scholarly journals Extended Cystogastrostomy with Hydrogen Peroxide Irrigation Facilitates Endoscopic Pancreatic Necrosectomy

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Mohamed O. Othman ◽  
Sherif Elhanafi ◽  
Mohammed Saadi ◽  
Christine Yu ◽  
Brian R. Davis
Keyword(s):  
Hydrogen Peroxide ◽  
Clinical Success ◽  
Medical Center ◽  
Major Complication ◽  
Retrospective Chart Review ◽  
Median Number ◽  
Endoscopic Necrosectomy ◽  
Mean Size ◽  
Cyst Cavity

Introduction. Walled-off pancreatic necrosis (WOPN) is a major complication of acute pancreatitis. We hypothesized that an extended (2 cm) cystogastrostomy opening combined with hydrogen peroxide irrigation can increase the success of endoscopic necrosectomy and decrease the number of required endoscopic interventions. The aim of the study is to assess the safety and feasibility of the technique in the management of WOPN. Methods. This is a retrospective chart review of all cases that underwent EUS with extended cystogastrostomy and hydrogen peroxide irrigation prior to necrosectomy in a tertiary referral medical center. Clinical success was defined as complete resolution of the cyst cavity or a cyst cavity less than 2 cm in size on follow-up imaging. Results. 19 patients satisfied the inclusion criteria. The mean size of the walled-off cavity was 11+0.9 cm. Technical success of the procedure was 100%. The median number of necrosectomy sessions was 2 (range 1 to 7). Cavity resolution was noted in 18 out of 19 patients resulting in a clinical success of 94.7%. The median follow-up period was 12 months. The adverse events rate in our cohort was 15.7%. Conclusion. Extended cystogastrostomy coupled with hydrogen peroxide irrigation of WOPN cavity is safe and feasible.

Late endoscopic evaluation of the ostium size after external dacryocystorhinostomy

2020 ◽  
pp. 112067212097604
Author(s):  
Reem R Al Huthail ◽  
Yasser H Al-Faky
Keyword(s):  
Chart Review ◽  
Retrospective Chart Review ◽  
Tertiary Hospital ◽  
Nasal Endoscope ◽  
Long Term Follow Up ◽  
Mean Size ◽  
External Dacryocystorhinostomy ◽  
The Mean

Objective: To evaluate the effect of chronicity on the size of the ostium after external dacryocystorhinostomy (DCR) with intubation. Methods: Design: A retrospective chart review of patients who underwent external DCR with intubation over 10 years from January 2003 at a tertiary hospital. All patients were recruited and examined with rigid nasal endoscope. Results: A total number of 66 (85 eyes) patients were included. The mean age at the time of evaluation was 53.1 years with gender distribution of 54 females (81.8 %). The mean duration ±SD between the date of surgery and the date of evaluation was 33.2 ± 33.6 (6–118 months). Our study showed an overall anatomical and functional success of 98.8% and 95.3%, respectively. The mean size of the ostium (±SD) was 23.0 (±15.7) mm2 (ranging from 1 to 80.4 mm2). The size of the ostium was not a significant factor for failure ( p = 0.907). No statistically significant correlation was found between the long-term duration after surgery and the size of the ostium ( R: 0.025, p = 0.157). Conclusions: Nasal endoscopy after DCR is valuable in evaluating the ostium with no observed potential correlation between the long-term follow-up after surgery and the size of the ostium.

scholarly journals 599. Dalbavancin Utilization in Rural Healthcare Setting: A Single Center Three Years’ Experience

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S362-S362
Author(s):  
Ahmad AlSalman ◽  
Craig P Worby ◽  
emma Considine ◽  
Ritika Zijoo ◽  
Colleen Kershaw
Keyword(s):  
Staphylococcus Aureus ◽  
Medical Center ◽  
Insurance Coverage ◽  
Retrospective Chart Review ◽  
Healthcare Setting ◽  
Single Center ◽  
Persons Who Inject Drugs ◽  
Loss To Follow Up ◽  
Medication Assisted Treatment

