scholarly journals Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Sebahattin Destek ◽  
Vahit Onur Gul ◽  
Serkan Ahioglu ◽  
Kursat Rahmi Serin

Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast, and its etiology remains not fully elucidated. IGM is observed more often in patients with autoimmune disease. Hyperprolactinemia is observed during pregnancy, lactation, and a history of oral contraceptive use. A 39-year-old patient with no history of oral contraceptive use presented with complaints such as redness, pain, and swelling in her left breast. Ultrasound and magnetic resonance imaging (MRI) revealed a suspicious inflamed mass lesion. Core biopsy was performed to exclude breast cancer and to further diagnose. The breast abscess was drained and steroids were given for treatment. In order to monitor any progression during the three months of treatment, hormone levels were routinely examined. Prolactin level was above the reference range, and pituitary MRI revealed a pituitary prolactinoma. After treatment with prolactin inhibitors, IGM also improved with hyperprolactinemia. This report emphasizes attention to hyperprolactinemia in cases of IGM diagnosis and treatment.

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Takuji Ota ◽  
Toshiya Kamiyama ◽  
Takuya Kato ◽  
Takayuki Hanamoto ◽  
Kunihiro Hirose ◽  
...  

Abstract Background Hepatic cavernous hemangioma (CH) is the most common hepatic benign tumor. Most cases are solitary, asymptomatic, and found incidentally. In symptomatic cases with rapidly growing tumors and coagulopathy, surgical treatment is considered. In rare cases, diffuse hepatic hemangiomatosis (DHH) is reported as a comorbidity. The etiology of DHH is unknown. Case presentation A 29-year-old female patient had a history of endometriosis treated with oral contraceptives. Hepatic CH was incidentally detected in the segment IVa of the liver according to the Couinaud classification. Follow-up computed tomography (CT) and ultrasound sonography showed the growth of the lesion and formation of multiple new lesions near the first. Enhanced CT and magnetic resonance imaging (MRI) revealed that the new lesions were different from CH. Although oral contraceptives were stopped, all lesions grew in size. Malignancy and possibility of rupture of these tumors were considered due to the clinical course, and we opted for surgical removal of the tumors. Left liver lobectomy and cholecystectomy were performed. Surgical findings were small red spot spreading and a mass in segment IV of the liver. Pathological examination revealed a circumscribed sponge-like tumor with diffuse irregular extension to the adjacent area. Both of the lesions consisted of blood-filled dilated vascular spaces lined by flat endothelium without atypia. The diagnosis was hepatic CH with DHH. The patient was discharged on postoperative day 12 uneventfully. Conclusion We report the successful resection of CH with DHH. The case findings suggest a relationship between oral contraceptive use and enlargement of CH and DHH. Although DHH has been poorly understood, a few previously published cases reported DHH occurrence in patients using oral contraceptives. In such cases, the decision to perform surgical resection should be made after careful examination.


1970 ◽  
Vol 116 (531) ◽  
pp. 165-167 ◽  
Author(s):  
David B. Marcotte ◽  
Francis J. Kane ◽  
Paul Obrist ◽  
Morris A. Lipton

There have been many studies (3,15,4) on the effects of oral contraceptive hormonal agents, though relatively few have concerned themselves with the possible adverse emotional reactions accompanying their use. To date, seven women (8, 6, 5, 13) have had psychotic episodes in temporal association with drug use, one patient having reported two such episodes. Four of these seven women had a history of severe postpartum disturbance in the past, and two others had previous psychiatric illness. There have been reports of varying incidence of depression, anxiety, increased or decreased sexual desire and relief of premenstrual tension. We wish to present data from a pilot double blind study of one combination oral contraceptive.


2002 ◽  
Vol 62 (8) ◽  
pp. 750-757 ◽  
Author(s):  
L. A. J. Heinemann ◽  
M. A. Lewis ◽  
D. Kühl-Habich ◽  
W. Braendle ◽  
S. Moehner ◽  
...  

Reumatismo ◽  
2016 ◽  
Vol 68 (2) ◽  
pp. 97 ◽  
Author(s):  
J. Alungal ◽  
M.C. Abdulla ◽  
R. Narayan

A 25 year-old woman presented with a painful mass in the left breast, polyarthritis and erythema nodosum. Fine needle aspiration cytology led to a diagnosis of granulomatous mastitis. Oral prednisolone rapidly improved the arthritis and the erythema nodosum. Granulomatous mastitis is a very rare, chronic inflammatory disease and only ten patients with granulomatous mastitis with erythema nodosum and polyarthitis have been described.


2002 ◽  
Vol 62 (6) ◽  
pp. 566-573 ◽  
Author(s):  
L. A. J. Heinemann ◽  
M. A. Lewis ◽  
Dörthe Kühl-Habich ◽  
W. Braendle ◽  
Edeltraut Garbe ◽  
...  

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