scholarly journals A Case of a Stafne Bone Defect Associated with Sublingual Glands in the Lingual Side of the Mandible

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Kamichika Hayashi ◽  
Takeshi Onda ◽  
Takahiro Iwasaki ◽  
Mitsuru Takata ◽  
Kiyotaka Mori ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Bone Defect ◽  
Traffic Accident ◽  
Lingual Side ◽  
Salivary Gland Tissue ◽  
Gland Tissue ◽  
Magnetic Resonance Imaging Mri ◽  
The Right ◽  
Similar Signal Intensity ◽  
Stafne Bone Defect

A Stafne bone defect from the mandibular anterior to the premolar region is an extremely rare case. A case of a Stafne bone defect extending from the mandibular anterior to the premolar region was presented. Computed tomography (CT) and magnetic resonance imaging (MRI) suggested that salivary gland tissue connected to the sublingual glands was involved in the formation of the cavity. The patient was a 68-year-old man who was examined at our hospital’s emergency outpatient department after a traffic accident. He was referred to our department for the treatment of contusions of the lips and oral cavity. A bone defect in the lingual side of the mandible from the right anterior to the right premolar region was incidentally detected on CT. CT showed a rounded cavity in the lingual side of the mandible that had a lingual opening, was monocystic, and had a cortical margin. The margin of the cavity was relatively dull and regular. MRI showed that the tissue filling the cavity in the lingual side of the mandible had similar signal intensity as the sublingual glands and was contiguous with the normal sublingual glands. Based on these findings, the bone defect was diagnosed as a Stafne bone defect filled with salivary gland tissue connected to the sublingual gland tissue.

scholarly journals A case report of ectopic salivary gland tissue in the larynx

2021 ◽  
Vol 2 (4) ◽  
Author(s):  
Sleurs K ◽  
◽  
Heijden S Van Der ◽  
Vries B De ◽  
Smit J ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Salivary Gland ◽  
Vocal Fold ◽  
Histopathological Examination ◽  
Anterior Portion ◽  
Salivary Gland Tissue ◽  
Gland Tissue ◽  
Submucosal Mass ◽  
The Right ◽  
False Vocal

Submucosal laryngeal masses are challenging for ENT specialists as the diagnosis usually remains uncertain until histopathological examination is carried out. We report a case of a 54-year old man complaining of dysphonia and globus sensation. Flexible laryngoscopic examination showed a submucosal swelling in the right anterior laryngeal ventricle. Microlaryngoscopic excision of the submucosal mass was performed. Histological examination revealed salivary gland tissue. We found only a few cases in the literature of ectopic salivary gland tissue situated in the larynx. In these cases, the salivary gland tissue was also located at the anterior portion of the true or false vocal fold. Thus, it is necessary to consider this condition in the differential diagnosis of a submucosal mass in the anterior true or false vocal fold or laryngeal ventricle.

Hyperglycemia Induces Generation of Reactive Oxygen Species and Accelerates Apoptotic Cell Death in Salivary Gland Cells

Pathobiology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Naoyuki Matsumoto ◽  
Daisuke Omagari ◽  
Ryoko Ushikoshi-Nakayama ◽  
Tomoe Yamazaki ◽  
Hiroko Inoue ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Salivary Gland ◽  
Tissue Injury ◽  
Ros Production ◽  
Oxygen Species ◽  
Saliva Secretion ◽  
Salivary Gland Tissue ◽  
Gland Tissue