Abstract Background Dalbavancin is a second generation lipoglycopeptide, approved by the Food and Drug Administration (FDA) for treatment of acute bacterial skin and skin structure infections (ABSSSI). The weekly dosing of Dalbavancin has encouraged its off-label use to treat other severe infections, especially in patients deemed to be poor candidates for intravenous antimicrobial therapy through a long-term intravenous catheter. Methods Single center retrospective chart review of 33 patients who were planned to receive Dalbavancin between March 2015 and March 2019 at a rural medical center in New Hampshire. We reviewed demographics, indications, microbiological, intravenous drug use status and compliance data. Results Dalbavancin therapy was planned for 25/33 patients (75.75%) specifically due to safety concerns around use of a peripherally inserted central catheter (PICC) in Persons Who Inject Drugs (PWID). All 25 patients (75.75%) were actively injecting at the time of the infection with 16/33 patients (48.48%) receiving or newly enrolled in medication assisted treatment. The planned duration of therapy was not completed in 15/33 patients (45.45%) and all were PWID. 11/33 patients (33.3%) were lost to follow up. Additionally, 6 patients experienced insurance coverage issues or difficulty having peripheral access placed. The average driving distance between home and infusion suite was 47 miles. Methicillin Resistant Staphylococcus aureus (19/33) and Methicillin Susceptible Staphylococcus aureus (8/33) were the most commonly treated organisms and the average pathogen-directed therapy duration prior to starting Dalbavancin was 15 days. Conclusion Despite recent data suggesting that Dalbavancin therapy for PWID has good compliance rates in urban settings, our experience suggests that the same principle might not be true in rural settings as the non-compliance and loss to follow up rates were very high. Disclosures All Authors: No reported disclosures

scholarly journals Treatment of Advanced Oropharyngeal Cancers with Chemotherapy and Radiation

2003 ◽  
Vol 82 (5) ◽  
pp. 367-370 ◽  
Author(s):  
Maria M. LoTempio ◽  
Marilene B. Wang ◽  
Ahmad Sadeghi
Keyword(s):  
Los Angeles ◽  
Primary Tumor ◽  
Chart Review ◽  
Medical Center ◽  
Retrospective Chart Review ◽  
Concomitant Chemotherapy ◽  
Small Series ◽  
Lost To Follow Up ◽  
Base Of The Tongue

We conducted a retrospective chart review of treatment outcomes in 17 adults who had been selected to undergo concomitant chemotherapy and radiation (chemo/XRT) for late-stage oropharyngeal cancers. All patients had been treated at the West Los Angeles VA Medical Center between March 1, 1998, and Sept. 30, 2000. Nine patients had a primary tumor at the base of the tongue, five had a primary tumor in the tonsillar area, and three had a tumor that affected both sites. Of this group, 15 patients completed one to three cycles of chemo/XRT, and the remaining two died during therapy. At the most recent follow-up, 9 of the 17 patients (52.9%) were documented to still be alive; seven patients had earlier died as a result of their primary tumor or a distant metastasis, and one patient had been lost to follow-up after completing treatment. At study's end, the duration of post-treatment survival ranged from 2 to 36 months (mean: 12.5). Based on the results of our small series, we conclude that chemo/XRT is a valid alternative to surgery with postoperative radiation and to radiation alone. Chemo/XRT yields acceptable rates of local control and allows for organ preservation with tolerable side effects.

Multivariate dimensions of hemotologic chaos indices for responders versus non-responders of patients with myelodysplastic syndromes (MDS) after treatment with ptx/cipro/decadron: A qualitative study

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 17540-17540
Author(s):  
R. R. Huang ◽  
A. Raza
Keyword(s):  
Chaos Theory ◽  
Response Rate ◽  
Dimensional Space ◽  
Medical Center ◽  
Median Number ◽  
White Blood Count ◽  
3 Dimensional ◽  
The Mean ◽  
Lower Magnitude

17540 Background: In our clinical study of 35 MDS patients who were treated with PTX/Cipro/Decadron, there was an 80% response rate in terms of achieving improved hematopoiesis (responders) during a 4-week period. The primary question of interest was, “What were the hematologic dynamic patterns that transpired between patients who responded versus those who did not?” The purpose of this study was an attempt to answer this question by applying chaos theory to peruse the underlying patterns that may have prognosis utility. Methods: Responders and non-responders were identified and were matched by age, sex, and FAB type. Only those patients who have sufficient and complete hematologic evaluations after treatment with at least 6 months follow-up to derive stable chaotic indices were included. The resulted sample was 3 patients from the non-responded group and 4 patients from the responded group. The three selected hematoloic parametes were white blood count, hemoglobin and platelets. The selected chaos index to indicate its magnitude of across time was the fractal dimension that has three components, namely capacity, information and correlational. Results: The mean ages for the non-responders and responders were 68 and 65, respectively. The median number of weeks evaluated was 38 for the non-responders and 35 weeks for the responders. The three hematologic parameters were analyzed simultaneously in the form of 3-dimensional space. Table indicates the chaos fractal indices for the two groups. Conclusion: Across the three indices, non-responders have an average of 7.4 % larger than responders, suggesting the former exhibited a relatively higher degree of “chaos” than the latter. For prognosis purpose, this result also suggests that patients who exhibit lower magnitude of the chaotic phenomena, will have a higher probability of responding to therapy. This work was done while the authors were at Rush-Presbyterian-St.Luke’s Medical Center. [Table: see text] No significant financial relationships to disclose.

