scholarly journals The Utility of Capsule Endoscopy in Patients under 50 Years of Age with Recurrent Iron Deficiency Anaemia: Is the Juice Worth the Squeeze?

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Prabhjot Singh Sidhu ◽  
Mark E. McAlindon ◽  
Kaye Drew ◽  
Reena Sidhu
Keyword(s):  
Iron Deficiency ◽  
Capsule Endoscopy ◽  
Iron Deficiency Anaemia ◽  
Significant Proportion ◽  
Deficiency Anaemia ◽  
Significant Pathology ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Background and Aims. The role of capsule endoscopy (CE) in the <50 years of age patients with iron deficiency anaemia (IDA) remains unclear. We aim to assess its utility in this cohort.Methods. All patients referred for CE for recurrent IDA were included retrospectively. Patients were divided into Group 1 (<50 years) and Group 2 (≥50 years).Results. There were 971 patients with recurrent IDA and 28% belonged to Group 1. The mean age was 40 years in this group with a DY of 28% (n=76). Significant diagnoses included erosions and ulcers (26%;n=71), small bowel (SB) angioectasia (AE) (10%;n=27), SB tumours (3%;n=7), Crohn’s disease (3%;n=7), SB bowel strictures (1%;n=3), and SB varices (1%;n=2). On logistic regression, the presence of diabetes (P=0.02) and the use of warfarin (P=0.049) was associated with increased DY. The DY in Group 2 was 38% which was significantly higher than in Group 1 (P=0.02). While SB tumours were equally common in both groups, AE was commoner in Group 2 (P<0.001).Conclusion. A significant proportion of patients <50 years are referred for CE. Although the DY is lower compared to those ≥50 years, significant pathology is found in this age group. CE is advisable in patients <50 years old with recurrent IDA and negative bidirectional endoscopies.

Iron Deficiency Anaemia and Child Development

2005 ◽  
Vol 17 (1) ◽  
pp. 19-21 ◽  
Author(s):  
T. Hokama ◽  
M. Gushi Ken ◽  
N. Nosoko
Keyword(s):  
Child Development ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Speech Development ◽  
Control Group ◽  
Deficiency Anaemia ◽  
Developmental Index ◽  
The Mean ◽  
Group 2 ◽  
Group 1

A developmental test was carried out to evaluate the effect of iron deficiency anaemia on child development by using Bailey Scale of Infant Development (BSID) and Enjoji Scale of Infant Analytical development (ESID). The subjects were 54 children, divided into three groups. Group 1 consisted of 15 infants with anaemia; Group 2: 10 infants with a past history of anaemia and Group 3: 29 healthy normal infants without anaemia formed the control group. The characteristics of infants and their family background were not different among the three groups except for the male/female ratio. The mean mental developmental index (MDI) and psychomotor developmental index (PDI) of Group 1 and Group 2 were lower than that of control group using the BSID test. The mean speech development quotients of Group 1 and Group 2 were lower than that of control group in ESID. These tendencies were observed after subjects were stratified by sex. Therefore, the results of the study suggests that iron deficiency anaemia may affect child development especially speech development. Asia Pac J Public Health 2005: 17(1): 19-21.

scholarly journals Study of Role of Iron Deficiency Anaemia in Febrile Seizures in Children in a Tertiary Care Centre

2016 ◽  
Vol 35 (2) ◽  
pp. 148-151
Author(s):  
Bheema Naik Sreenivasa ◽  
Gowripura Visweswaraiah Kumar ◽  
Bheema Naik Manjunatha
Keyword(s):  
Risk Factor ◽  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Febrile Seizures ◽  
Deficiency Anemia ◽  
Age Group ◽  
Febrile Convulsions ◽  
Deficiency Anaemia ◽  
The Mean

Introduction: The world health organization estimates that anaemia largely caused by iron deficiency, affecting between 500 million and two billion people worldwide. Considering the age prevalence of iron deficiency anaemia and febrile convulsion which are the same, the role of iron in the metabolism of neurotransmitter and some enzymes, the function of hemoglobin in conveying oxygen to the brain and since fever can exacerbate symptoms that result from anaemia, a relationship between iron deficiency anaemia and febrile convulsions is probable. Some studies have suggested iron deficiency as a predisposing factor for febrile seizures. We designed this case control study to evaluate the relationship between iron deficiency anaemia and febrile convulsions. The objective of this study was to study the role of iron deficiency as a risk factor for febrile seizures.Materials and Methods: Hundred cases and 100 controls were included in the study. Cases were children of age group six months to six years presenting with febrile seizures. Controls were children of same age group presenting with febrile illness but without any seizures. After informed consent, detailed history was taken and clinical examination done in both cases and controls and blood investigations were done to diagnose iron deficiency anemia. Two groups were matched for age and sex. In all children hemoglobin (Hb) level, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), red cell distribution width (RDW) and plasma ferritin (PF) were determined and the data collected were analyzed statistically.Results: The mean PF was significantly lower in cases compared to controls (p=0.000) and RDW was significantly higher in cases compared to controls (p=0.00). The mean Hb%, MCV, MCH are lower in cases compared to controls but it was statistically not significant.Concluson: Iron deficiency is a significant risk factor for febrile seizures in children of age group six months to six years. Early detection and timely correction of iron deficiency may be helpful for prevention of febrile seizures in children.J Nepal Paediatr Soc 2015;35(2):148-151

scholarly journals Severe iron-deficiency anaemia due to hookworm infection diagnosed by capsule endoscopy

