scholarly journals Monoblastic Sarcoma- A Rare Case Report of Myeloid Sarcoma Variant

2021 ◽  
Author(s):  
Nupur Kaushik ◽  
Lalit Kumar ◽  
Pooja Agarwal ◽  
Harendra Kumar ◽  
Brijesh Sharma
Keyword(s):  
Rare Case ◽  
Histopathological Examination ◽  
Granulocytic Sarcoma ◽  
Myeloid Sarcoma ◽  
Cervical Region ◽  
Rare Manifestation ◽  
Rare Case Report ◽  
History Of ◽  
Immature Myeloid Cells ◽  
Normal Architecture

Myeloid sarcoma, also known as chloroma, granulocytic sarcoma, extramedullary Acute Myeloid Leukaemia (AML), myeloblastoma or extramedullary myeloid tumour, is a rare manifestation, characterised by the proliferation of immature myeloid cells, myeloblasts or monoblasts occurring as one or more tumour at an extramedullary site. It is associated with disruption of normal architecture of tissue in which it is found. Monoblastic sarcoma is a rare variant of myeloid sarcoma. Hereby, the authors report a rare case of primary monoblastic sarcoma in a 64-year-old male patient presented with complaint of swelling over right side lower cervical region. He had no history of AML. On physical examination, the swelling was over medial one-third of right clavicle measuring 6×5.8×3 cm. The swelling was excised and sent for histopathological examination, which was diagnosed as monoblastic sarcoma, and confirmed on immunohistochemistry.

scholarly journals Ameloblastic Transformation of a Primarily Diagnosed Dentigerous Cyst of Jaw- A Rare Case Report

2021 ◽  
pp. 90-94
Author(s):  
Bose Surajit ◽  
Bhakta Ipsita ◽  
Karar Chandan Kumar ◽  
Singh Dharvind Kumar ◽  
Banerjee Abhishek
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Histopathological Examination ◽  
Dentigerous Cyst ◽  
Facial Asymmetry ◽  
Biological Behavior ◽  
Unerupted Tooth ◽  
Patient Reported ◽  
Rare Case Report ◽  
History Of

The separation of the follicle from around the crown of an unerupted tooth causes formation of dentigerous cyst. It may undergo metaplasia in several cases. In this case a 30 year old female patient reported with a history of dentigerous cyst with respect to impacted 48. The swelling started growing gradually causing facial asymmetry. On intraoral examination the swelling seem to extend from 48 to 46 region and cortical plates were expanded. The histopathological examination revealed the sample to be cystic ameloblastoma (mural variety). This paper sends a message that the potential of a cyst should never be understated, instead it must be kept in an observation or understanding the biological behavior over a course of time.

scholarly journals Acute Myeloid Leukemia Presenting as Acute Bulbar Palsy

2014 ◽  
Vol 13 (4) ◽  
pp. 481-483
Author(s):  
Kiran Kumar Singal ◽  
Ajay Mittal ◽  
Rajni Aggarwal ◽  
Saurav Aggarwal ◽  
Rao Farman Khan ◽  
...  
Keyword(s):  
Brain Stem ◽  
Myeloid Leukemia ◽  
Medical Science ◽  
Granulocytic Sarcoma ◽  
Myeloid Sarcoma ◽  
History Of ◽  
The Central Nervous System ◽  
Immature Myeloid Cells ◽  
Laboratory Investigations ◽  
The Brain

Myeloid Sarcoma1 (also termed as chloroma, granulocytic sarcoma, extra medullary myeloid tumor) is a rare extra medullary tumor composed of immature myeloid cells (myeloblast)2. It is usually associated with leukemia or other myeloproliferative disorder. Myeloid Sarcoma in the central nervous system, around the brain stem is the commonest site of presentation and require high suspicion for diagnosis. We report a forty years male patient with history of dysphagia, dysphonia for last two months. MRI showed chloromas around the brain stem. Laboratory investigations revealed the presence of AML. This is a rare case of Myeloid Sarcoma around the brain stem in a patient of AML. DOI: http://dx.doi.org/10.3329/bjms.v13i4.16056 Bangladesh Journal of Medical Science Vol.13(4) 2014 p.481-483

scholarly journals A Rare Case of Polypoidal Cystitis in Adult without History of Prolong Catheterization