Factors Affecting Compliance With Myringotomy Tube Follow-up Care

2022 ◽  
pp. 000348942110722
Author(s):  
Helen H. Soh ◽  
Katherine R. Keefe ◽  
Madhav Sambhu ◽  
Tithi D. Baul ◽  
Dillon B. Karst ◽  
...  
Keyword(s):  
Medical Center ◽  
Private Insurance ◽  
Academic Medical Center ◽  
Tertiary Care ◽  
Retrospective Chart Review ◽  
Safety Net ◽  
Tube Placement ◽  
Factors Affecting ◽  
Urban Safety

Objective: Myringotomy and tube insertion is a commonly practiced procedure within pediatric otolaryngology. Though relatively safe, follow-up appointments are critical in preventing further complications and monitoring for improvement. This study sought to evaluate the factors associated with compliance of post-myringotomy follow-up visits in an urban safety-net tertiary care setting. Methods: This study is a retrospective chart review conducted in outpatient otolaryngology clinic at an urban, safety-net, tertiary-care, academic medical center. All patients from ages 0 to 18 who received myringotomy and tube placement between February 3, 2012, to May 30, 2018 at the aforementioned clinic were included. Results: A total of 806 patients had myringotomy tubes placed during this period; 190 patients were excluded due to no visits being scheduled within 1 and 6 month visit windows post-operatively, leaving 616 patients included for analysis. Of 616 patients, 574 patients were seen for the 1-month visit, (42 patients did not have follow-up visits within the 1-month window), and 356 patients were examined for the 6-month visit (260 patients did not schedule follow-up visits within the 6-month window). For the 1-month follow-up visits post-procedure, only race/ethnicity type “Other” was associated with lower no-show rates (OR = 0.330, 95% CI: 0.093-0.968). With the 6-month follow-up visits, having private insurance (OR = 0.446, 95% CI: 0.229-0.867) and not having a 1-month visit scheduled (OR = 0.404, 95% CI: 0.174-0.937) predicted lower no-show rates. Conclusion: No meaningful factors studied were significantly associated with compliance of short-term, 1-month visits post-myringotomy. Compliance of longer-term, 6-month post-operative visits was associated with insurance type and previous visit status.

scholarly journals Promising results of stent graft placement for cephalic arch stenosis after repeated failure of angioplasty in patients on hemodialysis

2020 ◽  
Vol 48 (6) ◽  
pp. 030006052092041
Author(s):  
Pin-Chao Feng ◽  
Chun-Hui Lee ◽  
Hung-Chang Hsieh ◽  
Po-Jen Ko ◽  
Sheng-Yueh Yu ◽  
...  
Keyword(s):  
Stent Graft ◽  
Clinical Success ◽  
Medical Center ◽  
Retrospective Chart Review ◽  
Target Lesion ◽  
Primary Patency ◽  
Secondary Patency ◽  
Success Rates ◽  
Graft Placement ◽  
Significant Difference

Objective Cephalic arch stenosis (CAS) causes repeated dysfunction and failure of arteriovenous access. Percutaneous transluminal angioplasty is the standard initial treatment for CAS, but its outcome is unsatisfactory. This study aimed to evaluate the outcome of stent graft placement for CAS in patients on hemodialysis. Methods A retrospective chart review from a tertiary medical center was performed in patients receiving stent graft placement for CAS between January 2012 and 2016. Patency was analyzed using the Kaplan–Meier method. Results Twenty-one patients received stent graft placement for CAS. Technical and clinical success rates were 100%. Primary target lesion patency was 95% (95% confidence interval [CI], 86%–100%), 76% (95% CI, 58%–94%), and 43% (95% CI, 22%–64%) at 3, 6, and 12 months, respectively. No significant difference in patency was observed between the arteriovenous fistula and arteriovenous graft groups. Assisted primary patency was 95% (95% CI, 86%–100%), 71% (95% CI, 52%–91%), and 57% (95% CI, 36%–78%) at 3, 6, and 12 months, respectively. Secondary patency was 100% at 3, 6, and 12 months. Conclusions After repeated failed angioplasty for cephalic arch stenosis, patients on hemodialysis who receive stent graft placement have effective and durable outcomes.

