scholarly journals The Evolution of Central Retinal and Choroidal Thickness in Acute Anterior Uveitic Patients with Spondyloarthropathy

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Zsuzsanna Szepessy ◽  
Árpád Barsi ◽  
Kinga Kránitz ◽  
Zoltán Zsolt Nagy
Keyword(s):  
Treatment Period ◽  
Anterior Uveitis ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Anterior Segment ◽  
Cell Number ◽  
Acute Anterior Uveitis ◽  
Seronegative Spondyloarthropathy ◽  
Laser Flare

Purpose. To describe and correlate the degree of anterior segment inflammation with central retinal and choroidal thickness throughout the treatment period (in the course of follow-up) in the eyes affected with acute anterior uveitis in the patients with seronegative spondyloarthropathy (subgroup: ankylosing spondylitis). Methods. Thirty eyes of 30 consecutive Caucasian patients with HLA-B27-associated acute anterior uveitis were included in this study. The flare, AC cell number, and central retinal/choroidal thickness were determined at each visit by optical coherence tomography and laser flare photometry. Treatment consisted of topical corticosteroids. Statistical analysis was performed by MathWorks Matlab software. Results. In the follow-up period, central retinal thickness was increased in the first 9-10 days and then decreased until stabilization (after 5-6 weeks). The flare and AC cell number decreased rapidly at the beginning of the treatment, in the first 10 days, and thereafter, slower decrease could be observed until complete resolution of inflammation. Statistically significant, positive correlation was found between initial laser flare value and maximal central retinal thickness (r=0.881, p<0.001). Positive correlation between flare and retinal thickening was observable throughout the treatment period. Central choroidal thickness was decreased also significantly during the follow-up (p<0.001). Conclusions. The retina and choroid may play a biomarker function in the anterior segment inflammation of the eye in the patients with seronegative spondyloarthropathy.

Anterior Segment Fluorophotometry in Acute Anterior Uveitis

1987 ◽  
Vol 105 (11) ◽  
pp. 1550-1555 ◽  
Author(s):  
I. R. Fearnley ◽  
D. J. Spalton ◽  
S. E. Smith
Keyword(s):  
Anterior Uveitis ◽  
Anterior Segment ◽  
Acute Anterior Uveitis

scholarly journals Use of intracameral tenecteplase for rapid resolution of intraocular fibrin in acute anterior uveitis

2020 ◽  
Vol 2 (1) ◽  
pp. 42-47
Author(s):  
Wen Yee Lee ◽  
Wee Min Teh ◽  
Kiet Phang Ling ◽  
Norlina Mohd Ramli ◽  
Haslina Mohd Ali
Keyword(s):  
Visual Acuity ◽  
Anterior Chamber ◽  
Anterior Uveitis ◽  
Effective Means ◽  
Cost Effective ◽  
Acute Anterior Uveitis ◽  
Rapid Resolution ◽  
Fibrin Formation

Two patients presenting with acute anterior uveitis (AAU) and severe fibrinous reaction in the anterior chamber were given an injection of intracameral tenecteplase (50 microgram/0.1 ml). In both patients with AAU, complete rapid fibrin resolution and synechiolysis occurred within three days after intracameral tenecteplase injection. Significant visual acuity improvement was also seen in both patients and there were no complications observed throughout the follow-up duration of up to six months after administration of treatment. As tenecteplase has many superior properties compared to other medications in its class and can also be diluted and stored for up to a year under specific conditions, it may be an efficacious, safe and cost-effective means of treating severe AAU with fibrin formation.