2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Mohd Azren ◽  
Mohd Nazli ◽  
Asmah Hanim
Keyword(s):  
Rare Case ◽  
Histopathological Examination ◽  
Obstructive Uropathy ◽  
Transitional Cell ◽  
Urinary Calculi ◽  
Bladder Mucosa ◽  
Indwelling Catheter ◽  
The Past ◽  
Rare Case Report ◽  
History Of

Introduction: Polypoidal cystitis is a rare lesion of the bladder mucosa characterized by benign exophytic inflammation,epithelial proliferation and development of polypoid mass without evidence of neoplasm histologically. Polypoid cystitis is rarely seen in patient without prolong used of indwelling catheter. Other cases of polypoidal cystitis are associated with post-radiation, post chemotherapy bladder reaction, colovesicular fistula are extremely rare. Case Report: 66 year old Malay male ,underlying hypertension and Benign Prostatic Hyperplasia (BPH) on treatment, complaining of difficulty in urination, straining on voiding  for the past 6 months and on and off  hematuria for the past 2 months. He denied any history of CBD insertion or prolong cataheterization. Blood investigations are Normal. X-Ray KUB showed unremarkable. Ultrasound KUB revealed Prostatomegaly, no evidence of renal or ureteric calculi or evidence of Obstructive uropathy,No obvious bladder mass. Cystoscopy Examination (CE)  showed enlarged occlusive prostate and noted bladder growth at base of bladder. The growth is malignant looking however no active bleeding seen. No bladder stone seen. Patient subsequently underwent TransUrethral Resection of Bladder Tumor (TURBT) and Trans-Urethral Resection of Prostate (TURP) in same setting. Intra operatively was uneventful. HistoPathological Examination (HPE) from TURBT specimens showed in favour of Polypoidal Cystitis and  TURP revealed Nodular Hyperplasia. Discussion: Polypoidal Cystitis is a form or chronic cystitis characterized by exophytic inflammatory   lesion of bladder mucosa. The polypoidal mass is mimicking neoplasm. At the initial evaluation, it may be confused with transitional cell carcinoma of the urinary bladder, especially in patient without an indwelling catheter. The most common aetiology of this condition is long-standing indwelling catheterization.. There is also  reported that any factors that irritates the bladder mucosa may result in Polypoidal Cystitis.  In our patient ,there was no history of such other causes, including prolong catheterization, fistula, urinary calculi or radiation therapy.

scholarly journals Nevus Lipomatosus Cutaneous Superficialis with a Histopathological Appearance Resembling Sclerotic Fibroma: A Rare Case Report

2021 ◽  
Vol 9 (C) ◽  
pp. 246-249
Author(s):  
Rizka Ramadhani Ruray ◽  
Khairuddin Djawad ◽  
Airin Nurdin
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Histopathological Examination ◽  
Fat Cells ◽  
Morphological Abnormalities ◽  
Lower Back ◽  
Spray Method ◽  
Rare Case Report ◽  
Paraffin Block ◽  
History Of

Background: Nevus lipomatosus cutaneous superficialis (NLCS) of Hoffmann–Zurhelle is a benign idiopathic hamartoma. There are two types of NLCS, multiple and solitary. They are found in the abdomen, lower back, buttocks, hips, upper posterior thighs, and pelvis. The diagnosis can be evaluated with a typical histopathological of mature fat cells in the dermis, with 10%–50% of the dermis. Case Report: We reported a case of NLCS with clinical papules and multiple nodules on the buttocks since the age of 6 years with a history of lipoma removal. The dermoscopic examination was conducted to confirm the diagnosis. The histopathological examination showed a dominant sclerotic fibroma with two sessions of biopsy and a few mature fats on the dermis after deeper cuts paraffin block. Cryotherapy with an open spray method is treatment of choice in this patient. Discussion: The appearance of the dermis in NLCS can be normal or an increase in collagen. Interestingly, collagen has sclerosis partially and resembles sclerotic fibroma never been reported. NLCS increases the amount of collagen; however, collagen as sclerosis remains obscure. The features of NLCS histopathological with other morphological abnormalities in the dermis have been reported, such as NLCS with perifollicular fibroma (PF) features. The sclerotic fibroma features are other morphological abnormalities in NLCS, as reported in the PF.

