Application of Pet-CT Fusion Deep Learning Imaging in Precise Radiotherapy of Thyroid Cancer

This article explores the value of wall F-FDG PET/Cr imaging in the diagnosis of thyroid cancer, studies its ability to distinguish benign and malignant thyroid lesions, and seeks ways to improve the accuracy of diagnosis. The normal control group selected 40 patients who came to our center for physical examination. In the normal control group, the average value of the standard uptake value of both sides of the thyroid was used as the SUV of the thyroid gland and the highest SUV value of the patient's lesion (SUV max) represented the SUV of the lesion. After injection of imaging agent 18F-FD1G, routine imaging was performed at 1h, time-lapse imaging was performed at 2.5 h, and the changes with conventional imaging were compared to infer the benign and malignant lesions. We used SPSS software to carry out statistical analysis, respectively, carrying out analysis of variance, paired t-test, independent sample t-test, and linear correlation analysis. In the thyroid cancer group, 87.5% of the delayed imaging SUV was higher than the conventional imaging SUV, while 83.33% of the benign disease group had a lower SUV than the conventional imaging SUV. 18F-FDG PET/CT imaging has higher sensitivity and specificity for the diagnosis of recurrence or metastasis in patients with Tg positive. However, it has lower sensitivity and specificity for the diagnosis of 131I-Dx-WBS negative DTC and 18F-FDG PET/CT. The specificity increases with the increase of serum Tg level. The above results confirm that 18F-FDG PET/CT imaging is of great significance for the diagnosis of recurrence or metastasis in patients; with PET/CT imaging, the results changed 16.13% of the Tg-positive and 131I-Dx-WBS negative DTC patients' later treatment decision. The decision-making and curative effect evaluation have certain value.

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18F FDG PET-CT Imaging in Tuberculosis

Bangladesh Journal of Nuclear Medicine ◽

10.3329/bjnm.v19i2.36011 ◽

2018 ◽

Vol 19 (2) ◽

pp. 135

Author(s):

Shamim MF Begum ◽

Md Abdus Shakur Khan

Keyword(s):

Computed Tomography ◽

Fdg Pet ◽

Ct Imaging ◽

Medical Emergency ◽

Imaging Features ◽

Conventional Imaging ◽

Imaging Tool ◽

Pet Ct ◽

18F Fdg ◽

Fdg Pet Ct

<p>Tuberculosis (TB) is the second highest infective cause of death worldwide and the global impact of TB is very important. Among all the TB burden WHO regions, 40% TB cases accounts in the South East Asian region. It has become a medical emergency not only in developing countries but also in some high-income countries. The rising incidence of multidrug resistance (MDR) TB and HIV co-infection has increased the morbidity and mortality of TB despite the availability of cheap and effective treatment. The diagnosis of active TB is almost similar over the world. Conventional radiography and Computed Tomography (CT) imaging play a crucial role in the diagnosis of TB. But these conventional imaging are often nonspecific and unable to provide a definitive diagnosis in cases of atypical and heterogeneous presentation. The signs of TB may mimic other diseases in conventional imaging. The introduction of new imaging tool Fluorine18 Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (18F FDG PET-CT) opens the door to evaluate its potentiality application in TB. The role of this new imaging tool in TB imaging has been well documented. 18F FDG PET-CT may assist in early diagnosis, facilitate differentiation between malignancies and TB, identification of extrapulmonary TB, staging of TB, and in assessment of treatment response. Therefore, familiarity with the spectrum of imaging features and understanding the use of 18F FDG PET-CT in diagnosis and management of TB is important, especially for referring clinicians and the reporting nuclear medicine specialists in TB burden country like Bangladesh. This article reviews the main applications, pattern of imaging spectrum with limitations of 18F FDG PET-CT in TB.</p><p>Bangladesh J. Nuclear Med. 19(2): 135-140, July 2016</p>

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Dual-Time 18F-FDG PET/CT Imaging in Initial Locoregional Staging of Breast Carcinoma: Comparison with Conventional Imaging and Pathological Prognostic Factors

Indian Journal of Surgery ◽

10.1007/s12262-016-1486-x ◽

2016 ◽

Vol 78 (5) ◽

pp. 382-389 ◽

Cited By ~ 5

Author(s):

Aynur Ozen ◽

Serdar Altinay ◽

Ozgul Ekmekcioglu ◽

Ramazan Albayrak ◽

Ali Muhammedoglu ◽

...

Keyword(s):

Prognostic Factors ◽

Breast Carcinoma ◽

Fdg Pet ◽

Ct Imaging ◽

Conventional Imaging ◽

Pet Ct ◽

18F Fdg ◽

Fdg Pet Ct ◽

Locoregional Staging

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Optimal threshold of stimulated serum thyroglobulin level for 18F-FDG PET/CT imaging in patients with thyroid cancer

Journal of Huazhong University of Science and Technology [Medical Sciences] ◽

10.1007/s11596-017-1752-6 ◽

2017 ◽

Vol 37 (3) ◽

pp. 429-432

Author(s):

Hong Chai ◽

Hu Zhang ◽

Yong-li Yu ◽

Yun-chao Gao

Keyword(s):

Thyroid Cancer ◽

Fdg Pet ◽

Ct Imaging ◽

Optimal Threshold ◽

Serum Thyroglobulin ◽

Pet Ct ◽

Thyroglobulin Level ◽

18F Fdg ◽

Fdg Pet Ct

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Time-Related Aortic Inflammatory Response, As Assessed With 18F-FDG PET/CT, in Patients Hospitalized With Severe or Critical COVID-19 The COVAIR Study

10.21203/rs.3.rs-996657/v1 ◽

2021 ◽

Author(s):

Charalambos Vlachopoulos ◽

Dimitrios Terentes - Printzios ◽

Paraskevi Katsaounou ◽

Eirini Solomou ◽

Vassiliki Gardikioti ◽

...

Keyword(s):

Fdg Pet ◽

Ct Imaging ◽

Control Group ◽

Prior History ◽

Fdg Uptake ◽

Positron Emission ◽

Pet Ct ◽

Arterial Inflammation ◽

18F Fdg ◽

Fdg Pet Ct

Abstract AimArterial involvement has been implicated in the coronavirus disease of 2019 (COVID-19). 18F-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging is a valuable tool for the assessment of disease severity in different types of vasculitis and is a predictor of outcome. We sought to prospectively assess the presence of aortic inflammation and its time-dependent trend by measuring the 18-FDG uptake in PET/CT in patients with severe or critical COVID-19.Methods In this pilot case control study, we recruited 20 patients, who were admitted with severe or critical COVID-19 illness. Patients underwent imaging between 20 to 120 days after hospital admission. Ten age- and sex-matched individuals with prior history of malignancy but free of active disease served as the control group. Arterial inflammation was assessed by measuring 18-FDG uptake in PET/CT and calculating aortic target to blood ratio (TBR).ResultsThere was a significant correlation between aortic TBR values and time distance from diagnosis to 18F-FDG PET/CT scan (-rho- =0.547, p=0.015) even after adjustment for confounders (p=0.002). Patients who were scanned less than 60 days (median) from diagnosis had significantly higher TBR values compared to patients examined more than 60 days post-diagnosis (1.55 [1.47-1.61] vs 1.40 [1.33-1.45], respectively, p=0.013).ConclusionThis is the first study suggesting that 18 FDG PET/CT imaging could be used for assessment of arterial inflammation in patients with severe/critical COVID-19. These findings may have important implications for the understanding of the pathophysiology and the course of the disease and for improving our preventive and therapeutic strategies.

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