scholarly journals Mature Ovarian Teratoma: Neurological Implications in a Young Woman

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Michele Carlo Schiavi ◽  
Fabio Manganelli ◽  
Claudia Morgani ◽  
Pietro Cignini ◽  
Veronica Yacoub ◽  
...  
Keyword(s):  
Laparoscopic Surgery ◽  
Nmda Receptors ◽  
Young Woman ◽  
Multidisciplinary Approach ◽  
Ovarian Teratoma ◽  
Autoimmune Syndrome ◽  
Nmdar Encephalitis ◽  
Mature Ovarian Teratoma

Anti-NMDAR encephalitis is an autoimmune syndrome associated with antibodies against NMDA receptors. In some cases, it is associated with various tumors; one of them is ovarian teratoma, which mostly affects women below the age of 30 years. Here, we report a case of ovarian teratoma associated with anti-NMDAR encephalitis treated with both laparoscopic surgery and immunotherapy. Multidisciplinary approach is the cornerstone for the management of this syndrome.

scholarly journals Expression of Various Glutamate Receptors Including N-Methyl-D-Aspartate Receptor (NMDAR) in an Ovarian Teratoma Removed from a Young Woman with Anti-NMDAR Encephalitis

2010 ◽  
Vol 49 (19) ◽  
pp. 2167-2173 ◽  
Author(s):  
Naoko Tachibana ◽  
Takashi Shirakawa ◽  
Keiko Ishii ◽  
Yukitoshi Takahashi ◽  
Keiko Tanaka ◽  
...  
Keyword(s):  
Glutamate Receptors ◽  
Young Woman ◽  
Ovarian Teratoma ◽  
Aspartate Receptor ◽  
Nmdar Encephalitis

scholarly journals Anti-N-Methyl-D-Aspartate Receptor Encephalitis with Decrease in Blood Flow in Cerebellum

2021 ◽  
pp. 17-23
Author(s):  
Koji Obara ◽  
Tomoko Ono ◽  
Itaru Toyoshima
Keyword(s):  
Working Memory ◽  
Blood Flow ◽  
Ovarian Teratoma ◽  
Emission Computed Tomography ◽  
High Dose ◽  
Promising Alternative ◽  
Flow Monitoring ◽  
Aspartate Receptor ◽  
Nmdar Encephalitis ◽  
Consciousness Disturbance

In anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, progressive cerebellar atrophy potentially leads to severe sequelae. We encountered a patient with anti-NMDAR antibody encephalitis who showed a decrease of blood flow in the cerebellum. A 15-year-old girl presented with consciousness disturbance. Influenza encephalopathy was suspected, and she was treated with glucocorticoid pulse therapy, high-dose intravenous immunoglobulins, and plasma exchange sequentially. She subsequently underwent left oophorectomy due to the presence of anti-NMDAR antibodies and a left ovarian teratoma. In spite of the surgery, her neuropsychiatric symptoms persisted, and she recovered slowly after the introduction of oral methotrexate (MTX). Sequential cerebral blood flow monitoring with single-photon emission computed tomography showed marked cerebellar hypoperfusion. Although mild impairments including working memory and verbal fluency persisted, she eventually returned to high school 3 years after onset. Profound cerebellar hypoperfusion including lobules VI and VII may be the reason for her working memory impairment and speaking problems. Oral MTX may be a promising alternative treatment for some refractory cases of anti-NMDAR encephalitis.

Does MAP2 have a Role in Predicting the Development of Anti-NMDAR Encephalitis Associated with Benign Ovarian Teratoma? A Report of Six New Pediatric Cases

2015 ◽  
Vol 18 (2) ◽  
pp. 122-126 ◽  
Author(s):  
Caitlin A. Cundiff ◽  
Nancy Elawabdeh ◽  
Mina M. Naguib ◽  
Samuel N. Jactel ◽  
Dina El Demellawy ◽  
...  
Keyword(s):  
Ovarian Teratoma ◽  
Nmdar Encephalitis

scholarly journals Anti-n-Methyl-d-Aspartate-Receptor (NMDAR) Encephalitis in Association with Ovarian Teratoma

Cureus ◽  
2017 ◽  
Author(s):  
Javaad Ahmad ◽  
Muhammad Saad Sohail ◽  
Amina Khan ◽  
Ahmed H Qavi ◽  
Pramod Gaudel ◽  
...  
Keyword(s):  
Ovarian Teratoma ◽  
Aspartate Receptor ◽  
Nmdar Encephalitis

scholarly journals Remove the Ovarian Tumor, Cure the Encephalitis: Anti-NMDAR Encephalitis With Ovarian Teratoma in a Tertiary Hospital in Singapore

2017 ◽  
Vol 8 (2) ◽  
pp. 52-57
Author(s):  
Ka Hee Chua ◽  
Andy Wei Keat Tan ◽  
Serene Liqing Lim ◽  
Wahab Syed Shahul Hameed ◽  
Siew Ju See ◽  
...  
Keyword(s):  
Ovarian Tumor ◽  
Tertiary Hospital ◽  
Ovarian Teratoma ◽  
Nmdar Encephalitis

Anti-N-methyl-D-aspartate receptor encephalitis and ovarian teratomas: is there any association?

2020 ◽  
Vol 19 (5) ◽  
pp. 124-131
Author(s):  
N.M. Podzolkova ◽  
◽  
V.V. Korennaya ◽  
O.S. Levin ◽  
E.E. Vasenina ◽  
...  
Keyword(s):  
Pathological Condition ◽  
Rare Complication ◽  
Autoimmune Encephalitis ◽  
Neurological Deficits ◽  
Ovarian Teratoma ◽  
Aspartate Receptor ◽  
Nmdar Encephalitis ◽  
Life Threatening ◽  
Causal Treatment ◽  
Ovarian Teratomas

This article aims to explore the problem of anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis and also describes our own experience in treating anti-NMDAR encephalitis in patients with ovarian teratomas. This pathological condition is a rare complication of cancer. Practicing gynecologists are often unfamiliar with it, although its consequences can be life-threatening. Early diagnosis and causal treatment, particularly teratoma removal, are critical for the outcome and can prevent death or the development of neurological deficits in patients. Key words: anti-NMDAR, autoimmune encephalitis, ovarian cysts, complications, ovarian teratoma, encephalitis, encephalitis in women

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