scholarly journals A 12-Week Assessment of the Treatment of White Spot Lesions with CPP-ACP Paste and/or Fluoride Varnish

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Zeynep Aslı Güçlü ◽  
Alev Alaçam ◽  
Nichola Jayne Coleman
Keyword(s):  
Clinical Study ◽  
Oral Hygiene ◽  
Clinical Applications ◽  
Laser Fluorescence ◽  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions ◽  
Treatment Regimes ◽  
The Impact ◽  
Made In

This 12-week clinical study evaluated the impact of 10% CPP-ACP and 5% sodium fluoride varnish regimes on the regression of nonorthodontic white spot lesions (WSLs). The study included 21 children with 101 WSLs who were randomised into four treatment regimes: weekly clinical applications of fluoride varnish for the first month (FV); twice daily self-applications of CPP-ACP paste (CPP-ACP); weekly applications of fluoride varnish for the first month and twice daily self-applications of CPP-ACP paste (CPP-ACP-FV); and no intervention (control). All groups undertook a standard oral hygiene protocol and weekly consultation. Visual appraisals and laser fluorescence (LF) measurements were made in weeks one and twelve. The majority of WSLs in the control and FV groups exhibited no shift in appearance, whereas, in the CPP-ACP and CPP-ACP-FV groups, the lesions predominantly regressed. The visual and LF assessments indicated that the extent of remineralisation afforded by the treatments was of the following order: control ~ FV < CPP-ACP ~ CPP-ACP-FV. Self-applications of CPP-ACP paste as an adjunct to standard oral hygiene significantly improved the appearance and remineralisation of WSLs. No advantage was observed for the use of fluoride varnish as a supplement to either the standard or CPP-ACP-enhanced oral hygiene regimes.

scholarly journals Effect of Chlorhexidine Varnish and Fluoride Varnish on White Spot Lesions in Orthodontic Patients- a Systematic Review

2021 ◽  
Vol 15 (1) ◽  
pp. 151-159
Author(s):  
Aravinthrajkumar Govindaraj ◽  
S.P. Saravana Dinesh
Keyword(s):  
Systematic Review ◽  
Oral Hygiene ◽  
Orthodontic Treatment ◽  
Significant Risk ◽  
White Spot ◽  
Fluoride Varnish ◽  
Cochrane Library ◽  
White Spot Lesions ◽  
Manual Search ◽  
Orthodontic Patients

Aim: The aim of this study is to critically review the studies that studied the effect of Chlorhexidine varnish and fluoride varnish on White Spot Lesion (WSL) in patients undergoing orthodontic treatment. Materials and Methods: The electronic database PubMed, The Cochrane Library, Medline, Embase, Google Scholar, Web of Knowledge along with a complimentary manual search of all orthodontic journals till the first week of December 2019 was searched. English language study performed on humans, randomized or nonrandomized clinical trials, comparing the effect of fluoride and chlorhexidine varnish on WSL was included in the review. Quality assessment of included studies was performed. Clinical Significance: The need for an adjunct oral hygiene aid to reduce the incidence and prevalence of white spot lesions in orthodontic patients is necessary. The use of these varnishes will aid in the same and thus make the adverse effects of fixed orthodontic treatment negligible. Review of Literature: Enamel demineralization is a significant risk associated with orthodontic treatment when oral hygiene is poor. Prevention of demineralization during orthodontic treatment is one of the greatest challenges faced by clinicians despite modern advances in caries prevention. The development of White Spot Lesions (WSLs) is attributed to prolonged plaque accumulation around the brackets. Results: The search identified a total of 3 studies that were included in this review. One study had Low risk of bias and the remaining 2 studies had moderate overall risk. Results showed that there was a reduction in the incidence of white spot lesions in orthodontic patients after application of chlorhexidine and Fluoride varnish. Conclusion: Low level evidence is available to conclude that the use of chlorhexidine varnishes and fluoride varnishes reduces the prevalence of white spot lesions in patients undergoing fixed orthodontic treatment. Due to its limitations, the results of this systematic review should be handled with caution and further well-planned Randomized Clinical Trial (RCT) are needed to provide a discrete conclusion.

