scholarly journals Role of Simulations in the Treatment Planning of Radiofrequency Hyperthermia Therapy in Clinics

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Bibin Prasad ◽  
Jung Kyung Kim ◽  
Suzy Kim
Keyword(s):  
Treatment Planning ◽  
Human Anatomy ◽  
Clinical Aspects ◽  
Phase Array ◽  
Clinical Use ◽  
Hyperthermia Treatment ◽  
Tissue Properties ◽  
Hyperthermia Therapy ◽  
Radiofrequency Hyperthermia ◽  
Effective Development

Hyperthermia therapy is a treatment modality in which tumor temperatures are elevated to higher temperatures to cause damage to cancerous tissues. Numerical simulations are integral in the development of hyperthermia treatment systems and in clinical treatment planning. In this study, simulations in radiofrequency hyperthermia therapy are reviewed in terms of their technical development and clinical aspects for effective clinical use. This review offers an overview of mathematical models and the importance of tissue properties; locoregional mild hyperthermia therapy, including phantom and realistic human anatomy models; phase array systems; tissue damage; thermal dose analysis; and thermoradiotherapy planning. This review details the improvements in numerical approaches in treatment planning and their application for effective clinical use. Furthermore, the modeling of thermoradiotherapy planning, which can be integrated with radiotherapy to provide combined hyperthermia and radiotherapy treatment planning strategies, are also discussed. This review may contribute to the effective development of thermoradiotherapy planning in clinics.

scholarly journals Hyperthermia treatment planning for cervical cancer patients based on electrical conductivity tissue properties acquiredin vivowith EPT at 3 T MRI

2016 ◽  
Vol 32 (5) ◽  
pp. 558-568 ◽  
Author(s):  
Edmond Balidemaj ◽  
Henny Petra Kok ◽  
Gerben Schooneveldt ◽  
Astrid L.H.M.W. van Lier ◽  
Rob F. Remis ◽  
...  
Keyword(s):  
Electrical Conductivity ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
Treatment Planning ◽  
Hyperthermia Treatment ◽  
Tissue Properties

Clinical use of the hyperthermia treatment planning system HyperPlan to predict effectiveness and toxicity

2003 ◽  
Vol 55 (2) ◽  
pp. 407-419 ◽  
Author(s):  
Geetha Sreenivasa ◽  
Johanna Gellermann ◽  
Beate Rau ◽  
Jacek Nadobny ◽  
Peter Schlag ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Planning System ◽  
Treatment Planning System ◽  
Clinical Use ◽  
Hyperthermia Treatment

scholarly journals Nanoparticles in enhancing microwave imaging and microwave Hyperthermia effect for liver cancer treatment

2021 ◽  
Vol 60 (1) ◽  
pp. 223-236
Author(s):  
Walaa Maamoun ◽  
Mohamed I. Badawi ◽  
Ayman A Aly ◽  
Y. Khedr
Keyword(s):  
Silver Nanoparticles ◽  
Liver Cancer ◽  
Cancer Treatment ◽  
Electromagnetic Waves ◽  
Microwave Imaging ◽  
Healthy Tissue ◽  
Cancer Tissue ◽  
Hyperthermia Treatment ◽  
Hyperthermia Therapy ◽  
Surrounding Healthy Tissue

Abstract Hyperthermia therapy is a promising therapy for liver cancer treatment that utilizes external electromagnetic waves to heat the tumor zone to preferentially kill or minimize cancer cells. Nevertheless, it’s a challenge to realize localized heating of the cancer tissue without harming the surrounding healthy tissue. This research proposes to utilize nanoparticles as microwave absorbers to enhance microwave imaging and achieve localized hyperthermia therapy. A realistic 3D abdomen model has been segmented using 3D Slicer segmentation software, and then the obtained segmented CAD model exported to Computer Simulation Technology (CST STUDIO) for applying the Finite Element Modeling (FEM). Next investigating both imaging and treatment capability. Finally, the specific absorption rate (SAR) and temperature distribution were computed without nanoparticles and with different types of nanoparticles such as gold (GNPs) and silver nanoparticles at frequency 915 MHz. By comparing the achived results, it was seen that Silver nanoparticles can make a great enhancement in raising the temperature. However, this result was unsatisfactory but, after adding gold nanoparticles the temperature exceed 42°C, at frequency 915 MHz which is achieving the hyperthermia treatment without harming the nearby healthy tissue, GNPs also can achieve a great enhancement in SAR result

scholarly journals Clinical validation of a novel thermophysical bladder model designed to improve the accuracy of hyperthermia treatment planning in the pelvic region

2018 ◽  
Vol 35 (1) ◽  
pp. 383-397 ◽  
Author(s):  
Gerben Schooneveldt ◽  
H. Petra Kok ◽  
Akke Bakker ◽  
Elisabeth D. Geijsen ◽  
Coen R. N. Rasch ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Clinical Validation ◽  
Hyperthermia Treatment ◽  
Pelvic Region ◽  
Bladder Model

scholarly journals The potential of constrained SAR focusing for hyperthermia treatment planning: analysis for the head & neck region

2018 ◽  
Vol 64 (1) ◽  
pp. 015013 ◽  
Author(s):  
G G Bellizzi ◽  
T Drizdal ◽  
G C van Rhoon ◽  
L Crocco ◽  
T Isernia ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Neck Region ◽  
Hyperthermia Treatment ◽  
Head Neck

scholarly journals Towards the Immunogenic Hyperthermic Action: Modulated ElectroHyperthermia

2020 ◽  
pp. 1-6
Author(s):  
Andras Szasz ◽  
Andras Szasz
Keyword(s):  
Cancer Cells ◽  
Solid Tumors ◽  
Phase Ii ◽  
Immune Cells ◽  
Genetic Information ◽  
Clinical Applications ◽  
Clinical Use ◽  
Hyperthermia Treatment ◽  
Broad Perspective ◽  
Trade Name

Hyperthermia treatment for solid tumors is a long-used, but poorly accepted method in clinical use. Modulated electro-hyperthermia (mEHT, trade name: oncothermia®) changes the paradigm, introduces a novel, cellularly selective and immunogenic cell-ruination. The mEHT method produces tumor-vaccination, presenting the unharmed genetic information of cancer cells to immune cells [1]. The mEHT method is approved in more than 30 countries. Its phase II/III clinical applications indicate a broad perspective.

Clinical use of a commercial Monte Carlo treatment planning system for electron beams

2005 ◽  
Vol 50 (5) ◽  
pp. 1029-1034 ◽  
Author(s):  
J E Cygler ◽  
C Lochrin ◽  
G M Daskalov ◽  
M Howard ◽  
R Zohr ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Treatment Planning ◽  
Electron Beams ◽  
Planning System ◽  
Treatment Planning System ◽  
Clinical Use

Improving hyperthermia treatment planning for the pelvis by accurate fluid modeling

2016 ◽  
Vol 43 (10) ◽  
pp. 5442-5452 ◽  
Author(s):  
G. Schooneveldt ◽  
H. P. Kok ◽  
E. Balidemaj ◽  
E. D. Geijsen ◽  
F. van Ommen ◽  
...  
Keyword(s):  
Treatment Planning ◽  
Hyperthermia Treatment ◽  
Fluid Modeling
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