Myeloid Sarcoma of the Breast of A Young Boy: A Case Report

2018 ◽  
Vol 2 (02) ◽  
pp. 61-63
Author(s):  
Huque Mahfuz ◽  
Mohammad Elias Hossain ◽  
Mohammed Mosleh Uddin ◽  
Md Mostafil Karim ◽  
Md Golam Robbani
Keyword(s):  
Granulocytic Sarcoma ◽  
Myeloproliferative Disorders ◽  
Diagnostic Techniques ◽  
Left Breast ◽  
The Body ◽  
Myeloid Sarcoma ◽  
Rare Entity ◽  
Resonance Imaging ◽  
Rare Tumour ◽  
Clinical Presentations

Granulocytic sarcoma also called myeloid sarcoma (MS) is an extramedullary tumour of immature granulocytic cells. It is a rare entity and most frequently associated with acute myeloid leukaemia (AML) but can occur with other myeloproliferative disorders. It may occur at any site, leading to very varied clinical presentations. Although it can occur in a number of areas of the body, the involvement of the breast is uncommon. We present a rare case of MS in a 14?year?old boy with a non-tender lump in the left breast that had been apparent for five months. Available diagnostic techniques, including ultrasound and magnetic resonance imaging were systematically performed. After mastectomy, biopsy and immunohistochemistry was done. Immuno-histochemical stains were positive for CD45 (haematological marker) and myeloid markers, such as myeloperoxidase (MPO), and CD68, CD43 suggesting the diagnosis of MS. Although MS is a rare tumour in breast and its diagnosis is usually difficult, the clinician must know about its existence to make differential diagnosis.

scholarly journals Primary Myeloid Sarcoma of the Ileum and Mesentery Causing Small Bowel Obstruction: Case Report and Literature Review

2020 ◽  
Vol 19 (1-2) ◽  
pp. 55-61
Author(s):  
Andrej Nikolovski ◽  
Dragoslav Mladenovikj ◽  
Aleksandra Veljanovska ◽  
Gordana Petrusevka
Keyword(s):  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Bowel Obstruction ◽  
Myeloid Leukemia ◽  
Young Male ◽  
Granulocytic Sarcoma ◽  
The Body ◽  
Myeloid Sarcoma ◽  
Immunohistochemistry Analysis ◽  
Palpable Tumor

Myeloid sarcoma (extramedullary myeloblastoma, granulocytic sarcoma, chloroma) is an extramedullary isolated malignant tumor of myeloblasts and immature myelocytes. It can occur anywhere in the body as a solitary tumor or can be accompanied with acute myeloid leukemia. We are presenting a case of a young male patient that presented with sings of a small bowel obstruction and a palpable tumor mass in the abdomen. After uneventful postoperative period, the immunohistochemistry analysis reported an extramedullary myeloid sarcoma since a normal bone marrow biopsy was revealed.

scholarly journals A Case Report of Primary Brain Hydatid Cyst in a Child

2020 ◽  
Vol 6 (1) ◽  
pp. 41-48
Author(s):  
Deepak Garg ◽  
◽  
Gaurav Jain ◽  
Virendra Sinha ◽  
◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Female Child ◽  
The Body ◽  
Body Parts ◽  
Resonance Imaging ◽  
Limb Weakness ◽  
Case Presentation ◽  
Clinical Presentations ◽  
Magnetic Resonance Imaging Mri ◽  
The Brain

Background and Importance: Hydatid cyst is endemic in India, with different clinical presentations according to the site of involvement in the body. However, its occurrence in the brain without the involvement of other body parts is rare. Case Presentation: An eight-year-old female child presented with right-sided limb weakness and slurring of speech. The diagnosis of primary brain hydatid cyst was made with Magnetic Resonance Imaging (MRI) of the brain. The cyst was removed completely, resulting in improved post-operative slurring of speech and limb weakness. Conclusion: In countries where hydatid disease is endemic, brain hydatidosis should on top of the differential diagnoses for intracerebral cystic lesions and managed as per hydatid protocol until proved otherwise. This approach is critical to prevent rupture and dissemination.