Dynamics choroidal thickness in anterior uveitis without visible retinal changes

2021 ◽  
pp. 204-207
Author(s):  
E.V. Udovichenko ◽  
◽  
E.L. Sorokin ◽  
L.P. Danilova ◽  
◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Intraocular Pressure ◽  
Anterior Uveitis ◽  
Choroidal Thickness ◽  
Main Group ◽  
Hla B27 ◽  
Acute Anterior Uveitis ◽  
Corrected Visual Acuity ◽  
Best Corrected Visual Acuity

Purpose. To assess the state of the choroid in patients with HLA-B27-associated anterior uveitis without detectable lesions of the macular zone by ophthalmoscopy. Material and methods. 22 patients with HLA-B27-associated acute anterior uveitis without detectable changes in the macular zone by ophthalmoscopy – the main group. Age: 39.02±13.76 years, men – 16 and women – 8. Best corrected visual acuity varied from 0.1 to 0.5 (average 0.3). The level of intraocular pressure according to Maklakov in all eyes varied from 15 to 22 mm Hg. The parameters of paired intact eyes of patients served as a control. The subfoveal choroid thickness (CT) was determined using optical coherence tomography in comparison with paired intact eyes before treatment and 2 weeks after its initiation. Results. The initial values of the CT indexes in the main group varied from 337 to 371 μm, averaging 354±8 μm. This is statistically significantly higher than in intact paired eyes 255±7 μm (from 246 to 268 μm), p <0.001. 2 weeks after the start of treatment CT indexes in the main group were 268±10 μm, which was statistically significantly lower than the initial indexes in this group, p<0.001. In paired eyes, they were 254±6 μm. Conclusion. A statistically significant increase in CT was revealed in the eyes of patients with acute anterior uveitis, which statistically significantly exceeded the values of the paired intact eye on average on 100 μm. 2 weeks after the start of treatment, the CT indexes statistically significantly decreased to 268±10 μm, which did not differ statistically significantly from the CT indexes of the intact eye. Key words: anterior uveitis, HLA-B27, choroidal thickness.

scholarly journals Anterior segment optical coherence tomography in acute anterior uveitis

2014 ◽  
Vol 77 (1) ◽  
Author(s):  
Cristiana Agra ◽  
Lydianne Agra ◽  
Jeanine Dantas ◽  
Tiago Eugênio Faria e Arantes ◽  
João Lins de Andrade Neto
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Uveitis ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Acute Anterior Uveitis

scholarly journals Role of choroidal thickness assessment in unilateral acute anterior uveitis

2020 ◽  
Vol 68 (9) ◽  
pp. 1869
Author(s):  
Ranju Kharel (Sitaula) ◽  
Sunil Thapa ◽  
JyotiBaba Shrestha
Keyword(s):  
Anterior Uveitis ◽  
Choroidal Thickness ◽  
Acute Anterior Uveitis

Femto-assisted versus conventional phacoemulsification differently impact on choroid structure after surgery

2021 ◽  
pp. 112067212110483
Author(s):  
Romolo Appolloni ◽  
Pasquale Viggiano ◽  
Maria Luisa Carrella ◽  
Federica Evangelista ◽  
Alessandro Appolloni ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Cataract Surgery ◽  
Outcome Measures ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Cataract Extraction ◽  
Spectral Domain Oct ◽  
Significant Difference ◽  
Oct Imaging

Purpose: To report potential choroidal changes in eyes undergoing femtosecond laser cataract surgery (FLACS) and phacoemulsification surgery (PCS) by OCT. Methods: The patients were images by means Spectral Domain OCT imaging with EDI technology which may obtain OCT image. We exported a single EDI-OCT scan passing through the fovea and then it was imported into ImageJ program to perform a quantitative analysis. Main outcome measures: The main outcome measures were: (i) sub foveal choroidal thickness (SFCT); (ii) the choroidal vascularity index (CVI); and (iii) central retinal thickness (CRT). Results: At postoperative 1 week, FLACS group showed an increased CRT (241.2 ± 31.6–245.5 ± 36.4 µm; p = 0.016). Likewise, CVI and SFCT exhibited a slight increase but no statistically differences were highlighted ( p > 0.05). At the follow-up visit of 1 month, all OCT parameters did not display any significant difference ( p > 0.05). At post-operative 1 week, the PCS group displayed a significant increase in CRT, SFCT, and CVI. On the contrary, at the follow-up visit of 1-month, all choroidal parameters were characterized by a no statistically significant reduction ( p > 0.05). Conclusions: Our study exhibited a significant increase in CT and CVI in eyes that underwent conventional cataract surgery. Femtosecond laser-assisted cataract extraction did not result in macular change due to less postoperative inflammation.