<b><i>Introduction:</i></b> Type-2 diabetes mellitus (T2DM) is associated with several systemic vascular symptoms and xerostomia. It is considered that hyperglycemia-induced polyuria and dehydration cause decreased body-water volume, leading to decreased saliva secretion and, ultimately, xerostomia. In T2DM, increased production of reactive oxygen species (ROS) causes tissue damage to vascular endothelial cells as well as epithelial tissue, including pancreas and cornea. Hence, a similar phenomenon may occur in other tissues and glands in a hyperglycemic environment. <b><i>Methods:</i></b> Salivary gland tissue injury was examined, using T2DM model mouse (db/db). Transferase‐mediated dUTP nick‐end labeling (TUNEL) was conducted to evaluate tissue injury. The levels of malondialdehyde (MDA) and 8-hydroxy-2′-deoxyguanosine, Bax/Bcl-2 ratio were measured as indicator of oxidative stress. Moreover, in vitro ROS production and cell injury was evaluated by mouse salivary gland-derived normal cells under high-glucose condition culture. <b><i>Results:</i></b> In vivo and in vitro analysis showed a higher percentage of TUNEL-positive cells and higher levels of MDA and 8-hydroxy-2′-deoxyguanosine in salivary gland tissue of db/db mice. This suggests damage of saliva secretion-associated lipids and DNA by hyperglycemic-induced oxidative stress. To analyze the mechanism by which hyperglycemia promotes ROS production, mouse salivary gland-derived cells were isolated. The cell culture with high-glucose medium enhanced ROS production and promotes apoptotic and necrotic cell death. <b><i>Conclusion:</i></b> These findings suggest a novel mechanism whereby hyperglycemic-induced ROS production promotes salivary gland injury, resulting in hyposalivation.

Salivary Gland Tissue Engineering and Future Diagnostics

2015 ◽  
pp. 157-185 ◽  
Author(s):  
Daniel A. Harrington ◽  
Mariane Martinez ◽  
Danielle Wu ◽  
Swati Pradhan-Bhatt ◽  
Mary C. Farach-Carson
Keyword(s):  
Tissue Engineering ◽  
Salivary Gland ◽  
Salivary Gland Tissue ◽  
Gland Tissue

scholarly journals Shotgun Proteomics Analysis of Saliva and Salivary Gland Tissue from the Common Octopus Octopus vulgaris

2018 ◽  
Vol 17 (11) ◽  
pp. 3866-3876 ◽  
Author(s):  
Legana C. H. W. Fingerhut ◽  
Jan M. Strugnell ◽  
Pierre Faou ◽  
Álvaro Roura Labiaga ◽  
Jia Zhang ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Shotgun Proteomics ◽  
Octopus Vulgaris ◽  
Proteomics Analysis ◽  
Salivary Gland Tissue ◽  
Gland Tissue ◽  
The Common ◽  
Common Octopus

Comparison of Labial Minor Salivary Gland Biopsies from Childhood Sjögren Syndrome and Age-matched Controls

2014 ◽  
Vol 41 (6) ◽  
pp. 1178-1182 ◽  
Author(s):  
Naoto Yokogawa ◽  
Scott M. Lieberman ◽  
Faizan Alawi ◽  
Sharon Bout-Tabaku ◽  
Marta Guttenberg ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Minor Salivary Gland ◽  
Sjögren Syndrome ◽  
Classification Criteria ◽  
Sjogren Syndrome ◽  
Labial Salivary Gland ◽  
Focus Score ◽  
Salivary Gland Tissue ◽  
Gland Tissue ◽  
Control Samples

Objective.To determine an appropriate focus score cutoff for childhood Sjögren syndrome (SS).Methods.Labial salivary gland tissue from specimens from children with SS and age-matched controls was retrospectively identified and reviewed by a blinded oral pathologist.Results.The presence of any focal sialadenitis (focus score > 0 foci/4 mm2) was common among childhood SS samples but present in only 1 of 8 control samples.Conclusion.The presence of any focal lymphocytic sialadenitis in minor labial salivary gland tissue is suggestive of childhood SS and should be included in future childhood SS-specific diagnostic or classification criteria.

Aberrant salivary gland tissue in mandible

1957 ◽  
Vol 10 (10) ◽  
pp. 1086-1090 ◽  
Author(s):  
Euclid L. Richard ◽  
Joseph Ziskind
Keyword(s):  
Salivary Gland ◽  
Salivary Gland Tissue ◽  
Gland Tissue
Sign in / Sign up

Export Citation Format

Share Document