scholarly journals Effect of topical fluoride gel and fluoride varnish in the prevention of white spot lesions in patients undergoing fixed orthodontic treatment: An in vivo study

2022 ◽  
Vol 11 ◽  
pp. 301-308
Author(s):  
Vivek Kumar Thakur ◽  
Raghuvinder S. Vats ◽  
M. P. Prasanna Kumar ◽  
Sanjeev Datana ◽  
Mohit Sharma ◽  
...  
Keyword(s):  
Orthodontic Treatment ◽  
Visual Observation ◽  
Primary Objective ◽  
Laser Fluorescence ◽  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions ◽  
Orthodontic Bracket ◽  
Topical Fluoride

Objectives: Our primary objective was to establish the efficacy of fluoride gel and fluoride varnish in the prevention of white spot lesions (WSLs) development during fixed orthodontic treatment. Materials and Methods: The study sample consisted of 60 adult patients in a prospective split-mouth study design. Interventions, that is, topical fluoride gel and topical fluoride varnish were assigned at the time of bonding to either the right or left halves of the dentition. In all subjects, repeated evaluation of demineralization was done on the facial surfaces of sample teeth in each quadrant. Evaluation using laser fluorescence and by direct visual observation under magnification was carried out at bonding (T0), 3 months (T1), and 6 months (T2). Results: The distribution of mean DIAGNOdent score at T1 (3.14 ± 1.00 vs. 2.81 ± 0.852) and T2 (4.17 ± 1.41 vs. 3.51 ± 1.13) was observed which is significantly higher in the Gel group compared to the Varnish group. In the Gel group, the distribution of mean DIAGNOdent score at T1 (3.14 ± 1.00) and T2 (4.17 ± 1.41) is significantly higher compared to mean DIAGNOdent score at baseline T0 (2.07 ± 0.66). In the Varnish group, the distribution of mean DIAGNOdent score at T1 (2.81 ± 0.852) and T2 (3.51 ± 1.13) is significantly higher compared to the mean DIAGNOdent score at T0 (2.07 ± 0.66). Visual scores also correlated with DIAGNOdent scores. Conclusion: Fluoride varnish is more efficacious than fluoride gel in reducing enamel demineralization. Initial application of fluoride varnish around the orthodontic bracket at bonding appointment can offer significant protection against WSLs.

scholarly journals Efficacy of Fluoride Varnish and Cheese on White Spot Lesions Remineralization: Evaluation Using Laser Fluorescence

2018 ◽  
Author(s):  
Susi Sukmasari ◽  
Wan Nurfazliyana binti Wan Fauzi ◽  
Zati Balqis binti Mohammed Azme ◽  
Anisa Kusumawardani ◽  
Iswan Zuraidi Zainol
Keyword(s):  
Laser Fluorescence ◽  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions

Fluoride varnish for the prevention of white spot lesions during orthodontic treatment with fixed appliances: a randomized controlled trial

2019 ◽  
Vol 42 (3) ◽  
pp. 326-330 ◽  
Author(s):  
Mikael Sonesson ◽  
Anna Brechter ◽  
Salem Abdulraheem ◽  
Rolf Lindman ◽  
Svante Twetman
Keyword(s):  
Placebo Group ◽  
Orthodontic Treatment ◽  
Test Group ◽  
Ammonium Fluoride ◽  
Dropout Rate ◽  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions ◽  
Randomized Controlled ◽  
Fixed Appliances