scholarly journals Male with myelofibrosis and ulceronecrotic lesions

2018 ◽  
Vol 64 (12) ◽  
pp. 1073-1074
Author(s):  
Flávia da Silva Domingos Santos ◽  
Priscila Vinhal Grupioni ◽  
Loan Towersey ◽  
Fred Bernardes Filho
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Acute Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Myelodysplastic Syndromes ◽  
Past History ◽  
Granulocytic Sarcoma ◽  
Myeloproliferative Disorders ◽  
Rare Entity ◽  
History Of ◽  
Acute Myeloid

SUMMARY Granulocytic sarcoma also called myeloid sarcoma is an extramedullary tumour of immature granulocytic cells. It is a rare entity, and mostly accompanied by acute myeloid leukaemia. It is observed during the course of myeloproliferative disorders especially in chronic myeloid leukaemia and myelodysplastic syndromes. Here, we report a case of a 60-year-old male with past history of myelofibrosis admitted to the emergency room due ulceronecrotic lesions, fever and dysphagia. We emphasize the importance of recognizing this entity and its severity.

scholarly journals Radiological and clinical patterns of myeloid sarcoma

2019 ◽  
Vol 53 (2) ◽  
pp. 213-218 ◽  
Author(s):  
Hans-Jonas Meyer ◽  
Maximilian Beimler ◽  
Gudrun Borte ◽  
Wolfram Pönisch ◽  
Alexey Surov
Keyword(s):  
Clinical Symptoms ◽  
Rare Complication ◽  
Granulocytic Sarcoma ◽  
Initial Diagnosis ◽  
The Body ◽  
Myeloid Sarcoma ◽  
Imaging Features ◽  
Hematological Disease ◽  
Large Patient ◽  
Underlying Malignancy

Abstract Background Myeloid sarcoma (MS), also known as granulocytic sarcoma or chloroma, is a solid tumor of extramedullary localization composed of malignant primitive myeloid cells. The purpose of the study was to identify clinical and imaging features in a large patient sample. Patients and methods Overall, 71 cases (34 females (47.9%) and 37 males (52.1%) with a median age of 56 (± 16 years) of histopathologically confirmed myeloid sarcoma were included into this study. The underlying hematological disease, occurrence, localizations and clinical symptoms as well as imaging features on computed tomography and magnetic resonance imaging were investigated. Results In 4 cases (5.63%) the manifestation of MS preceded the systemic hematological disease by a mean value of 3.8 ± 2.1 months. In 13 cases, first presentation of MS occurred simultaneously with the initial diagnosis of leukemia, and 51 patients presented MS after the initial diagnosis of the underlying malignancy with a mean latency of 39.8 ± 44.9 SD months. The visceral soft tissue was affected in 26 cases, followed by the cutis/subcutis was affected in 21 cases. Further localizations were bones (n = 13), central nervous system (n = 9), lymph nodes (n = 4) and visceral organs (n = 9). Conclusions MS is a rare complication of several hematological malignancies, predominantly of acute myeloid leukemia, which can affect any part of the body. In most cases it occurs after the diagnosis of the underlying malignancy, and affects frequently the cutis and subcutis.

scholarly journals Epitheloid hemangio-endothelioma of right aryepiglottic fold: a rare case report with review of literature

2015 ◽  
Vol 1 (2) ◽  
pp. 93
Author(s):  
Alpesh D. Fefar ◽  
Paresh J. Khavdu ◽  
Mukesh N. Dodia ◽  
Sejal N. Mistry ◽  
Manish R. Mehta
Keyword(s):  
Rare Case ◽  
Single Case ◽  
The Body ◽  
Rare Entity ◽  
Review Of Literature ◽  
Rare Tumour ◽  
Aryepiglottic Fold ◽  
First Case ◽  
Rare Case Report ◽  
Vascular Origin

