scholarly journals Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Gaurang Modi ◽  
Irappa Madabhavi ◽  
Harsha Panchal ◽  
Apurva Patel ◽  
Asha Anand ◽  
...  
Keyword(s):  
Female Patient ◽  
Rare Case ◽  
Bone Marrow Aspiration ◽  
Granulocytic Sarcoma ◽  
Myeloproliferative Disorders ◽  
Punch Biopsy ◽  
Myeloid Sarcoma ◽  
2D Echocardiography ◽  
Rare Case Report ◽  
Pharmaceutical Industries

Myeloid sarcoma (chloroma, granulocytic sarcoma, or extramedullary myeloid tumour) is an extramedullary mass forming neoplasm composed of myeloid precursor cells. It is usually associated with myeloproliferative disorders but very rarely may precede the onset of leukemia. Here, we are presenting a rare case of primary vaginal myeloid sarcoma in a geriatric female patient without initial presentation of acute myeloid leukemia (AML). A 68-year-old female patient with ECOG Performance Score of 1 presented with pervaginal bleeding for 20 days. On colposcopic examination, she was found to have mass in the anterior fornix of vagina. A punch biopsy specimen revealed chloromatous infiltration of the vagina. LCA (leukocyte common antigen), MPO (myeloperoxidase), and c-kit were strongly positive on IHC (immunohistochemistry). The patient’s routine blood investigations were normal including peripheral smear, lactose dehydrogenase, uric acid, 2D echocardiography, conventional cytogenetics, bone marrow aspiration, and biopsy. The patient was given 4 cycles of decitabine (Decitex, manufactured by Sun Pharmaceutical Industries Limited, India), 20 mg/m2for 5 days at an interval of 28 days. There was a partial response to decitabine according to RECIST criteria. As decitabine therapy was well tolerated, we are continuing in the same way until disease progression without any complications. The patient is undergoing regular follow-up at our centre.

scholarly journals Monoblastic Sarcoma- A Rare Case Report of Myeloid Sarcoma Variant

2021 ◽  
Author(s):  
Nupur Kaushik ◽  
Lalit Kumar ◽  
Pooja Agarwal ◽  
Harendra Kumar ◽  
Brijesh Sharma
Keyword(s):  
Rare Case ◽  
Histopathological Examination ◽  
Granulocytic Sarcoma ◽  
Myeloid Sarcoma ◽  
Cervical Region ◽  
Rare Manifestation ◽  
Rare Case Report ◽  
History Of ◽  
Immature Myeloid Cells ◽  
Normal Architecture

Myeloid sarcoma, also known as chloroma, granulocytic sarcoma, extramedullary Acute Myeloid Leukaemia (AML), myeloblastoma or extramedullary myeloid tumour, is a rare manifestation, characterised by the proliferation of immature myeloid cells, myeloblasts or monoblasts occurring as one or more tumour at an extramedullary site. It is associated with disruption of normal architecture of tissue in which it is found. Monoblastic sarcoma is a rare variant of myeloid sarcoma. Hereby, the authors report a rare case of primary monoblastic sarcoma in a 64-year-old male patient presented with complaint of swelling over right side lower cervical region. He had no history of AML. On physical examination, the swelling was over medial one-third of right clavicle measuring 6×5.8×3 cm. The swelling was excised and sent for histopathological examination, which was diagnosed as monoblastic sarcoma, and confirmed on immunohistochemistry.

scholarly journals Psoriasiform Mycosis Fungoides Involving the Face- A Rare Case Report

2021 ◽  
pp. 94-99
Author(s):  
N. R. Vignesh ◽  
Shreya Srinivasan ◽  
G. Sukanya ◽  
S. Arun Karthikeyan
Keyword(s):  
Case Report ◽  
Mycosis Fungoides ◽  
Rare Case ◽  
Cell Lymphoma ◽  
Punch Biopsy ◽  
Cutaneous T Cell Lymphoma ◽  
Rare Presentation ◽  
Rare Case Report ◽  
Atypical Cells ◽  
The Face

Mycosis fungoides is represented as the most common epidermotropic cutaneous T-cell lymphoma, which is mainly characterized by the proliferation of atypical cells within the epidermis. We report a rare presentation of mycosis fungoides in a 60-year-old male presenting with chronic psoriasiform plaque involving the face. Punch biopsy of the lesion from the forehead was taken for routine histological examination and immunohistochemical stains. Results of biopsy and immunohistochemical findings were consistent with mycosis fungoides and diagnosed as psoriasiform presentation of mycosis fungoides involving the face.

scholarly journals Isolated myeloid sarcoma of lumbar spine without bone marrow involvement: a rare case report and treatment dilemma

2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
Janpreet S. Bhandohal ◽  
Leila Moosavi ◽  
Igor Garcia-Pacheco ◽  
Gian Yakoub ◽  
Rahul D. Polineni ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Lumbar Spine ◽  
Rare Case ◽  
Bone Marrow Involvement ◽  
Myeloid Sarcoma ◽  
Rare Case Report

scholarly journals Extramedullary Monoblastic Sarcoma/Myeloid Sarcoma of Paraspinal Region Without Myeloid Leukemia: A Rare Case Report

