scholarly journals Contribution of Imaging in Diagnosis of Primitive Cyst Hydatid in Unusual Localization: Pleura—A Report of Two Cases

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Fatima Zahra Mrabet ◽  
Jihane Achrane ◽  
Yassir Sabri ◽  
Fatima Ezzahra El Hassani ◽  
Sanaa Hammi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Hydatid Cyst ◽  
Spermatic Cord ◽  
Clinical Presentation ◽  
Young Patients ◽  
Cystic Masses ◽  
Cyst Hydatid ◽  
The Brain ◽  
Immunologic Tests

Hydatic disease has always been the most common in countries where large amount of sheep and cattle is raised, but increased travel and immigration have made this condition a serious worldwide public problem. Cyst hydatid may affect all parts of the human body like the heart, the bone marrow, the eye, the brain, the kidney, and the spermatic cord. Humans can become infested by accidentally ingesting the eggs that are passed in the feces from definitive hosts (usually a canid, such as a wolf, fox, or dog). Even in endemic countries, the primitive pleural hydatid cyst is exceptional, and it is very difficult to distinguish from other pleural and parietal cystic masses especially that in majority of cases the immunologic tests are negative. We report two cases of pleural hydatid cyst discovered in two young patients, with a nonspecific clinical presentation. The interest of this paper is to raise the primordial role of imaging in the positive diagnosis of primary pleural hydatid cyst.

scholarly journals Primary hydatid cyst of the psoas adherent to the aortoiliac axis: a real therapeutic challenge

2021 ◽  
Vol 7 (7) ◽  
pp. 363
Author(s):  
Anwar Rahali ◽  
Rahal Mssrouri ◽  
Marouane Baiss ◽  
Abderrahmane Mansouri ◽  
Hamid Mohamed ◽  
...  
Keyword(s):  
Literature Review ◽  
Hydatid Cyst ◽  
Rare Case ◽  
Essential Role ◽  
Histological Analysis ◽  
Clinical Presentation ◽  
Atypical Clinical Presentation ◽  
Residual Cavity ◽  
Primary Hydatid Cyst

<p class="abstract">Hydatidosis of the psoas is an unusual entity even in countries endemic to hydatid disease. We reported a rare case of hydatid cyst of psoas in a 54 year old man without pathological history. The atypical clinical presentation and the uncharacterizable radiology have demonstrated the essential role of surgery and histological analysis in the management of this type of lesion. The patient underwent a resection of the protruding dome with drainage of the residual cavity  because of the anatomical relationships of this hydatid cyst. Through this case and literature review, we aimed to discuss the diagnostic means, the natural course of the disease, the differential diagnoses as well as the therapeutic options for a hydatid cyst of the psoas.</p>

scholarly journals CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice

2020 ◽  
Vol 40 (1_suppl) ◽  
pp. S98-S116 ◽  
Author(s):  
Jordi Pedragosa ◽  
Francesc Miró-Mur ◽  
Amaia Otxoa-de-Amezaga ◽  
Carles Justicia ◽  
Francisca Ruíz-Jaén ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Ischemic Stroke ◽  
Functional Recovery ◽  
Behavioral Performance ◽  
Wild Type ◽  
Ischemic Brain ◽  
Arginase 1 ◽  
Angiogenic Genes ◽  
The Brain

Inflammatory Ly6ChiCCR2+ monocytes infiltrate the brain after stroke but their functions are not entirely clear. We report that CCR2+ monocytes and CCR2+ lymphocytes infiltrate the brain after permanent ischemia. To underscore the role of CCR2+ monocytes, we generated mice with selective CCR2 deletion in monocytes. One day post-ischemia, these mice showed less infiltrating monocytes and reduced expression of pro-inflammatory cytokines, markers of alternatively macrophage activation, and angiogenesis. Accordingly, Ly6Chi monocytes sorted from the brain of wild type mice 24 h post-ischemia expressed pro-inflammatory genes, M2 genes, and pro-angiogenic genes. Flow cytometry showed heterogeneous phenotypes within the infiltrating Ly6ChiCCR2+ monocytes, including a subgroup of Arginase-1+ cells. Mice with CCR2-deficient monocytes displayed a delayed inflammatory rebound 15 days post-ischemia that was not found in wild type mice. Furthermore, they showed reduced angiogenesis and worse behavioral performance. Administration of CCR2+/+ bone-marrow monocytes to mice with CCR2-deficient monocytes did not improve the behavioral performance suggesting that immature bone-marrow monocytes lack pro-reparative functions. The results show that CCR2+ monocytes contribute to acute post-ischemic inflammation and participate in functional recovery. The study unravels heterogeneity in the population of CCR2+ monocytes infiltrating the ischemic brain and suggests that pro-reparative monocyte subsets promote functional recovery after ischemic stroke.

scholarly journals Histopathology of brain AVMs part I: microhemorrhages and changes in the nidal vessels