<p class="abstract"><span lang="EN-US">Epitheloid hemangio-endothelioma is a very rare tumour of intermittent malignancy of vascular origin, having a tendency to recur with rare incidence of metastasis. The tumour is intermediate between haemangioma and angiosarcoma, mainly affecting liver, lung as well as bones, skin, penis, ovary, scalp, or any part of the body. Internet search was made with the key words epitheloid hemangio-endothelioma and epitheloid hemangio-endothelioma of Larynx, since now only single case has been reported from larynx involving subglottis. Hence we report this rare entity with involvement of the larynx (Sub site: Rt. Aryepiglottic fold) describing clinical and histopathological characteristic. This is perhaps the first case of epitheloid hemangio-endothelioma involving aryepiglottic fold.</span></p>

scholarly journals Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Gaurang Modi ◽  
Irappa Madabhavi ◽  
Harsha Panchal ◽  
Apurva Patel ◽  
Asha Anand ◽  
...  
Keyword(s):  
Female Patient ◽  
Rare Case ◽  
Bone Marrow Aspiration ◽  
Granulocytic Sarcoma ◽  
Myeloproliferative Disorders ◽  
Punch Biopsy ◽  
Myeloid Sarcoma ◽  
2D Echocardiography ◽  
Rare Case Report ◽  
Pharmaceutical Industries

Myeloid sarcoma (chloroma, granulocytic sarcoma, or extramedullary myeloid tumour) is an extramedullary mass forming neoplasm composed of myeloid precursor cells. It is usually associated with myeloproliferative disorders but very rarely may precede the onset of leukemia. Here, we are presenting a rare case of primary vaginal myeloid sarcoma in a geriatric female patient without initial presentation of acute myeloid leukemia (AML). A 68-year-old female patient with ECOG Performance Score of 1 presented with pervaginal bleeding for 20 days. On colposcopic examination, she was found to have mass in the anterior fornix of vagina. A punch biopsy specimen revealed chloromatous infiltration of the vagina. LCA (leukocyte common antigen), MPO (myeloperoxidase), and c-kit were strongly positive on IHC (immunohistochemistry). The patient’s routine blood investigations were normal including peripheral smear, lactose dehydrogenase, uric acid, 2D echocardiography, conventional cytogenetics, bone marrow aspiration, and biopsy. The patient was given 4 cycles of decitabine (Decitex, manufactured by Sun Pharmaceutical Industries Limited, India), 20 mg/m2for 5 days at an interval of 28 days. There was a partial response to decitabine according to RECIST criteria. As decitabine therapy was well tolerated, we are continuing in the same way until disease progression without any complications. The patient is undergoing regular follow-up at our centre.

Adenoid Cystic Carcinoma of the Breast detected with Contrast-Enhanced Spectral Mammography: A Case Report

2020 ◽  
Vol 16 ◽  
Author(s):  
Yun-Chung Cheung ◽  
Shir-Hwa Ueng ◽  
Shu-Hang Ng ◽  
Wen-Lin Kuo
Keyword(s):  
Left Breast ◽  
Breast Cancers ◽  
Resonance Imaging ◽  
Carcinoma Of The Breast ◽  
Outer Quadrant ◽  
Additional Information ◽  
Adenoid Cystic ◽  
Modern Technique ◽  
Contrast Enhanced ◽  
Rim Enhancement

Background: Contrast-enhanced spectral mammogram (CESM) is a modern technique providing additional information to detect or diagnose the breast cancers. Introduction: We present a rare ACC of breast on CESM. Methods: A 49-year-old woman with surgicopathological proved ACC is reported with features on CESM, sonography and contrast-enhanced magnetic resonance imaging (CE-MRI). Results: Sonography revealed a 1.4 cm × 1.2 cm × 1 cm circumscribe round mass in the upper outer quadrant of the left breast that was diagnosed to fibroadenoma. The mammogram did not show any discernible mass, however the recombined subtracted images displayed a circumscribe mass with thin rim enhancement and enhanced internal patches that were resembling to CE-MRI. Finally, the mass was proved to ACC. Conclusion: CESM facilitates detection of an isodense cancer and provides the enhanced features for differential diagnosis. Resembling CE-MRI, CESM displayed rim enhancement and internal enhanced patches as diagnostic clues for this case of ACC.