scholarly journals Primary Vaginal Myeloid Sarcoma: A Rare Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Gaurang Modi ◽  
Irappa Madabhavi ◽  
Harsha Panchal ◽  
Apurva Patel ◽  
Asha Anand ◽  
...  
Keyword(s):  
Female Patient ◽  
Rare Case ◽  
Bone Marrow Aspiration ◽  
Granulocytic Sarcoma ◽  
Myeloproliferative Disorders ◽  
Punch Biopsy ◽  
Myeloid Sarcoma ◽  
2D Echocardiography ◽  
Rare Case Report ◽  
Pharmaceutical Industries

Myeloid sarcoma (chloroma, granulocytic sarcoma, or extramedullary myeloid tumour) is an extramedullary mass forming neoplasm composed of myeloid precursor cells. It is usually associated with myeloproliferative disorders but very rarely may precede the onset of leukemia. Here, we are presenting a rare case of primary vaginal myeloid sarcoma in a geriatric female patient without initial presentation of acute myeloid leukemia (AML). A 68-year-old female patient with ECOG Performance Score of 1 presented with pervaginal bleeding for 20 days. On colposcopic examination, she was found to have mass in the anterior fornix of vagina. A punch biopsy specimen revealed chloromatous infiltration of the vagina. LCA (leukocyte common antigen), MPO (myeloperoxidase), and c-kit were strongly positive on IHC (immunohistochemistry). The patient’s routine blood investigations were normal including peripheral smear, lactose dehydrogenase, uric acid, 2D echocardiography, conventional cytogenetics, bone marrow aspiration, and biopsy. The patient was given 4 cycles of decitabine (Decitex, manufactured by Sun Pharmaceutical Industries Limited, India), 20 mg/m2for 5 days at an interval of 28 days. There was a partial response to decitabine according to RECIST criteria. As decitabine therapy was well tolerated, we are continuing in the same way until disease progression without any complications. The patient is undergoing regular follow-up at our centre.

scholarly journals Fatal typhoid intestinal perforation in post tubal ligation death with an alleged medical negligence: a rare case report

2018 ◽  
Vol 7 (2) ◽  
pp. 755
Author(s):  
Pankaj Suresh Ghormade ◽  
Ajay Narmadaprasad Keoliya
Keyword(s):  
Typhoid Fever ◽  
Intestinal Perforation ◽  
Rare Case ◽  
Tubal Ligation ◽  
Medical Negligence ◽  
Free Perforation ◽  
Ileal Perforation ◽  
Rare Case Report ◽  
History Of ◽  
Difficult Challenge

Worldwide tubal sterilization is commonly used procedure for family planning method. Tubal ligation by minilaparotomy under local anaesthesia is most commonly used method of female sterilization in India. The death rate after tubal sterilizations is 72/100000 for all procedures and mainly due to general anaesthesia or vascular injuries. Iatrogenic injury to bowel can occur in minilaparotomy tubal ligations if there are dense adhesions of intestines or history of previous surgery. In the present case of interval post tubal ligation by minilaparotomy, fatal ileal perforation due to typhoid fever was detected on autopsy which was confirmed after complete histological and lab investigations. Atypical complications of typhoid fever were also noted. In developing countries, typhoid fever is the leading cause of non-traumatic free perforation of intestine and its incidence ranges from 0.9% to 39%, with a high mortality rate. This is rare case of an alleged medical negligence after surgery; in which deciding factor was cause of intestinal perforation i.e. iatrogenic or natural and it posed a difficult challenge.