2018 ◽  
Vol 150 (suppl_1) ◽  
pp. S49-S50
Author(s):  
Mitul Modi ◽  
Vipulkumar Prajapati ◽  
Irappa Madabhavi ◽  
Himanshu Kavani ◽  
Mansi Shah
Keyword(s):  
Case Report ◽  
Myeloid Leukemia ◽  
Rare Case ◽  
Myeloid Sarcoma ◽  
Rare Case Report

scholarly journals Tuberculous Uveitis, Erythema Induratum, and Persistent Genital Warts in a Female Patient: A Rare Case Report

2019 ◽  
Vol 8 (1) ◽  
pp. 70
Author(s):  
Pedram Alirezaei ◽  
MohammadMahdi Majzoobi ◽  
Siamak Akbarzadeh ◽  
Golnoush Ebrahimi ◽  
HamidReza Ghasemibasir
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Rare Case ◽  
Genital Warts ◽  
Tuberculous Uveitis ◽  
Rare Case Report

Myeloid Sarcoma of the Breast of A Young Boy: A Case Report

2018 ◽  
Vol 2 (02) ◽  
pp. 61-63
Author(s):  
Huque Mahfuz ◽  
Mohammad Elias Hossain ◽  
Mohammed Mosleh Uddin ◽  
Md Mostafil Karim ◽  
Md Golam Robbani
Keyword(s):  
Granulocytic Sarcoma ◽  
Myeloproliferative Disorders ◽  
Diagnostic Techniques ◽  
Left Breast ◽  
The Body ◽  
Myeloid Sarcoma ◽  
Rare Entity ◽  
Resonance Imaging ◽  
Rare Tumour ◽  
Clinical Presentations

Granulocytic sarcoma also called myeloid sarcoma (MS) is an extramedullary tumour of immature granulocytic cells. It is a rare entity and most frequently associated with acute myeloid leukaemia (AML) but can occur with other myeloproliferative disorders. It may occur at any site, leading to very varied clinical presentations. Although it can occur in a number of areas of the body, the involvement of the breast is uncommon. We present a rare case of MS in a 14?year?old boy with a non-tender lump in the left breast that had been apparent for five months. Available diagnostic techniques, including ultrasound and magnetic resonance imaging were systematically performed. After mastectomy, biopsy and immunohistochemistry was done. Immuno-histochemical stains were positive for CD45 (haematological marker) and myeloid markers, such as myeloperoxidase (MPO), and CD68, CD43 suggesting the diagnosis of MS. Although MS is a rare tumour in breast and its diagnosis is usually difficult, the clinician must know about its existence to make differential diagnosis.

scholarly journals Nasopharyngeal angiofibroma in an elderly female patient: A rare case report

2018 ◽  
Author(s):  
Massimo Ralli ◽  
Massimo Fusconi ◽  
Irene Visconti ◽  
Salvatore Martellucci ◽  
Marco de Vincentiis ◽  
...  
Keyword(s):  
Case Report ◽  
Female Patient ◽  
Rare Case ◽  
Nasopharyngeal Angiofibroma ◽  
Elderly Female ◽  
Rare Case Report

Granulocytic Sarcoma of Ovary Associated with Chronic Myelogenous Leukaemia Mimicking Carcinoma: A Rare Case Report

2016 ◽  
Vol 3 (2) ◽  
pp. 1-5
Author(s):  
Diptirani Samanta ◽  
Tapan Sahoo ◽  
K Roopesh ◽  
Kirti Mohanty ◽  
Chaitali Bose ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Chronic Myelogenous Leukaemia ◽  
Granulocytic Sarcoma ◽  
Myelogenous Leukaemia ◽  
Rare Case Report

scholarly journals Waldenstroms Macroglobulinemia- Diagnostic difficulties- a rare case report

2019 ◽  
Vol 18 (3) ◽  
pp. 656-659
Author(s):  
Majed Momin ◽  
Anamika Aluri
Keyword(s):  
Bone Marrow ◽  
Flow Cytometry ◽  
B Cell ◽  
Rare Case ◽  
Medical Science ◽  
Bone Marrow Aspiration ◽  
Cell Neoplasm ◽  
Rare Case Report ◽  
Diagnostic Difficulties ◽  
Lymphoplasmacytic Infiltration

Waldenstrom’s macroglobulinemia(WM) is a B-cell neoplasm characterized by infiltration of the bone marrow by a lymphoplasmacytic infiltrate and an IgM monoclonal gammopathy. We report a rare case of a 72 year-old male who presented with fever, shortness of breath for one month. Examination revealed cervical and axillary lymphadenopathy with mild hepatomegaly. On evaluation, peripheral smear show significant rouleaux formation & bone marrow aspiration showed lymphoplasmacytic infiltration. Flow cytometry on bone marrow apirate suggestive of B cell neoplasm and serum protein electophoresis & Immunofixation study confirms diagnosis of waldenstroms macroglobulinemia. We report this case to emphasize diagnostic difficulties in diagnosis of waldenstorms macroglobulinemia and application of flow cytometry and immunofixation study for further confirmation and treatment. Bangladesh Journal of Medical Science Vol.18(3) 2019 p.656-659

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