Magnetic Resonance Imaging in the Diagnosis of Disruption of the Posterior Tibial Tendon

Foot & Ankle ◽  
1987 ◽  
Vol 8 (3) ◽  
pp. 144-147 ◽  
Author(s):  
Ian J. Alexander ◽  
Kenneth A. Johnson ◽  
Thomas H. Berquist
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Soft Tissues ◽  
Diagnostic Technique ◽  
Clinical Findings ◽  
The Body ◽  
Posterior Tibial Tendon ◽  
Resonance Imaging ◽  
Posterior Tibial ◽  
Magnetic Resonance Imaging Mri

Magnetic resonance imaging (MRI), a useful technique of studying soft tissues of the body, can be very effective in assessing the integrity of tendons. Usually a patient with a complete tear of the posterior tibial tendon has characteristic physical findings. In the patient presented, MRI demonstrated a complete disruption of the posterior tibial tendon, despite the absence of the commonly associated clinical findings. In view of the difficulties encountered with attempted tenography of the completely torn posterior tibial tendon, MRI provides a sensitive alternative diagnostic technique.

Bone-related disorders of the jaw: A clinico-radiological diagnostic algorithm

2021 ◽  
pp. 197140092199896
Author(s):  
Ahmed Abdel Khalek Abdel Razek
Keyword(s):  
Diagnostic Algorithm ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Specific Diagnosis ◽  
Clinical Presentations ◽  
Neoplastic Lesions ◽  
Lesion Extension ◽  
Magnetic Resonance Imaging Mri ◽  
The Relationship ◽  
Ct And Mri

Bone-related disorders of the jaw (BRDJ) include a spectrum of non-neoplastic and neoplastic lesions of the maxillofacial region that have been recently classified into fibro-osseous lesions, giant cell lesions and osseous tumours. The histopathological features of BRDJ can be similar and overlie each other. Imaging is important in order to reach a specific diagnosis. However, the appearance of BRDJ on imaging is non-specific in some cases. Computed tomography (CT) and magnetic resonance imaging (MRI) are used for accurate localisation, characterisation of the tumour matrix, delineation of the lesion extension and establishment of the relation of BRDJ to the surrounding structures. Imaging is usually done to detect the relationship with the adjacent surrounding vital structures and to diagnose aggressive forms, malignant transformation and associated syndromes. The correlation of the demographic findings, the location and the clinical presentations with the imaging features are important for the diagnosis of BRDJ. The proposed clinico-radiological diagnostic algorithm with CT and MRI helps a specific diagnosis to be reached in some cases.

Feeding gastrostomy stoma site cutaneous myiasis: a rare entity

2021 ◽  
Vol 14 (7) ◽  
pp. e244352
Author(s):  
Snehasis Das ◽  
Naveen Kumar Gaur ◽  
Oseen Hajilal Shaikh ◽  
Uday Shamrao Kumbhar
Keyword(s):  
Medical History ◽  
Percutaneous Endoscopic Gastrostomy ◽  
Metastatic Carcinoma ◽  
The Body ◽  
Rare Entity ◽  
Stoma Site ◽  
Endoscopic Gastrostomy ◽  
First Case ◽  
Cutaneous Myiasis

Infestation of any dead or necrotic tissues by the larvae of flies (maggots) is myiasis. This form of habitation is not restricted to any particular tissues in the body and can occur anywhere. However, myiasis at the surgical stoma site is very rare. We present a 55-year-old woman diagnosed with metastatic carcinoma of the oesophagus who underwent feeding gastrostomy (FG). The patient later presented with worms at the FG site. We removed the FG tube, cleared all the maggots, thoroughly cleaned the wound and placed a new FG tube. Although its occurrences have been reported enough in medical history, there are only two documented cases of percutaneous endoscopic gastrostomy stoma site myiasis. Hence, we present the first case in the literature of cutaneous myiasis around an FG stoma site.

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