scholarly journals A Rare Case of Primary Bilateral Adrenal Lymphoma

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Veeraraghavan Meyyur Aravamudan ◽  
Phang Kee Fong ◽  
Yang Shiyao Sam ◽  
Pavel Singh ◽  
Siok-Bian Ng ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
B Cell Lymphoma ◽  
Primary Lymphoma ◽  
Chop Chemotherapy ◽  
Ct Guided ◽  
Large B Cell Lymphoma ◽  
Adrenal Lymphoma ◽  
Synacthen Test ◽  
Adrenal Masses ◽  
Short Synacthen Test

Lymphoma may involve the adrenal glands, but primary lymphoma is rare. Only a few cases have been reported in medical literature. Primary adrenal lymphoma is extremely rare, accounting for <1% of non-Hodgkin lymphomas. We here present a case of a middle-aged female who presented with persistent fever for three weeks. She also reported significant weight loss of more than 10 kgs over the duration of three months. Computed tomography of the thorax and abdomen and pelvis demonstrated bilateral adrenal masses. She underwent short Synacthen test which showed evidence of adrenal insufficiency. She underwent CT-guided adrenal gland biopsy. Histology of adrenal gland biopsy showed features consistent with diffuse large B-cell lymphoma. She was started on R-CHOP chemotherapy and had a good clinical response and remained in complete remission for five months after chemotherapy.

Complete remission of primary bilateral adrenal lymphoma achieved by Rituximab-CHOP chemotherapy

Open Medicine ◽  
2011 ◽  
Vol 6 (6) ◽  
pp. 778-782
Author(s):  
Yin-long Yang ◽  
Ting-ting Ye ◽  
Zhu-yin Wang ◽  
Er-li Gao ◽  
Lei-ping Wang ◽  
...  
Keyword(s):  
Complete Remission ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Chop Chemotherapy ◽  
Large B Cell Lymphoma ◽  
Clinical Presentations ◽  
Adrenal Lymphoma ◽  
Uncertain Etiology ◽  
Large B Cell

AbstractPrimary adrenal lymphoma (PAL) is an exceedingly rare disease. Because of its rareness, uncertain etiology, variable duration of survival, unremarkable clinical presentations and unsatisfied therapeutic strategies, its treatment has always been unsatisfactory. Here we report a 50-year-old male patient with primary bilateral adrenal diffuse large B-cell lymphoma. He was treated with surgery followed by combined chemotherapy using R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). He achieved complete remission after 3 cycles of chemotherapy. At present, he is considered free of tumor at 3 years after chemotherapy. Our case report demonstrates that patients with primary bilateral adrenal diffuse large B-cell lymphoma may achieve a good outcome using R-CHOP chemotherapy. To the best of our knowledge, our patient who achieved complete remission after R-CHOP chemotherapy has had the longest survival as published in the literature.

scholarly journals Primary Adrenal Diffuse Large B-cell Lymphoma: A Mini Review

2015 ◽  
Vol 7 (3) ◽  
pp. 65-68 ◽  
Author(s):  
Rajeev Parameswaran ◽  
Dedrick Kok Hang Chan ◽  
Poon Li Mei Michelle ◽  
Shi Wang
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Surgical Excision ◽  
Large B Cell Lymphoma ◽  
Pubmed Database ◽  
Adrenal Lymphoma ◽  
Adrenal Masses ◽  
Elevated Lactate ◽  
Large B Cell

ABSTRACT Background Primary adrenal diffuse large B-cell lymphoma are aggressive high grade lymphomas affecting elderly gentlemen and mostly present with bilateral enlarged adrenal masses associated with B symptoms, adrenal insufficiency and elevated lactate dehydrogenase. When imaged with CT or ultrasound, these lesions usually appear as heterogeneous complex large masses with low density. They appear metabolically active on PET scan. Confirmatory diagnosis is established by image guided biopsy or surgical excision. Treatment is usually with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP) or CHOP like regimes. Surgery has very limited role, if any in the management of this condition. The prognosis is generally poor with only about a third of patients achieving partial or complete remission following treatment. A concise review of the literature (PubMed database; 1990–2014) on the clinical management of primary adrenal lymphoma along with a case example is discussed. How to cite this article Parameswaran R, Chan DKH, Michelle PLM, Wang S. Primary Adrenal Diffuse Large B-cell Lymphoma: A Mini Review. World J Endoc Surg 2015;7(3):65-68.

scholarly journals Primary adrenal lymphoma: a case of hiccups

2020 ◽  
Vol 2020 (4-5) ◽  
Author(s):  
Kylan Pathmanathan ◽  
Venkata Kodali ◽  
Abdulrazak Mohamad
Keyword(s):  
Adrenal Insufficiency ◽  
Adrenal Glands ◽  
B Cell Lymphoma ◽  
Primary Adrenal Insufficiency ◽  
Primary Adrenal Lymphoma ◽  
Adrenal Biopsy ◽  
Large B Cell Lymphoma ◽  
Adrenal Lymphoma ◽  
Biochemical Evaluation ◽  
Adrenal Masses

Abstract Approximately 250 cases of primary adrenal lymphoma have been reported. We describe an unusual presentation of this condition. Our patient is a 65-year-old male whom presented to the emergency department with 4 days of severe persistent hiccups. He had lost 26 kg in weight in the preceding 4 months. Computed tomography abdomen revealed large invasive bilateral adrenal masses. Biochemical evaluation confirmed adrenal insufficiency. Hiccups resolved within 24 h of steroid replacement. Adrenal biopsy confirmed a diffuse large B-cell lymphoma. Hypotheses for the aetiology of his hiccups include diaphragmatic irritation and primary adrenal insufficiency. This case is interesting for its rarity involving bilateral adrenal glands, Addison’s disease from the primary adrenal tumour and rapid resolution of hiccups with corticosteroid therapy.