scholarly journals Solitary Trichoepithelioma of Nose: A Rare Case Report and Review of Literature

2015 ◽  
Vol 6 (3) ◽  
pp. 115-117
Author(s):  
Sachin Lal Shilpakar ◽  
Bivek Aryal ◽  
Shyam Thapa Chettri ◽  
Apar Pokharel ◽  
Deepak Paudel
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Histopathological Examination ◽  
Hair Follicles ◽  
Review Of Literature ◽  
Solitary Lesion ◽  
Biological Potential ◽  
Rare Case Report ◽  
The Face ◽  
Head Neck

ABSTRACT The trichoepithelioma is a benign cutaneous neoplasm which is derived from hair follicles. It is common in the face, but there are only three reports of the solitary occurrence on the nose. It is often not recognized because of its rarity, controversial classification, origin and biological potential. The objective of this paper is to present a case of solitary trichoepithelioma on the nose, histopathological examination and treatment. It should be considered as a differential diagnosis of a solitary lesion of nose which is confused with basal cell carcinoma. The confirmation by histopathological examination is essential. How to cite this article Sah BP, Shilpakar SL, Aryal B, Chettri ST, Pokharel A, Mishra S, Paudel D. Solitary Trichoepithelioma of Nose: A Rare Case Report and Review of Literature. Int J Head Neck Surg 2015;6(3):115-117.

scholarly journals Non-painful severe variant form of eruptive lingual papillitis: A case report and literature review

2021 ◽  
Vol 13 (2) ◽  
Author(s):  
Manal Ahmed Halwani
Keyword(s):  
Emergency Department ◽  
Case Report ◽  
Literature Review ◽  
Oral Hygiene ◽  
Rare Case ◽  
Dorsal Surface ◽  
Variant Form ◽  
Girl Child ◽  
Rare Case Report ◽  
History Of

Eruptive lingual papillitis is a common benign disorder manifested by inflammation of fungiform papillae on the dorsolateral surface of the tongue. Several variants of lingual papillitis have been reported since 1997, most or all of them with painful erythematous papules. Here we report a case of 6 years old girl child with non-painful severe variant form of eruptive lingual papillitis presented to the emergency department. The entire dorsal surface of the tongue was surfaced by 2-3mm by multiple erythematous papules and some with a white or yellowish colour. The papules were excessively inflamed, pigmented, aggregated, and crusted. The cause was idiopathic which resolved within ten days. The parent and patient were reassured with advice to practice oral hygiene. This is a rare case report describing non-painful lingual papillitis without a history of any prior episodes.

scholarly journals Isolated myeloid sarcoma of lumbar spine without bone marrow involvement: a rare case report and treatment dilemma

2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
Janpreet S. Bhandohal ◽  
Leila Moosavi ◽  
Igor Garcia-Pacheco ◽  
Gian Yakoub ◽  
Rahul D. Polineni ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Lumbar Spine ◽  
Rare Case ◽  
Bone Marrow Involvement ◽  
Myeloid Sarcoma ◽  
Rare Case Report

scholarly journals A rare case of Gingival Myeloid sarcoma in a child

2017 ◽  
Vol 7 (2) ◽  
pp. 1227-1230
Author(s):  
Meghashree Vishwanath ◽  
Purnima S Rao ◽  
Muktha R Pai
Keyword(s):  
Lymph Node ◽  
Rare Case ◽  
Soft Tissues ◽  
Myeloid Cells ◽  
Myeloid Sarcoma ◽  
Rare Tumour ◽  
Immature Myeloid Cells

Myeloid sarcoma is a rare tumour composed of immature myeloid cells. Its occurrence in childhood is rare. Only a few cases of intraoral myeloid sarcoma have been reported in literature. We present a case of myeloid sarcoma with simultaneous involvement of intraoral soft tissues and lymph node. Here, importance is given to suspect this frequently misdiagnosed disease. 

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