (LCD). Furthermore, we have continued presenting various reports about nutrition and educational guidance and developing LCD medically and socially through the activity of Japan LCD Promoting Association (JLCDPA). Study Protocol: Subjects enrolled were 2773 patients with obesity who received nutritional guidance in our clinic. Methods include i) weight reduction program on the intervention of LCD and guidance by registered dietitian nutritionist (RDN), ii) LCD with 33% of carbohydrate, and iii) Practice of guidance including self-monitoring, lifestyle, motivation, determination for the goal, evaluation. Results and Discussion: Nutritional guidance has been carried out on a regular basis by three RDNs. Weight reduction was: 10% or more was observed in 666 (24.0%), and 5.0 – 9.9% was in 863 (31.2%). In other words, the reduction of 5.0% or more was 55.2%, and 3.0% or more was 71.4%. Our nutritional guidance has been made as a manual for weight reduction program. It includes various factors, such as Self-Regulation Empowerment, cognitive behavioral therapy and motivational interviewing. These results would become basal and reference data for future research in the field of weight reduction.


Sign in / Sign up

Export Citation Format

Share Document