Summary Background Self-applied and professional fluorides are key elements to limit caries-related side-effects during orthodontic treatment with fixed appliances. Objective To evaluate the effectiveness of a new fluoride varnish formula containing 1.5% ammonium fluoride in preventing white spot lesions (WSLs) in adolescents undergoing multi-bracket orthodontic treatment. Subjects and methods The study employed a randomized controlled triple-blinded design with two parallel arms. One hundred eighty-two healthy adolescents (12–18 years) referred to three orthodontic specialist clinics were eligible and consecutively enrolled. Informed consent was obtained from 166 patients and they were randomly allocated to a test or a placebo group (with aid of a computer program, generating sequence numbers in blocks of 15). In the test group, fluoride varnish was applied in a thin layer around the bracket base every sixth week during the orthodontic treatment, while patients in the placebo group received a varnish without fluoride. The intervention started at onset of the fixed appliances and continued until debonding. The endpoint was prevalence and severity of WSLs on the labial surfaces of the maxillary incisors, canines, and premolars as scored from high-resolution pre- and post-treatment digital photos with aid of a four-level score. Results One hundred forty-eight patients completed the trial, 75 in the test group and 73 in the placebo group (dropout rate 10.8%). The total prevalence of WSL’s on subject level after debonding was 41.8% in the test group and 43.8% in the placebo group. The number of patients exhibiting more severe lesions (score 3 + 4) was higher in the placebo group (P &lt; 0.05); the absolute risk reduction was 14% and the number needed to treat was 7.1. Limitations The multicentre design with somewhat diverging routines at the different clinics may have increased risk for performance bias. No health-economic evaluation was carried out. Conclusions Regular applications of an ammonium fluoride varnish reduced the prevalence of advanced WSL during treatment with fixed orthodontic appliances. Clinical trial registration ClinicalTrials.gov (NCT03725020). Protocol The protocol was not published before trial commencement.

scholarly journals Fluoride varnish may improve white spot lesions

2011 ◽  
Vol 12 (4) ◽  
pp. 104-105
Author(s):  
Gary L. Stafford
Keyword(s):  
White Spot ◽  
Fluoride Varnish ◽  
White Spot Lesions

A longitudinal laser fluorescence study of white spot lesions in orthodontic patients

1998 ◽  
Vol 113 (6) ◽  
pp. 595-602 ◽  
Author(s):  
Susan AI-Khateeb ◽  
Carl-Magnus Forsberg ◽  
Elbert de Josselin de Jong ◽  
Birgit Angmar-Månsson
Keyword(s):  
Laser Fluorescence ◽  
White Spot ◽  
White Spot Lesions ◽  
Fluorescence Study ◽  
Orthodontic Patients

scholarly journals Impact of Two Remineralizing Agents on White Spot Lesions

2020 ◽  
Author(s):  
Ebaa Ibrahim Alagha
Keyword(s):  
Mean Value ◽  
White Spot ◽  
Control Group ◽  
Main Concern ◽  
White Spot Lesions ◽  
Mean Values ◽  
Restorative Treatment ◽  
Significant Difference ◽  
Group B ◽  
The Impact

Abstract Aim of the study: This study evaluated the impact of two remineralizing agents containing casein phosphopeptideamorphous calcium phosphate (CPPACP), and Tricalcium phosphate (TCP) on white spot lesions. Materials and Methods: A total of ninety freshly extracted upper premolars were divided in three equal groups (30 each). Group A: Control group. Group B: Varnish containing CPP–ACP. Group C: Varnish containing TCP. The teeth were subjected to Diagnodent test after inducing white spot lesions to assess any surface changes present on the teeth. The readings were repeated post demineralization and post-remineralization. Results: Statistically significant difference was present in the mean values between the tested groups. CPP-ACP group recorded higher mean value at demineralization when compared to TCP group. Statistically significant difference (p < 0.0001) was present between the baseline and the demineralization values. CPP-ACP group presented higher remineralization results when compared to TCP group. T-test proved a significant difference between the tested groups. Conclusion: CPP-ACP containing varnish had higher remineralizing effect when compared to TCP containing varnish. Clinical Significance: Recently, the focus of restorative dentistry has been directed toward a conservative approach. Prevention and non-restorative treatment of initial enamel caries is the main concern. Remineralization procedures are the most preferred way of regeneration of lost tooth structure.

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