S244 – Intraoperative ABR after Myringotomy and Tube Placement

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P157-P157
Author(s):  
Nanette Sturgill ◽  
Joshua G Yorgason ◽  
Albert H Park
Keyword(s):  
Middle Ear ◽  
Chart Review ◽  
Medical Center ◽  
Hearing Threshold ◽  
Retrospective Chart Review ◽  
Tube Placement ◽  
Threshold Levels ◽  
Time Of Surgery ◽  
The Difference

Objectives Understand the utility of intraoperative ABR testing after myringotomy and tube placement. Methods We performed a retrospective chart review of 27 patients (mean age 23 months) who underwent intraoperative ABR (ioABR) after myringotomy and tube placement at Primary Childrens Medical Center from 2004 to 2007. Paired t-tests were perfomed to analyze the difference in threshold levels from the ioABR to follow up behavioral audiometry at 1kHz and 4kHz frequencies, accounting for the presence or absence of fluid at the time of surgery. Results 15 patients (29 ears) showed a mean improvement of 10 dB at the 1 kHz frequency (p=0.007), and 16 patients (31 ears) improved by 5 dB at 4kHz (p=0.83). An improvement of at least 15 dB was seen in 45% of patients (13/29 ears) at 1 kHz and in 26% (8/31 ears) at 4 kHz; 5 patients improved by as much as 35–50 dB. Of the patients whose thresholds improved by at least 15 dB, 77% at 1 kHz and 83% at 4 kHz showed evidence of fluid at the time of the ioABR Conclusions Patients who undergo ioABR testing show a significant improvement of dB level on follow-up behavioral audiometry. Many patients whose hearing threshold improved by at least 15 dB had fluid at the time of myringotomy. Therefore, the presence of middle ear pathology may lead to an overestimation of ioABR thresholds. Consequently, ioABR results should be interpreted with caution in isolation, and subsequent audiometric testing should always be performed to validate prior results.

Abstract T P184: Outpatient Evaluation of Transient Ischemic Attack (TIA) Patients

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Nagakrishnal Nachimuthu ◽  
Michael E Chan ◽  
Martin I Amor ◽  
Alex Puma ◽  
Florence Armour ◽  
...  
Keyword(s):  
Medical Center ◽  
Cost Savings ◽  
Retrospective Chart Review ◽  
Final Diagnosis ◽  
Primary Diagnosis ◽  
Diagnostic Evaluation ◽  
First Year ◽  
Cerebrovascular Event ◽  
Lipid Panel

Objectives: We have started an open-access outpatient TIA Rapid Evaluation Center (TREC) at our community medical center. Patients referred to the TREC are seen on the next weekday and undergo a diagnostic evaluation then consultation with a stroke neurologist. The decision to refer a TIA patient to the TREC is left to the discretion of the attending physician. METHODS: We have collected prospective data from all TREC patients, including follow-up contact at 3 and 12 months to check for future cerebrovascular events. We performed a retrospective chart review on all patients admitted to the hospital with a primary diagnosis of TIA during the same period. This study had IRB approval. RESULTS: We saw 74 TREC patients within an average of 1.25 days of referral during its first year of operation, 56 from the emergency room and 18 from physician offices. Only 2 TREC patients needed admission to the hospital, the remainder completed their evaluation as out-patients. Only 1 TREC patient had a follow-up cerebrovascular event. During this same time period, 88 patients were admitted to the hospital with a primary diagnosis of TIA. Patients referred to the TREC had lower ABCD2 scores (average of 1.8 vs. 3.8, p <0.001) and were less likely to have a final diagnosis of TIA (19% vs. 77% p<0.001) than the hospitalized patients. More hospitalized TIA patients were seen on weekdays than weekends (74% vs. 27%). Nearly all patients underwent CT scan, lipid panel and EKG. However, TREC patients were more likely to undergo carotid ultrasound (99% vs. 84%, p=0.001) and MRI of the brain (89% vs. 68%, p=0.001). Hospital reimbursement from Medicare is $904 for a TREC patient and $5500 for a TIA hospitalization. CONCLUSIONS: 40% of all TIA patients at our hospital were referred to the TREC and seen within 1.25 days during its first year of operation. TIA patients referred to the TREC had lower ABCD2 scores and were less likely to have a final diagnosis of TIA. Day of the week seen did not influence the referral decision. TREC patients were more likely to have a complete diagnostic evaluation at a cost savings of $4600 for Medicare patients. Out-patient evaluation of TIA can be an efficient, safe, and less costly alternative to hospital admission.