2021 ◽  
Vol 104 ◽  
pp. 271-272
Author(s):  
Hasna Chergui ◽  
Mohammad Akhoundi ◽  
Anthony Marteau ◽  
Bakhtiar Bejou ◽  
Celine Lekhal ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Capsule Endoscopy ◽  
Iron Deficiency Anaemia ◽  
Hookworm Infection ◽  
Deficiency Anaemia

scholarly journals Evaluation of Iron Status, Haemoglobin and Protein Levels of Pregnant Women in Owerri Metropolis

2021 ◽  
pp. 36-43
Author(s):  
I. L. Okoroiwu ◽  
Jane Ugochi Chinedu-Madu ◽  
Emmanuel Ifeanyi Obeagu ◽  
C. C. N. Vincent ◽  
O. M. T. B. Ochiabuto ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Serum Iron ◽  
Iron Deficiency Anaemia ◽  
Iron Status ◽  
Second Trimester ◽  
Protein Levels ◽  
Group 3 ◽  
The Mean ◽  
Group 2 ◽  
Group 1

The study was done to determine iron status, haemoglobin and protein levels of pregnant women in owerri metropolis. A total of 100 pregnant women were recruited for this study. The mean Hb levels in group 1, group 2, and group 3· were 12.00±1.68g/dl, 10.06±1.J4g/dl and 10.96±1.19g/dl respectively. The mean Serum ferritin level of group 1 was 67.00±88.38ng/ml, group 2, 52.48±52.47ng/ml and group 3, 51.26±48.70ng/ml. The mean Serum iron in group 1, 2 and 3 were 46.72±16.41 g/dl, 79.59±63.24 g/dl and 83.35±53.04 g/dl respectively. In group 1, 2 and 3 the mean results. ( g/dl) of TIBC were 295.58 ± 109.53, 324.06 ± 178.00 and 319.88 ± 92.95 and % T.S (%) were 18.78 ± 11.77,26.59 ± 19.40 and 17.97 ± 10.87 percent respectively. The mean total protein was group 1,6.83±l1.77g/dl, group 2,6.39±0.70g/dl and group 3, 6.39 ±0.98 g/dl while the mean albumin (g/dl) in group 1, 2 and 3 were 4.84±0.47, 4.13±0.28 and 4.14±0.29 respectively. The mean values of globulin (g/dl) were 1.98 ± 0.91, 2.29 ± 0.87 and 1.89 ± 0.90 in groups 1, 2 and 3 respectively. As gestational age increased; serum ferritin, total protein, and albumin levels decreased while serum" iron and TIBC increased. The differences in the mean results between the groups were statistically significant (p<0.05) while % T.S and globulin levels when compared showed no significant difference (p>0.05). Iron status showed no statistical difference with increasing parity (p>0.05). However, from this study iron deficiency anaemia was most prevalent in second trimester; hence iron status estimation should be an integral part of routine antenatal care test during second trimester of each pregnancy for proper assessment and management of iron deficiency anaemia in pregnancy.

scholarly journals Study of outcome of the treatment with intravenous iron sucrose in moderately anaemic pregnant women

2019 ◽  
Vol 8 (9) ◽  
pp. 3480
Author(s):  
Kohila Kalimuthu ◽  
Vanusha Avudaithangam
Keyword(s):  
Standard Deviation ◽  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anaemia ◽  
Intravenous Iron ◽  
Iron Sucrose ◽  
P Value ◽  
Deficiency Anaemia ◽  
The Mean ◽  
The Difference

Background: Moderate anaemia seen in about 15-20% of pregnant women. Iron sucrose complex which is used intravenously for the correction of Iron deficiency anaemia. The drug has been able to raise the haemoglobin to satisfactory level when used in moderately anaemic iron deficient pregnant women. The objective of this study was to study the improvement of Hb% after treatment with intravenous Iron sucrose complex in moderately anaemic pregnant women belonging to 24-32 weeks of gestational age.Methods: 50 antenatal patients between gestational age 24-32 weeks with hemoglobin between 8-9.5g/dl were selected and included in this study. They were subjected to blood hemoglobin estimation, hematocrit and peripheral smear study. In each infusion, the maximum total dose administered was 200 mg iron sucrose in 100 ml of normal saline, slow IV infused over 30 minutes. Monitoring was done throughout the infusion to observe for any side effects.Results: Mean hemoglobin among the 50 patients before starting the therapy was 8.172g/dl and the mean hemoglobin at the end of one month of completing the therapy was 11.066g/dl. The rise in mean hemoglobin i.e. the difference in the mean hemoglobin before and after treatment was 2.894g/dl. The p value is 0.0001 which is statistically significant. The mean hematocrit of the 50 patients studied before starting the treatment was 26.772% with a standard deviation of 1.914. The mean hematocrit after completing the therapy was 33.872% with a standard deviation of 1.321. The difference in the mean hematocrit was 7.100% with a p value of 0.0001 which is statistically significant.Conclusions: Intravenous iron sucrose complex is well tolerated and highly efficacious in improving hemoglobin, hematocrit in the treatment of iron deficiency anaemia in antenatal women.

scholarly journals Role of faecal occult bloods in the diagnosis of iron deficiency anaemia

2014 ◽  
Vol 5 (4) ◽  
pp. 231-236 ◽  
Author(s):  
A T M Dilshad Chowdhury ◽  
Gaius Longcroft-Wheaton ◽  
Andrew Davis ◽  
David Massey ◽  
Patrick Goggin
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anaemia ◽  
Deficiency Anaemia ◽  
Faecal Occult
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