2020 ◽  
Vol 162 (7) ◽  
pp. 1735-1740
Author(s):  
Patrik Järvelin ◽  
Roosa Wright ◽  
Henri Pekonen ◽  
Sara Keränen ◽  
Tuomas Rauramaa ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Clinical Course ◽  
Neutrophil Infiltration ◽  
Histopathological Changes ◽  
Tissue Samples ◽  
Perivascular Inflammation ◽  
History Of ◽  
Brain Avms ◽  
The Brain

Abstract Background Arteriovenous malformations of the brain (bAVM) may rupture from aneurysms or ectasias of the feeding, draining, or nidal vessels. Moreover, they may rupture from the immature, fragile nidal vessels that are characteristic to bAVMs. How the histopathological changes of the nidal vessels associate with clinical presentation and hemorrhage of the lesion is not well known. Materials and methods We investigated tissue samples from surgically treated bAVMs (n = 85) using standard histological and immunohistochemical stainings. Histological features were compared with the clinical presentation of the patient. Results Microhemorrhages from nidal vessels were found both in bAVMs with a history of clinically evident rupture and in bAVMs considered unruptured. These microhemorrhages were associated with presence of immature, pathological nidal vessels (p = 0.010) and perivascular inflammation of these vessels (p = 0.001), especially with adhesion of neutrophils (p < 0.001). In multivariate analysis, perivascular inflammation (OR = 19, 95% CI 1.6 to 230), neutrophil infiltration of the vessel wall (OR = 13, 95% CI 1.9 to 94), and rupture status (OR = 0.13, 95% CI 0.017 to 0.92) were significantly associated with microhemorrhages. Conclusions Clinically silent microhemorrhages from nidal vessels seem to be very common in bAVMs, and associate with perivascular inflammation and neutrophil infiltration. Further studies on the role of perivascular inflammation in the clinical course of bAVMs are indicated.

scholarly journals Extra-Axial Hematoma and Trimethoprim-Sulfamethoxazole Induced Aplastic Anemia: The Role of Hematological Diseases in Subdural and Epidural Hemorrhage

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Richard P. Menger ◽  
Rimal H. Dossani ◽  
Jai Deep Thakur ◽  
Frank Farokhi ◽  
Kevin Morrow ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Aplastic Anemia ◽  
Subdural Hematoma ◽  
Epidural Hematoma ◽  
Clinical Presentation ◽  
Rare Complication ◽  
Intracranial Hematoma ◽  
Hematological Diseases ◽  
Epidural Hemorrhage

Objective and Importance. To illustrate the development of spontaneous subdural hematoma secondary to aplastic anemia resulting from the administration of trimethoprim-sulfamethoxazole. This is the first report of trimethoprim-sulfamethoxazole potentiating coagulopathy leading to any form of intracranial hematoma.Clinical Presentation. A 62-year-old female developed a bone marrow biopsy confirmed diagnosis of aplastic anemia secondary to administration of trimethoprim-sulfamethoxazole following a canine bite. She then developed a course of waxing and waning mental status combined with headache and balance related falls. CT imaging of the head illustrated a 3.7 cm×6.6 mm left frontal subdural hematoma combined with a 7.0 mm×1.7 cm left temporal epidural hematoma.Conclusion. Aplastic anemia is a rare complication of the administration of trimethoprim-sulfamethoxazole. Thrombocytopenia, regardless of cause, is a risk factor for the development of spontaneous subdural hematoma. Given the lack of a significant traumatic mechanism, this subset of subdural hematoma is more suitable to conservative management.

The Role of Mitochondria in the Genesis of Neuroaxonal Dystrophy in the Brains of Aging Mice

1975 ◽  
Vol 33 ◽  
pp. 372-373
Author(s):  
J.E. Johnson
Keyword(s):  
Electron Microscopy ◽  
Present Report ◽  
Light And Electron Microscopy ◽  
Dorsal Column ◽  
Neuroaxonal Dystrophy ◽  
Nucleus Gracilis ◽  
Dystrophic Axons ◽  
The Brain ◽  
Nucleus Cuneatus

Although neuroaxonal dystrophy (NAD) has been examined by light and electron microscopy for years, the nature of the components in the dystrophic axons is not well understood. The present report examines nucleus gracilis and cuneatus (the dorsal column nuclei) in the brain stem of aging mice.Mice (C57BL/6J) were sacrificed by aldehyde perfusion at ages ranging from 3 months to 23 months. Several brain areas and parts of other organs were processed for electron microscopy.At 3 months of age, very little evidence of NAD can be discerned by light microscopy. At the EM level, a few axons are found to contain dystrophic material. By 23 months of age, the entire nucleus gracilis is filled with dystrophic axons. Much less NAD is seen in nucleus cuneatus by comparison. The most recurrent pattern of NAD is an enlarged profile, in the center of which is a mass of reticulated material (reticulated portion; or RP).

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