scholarly journals A rare case of primary adrenal lymphoma

Folia Medica ◽  
2021 ◽  
Vol 63 (3) ◽  
pp. 443-447
Author(s):  
Alexey V. Shabunin ◽  
Dmitry N. Grekov ◽  
Ivan N. Lebedinsky ◽  
Andrey I. Evsikov ◽  
Serghei Covantev ◽  
...  
Keyword(s):  
Adrenal Gland ◽  
Rare Case ◽  
Cell Lymphoma ◽  
Adrenal Incidentaloma ◽  
B Cell Lymphoma ◽  
Primary Adrenal Lymphoma ◽  
Large B Cell Lymphoma ◽  
Adrenocortical Adenomas ◽  
Abdominal Organs ◽  
Adrenal Lymphoma

Adrenal gland incidentaloma (incidental &ndash; sudden, accidental) is a mass of the adrenal gland(s), accidentally detected by an instru-mental examination conducted for other reasons. The frequency of detection of this pathology based on computer tomography of the abdominal organs is 0.5%&ndash;2%. In most cases, the mass is represented by adrenocortical adenomas without hormonal secretion. It is an extremely rare case (less than 1% of all cases) when the adrenal incidentaloma is a primary adrenal lymphoma, which accounts for 1% of all non-Hodgkin lymphomas and 3% of all extranodal lymphomas with a few cases reported in the literature. In our article, we present a case of left adrenal incidentaloma of the adrenal gland, which, during further observation and examination, increased in size, which was the reason for performing laparoscopic adrenalectomy. According to the results of the histological examination, the mass turned out to be diffuse large B-cell lymphoma.

scholarly journals Primary Maxillofacial Large B-Cell Lymphoma in Immunocompetent Patients: Report of 5 Cases

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Ines Velez ◽  
Maritzabel Hogge
Keyword(s):  
Cell Lymphoma ◽  
Rare Condition ◽  
B Cell Lymphoma ◽  
Lymph Node Involvement ◽  
Primary Lymphoma ◽  
Malignant Bone Tumors ◽  
Large B Cell Lymphoma ◽  
Node Involvement ◽  
Single Bone ◽  
Immunocompetent Patients

Lymphomas of the oral cavity represent 5% of all lymphomas. They usually occur in immunocompromised patients. Lymphoma arising within a single bone, without visceral or lymph node involvement, is known as primary intraosseous lymphoma. It is a rare condition and constitutes 3.1% of malignant bone tumors and 5% of extranodal lymphomas. Primary lymphoma of the jaw is seldom seen and it is often misdiagnosed. Clinically, the manifestations are usually similar to an odontogenic tumor, cyst, or infection. Radiographically it appears as a radiolucent area that may mimic endodontic lesion, periodontal pathology, or odontogenic cyst or tumor. The initial presentation is commonly followed by multiple unnecessary extractions and/or root canal treatments. We present five cases of rare primary lymphoma of the maxillofacial complex, four of them intraosseous.

Primary diffuse large B cell lymphoma of the optic chiasm in an immunocompetent patient

2021 ◽  
Vol 14 (7) ◽  
pp. e243307
Author(s):  
Orlando De Jesus ◽  
Christian Rios-Vicil ◽  
Frances M Gómez-González ◽  
Román Vélez
Keyword(s):  
B Cell ◽  
Clinical Course ◽  
Cell Lymphoma ◽  
Brain Mri ◽  
B Cell Lymphoma ◽  
Optic Chiasm ◽  
Immunocompetent Patient ◽  
Primary Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Primary lymphoma of the visual pathway is rare, especially at the chiasm. Very few cases have been reported. The lesion is frequently confused with an optic–hypothalamic glioma. A 55-year-old man was found disoriented at his home by a friend and evaluated with a brain MRI which demonstrated an expansile mass located at the optic chiasm and hypothalamus level. The principal differential was a high-grade hypothalamic glioma due to the contrast enhancement. A biopsy of the chiasmal lesion was performed. Histological diagnosis of the lesion was compatible with a diffuse large B cell lymphoma. He was started on methotrexate and rituximab; however, his clinical course kept deteriorating, and he died 64 days after his presentation. All prior cases of primary lymphoma of the chiasm are reviewed.

Pitfalls of Frozen Section in Gynecological Pathology: A Rare Case of Ovarian Lymphoma in an HIV-Positive Woman Resembling Dysgerminoma on Frozen Section

2018 ◽  
Vol 27 (4) ◽  
pp. 387-389 ◽  
Author(s):  
Qing Wang ◽  
Raul Rodriguez ◽  
Jenna Z. Marcus ◽  
Lisa Podolsky ◽  
Damali Campbell ◽  
...  
Keyword(s):  
B Cell ◽  
Rare Case ◽  
Cell Lymphoma ◽  
Frozen Section ◽  
B Cell Lymphoma ◽  
Hiv Positive ◽  
Primary Lymphoma ◽  
Positive Woman ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Primary lymphoma of the ovary, particularly in an HIV-positive woman, is exceptionally rare, and ovarian lymphoma may not be considered at the time of intraoperative consultation. In this article, we present a case in an HIV-positive woman thought to be a dysgerminoma at the time of frozen section, but which was found to be a diffuse large B-cell lymphoma of the ovary.

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