Morphometric assessment of the state of the choroid in patients with anterior uveitis associated with the HLA-B27 Antigen

2021 ◽  
pp. 172-175
Author(s):  
E.V. Udovichenko ◽  
◽  
E.L. Sorokin ◽  
L.P. Danilova ◽  
◽  
...  
Keyword(s):  
Anterior Uveitis ◽  
Choroidal Thickness ◽  
Main Group ◽  
The State ◽  
Hla B27 ◽  
Acute Anterior Uveitis ◽  
Initial Values ◽  
Corrected Visual Acuity ◽  
Morphometric Assessment ◽  
Optical Coherence Tomograph

Purpose. To assess the state of the choroid in patients with anterior uveitis associated with the HLA-B27 Antigen, without ophthalmoscopically detectable lesions of the macular zone. Material and methods. 24 patients with acute anterior uveitis associated with HLA-B27 Antigen, without ophthalmologically detectable changes in the macular zone. The average age of the patients was 39.02±13.76 years. There were 16 men and 8 women. Maximum corrected visual acuity ranged from 0.1 to 0.5. The level of intraocular pressure according to Maklakov varied from 15 to 22 mm Hg. The subfoveal choroidal thickness (SCT) was determined using an optical coherence tomograph in comparison with paired intact eyes before treatment and 2 weeks after its initiation. Results. The initial values of the SCT index in the main group varied from 337 to 371 µm, averaging 354±8 µm. This is statistically significantly higher than in intact paired eyes (255±7 µm; from 246 to 268 µm; p<0.001). 2 weeks after the start of treatment, the SCT index in the main group was 268±10 µm, which was statistically significantly lower than the initial values in this group (p<0.001). Conclusion. A statistically significant increase in SCT was revealed in the eyes of patients with acute anterior uveitis. 2 weeks after the start of treatment, the SCT index statistically significantly decreased to 268±10 µm, which did not statistically significantly differ from that of the intact eye. Key words:anterior uveitis, HLA-B27 Antigen, subfoveolar thickness of the choroid.

Long-term visual and anatomic outcomes of patients with peripapillary pachychoroid syndrome

2020 ◽  
pp. bjophthalmol-2019-315550
Author(s):  
David Xu ◽  
Elisha Garg ◽  
Kook Lee ◽  
Yoichi Sakurada ◽  
Atchara Amphornphruet ◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Outer Nuclear Layer ◽  
Temporal Trends ◽  
Visual Outcome ◽  
Choroidal Thickening ◽  
Disease Spectrum ◽  
Endothelial Growth Factor

Background/AimsTo analyse the long-term anatomic and visual outcomes of patients with peripapillary pachychoroid syndrome (PPS), a recently described entity in the pachychoroid disease spectrum.MethodsThis study retrospectively included patients from several retina centres worldwide. Visual acuity (VA), retinal thickness and choroidal thickness at baseline, 6 months and final follow-up were assessed. Temporal trends in VA and anatomic characteristics were evaluated. Visual and anatomic outcomes in eyes that were observed versus those that were treated were analysed.ResultsFifty-six eyes of 35 patients were included with mean follow-up of 27±17 months. Median VA was 20/36 at baseline and remained stable through follow-up (p=0.77). Retinal thickness significantly decreased subfoveally (p=0.012), 1.5 mm nasal to the fovea (p=0.002) and 3.0 mm nasal to the fovea (p=0.0035) corresponding to areas of increased thickening at baseline. Choroidal thickness significantly decreased subfoveally (p=0.0030) and 1.5 mm nasal to the fovea (p=0.0030). Forty-three eyes were treated with modalities including antivascular endothelial growth factor injection, photodynamic therapy, and others. VA remained stable in treated eyes over follow-up (p=0.67). An isolated peripapillary fluid pocket in the outer nuclear layer was characteristic of PPS.ConclusionPatients with PPS experienced decreased retinal oedema and decreased choroidal thickening throughout the course of disease. While some patients experienced visual decline, the overall visual outcome was relatively favourable and independent of trends in retinal or choroidal thickening.

Sign in / Sign up

Export Citation Format

Share Document