Minitrephination as an Adjunctive Measure in the Endoscopic Management of Complex Frontal Sinus Disease

2007 ◽  
Vol 21 (5) ◽  
pp. 629-636 ◽  
Author(s):  
Alen N. Cohen ◽  
Marilene B. Wang
Keyword(s):  
Los Angeles ◽  
Frontal Sinus ◽  
Medical Center ◽  
Retrospective Chart Review ◽  
Sinus Surgery ◽  
Endoscopic Management ◽  
Fungal Sinusitis ◽  
Allergic Fungal Sinusitis ◽  
Sinus Disease

Background Frontal sinus disease and its surgical management continues to remain an area of controversy among rhinologists. This is evidenced by the multitude of surgical procedures, both external and endoscopic, that have been developed in its management. This study was performed to evaluate the safety and efficacy of frontal sinus minitrephination in combination with endoscopic frontal sinus exploration for the management of complex frontal sinus disease. Methods A retrospective chart review identified 13 patients treated with minitrephination, in conjunction with endoscopic frontal sinus exploration, at the University of California at Los Angeles Medical Center or West Los Angeles VA Medical Center from July 2004 to October 2005. Results Thirteen patients with diagnoses of chronic sinusitis (n = 10), nasal polyposis (n = 7), frontal mucocele (n = 4), allergic fungal sinusitis (n = 3), and inverting papilloma (n = 1) underwent either unilateral (n = 9) or bilateral (n = 4) minitrephination during primary or revision functional endoscopic sinus surgery. Median follow-up was 14.2 months. There were no complications attributed to the procedure, and all patients had improvement of their sinus symptoms and displayed no evidence of recurrence of their frontal sinus disease at last follow-up. Conclusion Minitrephination is a safe and effective adjunct in the management of complex frontal sinus disease, as it allows identification of the frontal recess and vigorous irrigation of the sinus contents.

scholarly journals Imaging-guided radiofrequency ablation of osteoid osteoma in typical and atypical sites: Long term follow up

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248589
Author(s):  
Francesco Somma ◽  
Vincenzo Stoia ◽  
Roberto D’Angelo ◽  
Francesco Fiore
Keyword(s):  
Radiofrequency Ablation ◽  
Osteoid Osteoma ◽  
Clinical Success ◽  
Major Complication ◽  
P Value ◽  
Navigation Systems ◽  
Technical Success ◽  
Dose Length Product ◽  
Operator Experience

Purpose To assess efficacy and safety of imaging-guided radiofrequency ablation (RFA) of Osteoid Osteoma (OO) in both typical and atypical sites. Methods and materials Between January 2014 and March 2019, 102 consecutive percutaneous RFA were performed and retrospectively reviewed. The procedures were performed using a RFA bipolar ablation system (Covidien, exposed tip of 0.7-1cm), under Computed Tomography (CT) guidance or using a navigation system (Masmec) under CT and Cone Beam CT (CBCT) guidance. Patients were followed up over 24 months. Clinical success and recurrences were considered on the base of established criteria. In patients with clinical failure and/or imaging evidence of relapse, retreatment was considered. Results Administered power per-procedure was ≤8 W (mean temperature, 90°C). The pre-procedure average value of visual analog scale (VAS) was 8.33+/-0.91. Primary and secondary success rate 96.08% (98/102) and100% (102/102), respectively. No major complication was described. Technical success was proved in every patient by CT scan acquisition after needle positioning. Relapse and tumour location were significantly correlated (p-value = 0.0165). The mean dose-length product was 751.55 mGycm2. Advanced bone healing was noted in 68 lesions after 1y-follow up and in 86 lesions after 2y-follow up. Conclusion Imaging-guided percutaneous RFA is a highly effective technique for OO, both in typical and atypical sites. CT or CBCT guidance, navigation systems and operator experience grant the technical success, which is the most crucial parameter affecting outcome.

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